Download or read book Handbook of Immunological Properties of Engineered Nanomaterials Second Edition in 3 Volumes written by Marina A Dobrovolskaia and published by . This book was released on 2016-01-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides comprehensive overview of the field of immunology related to engineered nanomaterials used for biomedical applications. It contains literature review, case studies and protocols. The book can serve as a source of information about nanoimmunotoxicology for both junior scientists and experts in the field. The authors have more than 10 years of experience with preclinical characterization of engineered nanomaterials used for medical applications, and they share their experience with the readers. In addition, the international team of experts in the field provides the opinion and share the expertise on individual topics related to nanoparticle physicochemical characterization, hematocompatibility, and effects on the immune cell function . The second edition contains updated chapters from the first edition plus new chapters covering areas of tumor immunology, nanoparticle interaction with lymphatic system, mathematical modeling of protein corona, utilization of nanoparticles for the delivery of antiviral drugs, extensive analysis of nanoparticle anti-inflammatory and immunosuppressive properties, novel ways of protecting therapeutic nanoparticles from the immune recognition, as well as case studies regarding nanoparticle sterilization, complement activation, protein binding and immunotherapy of cancer. The second edition comes in 3 volumes. Volume 1 is focused on nanoparticle characterization, sterility and sterilization, pyrogen contamination and depyrigenation. It also contains overview of regulatory guidelines, protocols for in vitro and in vivo immunotoxicity studies, and correlation between in vitro and in vivo immunoassays. Volume 2 is focused on hematocompatibility of nanomaterials. It provides comprehensive review and protocols for investigating nanoparticle interaction with erythrocytes, platelets, endothelial cells, plasma coagulation factors and plasma proteins forming so called 'corona' around nanoparticles. Volume 3 is dedicated to nanoparticle interaction with and effects on the immune cell function. It also contains examples of nanoparticle use for delivery of antiviral and anti-inflammatory drugs.

Download or read book Handbook Of Immunological Properties Of Engineered Nanomaterials Second Edition In 3 Volumes written by Dobrovolskaia Marina A and published by World Scientific. This book was released on 2016-01-28 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides comprehensive overview of the field of immunology related to engineered nanomaterials used for biomedical applications. It contains literature review, case studies and protocols. The book can serve as a source of information about nanoimmunotoxicology for both junior scientists and experts in the field. The authors have more than 10 years of experience with preclinical characterization of engineered nanomaterials used for medical applications, and they share their experience with the readers. In addition, the international team of experts in the field provides the opinion and share the expertise on individual topics related to nanoparticle physicochemical characterization, hematocompatibility, and effects on the immune cell function . The second edition contains updated chapters from the first edition plus new chapters covering areas of tumor immunology, nanoparticle interaction with lymphatic system, mathematical modeling of protein corona, utilization of nanoparticles for the delivery of antiviral drugs, extensive analysis of nanoparticle anti-inflammatory and immunosuppressive properties, novel ways of protecting therapeutic nanoparticles from the immune recognition, as well as case studies regarding nanoparticle sterilization, complement activation, protein binding and immunotherapy of cancer. The second edition comes in 3 volumes. Volume 1 is focused on nanoparticle characterization, sterility and sterilization, pyrogen contamination and depyrigenation. It also contains overview of regulatory guidelines, protocols for in vitro and in vivo immunotoxicity studies, and correlation between in vitro and in vivo immunoassays. Volume 2 is focused on hematocompatibility of nanomaterials. It provides comprehensive review and protocols for investigating nanoparticle interaction with erythrocytes, platelets, endothelial cells, plasma coagulation factors and plasma proteins forming so called 'corona' around nanoparticles. Volume 3 is dedicated to nanoparticle interaction with and effects on the immune cell function. It also contains examples of nanoparticle use for delivery of antiviral and anti-inflammatory drugs.

Download or read book Nanotoxicology in Humans and the Environment written by Jamie R. Lead and published by Springer Nature. This book was released on 2021-12-13 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the area of ‘Nanotoxicology’ but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely.

Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Marina Dobrovolskaia and published by World Scientific. This book was released on 2013 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Download or read book Tissue Engineering And Nanotheranostics written by Shi Donglu and published by World Scientific. This book was released on 2017-10-27 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine. An important aspect of this book is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer, therefore breaking barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnoses and therapies capable of tackling major clinical issues."--Publisher's website.

