Download or read book Genetic Twists of Fate written by Stanley Fields and published by MIT Press. This book was released on 2013-02-08 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: How tiny variations in our personal DNA can determine how we look, how we behave, how we get sick, and how we get well. News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

Download or read book Twisting Fate written by Pamela Munster and published by The Experiment. This book was released on 2018-09-25 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a woman who’s made her living researching breast cancer—and who lived through it herself—a personal yet practical guide to the medical and emotional facets of this life-changing diagnosis A leading oncologist at the University of California San Francisco, Dr. Pamela Munster has advised thousands of women on how to cope with the realities of breast cancer, from diagnosis through treatment and recovery. But her world turned upside down when, at forty-eight years old and in otherwise perfect health, she got a call saying that her own mammogram showed “irregularities.” That single word thrust her into a wholly new role—as patient, and not only that of cancer but of the feared BRCA gene mutation as well. Suddenly, she realized that being a true “expert” in a disease was far beyond the scope of her medical training, and that she had a lot to learn if she wanted to hold onto her precious life. Weaving together her personal story with groundbreaking research on BRCA—responsible for breast cancer and many other inherited cancers affecting both women and men—Twisting Fate is an inspiring guide to living with the uncertainties of cancer. With authority, insight, and compassion, Dr. Munster uses her voice to create a safe space for genuine healing and honesty in a world otherwise too-often dominated by fear—and she is living proof of how important it is to embrace all the twists and turns of fate.

Download or read book Blueprint with a new afterword written by Robert Plomin and published by MIT Press. This book was released on 2019-07-16 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A top behavioral geneticist makes the case that DNA inherited from our parents at the moment of conception can predict our psychological strengths and weaknesses. In Blueprint, behavioral geneticist Robert Plomin describes how the DNA revolution has made DNA personal by giving us the power to predict our psychological strengths and weaknesses from birth. A century of genetic research shows that DNA differences inherited from our parents are the consistent lifelong sources of our psychological individuality—the blueprint that makes us who we are. Plomin reports that genetics explains more about the psychological differences among people than all other factors combined. Nature, not nurture, is what makes us who we are. Plomin explores the implications of these findings, drawing some provocative conclusions—among them that parenting styles don't really affect children's outcomes once genetics is taken into effect. This book offers readers a unique insider's view of the exciting synergies that came from combining genetics and psychology. The paperback edition has a new afterword by the author.

Download or read book Genomic Citizenship written by Ian McGonigle and published by MIT Press. This book was released on 2021-08-10 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: An anthropological study based on ethnographic work in Israel and Qatar explores the relationship between science, particularly genetics, and national identity. Based on ethnographic work in Israel and Qatar, two small Middle Eastern ethnonations with significant biomedical resources, Genomic Citizenship explores the relationship between science and identity. Ian McGonigle, originally trained as a biochemist, draws on anthropological theory, STS, intellectual history, critical theory, Middle Eastern studies, cultural studies, and critical legal studies. He connects biomedical research on ethnic populations to the political, economic, legal, and historical context of the state; to global trends in genetic medicine; and to the politics of identity in the context of global biomedical research. Genomic Citizenship is more an anthropology of scientific objects than an anthropology of scientists or an ethnography of the laboratory. McGonigle bases his untraditional project on traditional anthropological methods, including participant observation. Some of the most persuasive data in the book are from public records, legal and historical sources, published scientific papers, institutional reports, websites, and brochures. McGonigle discusses biological understandings of Jewishness, especially in relation to the intellectual history of Zionism and Jewish political thought, and considers the possibility of a novel application of genetics in assigning Israeli citizenship. He also describes developments in genetic medicine in Qatar and analyzes the Qatari Biobank in the context of Qatari nationalism and state-building projects. Considering possible consequences of findings on the diverse origins of the Qatari population for tribal identities, he argues that the nation cannot be defined as either a purely natural or biological entity. Rather, it is reified, reinscribed, and refracted through genomic research and discourse.

Download or read book Inequality written by Carles Lalueza-Fox and published by MIT Press. This book was released on 2022-02-08 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: How genomics reveals deep histories of inequality, going back many thousands of years. Inequality is an urgent global concern, with pundits, politicians, academics, and best-selling books all taking up its causes and consequences. In Inequality, Carles Lalueza-Fox offers an entirely new perspective on the subject, examining the genetic marks left by inequality on humans throughout history. Lalueza-Fox describes genetic studies, made possible by novel DNA sequencing technologies, that reveal layers of inequality in past societies, manifested in patterns of migration, social structures, and funerary practices. Through their DNA, ancient skeletons have much to tell us, yielding anonymous stories of inequality, bias, and suffering. Lalueza-Fox, a leader in paleogenomics, offers the deep history of inequality. He explores the ancestral shifts associated with migration and describes the gender bias unearthed in these migrations—the brutal sexual asymmetries, for example, between male European explorers and the women of Latin America that are revealed by DNA analysis. He considers social structures, and the evidence that high social standing was inherited—the ancient world was not a meritocracy. He untangles social and genetic factors to consider whether wealth is an advantage in reproduction, showing why we are more likely to be descended from a king than a peasant. And he explores the effects of ancient inequality on the human gene pool. Marshaling a range of evidence, Lalueza-Fox shows that understanding past inequalities is key to understanding present ones.

Download or read book The Next 500 Years written by Christopher E. Mason and published by MIT Press. This book was released on 2022-04-12 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: An argument that we have a moral duty to explore other planets and solar systems--because human life on Earth has an expiration date. Inevitably, life on Earth will come to an end, whether by climate disaster, cataclysmic war, or the death of the sun in a few billion years. To avoid extinction, we will have to find a new home planet, perhaps even a new solar system, to inhabit. In this provocative and fascinating book, Christopher Mason argues that we have a moral duty to do just that. As the only species aware that life on Earth has an expiration date, we have a responsibility to act as the shepherd of life-forms--not only for our species but for all species on which we depend and for those still to come (by accidental or designed evolution). Mason argues that the same capacity for ingenuity that has enabled us to build rockets and land on other planets can be applied to redesigning biology so that we can sustainably inhabit those planets. And he lays out a 500-year plan for undertaking the massively ambitious project of reengineering human genetics for life on other worlds. As they are today, our frail human bodies could never survive travel to another habitable planet. Mason describes the toll that long-term space travel took on astronaut Scott Kelly, who returned from a year on the International Space Station with changes to his blood, bones, and genes. Mason proposes a ten-phase, 500-year program that would engineer the genome so that humans can tolerate the extreme environments of outer space--with the ultimate goal of achieving human settlement of new solar systems. He lays out a roadmap of which solar systems to visit first, and merges biotechnology, philosophy, and genetics to offer an unparalleled vision of the universe to come.

Download or read book The Story Within written by Amy Boesky and published by JHU Press. This book was released on 2013-10-10 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A compelling collection of essays that address the experiences of many who have genetically based illnesses.” —Library Journal The contributors to The Story Within share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available. More broadly, they consider how genetic information shapes the ways we see ourselves, the world, and our actions within it. People affected by genetic disease respond to such choices in varied ways. These writers reflect that breadth of response, yet they share the desire to challenge a restricted sense of what “health” is or whose life has value. They write hoping to expand conversations about genetics and identity—to deepen debate and generate questions. They or their families are affected by Huntington’s disease, Alzheimer’s disease, cancer, genetic deafness or blindness, schizophrenia, cystic fibrosis, Tay-Sachs, hypertrophic cardiomyopathy, fragile X, or Fanconi anemia. All of their stories remind us that genetic health is complicated, dynamic, and above all, deeply personal. Contributors include: Misha Angrist, Amy Boesky, Kelly Cupo, Michael Downing, Clare Dunsford, Mara Faulkner, Christine Kehl O’Hagan, Charlie Pierce, Kate Preskenis, Emily Rapp, Jennifer Rosner, Joanna Rudnick, Anabel Stenzel, Isabel Stenzel Byrnes, Laurie Strongin, Patrick Tracey, Alice Wexler

Download or read book Mendel s Dwarf written by Simon Mawer and published by Other Press, LLC. This book was released on 2012-12-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like his great-great-great-uncle, geneticist Gregor Mendel, Dr. Benedict Lambert struggles to unlock the secrets of heredity and genetic determinism. However, Benedict's mission is particularly urgent and particularly personal, for he was born with achondroplasia--he's a dwarf. He's also a man desperate for love and acceptance, and when he finds both in Jean, a shy librarian, he stumbles upon an opportunity to correct the injustice of his own, at least to him, unlucky genes. Entertaining and tender, this witty and surprisingly erotic novel reveals the beauty and drama of scientific inquiry as it informs us of the simple passions against which even the most brilliant mind is rendered powerless.

