Download or read book Supercomplexity in Interaction written by Victoria Orange and published by Springer Nature. This book was released on 2019-11-08 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to explore the supercomplexity of interaction and to suggest ways of teaching about this supercomplexity in various settings, including intercultural communication and language-learning. Using complex systems theory, the author argues that interaction is actually a supercomplex adaptive system which interconnects a number of different complex systems (the 4Es: Expression, Encounter, Education, Emotion) to give it meaning. She then draws on the concept of heartfulness to promote different ways of understanding and teaching the supercomplexity of interaction. This book will be of interest to language educators and students, as well as scholars of intercultural communication.
Download or read book Cytochrome Complexes Evolution Structures Energy Transduction and Signaling written by William A. Cramer and published by Springer. This book was released on 2016-06-14 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction that describes the origin of cytochrome notation also connects to the history of the field, focusing on research in England in the pre-World War II era. The start of the modern era of studies on structure-function of cytochromes and energy-transducing membrane proteins was marked by the 1988 Nobel Prize in Chemistry, given to J. Deisenhofer, H. Michel, and R. Huber for determination of the crystal structure of the bacterial photosynthetic reaction center. An ab initio logic of presentation in the book discusses the evolution of cytochromes and hemes, followed by theoretical perspectives on electron transfer in proteins and specifically in cytochromes. There is an extensive description of the molecular structures of cytochromes and cytochrome complexes from eukaryotic and prokaryotic sources, bacterial, plant and animal. The presentation of atomic structure information has a major role in these discussions, and makes an important contribution to the broad field of membrane protein structure-function.
Download or read book Macromolecular Protein Complexes II Structure and Function written by J. Robin Harris and published by Springer Nature. This book was released on 2020-01-14 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Download or read book Mitochondrial Oxidative Phosphorylation written by Bernhard Kadenbach and published by Springer Science & Business Media. This book was released on 2012-06-23 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.
Download or read book A Structural Perspective on Respiratory Complex I written by Leonid Sazanov and published by Springer Science & Business Media. This book was released on 2012-05-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.
Download or read book Understanding Learning at Work written by David Boud and published by Routledge. This book was released on 2012-10-12 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Work now invariably requires a continual focus on learning: to improve productivity, to enhance the flexibility of employees and to develop and transform organizations. This volume brings together leading experts from the United States, Britain, Australia and New Zealand to critically evaluate the current debates on workplace learning and to propose directions for future developments in both research and practice. Topics covered include: * expectations of learning at work into the twenty-first century * learning theories, practice and performance implications * the relationship between workplace learning and other forms of lifelong learning * the international developments in competency-based approaches to learning and assessment * the influence of language, power, culture and gender upon the 'construction' of learning. Topical and informative, this volume will be an invaluable resource for students and researchers of training, HRD, continuing and adult education.
Download or read book Supporting Lifelong Learning Organising learning written by Roger Harrison and published by Psychology Press. This book was released on 2002 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at what types of learning environments promote lifelong learning, how they can be organized to support meaningful learning and what the implications of these shifts are for managers.
Download or read book Emerging Methods and Paradigms in Scholarship and Education Research written by Ling, Lorraine and published by IGI Global. This book was released on 2019-08-30 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a renaissance in the use of the term “scholarship,” as it is being used to define areas of academic endeavour, describe academic work and achievements, and measure the quality of higher education. Although all academicians are required to engage in scholarship, it is difficult to navigate as there is a misunderstanding of this concept as new methods and approaches emerge. Emerging Methods and Paradigms in Scholarship and Education Research is an essential academic book that is designed to explain the areas of scholarship and their contemporary relationship to key components of academic work: research, teaching, service, and engagement. The chapter authors explore conceptions of scholarship, paradigms, and methods that fit a variety of contexts and needs. Highlighting a wide range of approaches from scientific realism and neo-positivism to interpretative, transformative, and pragmatic educational strategies and policy, this book is ideal for researchers, teachers, educational leaders, academicians, educational policymakers, and quality assurance agencies.
Download or read book Computational Prediction of Protein Complexes from Protein Interaction Networks written by Sriganesh Srihari and published by Morgan & Claypool. This book was released on 2017-05-30 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complexes of physically interacting proteins constitute fundamental functional units that drive almost all biological processes within cells. A faithful reconstruction of the entire set of protein complexes (the "complexosome") is therefore important not only to understand the composition of complexes but also the higher level functional organization within cells. Advances over the last several years, particularly through the use of high-throughput proteomics techniques, have made it possible to map substantial fractions of protein interactions (the "interactomes") from model organisms including Arabidopsis thaliana (a flowering plant), Caenorhabditis elegans (a nematode), Drosophila melanogaster (fruit fly), and Saccharomyces cerevisiae (budding yeast). These interaction datasets have enabled systematic inquiry into the identification and study of protein complexes from organisms. Computational methods have played a significant role in this context, by contributing accurate, efficient, and exhaustive ways to analyze the enormous amounts of data. These methods have helped to compensate for some of the limitations in experimental datasets including the presence of biological and technical noise and the relative paucity of credible interactions. In this book, we systematically walk through computational methods devised to date (approximately between 2000 and 2016) for identifying protein complexes from the network of protein interactions (the protein-protein interaction (PPI) network). We present a detailed taxonomy of these methods, and comprehensively evaluate them for protein complex identification across a variety of scenarios including the absence of many true interactions and the presence of false-positive interactions (noise) in PPI networks. Based on this evaluation, we highlight challenges faced by the methods, for instance in identifying sparse, sub-, or small complexes and in discerning overlapping complexes, and reveal how a combination of strategies is necessary to accurately reconstruct the entire complexosome.
Download or read book Lipids in Health and Disease written by Peter Quinn and published by Springer Science & Business Media. This book was released on 2008-08-27 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Download or read book Realizing The University written by Barnett, Ronald and published by McGraw-Hill Education (UK). This book was released on 1999-12-01 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The University has lost its way. The world needs the university more than ever but for new reasons. If we are to clarify its new role in the world, we need to find a new vocabulary and a new sense of purpose. This book offers nothing less than a fundamental reworking of the way in which we understand the modern university.
Download or read book Higher Education Re formed written by Peter Scott and published by Routledge. This book was released on 2005-08-18 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specially commissioned contributions edited by some of the most respected academics currently working in the field of higher education, drawing the situation as it is now and looking forward to the developments of the coming years. It asks questions such as will 'Dearing' prove to be little more than a stop-gap? What will be the balance of power between education institutions, the state and the private sector? What are the realities behind 'lifelong learning', and what form will it take if it steps out of the realms of theory?
Download or read book The Dynamic Nature of Mitochondria written by Andreas S. Reichert and published by CRC Press. This book was released on 2024-04-15 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases. The following sections give an updated view on mitochondria: Mitochondrial ultrastructure: molecular mechanisms shaping the inner membrane Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay Mitochondrial control of cellular homeostasis: from redox signalling to interorganellar contact sites Mitochondria in health and disease: from mtDNA release to Complex I assembly Advanced methods in mitochondrial biology and metabolism research Integrative view on mitochondrial research and outlook The field of mitochondrial research has always been full of surprises and has helped science to advance tremendously. It developed hand in hand with landmark developments in technology, such as super-resolution microscopy (nanoscopy), and is currently influencing an increasing number of scientific disciplines. There is still much ‘new’ to find out about this ‘old’ organelle and I think that you can find interesting and also unexpected aspects of mitochondrial biology in this book. I hope the book will enhance your scientific curiosity and inspire your own research.
Download or read book Precision Molecular Pathology of Aggressive B Cell Lymphomas written by Genevieve M. Crane and published by Springer Nature. This book was released on with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Emerging Trends of Plant Physiology for Sustainable Crop Production written by Zafar Abbas, PhD. and published by CRC Press. This book was released on 2018-03-12 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant physiology is now considered as an essential ingredient for improving crop productivity, a continuing necessity with today’s ever-increasing world population. This new volume provides an understanding of the physiological basis of the various plant processes and their underlying mechanisms under fluctuating environments, which is of great importance for sustainable crop production. Further advances in cellular and molecular biology hold promise to modify physiological processes, thereby improving the quality and quantity of major food crops and ensuring stability in yield of the produce even under severe abiotic stress. This book covers the latest information on the physiological basis of plant productivity, including abiotic stress adaptation and management, plant nutrition, climate change and plant productivity, transgenic and functional genomics, and plant growth regulators and their applications. The chapters in this volume tackle some of these key issues of sustainable plant production and evolve future strategies in overcoming challenges faced by the agricultural sector as a whole. The topics covered in this book presents important from research reputed scientists. This volume is a rich source of information in one place. It will be a useful resource for researchers and extension workers involved in plant physiology and related disciplines. Key features: Provide the latest information on developments in plant physiology Covers abiotic and biotic stress on economically important crop species Presents a detailed collection of biotechnological approaches in plant physiology Covers plant growth regulators, secondary metabolites, germination, crop growth and development of different crop species Provides research from experts at internationally renowned institutes
Download or read book Photosynthesis written by Julian J. Eaton-Rye and published by Springer Science & Business Media. This book was released on 2011-11-04 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Photosynthesis: Plastid Biology, Energy Conversion and Carbon Assimilation” was conceived as a comprehensive treatment touching on most of the processes important for photosynthesis. Most of the chapters provide a broad coverage that, it is hoped, will be accessible to advanced undergraduates, graduate students, and researchers looking to broaden their knowledge of photosynthesis. For biologists, biochemists, and biophysicists, this volume will provide quick background understanding for the breadth of issues in photosynthesis that are important in research and instructional settings. This volume will be of interest to advanced undergraduates in plant biology, and plant biochemistry and to graduate students and instructors wanting a single reference volume on the latest understanding of the critical components of photosynthesis.
Download or read book Mitochondria in Health and Disease written by Paolo Bernardi and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial biology reinvented itself and became a new world that has attracted new scientists influencing every field of biomedical research. Mitochondrial research is growing and changing, as reflected by the exponential rise in the number of conferences covering mitochondrial biology and the role of mitochondria in diseases ranging from neurodegenerative diseases,metabolic diseases and genetic muscular dystrophies toimmunopathologies and cancer. As the awareness of the essential role of mitochondria in pathology rose, a demand for new approaches to measure mitochondrial function resulted in the robust development of new forms of microscopy and spectroscopy that opened windows into previously unknown aspects of mitochondrial biology. Two Conferences provided an outstanding representation of this state of affairs, the Gordon Research Conference Mitochondrial Dynamics and Signaling (Ventura, California March 17-22, 2019) and the FASEB Conference Mitochondrial Biogenesis and Dynamics in Health and Disease (Palm Springs, California May 19-24, 2019). These conferences well reflected the explosion of the field of mitochondrial communication within the cell, between cells and across organs, as well as the budding of a new field on the definition of individual mitochondria and the identification of subtypes with diverse structural features that may serve different specific functions. Through our participation in these meetings, we conceived the idea to cover some of these topics in the Research Topic “Mitochondria in Health and Disease” of Frontiers in Physiology - Mitochondrial Research Specialty Section. Fitting the tradition of Frontiers, our contributors have generated a platform incuding both solid data and new concepts, as radical and courageous as they can be. We are pleased with the outcome and we hope that our readers will share our enthusiasm.