Download or read book Cancer Therapeutics And Imaging Molecular And Cellular Engineering And Nanobiomedicine written by Rege Kaushal and published by World Scientific. This book was released on 2017-12-05 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the latest advancements in molecular and cellular engineering approaches in addition to nanotechnology for cancer therapeutics and imaging. It also provides an excellent background and state-of-the-art developments in the fields of drug and gene delivery, engineering nanoparticles for therapy and diagnostics, and cancer imaging techniques. The contents of this book include chapters on cutting-edge science in molecular and cellular engineering and nanotechnology as applied to therapeutics and imaging in cancer diseases. The chapters also provide a comprehensive overview on gene therapy and delivery methods for cancer treatment, oral drug delivery and barriers, cancer imaging for diagnostics and therapy, and the latest developments in these fields. Contents: Optically Modulated Theranostic Nanoparticles (Niksa Valim & Amit Joshi)Gene Therapy Treatments for Cancer (Jacob Elmer)Nanocarrier based Pulmonary Gene Delivery for Lung Cancer: Therapeutic and Imaging Approaches (Nishant S Gandhi, Micah Glasgow & Mahavir B Chougule)Quantitative Contrast Enhanced Ultrasound Imaging in Cancer Therapy (Shashank R Sirsi & Mark A Borden)Multifunctional Dendritic Nanoparticles as a Nanomedicine Platform (Hao-jui Hsu, Ryan M Pearson & Seungpyo Hong)Oral Drug Delivery Systems for Gastrointestinal Cancer Therapy (Yue-Wern Huang & Sutapa Barua)Cancer Therapeutics with Light: Role of Nanoscale and Tissue Engineering in Photodynamic Therapy (Joyce Liu, Huang-Chiao Huang, Emma Briars, Girgis Obaid, Imran Rizvi & Tayyaba Hasan)Targeted Contrast Agents for 1H MRI of Tumor Microenvironment (Shubhangi Agarwal & Vikram D Kodibagkar)Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Anti-Cancer Delivery Systems for Therapy and Diagnostics (Samuel V Mussi & Vladimir P Torchilin) Readership: Students and researchers in nanobiotechnology, nanomedicine, cancer research, bioengineering and medical imaging. Keywords: Nanobiotechnology;Nanomedicine;Nanoparticles;Cancer Research;Cancer Therapy;Gene Therapy;Bioengineering;Medical ImagingReview: Key Features: Novel aspects in cancer therapeutic delivery, comprehensive molecular and cellular aspects of cancer delivery and imaging, latest advanced in nanotechnology for cancer

Download or read book Silver Nanoparticles written by Khan Maaz and published by . This book was released on 2018-07 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Translational Nanomedicine written by Robert A. Meyers and published by Wiley-Blackwell. This book was released on 2020-03-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics.

Download or read book Characterization of Nanoparticles Intended for Drug Delivery written by and published by Springer. This book was released on 2011-08-14 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immune Aspects of Biopharmaceuticals and Nanomedicines written by Raj Bawa and published by CRC Press. This book was released on 2019-01-10 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in the immunologic aspects of biotherapeutics and nanomedicines in the past two decades has necessitated an authoritative and comprehensive reference source that can be relied upon by immunologists, biomedical researchers, clinicians, pharmaceutical companies, regulators, venture capitalists, and policy makers alike. This text provides a thorough understanding of immunology, therapeutic potential, clinical applications, adverse reactions, and approaches to overcoming immunotoxicity of biotherapeutics and nanomedicines. It also tackles critical, yet often overlooked topics such as immune aspects of nano-bio interactions, current FDA regulatory guidances, complement activation-related pseudoallergy (CARPA), advances in nanovaccines, and immunogenicity testing of protein therapeutics.

Download or read book Unraveling the Safety Profile of Nanoscale Particles and Materials written by Andreia Ferreira de Castro Gomes and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.

Download or read book NanoparticleProtein Corona written by Ashutosh Kumar and published by Royal Society of Chemistry. This book was released on 2019-07-26 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.

Download or read book Biological Responses to Nanoscale Particles written by Peter Gehr and published by Springer. This book was released on 2019-04-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Download or read book Genotoxicity Assessment written by Alok Dhawan and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetic toxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences.

Download or read book Handbook of Nanomaterials for Cancer Theranostics written by Joao Conde and published by Elsevier. This book was released on 2018-06-27 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Download or read book Delivering Nucleic Acids to Immune and Non Immune Cells written by Francesca Re and published by Frontiers Media SA. This book was released on 2024-02-16 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.