Download or read book Fables and Futures written by George Estreich and published by MIT Press. This book was released on 2019-03-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.

Download or read book The Gene Deal written by Robin Jequier and published by Createspace Independent Publishing Platform. This book was released on 2018-07-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is 2001 and Capsella-Biotech, a genetic research firm operating in Berlin and New Jersey, has joined the international race to complete the first ever map of the human genome. Controlled by a disturbed Afghan war veteran Dr Alexander Grishin, the firm's unique research technology puts it ahead of the others. Ambitious financier Guy Shepherd is hired to invest in Capsella-Biotech, but he uncovers something sinister. He takes dangerous risks to prevent suspected abuse of genetic engineering, and rouses the anger of his boss as well as the brutal ministrations of the unstable Dr Grishin. When Guy's girlfriend goes missing in New York following the 9/11 attacks, can he discover her fate, settle his differences with her father and work out a plan to prevent wholesale catastrophe? With a psychic element added to the mix, this is a powerful tale of science, high finance and greed. www.robinjequier.com

Download or read book The Norma Gene written by M.E. Roufa and published by Bitingduck Press LLC. This book was released on 2015-08-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the world’s first completely illegal clone of America’s 16th President, Abe Finkelstein grew up with just one wish: to live his life just like anybody else. But when you’re a living ringer for one of the country’s best-loved historical figures, privacy is hard to come by—especially when your face is on money. Across town, Norma Greenberg, one of the world’s many Marilyn Monroe clones, is struggling with identity issues of a different sort. It’s not easy going through life as a copy of the beautiful Norma Jeane Baker! When Abe is taken away by government agents eager to discover the secrets of his illustrious ancestor, Norma could be Abe’s last hope of escape—or, thanks to her kleptomania, his worst chance of recapture. With only their wits, a cigarette lighter, a bottle of perfume, and the disembodied arm of Richard Nixon, can Abe and Norma make it back to safety and anonymity?

Download or read book Crimson Vengeance written by Sheri Lewis Wohl and published by Bold Strokes Books Inc. This book was released on 2011-04-01 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Love, desire, and secretsÑa trail littered with murder and the choice one vampire will have to make that will seal her fate or set her free... Spokane County Medical Examiner Riah Preston has a job to do and a secret to keep. Riah is a vampire and she's on a mission to discover a cure for the very thing that has kept her a prisoner of darkness for over five hundred years. With the help of Moses Lake Coroner Ivy Hernandez and genetic scientist Adriana James, they are on the verge of a breakthrough. When victims of a rogue vampire begin to show up along the I-90 corridor, things get complicated. The appearance of vampire hunter Colin Jamison complicates the situation even further. Will they be strong enough to stop this vampire killer cutting a wide path of death and destruction? Or will the secrets Riah holds in her heart destroy them all?

Download or read book Double Helix written by Eileen Merriman and published by Penguin Random House New Zealand Limited. This book was released on 2021-08-31 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Would you want to know what awaits you? Would you want to be in control of your life . . . and death? What would you do for love? 'Sooner or later, willingly or unwillingly, he’s going to leave you.' The words cut deep. Emily knows Jake is not like his father; he’d never leave her willingly. But if he has inherited his mother's genes, then Huntington’s disease is more than likely to take him away. He may even make the same request his mother made, when Jake was still a teenager: to end the suffering for good.

Download or read book Fool s Fate written by Robin Hobb and published by Spectra. This book was released on 2004-02-03 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Complex . . . an atmosphere-filled adventure . . . with a fair quota of surprises . . . a winning combination of strong characters and colorful societies.”—Kirkus Reviews In the final book in the Tawny Man Trilogy, Fitz and the Fool are tested more severely than ever in a book the Monroe News-Star calls “a breathtaking ride from beginning to end.” FitzChivalry Farseer has become firmly ensconced in the queen’s court. Along with his mentor, Chade, and the simpleminded yet strongly skilled Thick, Fitz strives to aid Prince Dutiful on a quest that could secure peace with the Out Islands—and win Dutiful the hand of the Narcheska Elliania. The Narcheska has set the prince an unfathomable task: to behead a dragon trapped in ice on the isle of Aslevjal. Yet not all the clans of the Out Islands support their effort. Are there darker forces at work behind Elliania’s demand? Knowing that the Fool has foretold he will die on the island of ice, Fitz plots to leave his dearest friend behind. But fate cannot so easily be defied.

Download or read book The Global Genome written by Eugene Thacker and published by MIT Press. This book was released on 2006-09-08 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: How global biotechnology is redefining "life itself." In the age of global biotechnology, DNA can exist as biological material in a test tube, as a sequence in a computer database, and as economically valuable information in a patent. In The Global Genome, Eugene Thacker asks us to consider the relationship of these three entities and argues that—by their existence and their interrelationships—they are fundamentally redefining the notion of biological life itself. Biological science and the biotech industry are increasingly organized at a global level, in large part because of the use of the Internet in exchanging biological data. International genome sequencing efforts, genomic databases, the development of World Intellectual Property policies, and the "borderless" business of biotech are all evidence of the global intersections of biology and informatics—of genetic codes and computer codes. Thacker points out the internal tension in the very concept of biotechnology: the products are more "tech" than "bio," but the technology itself is fully biological, composed of the biomaterial labor of genes, proteins, cells, and tissues. Is biotechnology a technology at all, he asks, or is it a notion of "life itself" that is inseparable from its use in the biotech industry? The three sections of the book cover the three primary activities of biotechnology today: the encoding of biological materials into digital form—as in bioinformatics and genomics; its recoding in various ways—including the "biocolonialism" of mapping genetically isolated ethnic populations and the newly pervasive concern over "biological security"; and its decoding back into biological materiality—as in tissue engineering and regenerative medicine. Thacker moves easily from science to philosophy to political economics, enlivening his account with ideas from such thinkers as Georges Bataille, Georges Canguilhem, Michel Foucault, Antonio Negri, and Paul Virilio. The "global genome," says Thacker, makes it impossible to consider biotechnology without the context of globalism.

Download or read book The Land written by Thomas Maltman and published by Soho Press. This book was released on 2020-10-13 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: A story of violence at the heart of a pastoral landscape, from the author of Indie Next pick and All Iowa Reads selection Little Wolves Recovering from a terrible auto accident just before the turn of the millennium, college dropout and hobbyist computer-game programmer Lucien Swenson becomes the caretaker of a house in northern Minnesota. Shortly after moving in, Lucien sets out to find a woman with whom he had an affair, who vanished along with money stolen from the bank where they had worked together. His search will take him to Rose of Sharon, a white supremacist church deep in the wilderness, where a cabal of outcasts awaits the end of the world at a place they call The Land. Lucien is visited at the house by a mysterious guest, who may not be who she claims, as well as a vast flock of violent ravens out of an apocalyptic vision. At once a mystery and spiritual noir, The Land explores the dark side of belief, entrenched white supremacy in the Heartland, the uniquely American obsession with end times, and the sacrifices we make for those we love.

Download or read book Klara and the Sun written by Kazuo Ishiguro and published by Vintage. This book was released on 2021-03-02 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • Once in a great while, a book comes along that changes our view of the world. This magnificent novel from the Nobel laureate and author of Never Let Me Go is “an intriguing take on how artificial intelligence might play a role in our futures ... a poignant meditation on love and loneliness” (The Associated Press). • A GOOD MORNING AMERICA Book Club Pick! Here is the story of Klara, an Artificial Friend with outstanding observational qualities, who, from her place in the store, watches carefully the behavior of those who come in to browse, and of those who pass on the street outside. She remains hopeful that a customer will soon choose her. Klara and the Sun is a thrilling book that offers a look at our changing world through the eyes of an unforgettable narrator, and one that explores the fundamental question: what does it mean to love?