Download or read book Fatty Acid Metabolism and Ketogenesis During a Streptococcus Pneumoniae Infection in the Rat written by Judith Gilligan Pace and published by . This book was released on 1980 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fatty Acid Metabolism and Ketogenesis in the Rat Exposed to Streptococcus Pneumoniae written by Judith G. Pace and published by . This book was released on 1980 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under the dual stress of infectious illness and starvation, the septic host's reduced ability to convert fatty acids to ketone bodies may be partly responsible for the protein-wasting state that accompanies the illness. Previous studies have shown that livers from rats infected with Streptococcus pneumoniae have a decreased ketogenic capacity compared to fasted controls. This study examines possible control sites of hepatic ketogenesis, including hepatic concentrations of coenzyme A, carnitine and malonyl-coenzyme A. These studies show that during pneumococcal sepsis, the decreased ketogenic capacity of the liver is accompanied by increased hepatic carnitine concentrations, especially acetylcarnitine, and decreased hepatic coenzyme A (CoA). Infection had no effect on muscle carnitine concentrations or hepatic malonyl-CoA content. These data demonstrate that the decreased rate of ketone body production during infection is not due to a carnitine deficiency. In contrast to malonyl-CoA's regulatory role in the fed and fasted state, the concentration of malonyl-CoA does not appear to be of major importance in determining the rate of ketogenesis during infection. The liver of the fasted-infected rat appears to be shuttling acetyl groups to carnitine, and fatty acyl-CoA away from oxidative pathways toward esterification.

Download or read book Hepatic Concentration and Distribution of Coenzyme A and Carnitine During a Streptococcus Pneumoniae Infection in the Rat Possible Implications on Fatty Acid Metabolism and Ketogenesis written by and published by . This book was released on 1981 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rats infected with Streptococcus pneumoniae were used to study the effect of pneumococcal infection on the hepatic concentrations and the subcellular distribution of carnitine and coenzyme A (CoA). Compared to fasted control rats, fasted-infected rats have a decreased ketogenic capacity that is associated with an accumulation of total hepatic carnitine and a decrease in total hepatic coenzyme A. The concentration of competing substrates (e.g., lactate and pyruvate) and nucleotide ratios (e.g., (Acetyl-CoA)/(CoA), (ATP)/ (ADP)(HPO4(2- )), and (NAD+)/(NADH)) are also variably affected by the infection. The concentrations of both lactate and pyruvate and the mitochondrial ratio of (NAD+)/(NADH) increased, while mitochondrial (acetyl-CoA)/(CoA) and the phosphorylation state or the (ATP)/(ADP)(HPO4(2- ) ratio decreased compared to fasted controls.

Download or read book Annual Progress Report written by and published by . This book was released on with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Progress Report written by U.S. Army Medical Research Institute of Infectious Diseases and published by . This book was released on 1980 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Progress Report U S Army Medical Research Institute of Infectious Diseases written by U.S. Army Medical Research Institute of Infectious Diseases and published by . This book was released on 1980 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Technical Abstract Bulletin written by and published by . This book was released on with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dissertation Abstracts International written by and published by . This book was released on 1981 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book American Doctoral Dissertations written by and published by . This book was released on 1980 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comprehensive Dissertation Index written by and published by . This book was released on 1984 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1973- include the following subject areas: Biological sciences, Agriculture, Chemistry, Environmental sciences, Health sciences, Engineering, Mathematics and statistics, Earth sciences, Physics, Education, Psychology, Sociology, Anthropology, History, Law & political science, Business & economics, Geography & regional planning, Language & literature, Fine arts, Library & information science, Mass communications, Music, Philosophy and Religion.

Download or read book Federation Proceedings written by Federation of American Societies for Experimental Biology and published by . This book was released on 1980-03 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1942- include proceedings of the American Physiological Society.

Download or read book Comprehensive Dissertation Index Chemistry P Z written by and published by . This book was released on 1984 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Textbook of Pediatric Infectious Diseases written by Ralph D. Feigin and published by W.B. Saunders Company. This book was released on 1992 with total page 1330 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Government Reports Announcements Index written by and published by . This book was released on 1980-08 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Feeding Weight Obesity Abstracts written by and published by . This book was released on 1978 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comprehensive Dissertation Index written by University Microfilms International and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 1984 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: