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Book Benzimidazole

    Book Details:
  • Author : Aksel A. Vestergaard
  • Publisher :
  • Release : 2020
  • ISBN : 9781536169867
  • Pages : 0 pages

Download or read book Benzimidazole written by Aksel A. Vestergaard and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Benzimidazole: Preparation and Applications first defines the structure, physical and chemical properties of the benzimidazole compound class. Further conventional and alternative synthesis methods and important reactions of these compound derivatives are illustrated with examples. The authors provide an overview of benzimidazole-based synthetic medicine and their significant applications in treating various ailments. The chemical reactions of benzimidazole with other heterocyclic compounds/chemical reagents produce a lot of new substituted molecules, which have potential pharmaceutical applications. A literature review is presented focusing on the synthesis of chiral compounds and their subsequent applications as therapeutic compounds in order to better evaluate the results so far. Additionally, the authors discuss how nenzimidazole derivatives play a vital role in organic light emitting diodes as emissive materials, host materials, electron transport materials, hole blocking materials, etc., and have pharmaceutical applications such as antimicrobial, antihypertensive, anti-HIV and anticancer. Following this, this collection examines classes of potential chemosensors possessing benzimidazole moieties which are capable of both visual and optical estimation of target analytes over a broad concentration range and without interference of contemporary analytes. Important methodologies used for the synthesis of variedly substituted benzimidazoles are presented along with their multi-target therapeutic uses. The latest research on anti-tumor and antimicrobial benzimidazole compounds, as well as structure-activity correlations, drug design, clinical and preclinical studies is also presented. Benzimidazole-based polymers with various architecture and copolymers are discussed with a variation of properties such as mechanical, thermal stability, thermo-oxidative stability and enhanced performance. The penultimate chapter covers a critical analysis of the recent developments in benzimidazole framework research and the future scope of benzimidazole framework in ligand designing. In closing, the synthesis and biological properties of coordination compounds containing benzimidazole derivatives are presented and discussed.

Book Imidazole and Benzimidazole Synthesis

Download or read book Imidazole and Benzimidazole Synthesis written by M. R. Grimmett and published by Academic Press. This book was released on 1997-06-02 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imidazole and Benzimidazole Synthesis is a comprehensive survey of the known methods of syntheses and ring modification. It brings together the multitude of synthesis of the imidazole ring in a systemic way interms of specific bond formation, and recommends the most attractive synthetic approaches. It also collects non-ring-synthetic approaches to classes of compounds such as nitro-, halogeno-, and amino-imidazoles, and covers the synthesis of N-substituted compounds and preparations of specific isomers. The only book in print dealing specifically with this topic Comprehensive survey of the known methods of synthesis and ring modification Recommends the most attractive synthetic approaches

Book Chemistry and Applications of Benzimidazole and its Derivatives

Download or read book Chemistry and Applications of Benzimidazole and its Derivatives written by Maria Marinescu and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.

Book Imidazole Based Drug Discovery

Download or read book Imidazole Based Drug Discovery written by Shikha Agarwal and published by Elsevier. This book was released on 2021-12-02 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives. This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry. Reviews the most current developments and future perspectives of imidazole on different disease therapies to achieve the ultimate goal of disease eradication Discusses the role of imidazole in contemporary science, technological innovation, drug development, critical challenges and future research directions Covers emerging trends on different eco-benign pathways to synthesize imidazole derivatives for the development of simpler synthetic protocols

Book Benzimidazole

    Book Details:
  • Author :
  • Publisher : BoD – Books on Demand
  • Release : 2022-07-13
  • ISBN : 1803551208
  • Pages : 164 pages

Download or read book Benzimidazole written by and published by BoD – Books on Demand. This book was released on 2022-07-13 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.

Book Chemistry and Applications of Benzimidazole and its Derivatives

Download or read book Chemistry and Applications of Benzimidazole and its Derivatives written by Maria Marinescu and published by . This book was released on 2019 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.

Book Progress in Heterocyclic Chemistry

Download or read book Progress in Heterocyclic Chemistry written by Vakhid A. Mamedov and published by Elsevier Inc. Chapters. This book was released on 2013-09-06 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the second part of this two-part review (for Part 1 see V.A. Mamedov, A. Nataliya, N.A. Zhukova, Prog. Heterocycl. Chem. 2012, 24, 55), recent advances in the synthesis of quinoxalines are reviewed. Syntheses that start from pyrazine fragments and from benzenoid units are discussed. The review covers quinoxaline synthesis starting from anilines and derivatives of anilines, from nitroarenes, from other heterocycles, including benzimidazoles, benzodiazepines, and from fragments that contain neither a pyrazine ring nor a benzene ring, for example, epoxides and azirines, pyrrolidin-3-ones and piperidin-3-ones, γ-butyrolactones, pyran-2,3-diones, and 4-hydroxythiazolidines, amongst others.

Book Supramolecular Chemistry of Anions

Download or read book Supramolecular Chemistry of Anions written by Antonio Bianchi and published by Wiley-VCH. This book was released on 1997-01-31 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the central role anionic species have been shown to play in both mineralogical and biological processes, until now there have been no comprehensive references dealing exclusively with anionic coordination chemistry. Written by a group comprising pioneering researchers from the United States and Europe, Supramolecular Chemistry of Anions covers all theoretical and practical aspects of anion complexation, from thermodynamics and structure to catalysis and various applications. The authors begin with the 1967 discovery of halide inclusion by bicyclic diammonium receptors and trace the development of anion coordination chemistry through the most recent developments in the field. Topics covered in detail include: * Pre-supramolecular anion chemistry * Natural and artificial molecules that can act as anion receptors * Preorganization and chemical design * Structural, thermodynamic, electrochemical, and photochemical aspects of anion coordination * Computer methods for receptor design and multiple host-guest relations * Anion receptor catalysis and molecular recognition and transformation of nucleotides Supramolecular Chemistry of Anions is a valuable professional resource for organic and inorganic chemists, analytical chemists, biotechnologists, pharmaceutical scientists, and environmental chemists. It also serves as an excellent graduate-level text for students of molecular recognition, catalysis, and biomimetic chemistry.

Book Organic Corrosion Inhibitors

Download or read book Organic Corrosion Inhibitors written by Chandrabhan Verma and published by John Wiley & Sons. This book was released on 2021-09-11 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of organic corrosion inhibitors used in modern industrial platforms, including current developments in the design of promising classes of organic corrosion inhibitors Corrosion is the cause of significant economic and safety-related problems that span across industries and applications, including production and processing operations, transportation and public utilities infrastructure, and oil and gas exploration. The use of organic corrosion inhibitors is a simple and cost-effective method for protecting processes, machinery, and materials while remaining environmentally acceptable. Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications provides up-to-date coverage of all aspects of organic corrosion inhibitors, including their fundamental characteristics, synthesis, characterization, inhibition mechanism, and industrial applications. Divided into five sections, the text first covers the basics of corrosion and prevention, experimental and computational testing, and the differences between organic and inorganic corrosion inhibitors. The next section describes various heterocyclic and non-heterocyclic corrosion inhibitors, followed by discussion of the corrosion inhibition characteristics of carbohydrates, amino acids, and other organic green corrosion inhibitors. The final two sections examine the corrosion inhibition properties of carbon nanotubes and graphene oxide, and review the application of natural and synthetic polymers as corrosion inhibitors. Featuring contributions by leading researchers and scientists from academia and industry, this authoritative volume: Discusses the latest developments and issues in the area of corrosion inhibition, including manufacturing challenges and new industrial applications Explores the development and implementation of environmentally-friendly alternatives to traditional toxic corrosion inhibitors Covers both established and emerging classes of corrosion inhibitors as well as future research directions Describes the anticorrosive mechanisms and effects of acyclic, cyclic, natural, and synthetic corrosion inhibitors Offering an interdisciplinary approach to the subject, Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications is essential reading for chemists, chemical engineers, researchers, industry professionals, and advanced students working in fields such as corrosion inhibitors, corrosion engineering, materials science, and applied chemistry.

Book Synthesis  Characterization and Biological Activities of Tridentate Ons Schiff Bases and Their Mixed ligand Metal Complexes Containing Imidazole Or Benzimidazole

Download or read book Synthesis Characterization and Biological Activities of Tridentate Ons Schiff Bases and Their Mixed ligand Metal Complexes Containing Imidazole Or Benzimidazole written by Nurul Ain Mazlan and published by . This book was released on 2014 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Contrast Agents III

    Book Details:
  • Author : Roger Alberto
  • Publisher : Springer Science & Business Media
  • Release : 2005-02-10
  • ISBN : 9783540225775
  • Pages : 252 pages

Download or read book Contrast Agents III written by Roger Alberto and published by Springer Science & Business Media. This book was released on 2005-02-10 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts

Book Studies Towards the Total Synthesis of Imidazole containing Natural Products

Download or read book Studies Towards the Total Synthesis of Imidazole containing Natural Products written by Lawton Anthony II Seal and published by . This book was released on 2019 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature has inspired man in all aspects of life, chemistry included. The first antibiotic ever discovered came from nature, and since then, chemists have been probing nature for insights to guide drug discovery and development. Alkaloids are a class of naturally occurring molecules which contain nitrogen atoms and can be found in all forms of life. Imidazole is common structural unit found in many natural molecules, from the simple amino acid histamine to more complex structures like the marine sponge derived alkaloid palau'amine. Many imidazole-containing natural products are biologically active, such as inhibiting the growth of tumors, possessing antibacterial properties, and influencing signaling pathways of cells like an inflammatory response. Access to large quantities of these molecules would aid medical science in drug discovery and design, potentially impacting the overall quality of life for all. It is therefore essential for the chemical community to pursue the synthesis of natural products not only to gain more knowledge in the overall science, allowing for better isolation,characterization, and synthesis of molecules, but also to better the quality of life and health as a whole.Chapter 1 of this dissertation describes the isolation and characterization of spiroleucettadine and terrazoanthines A-C. It further describes, in detail, the unsuccessful attempts to synthesis spiroleucettadine, which prompted its structural revision, and the only reported synthesis of the revised structure.Chapter 2 focuses on our approach to the total synthesis of spiroleucettadine. Initially our strategy centered on employing a novel reaction discovered in our lab to help facilitate the construction of the spirocyclic center. However, we later found this route to not be viable,leading to a significant revision in our strategy.In chapter 3 describe our approach to total synthesis of terrazoanthines A-C. Besides its purification and structural assignment,there are no reports pertaining to this molecule in the literature. Of the 3 molecules, only one of them possesses multiple stereochemical centers. However, upon further examination of the core structure we proposed a concise synthetic route leading to not only all 3 molecule, all possible stereoisomers through the construction of a key symmetric intermediate.In chapter 4 we discuss the oxidative chemistry of tetrahydrobenzimidazole. The two oxidants used were dimethyldioxarine and oxaziridine. The results show the choice of oxidant, N-protecting group,and the functionalization at the C2-position can greatly affect the outcome of the reactions, leading to additions, cyclizations, and ring openings.

Book Bioactive Heterocycles

Download or read book Bioactive Heterocycles written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book High Temperature Polymer Electrolyte Membrane Fuel Cells

Download or read book High Temperature Polymer Electrolyte Membrane Fuel Cells written by Qingfeng Li and published by Springer. This book was released on 2015-10-15 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of high-temperature polymer electrolyte membrane fuel cells (PEMFCs). PEMFCs are the preferred fuel cells for a variety of applications such as automobiles, cogeneration of heat and power units, emergency power and portable electronics. The first 5 chapters of the book describe rationalization and illustration of approaches to high temperature PEM systems. Chapters 6 - 13 are devoted to fabrication, optimization and characterization of phosphoric acid-doped polybenzimidazole membranes, the very first electrolyte system that has demonstrated the concept of and motivated extensive research activity in the field. The last 11 chapters summarize the state-of-the-art of technological development of high temperature-PEMFCs based on acid doped PBI membranes including catalysts, electrodes, MEAs, bipolar plates, modelling, stacking, diagnostics and applications.

Book Heterocyclic Compounds

Download or read book Heterocyclic Compounds written by Kristian Nylund and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.

Book Heterocyclic Organic Corrosion Inhibitors

Download or read book Heterocyclic Organic Corrosion Inhibitors written by Mumtaz A. Quraishi and published by Elsevier. This book was released on 2020-03-07 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic Organic Corrosion Inhibitors: Principles and Applications aims to comprehend the synthesis and application of organic heterocyclic compounds as corrosion inhibitors in various corrosive environments. Considering the high importance of corrosion inhibitor development for different industries, the book provides the fundamentals and most recent advancements in this field. The book is an indispensable reference tool for industrialists and academicians working in the field of corrosion protection. Provides a systematic overview of fundamentals and current advancements Acts as a primary reference for beginner researchers in this arena Presents a handy reference tool to different chemical industries Covers fundamentals, industrial applications and most recent advancements in this area