Download or read book Virtual Environment for Manipulating Microscopic Particles With Optical Tweezers written by and published by DIANE Publishing. This book was released on with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Photorefractive Optoelectronic Tweezers and Their Applications written by Michael Esseling and published by Springer. This book was released on 2014-07-31 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the never-ending quest for miniaturization, optically controlled particle trapping has opened up new possibilities for handling microscopic matter non-invasively. This thesis presents the application of photorefractive crystals as active substrate materials for optoelectronic tweezers. In these tweezers, flexible optical patterns are transformed into electrical forces by a photoconductive material, making it possible to handle matter with very high forces and high throughput. Potential substrate materials’ properties are investigated and ways to tune their figures-of-merit are demonstrated. A large part of the thesis is devoted to potential applications in the field of optofluidics, where photorefractive optoelectronic tweezers are used to trap, sort and guide droplets or particles in microfluidic channels, or to shape liquid polymers into optical elements prior to their solidification. Furthermore, a new surface discharge model is employed to discuss the experimental conditions needed for photorefractive optoelectronic tweezers.
Download or read book Optical Tweezers written by Miles J. Padgett and published by CRC Press. This book was released on 2010-06-02 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The technical development of optical tweezers, along with their application in the biological and physical sciences, has progressed significantly since the demonstration of an optical trap for micron-sized particles based on a single, tightly focused laser beam was first reported more than twenty years ago. Bringing together many landmark papers on
Download or read book Optical Trapping and Manipulation written by Philip Jones and published by MDPI. This book was released on 2020-11-25 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are pleased to present “Optical Trapping and Manipulation: From Fundamentals to Applications”, a Special Issue of Micromachines dedicated to the latest research in optical trapping. In recognition of the broad impact of optical manipulation techniques across disciplines, this Special Issue collected contributions related to all aspects of optical trapping and manipulation. Both theoretical and experimental studies were welcome, and applications of optical manipulation methods in fields including (but not limited to) single molecule biophysics, cell biology, nanotechnology, atmospheric chemistry, and fundamental optics were particularly welcome in order to showcase the breadth of the current research. The Special Issue accepted diverse forms of contributions, including research papers, short communications, methods, and review articles representing the state-of-the-art in optical trapping.
Download or read book Development of a Dual Joystick controlled Optical Trapping and Cutting System for Optical Micro manipulation of Cells written by Marcellinus Stevie Harsono and published by . This book was released on 2011 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many situations there is a need to physically manipulate microscopic objects with as much dexterity as our own hands provide in the macroscopic world. An example would be applying stresses onto cells in order to determine their mechanical properties. Our existing microscope-laser experimental system is capable of manipulating microscopic objects using two optical tweezers and one optical scissors to move and cut these objects, respectively. Despite these capabilities, however, the point-and-click user interface for optical trapping and cutting was cumbersome and hard to use, limiting the system's potential for micro-manipulation. In order to resolve this limitation, a new, more intuitive and hands-on user interface using two joysticks was designed and developed from the ground up in order to provide responsive, real-time control of the optical tweezers and scissors for microscopic manipulation. This new joystick user interface was then used to verify whether or not forces other than those due to microtubule dynamics act upon chromosomes during mitosis, tested in mitotic PtK2 and Indian Muntjac cells by 1) depolymerizing microtubules using nocodazole, and 2) disrupting microtubules using laser ablation with optical scissors, and subsequently attempting to freely manipulate chromosomes using joystick-controlled optical trapping.
Download or read book Cavity Optomechanics with Optically Trapped Particles written by Pau Mestres Junqué and published by . This book was released on 2018 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical trapping and manipulation have emerged as powerful tools to investigate single microscopic objects in a controlled environment. Using the momentum carried by light, forces can be exerted to confine and manipulate objects in a wide range of conditions ranging from liquid environments to high vacuum. In this thesis I implement different optical manipulation schemes to trap nano-objects and coupled them to optical cavities, giving rise to a cavity optomechanical interaction between the trapped object and the cavity mediated by the light¿s radiation-pressure. In a first experiment I implement a mobile optical tweezer (MobOT) with nanometer precision to place a levitated silica nanosphere at the standing wave of a high Finesse Fabry-Perot cavity aiming to cool its center of mass motion to the ground state at room temperature. To attain this goal I design a two step cooling process that starts with a parametrical modulation of the optical trapping potential which pre-cools the center of mass motion along the three axis. Then driving the cavity with a red-detuned laser furthers cool the particle motion along the cavity axis via the optomechanical interaction. To monitor the particle motion in the optical trap, I implement a highly robust and sensitive detection scheme that collects the trap forward scattered field and sends it to a set of three balanced photodiodes. According to a semiclassical model I present, this approach can resolve the nanoparticle motion down to a single phonon excitation provided a shot noise limited balance detector. I also study the use of plasmonic nanoapertures as a novel optomechanical system that increases by 10̂8 the single photon optomechanical coupling strength between the trapped nanoparticle and the cavity. These experiments are performed in the overdamped regime and result into a large optomechanical interaction that allows direct measurement of dynamical modulation of the trapping potential due to the motion of the trapped object. Different detuning regimes are studied aiming to improve the optical trapping performances at low laser intensities. These findings are supported by finite element simulations. Finally I have also made use of optical traps to perform non-equilibrium thermodynamic processes with an optically trapped microparticle in a virtual thermal bath. The virtual bath consists of an electrical white noise force. The agreement between the temperatures obtained from equilibrium and non-equilibrium measurements demonstrates the accuracy of this method. Supported by theory and simulations, our experiments highlight the importance of properly choosing the sampling rate and noise bandwidth for the validity of the method. We apply this technique to study non-equilibrium isothermal compression-expansion cycles at different temperatures ranging from room temperature to 3000K. We calculate some thermodynamic functionals for these processes such as work, heat and entropy. We show that work distributions verify the Crooks fluctuation theorem, and that they fit well to a generalized Gamma Function.
Download or read book Optical Trapping And Manipulation Of Neutral Particles Using Lasers A Reprint Volume With Commentaries written by Arthur Ashkin and published by World Scientific. This book was released on 2006-12-29 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume contains selected papers and extensive commentaries on laser trapping and manipulation of neutral particles using radiation pressure forces. Such techniques apply to a variety of small particles, such as atoms, molecules, macroscopic dielectric particles, living cells, and organelles within cells. These optical methods have had a revolutionary impact on the fields of atomic and molecular physics, biophysics, and many aspects of nanotechnology.In atomic physics, the trapping and cooling of atoms down to nanokelvins and even picokelvin temperatures are possible. These are the lowest temperatures in the universe. This made possible the first demonstration of Bose-Einstein condensation of atomic and molecular vapors. Some of the applications are high precision atomic clocks, gyroscopes, the measurement of gravity, cryptology, atomic computers, cavity quantum electrodynamics and coherent atom lasers.A major application in biophysics is the study of the mechanical properties of the many types of motor molecules, mechanoenzymes, and other macromolecules responsible for the motion of organelles within cells and the locomotion of entire cells. Unique in vitro and in vivo assays study the driving forces, stepping motion, kinetics, and efficiency of these motors as they move along the cell's cytoskeleton. Positional and temporal resolutions have been achieved, making possible the study of RNA and DNA polymerases, as they undergo their various copying, backtracking, and error correcting functions on a single base pair basis.Many applications in nanotechnology involve particle and cell sorting, particle rotation, microfabrication of simple machines, microfluidics, and other micrometer devices. The number of applications continues to grow at a rapid rate.The author is the discoverer of optical trapping and optical tweezers. With his colleagues, he first demonstrated optical levitation, the trapping of atoms, and tweezer trapping and manipulation of living cells and biological particles.This is the only review volume covering the many fields of optical trapping and manipulation. The intention is to provide a selective guide to the literature and to teach how optical traps really work.
Download or read book Proceedings written by and published by . This book was released on 2003 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanorobotics written by Vic Lynn & Kit Cooley and published by Scientific e-Resources. This book was released on 2018-01-21 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 1980s and 1990s, a handful of authors began speculating about the physical forms that future medical nanorobots might take. A few created artist's conceptions of their devices. During this time, only the broadest analyses of the missions and capabilities that might be desired had been attempted. Detailed technical and engineering studies, in many cases, still lay years in the future. Despite this handicap, some of these designs have many plausible elements, along with other elements which, in hindsight, may appear fanciful, impractical, or even dangerous. These speculations continue through the present. The science of nanorobotics plays a vital role in the development of robots, whose structure is built by using nanoscale components and objects. The nature of the components being in the nano scale allows the researchers for the engineering of the mimic of human beings. The construction of the various complex parts, which constitute the robots have been possible due to nanorobotics. Nanobots, nanites, nanoids or nanomites are some of the hypothetical devices created with the knowledge of nanorobotics. Nanorobotics will set new standards in pharmaceuticals, cosmetics, aerospace and automotive industries, security, defense, environmental protection, electronics, computers and communications. Within the next two decades, we may have tiny machines inside us, combatting every disease known to humankind and slowing down, even reversing the aging process, making us practically immortal. This book describes how to build a mobile computer user a citizen of the Internet and how to admittance everything the in sequence superhighway has to present. The objective of this book is to make available you with an opening to the design and completion of Internet protocols that are helpful for maintaining network connections still while moving from place to position.
Download or read book Applications of Microfluidic Chips in Optical Manipulation Photoporation written by Robert Frank Marchington and published by . This book was released on 2010 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigation of Cytoskeletal Systems with Optical Tweezers written by Kai Uhrig and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2009-10 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical tweezers are a versatile tool to apply and measure forces in the piconewton range on microscopic objects that are held by optical forces in a focused laser beam. We employed holographic optical tweezers (HOT) to create extended force sensor arrays, consisting of multiple trapped particles that were controlled and probed individually. The combination of high-speed video microscopy with fluorescence imaging allowed the visualization of labeled protein structures in parallel with the tracking of multiple trapped particles for force measurements. Using this setup, we could perform quantitative force measurements on biological samples with HOT for the first time. This provided the possibility to measure dynamic processes such as the contractility of two-dimensional cross-linked actin networks in the microfluidic flow cell. To investigate bundling processes between filaments, a method has been established using dynamic HOT to manipulate zipper-like structures between trapped particles actively. In a different set of experiments, the adhesion process of the Malaria parasite Plasmodium was investigated.Using optical tweezers, the formation of adhesion sites was probed.
Download or read book Interactive Virtual Reality Simulation for Nanoparticle Manipulation and Nanoassembly Using Optical Tweezers written by Krishna C. Bhavaraju and published by . This book was released on 2008 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Haptics Generating and Perceiving Tangible Sensations Part II written by Astrid M. L. Kappers and published by Springer Science & Business Media. This book was released on 2010-06-30 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the conference on Haptics: Generating and Perceiving Tangible Sensations, held in Amsterdam, Netherlands in July 2010.
Download or read book A Study of Dynamics in Microscopic Systems Using Optical Tweezers written by Thomas James Smart and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book World Congress of Medical Physics and Biomedical Engineering 2006 written by Sun I. Kim and published by Springer Science & Business Media. This book was released on 2007-07-05 with total page 4361 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings of the World Congress 2006, the fourteenth conference in this series, offer a strong scientific program covering a wide range of issues and challenges which are currently present in Medical physics and Biomedical Engineering. About 2,500 peer reviewed contributions are presented in a six volume book, comprising 25 tracks, joint conferences and symposia, and including invited contributions from well known researchers in this field.
Download or read book Optical Tweezers written by Philip H. Jones and published by Cambridge University Press. This book was released on 2015-12-03 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the theory, practice and applications of optical tweezers, combining state-of-the-art research with a strong pedagogic approach.
Download or read book Handbook of Nanophysics written by Klaus D. Sattler and published by CRC Press. This book was released on 2010-09-17 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nan
