Download or read book Towards Precision Medicine in Vasculitis written by Federico Alberici and published by Frontiers Media SA. This book was released on 2021-01-05 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anti Neutrophil Cytoplasmic Antibody ANCA Associated Vasculitis written by Renato Alberto Sinico and published by Springer Nature. This book was released on 2019-09-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome). This volume will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these diseases.
Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine
Download or read book Immunomodulatory Approaches in Cardiovascular Diseases written by Fouad Antoine Zouein and published by Frontiers Media SA. This book was released on 2022-04-25 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Treatment of Glomerulonephritis written by C.D. Pusey and published by Springer Science & Business Media. This book was released on 2007-05-28 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glomerulonephritis is one of the commonest causes of end-stage renal failure worldwide. Although there have been considerable advances in the management of renal failure by dialysis and transplantation, there has been relatively little progress in its prevention. This volume sets out to review current practice in the treatment of glomerulonephritis, which is aimed both at controlling the clinical manifestations, e.g. nephrotic syndrome, and at preventing the progression to renal failure. The term glomerulonephritis covers a wide range of conditions with different immunological, histological and clinical features. This volume therefore starts with reviews of the immunology and pathology of different types of glomerulonephritis. This is followed by detailed consideration of the treatment of the commoner primary and secondary forms of the disease. There are separate chapters on special circumstances, such as glomerulonephritis in pregnancy or following renal transplantation. In each chapter, attempts are made to review the evidence for the effectiveness of treatment, based on controlled trials, immunopathological principles and the authors' considerable experience. Although some aspects of the treatment of glomerulonephritis can be found in the standard texts on renal disease, this volume provides an up-to-date, thoroughly referenced, and practical guide to management. As such, it should be of value to nephrologists and general physicians, including those in training, and to postgraduate students of nephrology.
Download or read book Vasculitis in Clinical Practice written by Richard A. Watts and published by Springer. This book was released on 2015-05-26 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on clinical presentation, diagnostic processes and current management of systematic vasculitis, and for this second edition the Editors have updated the treatment approach and nomenclature in line with current practice. Systemic vasculitides are a group of disorders which are of increasing importance. Many of these conditions are only rarely encountered by general physicians and often present significant diagnostic challenges. The Editors aim to provide easily accessible information in a pocket sized format. In doing so they hope to help both the generalist but also rheumatologists who only encounter these problems occasionally.
Download or read book Precision Medicine and Immuno Mediated Inflammatory Diseases Latest Progress and Next Challenges written by Luca Antonioli and published by Frontiers Media SA. This book was released on 2022-03-09 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Steroid Responsive Encephalopathy written by Xin Tian and published by Frontiers Media SA. This book was released on 2020-10-08 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Polymyalgia Rheumatica and Giant Cell Arteritis written by Jozef Rovensky and published by Springer Science & Business Media. This book was released on 2010-05-06 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present monograph, we offer current insights into polymyalgia rheumatica and giant cell arthritis. Both diseases are typical for advanced age, and their incidences increase with aging. Both diseases are a center point of interest not only for rheu- tologists, gerontologists, ophthalmologists or neurologists, but also for general prac- tioners. Early diagnosis and rapid treatment, mainly with glucocorticoids can save one of the most precious senses-vision. Damage to other organs (heart, aorta, co- nary arteries, liver, lungs, kidneys), which are supplied by the arteries affected by ischemic syndrome in the setting of giant cell arthritis, has serious consequences as well. Late diagnosis of giant cell arthritis can have fatal consequences for affected patients. It is a matter of fact that the human population is aging. Therefore, more attention has to be paid not only to diagnosis, clinical course and treatment of rheumatic d- eases in elderly, but also to their genetic, immunologic, endocrinologic, chronobiologic mechanisms, and state-of-the-art diagnostic modalities. I am convinced that the int- disciplinary research of the diseases will allow us to diagnose and treat the rheumatic diseases even faster and more effectively in the future.
Download or read book European Handbook of Dermatological Treatments written by Andreas D. Katsambas and published by Springer Nature. This book was released on 2023-11-06 with total page 1780 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely updated 4th edition retains the easy-to-use handbook format of the previous successful book, while fulfilling the need for a review of the content. Taking into consideration recent advances in systemic and topical treatments, state-of-the-art lasers, and the latest evidence-based recommendations, it now includes biologic agents for psoriasis and their use as off-label treatments in other skin disorders, targeted agents for malignant melanoma and basal cell carcinoma, and new treatment modalities for rosacea, acne, atopic dermatitis, and urticaria, to name but a few. The European Handbook of Dermatological Treatments provides concise, up-to-date overviews of treatment guidelines and clinical pearls for a large number of skin diseases. It is divided into three main sections addressing the many different skin diseases, the drugs available for dermatological treatments, and the various methods applied in dermatology, including fillers, botulinum toxin, lasers, dermoscopy, cryosurgery, and electrosurgery. Written by a recognized expert in the field, each chapter focuses on a particular skin disease, illustrating current treatments while providing a brief synopsis of the etiology and clinical presentation of the disease. Treatment indications and contraindications, modes of action, and dosages are clearly identified and the content is enhanced by a wealth of clinical pictures and tables, making it an engaging tool for professionals, and a valuable learning resource for young practitioners, as well as postgraduate students and residents.
Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.
Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Advances in Imaging written by Sikandar Shaikh and published by Springer Nature. This book was released on 2022-02-28 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the advances in the imaging and elaborates on their applications and advantages. It provides step by step overview of the various advanced imaging modalities like molecular imaging, nano imaging, robotic imaging, stem cell imaging, optical imaging, immunoimaging, etc. It describes the applications of various advanced imaging modalities in pathologies like oncology, infection and inflammation and other conditions and provides the available therapeutic options with the help of these modalities. It also covers the detailed aspects of various modalities like ultrasound, CT, MRI, PET-CT, PET-MRI and other modalities. It includes the detailed explanation of various radiotracers, biomarkers and probes with many applications. Chapters cover detailed information at molecular level. The book is helpful for oncologists, hematologists, surgeons and many other specialists.
Download or read book Precision Medicine in Chronic Inflammation written by and published by Frontiers Media SA. This book was released on 2021-11-09 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vasculitis An Issue of Neuroimaging Clinics of North America E Book written by Mahmud Mossa-Basha and published by Elsevier Health Sciences. This book was released on 2023-11-15 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Neuroimaging Clinics, guest editors Drs. Mahmud Mossa-Basha, Carlos Zamora, and Mauricio Castillo bring their considerable expertise to the topic of Vasculitis. Both conventional and advanced imaging play a central role in the diagnosis of vasculitides, and in this issue, top experts in the field discuss classification, guidelines, diagnosis, pathology, and imaging of every major type of vasculitis. - Contains 14 relevant, practice-oriented topics including classification and guidelines for diagnosis of vasculitis; clinical diagnosis, manifestations and treatment of infectious and post-infectious vasculopathies; usefulness of different imaging methods in the diagnosis of cerebral vasculopathy; imaging of vasculitis associated with systemic disease (RA, lupus, sarcoid); and more. - Provides in-depth clinical reviews on vasculitis, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Download or read book Handbook of Statistical Methods for Precision Medicine written by Eric Laber and published by CRC Press. This book was released on 2024-10-23 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistical study and development of analytic methodology for individualization of treatments is no longer in its infancy. Many methods of study design, estimation, and inference exist, and the tools available to the analyst are ever growing. This handbook introduces the foundations of modern statistical approaches to precision medicine, bridging key ideas to active lines of current research in precision medicine. The contributions in this handbook vary in their level of assumed statistical knowledge; all contributions are accessible to a wide readership of statisticians and computer scientists including graduate students and new researchers in the area. Many contributions, particularly those that are more comprehensive reviews, are suitable for epidemiologists and clinical researchers with some statistical training. The handbook is split into three sections: Study Design for Precision Medicine, Estimation of Optimal Treatment Strategies, and Precision Medicine in High Dimensions. The first focuses on designed experiments, in many instances, building and extending on the notion of sequential multiple assignment randomized trials. Dose finding and simulation-based designs using agent-based modelling are also featured. The second section contains both introductory contributions and more advanced methods, suitable for estimating optimal adaptive treatment strategies from a variety of data sources including non-experimental (observational) studies. The final section turns to estimation in the many-covariate setting, providing approaches suitable to the challenges posed by electronic health records, wearable devices, or any other settings where the number of possible variables (whether confounders, tailoring variables, or other) is high. Together, these three sections bring together some of the foremost leaders in the field of precision medicine, offering new insights and ideas as this field moves towards its third decade.
Download or read book Precision Medicine in Stroke written by Ana Catarina Fonseca and published by Springer Nature. This book was released on 2021-05-04 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.
