Download or read book Microscopy of the Heart written by Lars Kaestner and published by Springer. This book was released on 2018-12-07 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.
Download or read book Steding s and Vir gh s Scanning Electron Microscopy Atlas of the Developing Human Heart written by R.J. Oostra and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas comprises a complete and extensive exposure of the spatial and temporal aspects of human cardiac development as seen with scanning electron microscopy. Apart from serving as a unique overview on cardiac development in the human embryo, this atlas gives an updated morphological reference of cardiac embryology for topographic correlation and enables the projection of experimental results in animals to the human situation.
Download or read book Electron Microscopy of the Cardiovascular System written by Bruno Kisch and published by . This book was released on 1960 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Viragh s and Steding s Scanning Electron Microscopy Atlas of the Developing Human Heart written by R. J. Oostra and published by Birkhauser. This book was released on 2006-08-01 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Features: Quick reference guide, Includes almost 200 scanning electron microscopy pictures, All photographs are paired with drawings that carry the legends, Provides detailed descriptions of the relevant developmental events. Steding's and Viragh's Scanning Electron Microscopy Atlas of the Developing Human Heart comprises a complete and extensive exposure of the spatial and temporal aspects of human cardiac development as seen with scanning electron microscopy. Apart from serving as a unique overview of cardiac development in the human embryo, this atlas gives an updated morphological reference of cardiac embryology for topographic correlation and enables the projection of experimental results in animals to the human situation.
Download or read book Dynamic Imaging of Function and Morphogenesis in the Developing Heart written by Jungho Ohn and published by . This book was released on 2013 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congenital heart disease, the most common birth defect, occurs up to 5% of live births in humans. Understanding the relationship between morphology and function during development in the embryonic heart has important medical implications. Our studies focus on developing non-invasive heart imaging tools to observe the dynamics of morphogenesis while the heart is growing and functioning. Our approach consists in setting up a computer-driven automated microscope equipped with high-speed and sensitive cameras, implementing sample mounting protocols, and developing image reconstruction and analysis software. In order to improve the specificity with which structures can be imaged in the beating heart, we developed multi-modal microscopy by combining high-speed and multi-color sequences taken in brightfield and fluorescence microscopy, respectively. In an effort to improve axial resolution in conventional widefield microscopy, we implemented dynamic optical projection tomography. To quantify variability when characterizing heart function, we developed in vivo high-throughput microscopy. Finally, we carried out joint and quantitative studies of heart morphogenesis and functiogenesis by use of a novel imaging technique, burst time-lapse microscopy (BTLM). This allowed building time-lapses revealing the morphogenesis of the highly dynamic cardiac valve leaflets as they progressively prevent retrograde flow between cardiac chambers. This work provides new insights into cardiogenesis and should allow better understanding of normal and diseased development. We anticipate that the developed tools will be applicable for imaging a wide range of dynamic biological samples.
Download or read book Applications of Intravital Nonlinear Microscopy in Cardiovascular Research written by Jason S. Jones and published by . This book was released on 2018 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coordinated contraction of the heart allows for efficient pumping of blood to the body, supplying organs with oxygen necessary for metabolism. In heart disease, reduction of blood flow to heart muscle tissue can result in damage to the tissue over time. The adult heart, unlike other organs, has a limited capacity to recover from this damage causing the mechanical work the heart can perform to decline over time. While our ability to restore flow to the heart and mitigate abnormal electrically conducting tissue has improved over the last few decades, therapies which restore mechanical function improving cardiac output, through repair and healing of the cardiac muscle have not been realized in the clinic. Historic models used to study heart disease lack the ability to quantitative study the progression of individual cells within the living heart following an injury. Here I have taken some first steps in providing imaging methods and tools to allow the study of a more complete picture of heart disease in the context of the whole animal using multiphoton microscopy. I present methods for quantification of cellular resolved excitation and contraction, demonstrate the potential of THG as a label free signal to study the atherosclerotic plaque environment, and characterize some of the optical properties of the heart necessary to push the imaging depth accessible with current multiphoton technology.
Download or read book Cardiovascular Pathology written by L. Maximilian Buja and published by Academic Press. This book was released on 2015-11-11 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation
Download or read book Electron microscopy of heart muscle in acute coronary insufficiency written by Franz Büchner and published by . This book was released on 1968 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Non invasive Investigation of Cardiac Tissue Compartments and Components Using MR Microscopy written by Min Sig Hwang and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: ABSTRACT: The heart responds to the ever-changing demands that the whole body places on the cardiovascular system. This life-time pump expels the blood out by generating a forceful and efficient contraction. The homogeneous function is the orchestrated outcome of morphologic, electrophysiological, molecular constituents that exhibit prominent heterogeneity in the heart. Non-invasive imaging of anatomical structure of the whole heart has increasing demand for the understanding of its role to normal function and pathological development. Our hypothesis is that magnetic resonance imaging at high magnetic fields can distinguish different tissue compartments and cellular components in the mammalian heart and monitor their pathophysiological alterations, in-situ. In this thesis, we investigate non-invasively tissue compartments and cellular components comprising the rabbit heart using 17.6 T and 11.1 T magnets. The attenuation of MR diffusion signal intensity is used to reflect change in the tissue compartments. Magnetic resonance micro images contrasted by diffusion and transverse relaxation time of water molecules reveal anatomical features previously unavailable. Besides the myocardium, we visualize anatomical details of the cardiac conduction system from the bundle of His to terminal ramification of the Purkinje fibers in the ventricles using threedimensional high resolution MR imaging and microscopic high angular resolution diffusion imaging (MHARDI). Anatomical relationship of constituents in the ventricular muscular interseptum is explored. The combined investigative technique of microscopic threedimensional high resolution MRI and MHARDI is observed to be an effective method of monitoring morphological changes occurring in cardiac tissue with advancing age.
Download or read book Bioresorbable Scaffolds written by Yoshinobu Onuma and published by CRC Press. This book was released on 2017-10-02 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.
Download or read book Electron Microscopy in Human Medicine written by Jan Vincents Johannessen and published by . This book was released on 1980 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiac Development written by Margaret L. Kirby and published by Oxford University Press. This book was released on 2007-03-22 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.
Download or read book Pathology of Heart Disease in the Fetus Infant and Child written by Michael T. Ashworth and published by Cambridge University Press. This book was released on 2019-08-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.
Download or read book Electron Microscopic Histology of the Heart written by Bruno Kisch and published by . This book was released on 1951 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functional Cardiac Magnetic Resonance Microscopy written by Anja Christina Sophie Brau and published by . This book was released on 2003 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electron microscopy of chick heart myofibrillogenesis written by John Edward Rash and published by . This book was released on 1967 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ILAR News written by and published by . This book was released on 1972 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:
