Download or read book Interfacial Interactions Between Biomolecules and Materials written by Aracely Rocha-Zapata and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This research investigates the interfacial interactions between biological entities and synthetic materials at two length scales: bulk and nanometer size. At the bulk scale, biomolecule adhesion is key for synthetic material incorporation in the body. Quantifying the adhesion strength becomes necessary. For the nanometer scale, the nanoparticles are generally delivered through the blood stream and their effect on the blood flow must be studied. An experimental approach was taken to study interaction at both material length scales. The cell/protein adhesion strength to bulk-sized materials was studied. The goal was to identify the most influential factor affecting adhesion: chemistry or surface roughness. The effects of nanoparticles on the viscosity of protein and amino acid solutions were measured. A statistical thermodynamic analysis was focused on the entropy change induced by the addition of gold nanoparticles to protein/amino acid solutions. Rheological studies were applied. A rheometer with a parallel plate was used to quantify the adhesion strength of cells and proteins to synthetic surfaces at the bulk scale. The adhesion strength depends on the applied shear stress and the radius of cells or proteins that remained attached to the surface after testing. At the nanometer scale, the viscosity of the nanoparticle enhanced protein or amino acid solutions were measured with a cone and plate. The adhesion studies were conducted with the following biological entities: fibroblasts, egg-white protein, and neurons. The fibroblast adhesion to poly(carbonate) and poly(methyl methacrylate) demonstrate fibroblasts are strongly attached to highly polar materials. Protein adhesion to titanium and chromium nitride coatings showed that chemical composition is the most influential factor. The neuron adhesion to poly-D-lysine coated glass demonstrated that neuron strengthening was due to an increase in adhesion molecules at the neuron/material interface. For nanoparticulates, it was found that the charged nanoparticles affect the protein and amino acid conformation and the potential energy of the solutions. Quantifying biomolecule adhesion to surfaces and predicting the behavior of nanoparticles inside a biological system are crucial for material selection and application. The major impact of this research lies in observing the interaction mechanisms at the interfaces of material-biological entities.

Download or read book Nanomaterials and Their Interactive Behavior with Biomolecules Cells and Tissues written by Yogendrakumar H. Lahir and published by Bentham Science Publishers. This book was released on 2020-08-04 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscience is a multidisciplinary area of science which enables researchers to create tools that help in understanding the mechanisms related to the interactions between nanomaterials and biomolecules (nanotechnology). Nanomaterials represent nanotechnology products. These products have an enormous impact on technical industries and the quality of human life. Nanomaterials directly or indirectly have to interact with biosystems. It is, therefore, essential to understand the beneficial and harmful interactions of nanomaterials with and within a biosystem, especially with reference to humans. This book provides primary and advanced information concerning the interactions between nanomaterials and the components of a typical biosystem to readers. Chapters in the book cover, in a topic-based approach, the many facets of nanomolecular interactions with biological molecules and systems that influence their behavior, bioavailability and biocompatibility (including nucleic acids, cell membranes, tissues, enzymes and antibodies). A note on the applications of nanomaterials is also presented in the conclusion of the book to illustrate the usefulness of this class of materials. The contents of the book will benefit students, researchers, and technicians involved in the fields of biological sciences, such as cell biology, medicine, molecular biology, food technology, cosmetology, pharmacology, biotechnology, and environmental sciences. The book also provides information for the material science personnel, enabling them to understand the basics of target-oriented nanomaterials design for specific objectives.

Download or read book Interfacial Phenomena on Biological Membranes written by Manoranjan Arakha and published by Springer. This book was released on 2018-01-10 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on important interfacial phenomena, such as interfacial potential and interfacial multi-functionality, responsible for determining the fate of nanoparticles inside the biological milieu. Additionally, this book explores the role of surface defects in photocatalytic nanoparticles in defining the nanoparticle interaction to biological membrane and cytotoxic propensity.The authors describe the interfacial assembly of peptide/protein on conformational/functional dynamics of the peptide/protein, which may be adopted as an approach to moderate the protein misfolding diseases.

Download or read book Biological Interactions on Materials Surfaces written by David A. Puleo and published by Springer Science & Business Media. This book was released on 2009-06-26 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.

Download or read book Nanoscale Probes of the Solid Liquid Interface written by Andrew A. Gewirth and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale Probes of the Solid--Liquid Interface deals with the use of the scanning tunnelling microscope (STM) and related instrumentation to examine the phenomena occurring at the interface between solid and liquid. Scanning probe microscopy (the collective term for such instruments as the STM, the atomic force microscope and related instrumentation) allows detailed, real space atomic or lattice scale insight into surface structures, information which is ideally correlated with surface reactivity. The use of SPM methods is not restricted to ultrahigh vacuum: the STM and AFM have been used on samples immersed in solution or in ambient air, thus permitting a study of environmental effects on surfaces. At the solid--liquid interface the reactivity derives precisely from the presence of the solution and, in many cases, the application of an external potential. Topics covered in the present volume include: the advantages of studying the solid--liquid interface and the obtaining of additional information from probe measurements; interrelationships between probe tip, the interface and the tunnelling process; STM measurements on semiconductor surfaces; the scanning electrochemical microscope, AFM and the solid--liquid interface; surface X-ray scattering; cluster formation on graphite electrodes; Cu deposition on Au surfaces; macroscopic events following Cu deposition; deposition of small metallic clusters on carbon; overpotential deposition of metals; underpotential deposition; STM on nanoscale ceramic superlattices; reconstruction events on Au(ijk) surfaces; Au surface reconstructions; friction force measurements on graphite steps under potential control; and the biocompatibility of materials.

Download or read book Biomolecular Interfaces written by Ariel Fernández Stigliano and published by Springer. This book was released on 2015-04-20 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.

Download or read book Frontiers in Surface Science and Interface Science written by C.B. Duke and published by Gulf Professional Publishing. This book was released on 2002-05-21 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt: Any notion that surface science is all about semiconductors and coatings is laid to rest by this encyclopedic publication: Bioengineered interfaces in medicine, interstellar dust, DNA computation, conducting polymers, the surfaces of atomic nuclei - all are brought up to date. Frontiers in Surface and Interface Science - a milestone publication deserving a wide readership. It combines a sweeping expert survey of research today with an educated look into the future. It is a future that embraces surface phenomena on scales from the subatomic to the galactic, as well as traditional topics like semiconductor design, catalysis, and surface processing, modeling and characterization. And, great efforts have been made to express sophisticated ideas in an attractive and accessible way. Nanotechnology, surfaces for DNA computation, polymer-based electronics, soft surfaces, interstellar surface chemistry - all feature in this comprehensive collection.

Download or read book An Introduction to Tissue Biomaterial Interactions written by Kay C. Dee and published by John Wiley & Sons. This book was released on 2003-04-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.

Download or read book Quantifying Interactions of Biomolecules with Inorganic Surfaces written by Abhijeet Patra and published by Springer. This book was released on 2016-12-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis demonstrates the adaptation of existing techniques and principles towards enabling clean and precise measurements of biomolecules interacting with inorganic surfaces. In particular, it includes real-time measurement of serum proteins interacting with engineered nanomaterial. Making meaningful and unambiguous measurements has been an evolving problem in the field of biology and its various allied domains, primarily due to the complex nature of experiments and the large number of possible interferants. The subsequent quantification of interactions between biomolecules and inorganic surfaces solves pressing problems in the rapidly developing fields of lipidomics and nanomedicine.

Download or read book Dynamics of Advanced Sustainable Nanomaterials and Their Related Nanocomposites at the Bio Nano Interface written by Niranjan Karak and published by Elsevier. This book was released on 2019-07-30 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamics of Advanced Sustainable Nanomaterials and Their Related Nanocomposites at the Bio-Nano Interface highlights the most recent research findings (conducted over the last 5-6 years) on the dynamics of nanomaterials, including their multifaceted, advanced applications as sustainable materials. In addition, special attributes of these materials are discussed from a mechanistic and application point-of-view, including their sustainability and interfacial interactions at the bio-nano interface and different applications. This book presents an important reference resource on advanced sustainable nanomaterials for chemical, nano-, and materials technologists who are looking to learn more about advanced nanocomposites with sustainable attributes. Finally, the book examines the emerging market for sustainable materials and their advanced applications, with a particular focus on the bio-nano interface and their future outlook. Features detailed information on the fundamentals of bio-nano interfacial interactions in sustainable nanomaterials Includes advanced applications of these materials that will help the end user select the appropriate materials for their desired application Features extensive information on the dynamics of these materials, helping the end user extend their work into new applications

Download or read book Handbook of Neuroengineering written by Nitish V. Thakor and published by Springer Nature. This book was released on 2023-02-02 with total page 3686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook serves as an authoritative reference book in the field of Neuroengineering. Neuroengineering is a very exciting field that is rapidly getting established as core subject matter for research and education. The Neuroengineering field has also produced an impressive array of industry products and clinical applications. It also serves as a reference book for graduate students, research scholars and teachers. Selected sections or a compendium of chapters may be used as “reference book” for a one or two semester graduate course in Biomedical Engineering. Some academicians will construct a “textbook” out of selected sections or chapters. The Handbook is also meant as a state-of-the-art volume for researchers. Due to its comprehensive coverage, researchers in one field covered by a certain section of the Handbook would find other sections valuable sources of cross-reference for information and fertilization of interdisciplinary ideas. Industry researchers as well as clinicians using neurotechnologies will find the Handbook a single source for foundation and state-of-the-art applications in the field of Neuroengineering. Regulatory agencies, entrepreneurs, investors and legal experts can use the Handbook as a reference for their professional work as well.​

Download or read book Progress in Adhesion and Adhesives Volume 2 written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2017-06-15 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the ever-increasing amount of research being published it is a Herculean task to be fully conversant with the latest research developments in any field, and the arena of adhesion and adhesives is no exception. Thus, topical review articles provide an alternate and very efficient way to stay abreast of the state-of-the-art in may subjects representing the field of adhesion science and adheisves. Based on the success and the warm reception accorded to the premier volume in this series “Progress in Adhesion and Adhesives” (containing the review articles published in Volume 2 (2014) of the journal Reviews of Adhesion and Adhesives (RAA)), volume 2 comprises 14 review articles published in Volume 4 (2016) of RAA. The subjects of these 14 reviews fall into the following general areas: 1. Surface modification of polymers for a variety of purposes. 2. Adhesion aspects in reinforced composites 3. Thin films/coatings and their adhesion measurement 4. Bioadhesion and bio-implants 5. Adhesives and adhesive joints 6. General adhesion aspects The topics covered include: surface modification of natural fibers for reinforced polymer composites; adhesion of submicrometer thin metals films; surface treatments to modulate bioadhesion; hot-melt adhesives from renewable resources; particulate-polymer composites; functionally graded adhesively bonded joints; fabrication of nano-biodevices; effects of particulates on contact angles , thermal stresses in adhesively bonded joints and ways to mitigate these; laser-assisted electroless metallization of polymer materials; adhesion measurement of coatings on biodevices/implants; cyanoacrylate adhesives; and adhesion of green flame retardant coatings onto polyolefins.

Download or read book Spectroscopy and Dynamics of Single Molecules written by and published by Elsevier. This book was released on 2019-08-14 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy and Dynamics of Single Molecules: Methods and Applications reviews the most recent developments in spectroscopic methods and applications. Spectroscopic techniques are the chief experimental methods for testing theoretical models and research in this area plays an important role in stimulating new theoretical developments in physical chemistry. This book provides an authoritative insight into the latest advances in the field, highlighting new techniques, current applications, and potential future developments An ideal reference for chemists and physicists alike, Spectroscopy and Dynamics of Single Molecules: Methods and Applications is a useful guide for all those working in the research, design, or application of spectroscopic tools and techniques across a wide range of fields. Includes the latest research on ultrafast vibrational and electronic dynamics, nonlinear spectroscopies, and single-molecule methods Makes the content accessible to researchers in chemistry, biophysics, and chemical physics through a rigorous multi-disciplinary approach Provides content edited by a world-renowned chemist with more than 30 years of experience in research and instruction

Download or read book Nanoparticle Technology Handbook written by Toyokazu Yokoyama and published by Elsevier. This book was released on 2012-04-13 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook explains aspects of nanoparticles with many application examples showing their advantages and advanced development.

Download or read book Switchable and Responsive Surfaces and Materials for Biomedical Applications written by Johnathan Zhang and published by Elsevier. This book was released on 2014-12-11 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors. A comprehensive overview of switchable and responsive materials and surfaces Includes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfaces Detailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices

Download or read book Cell and Material Interface written by Nihal Engin Vrana and published by CRC Press. This book was released on 2018-09-03 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro. Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering.

Download or read book Hybrid Polymer Composite Materials written by Vijay Kumar Thakur and published by Woodhead Publishing. This book was released on 2017-06-03 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hybrid Polymer Composite Materials: Properties and Characterisation presents the latest on these composite materials that can best be described as materials that are comprised of synthetic polymers and biological/inorganic/organic derived constituents. The combination of unique properties that emerge as a consequence of the particular arrangement and interactions between the different constituents provides immense opportunities for advanced material technologies. This series of four volumes brings an interdisciplinary effort to accomplish a more detailed understanding of the interplay between synthesis, structure, characterization, processing, applications, and performance of these advanced materials, with this volume focusing on their properties and characterization. Provides a clear understanding of the present state-of-the-art and the growing utility of hybrid polymer composite materials Includes contributions from world renowned experts and discusses the combination of different kinds of materials procured from diverse resources Discusses their synthesis, chemistry, processing, fundamental properties, and applications Provides insights on the potential of hybrid polymer composite materials for advanced applications