Download or read book Use of Novel Techniques to Quantify Phenotypes in Biological Treatment Process written by K. G. Robinson and published by IWA Publishing. This book was released on 2004-01-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research attempts to evaluate nitrification treatment performance in combined carbon/nitrogen municipal wastewater reactors using traditional physical/chemical methods and modern molecular techniques. Bench scale activated sludge reactors were operated at different SRTs under varying DO levels and temperatures over a 21-month period. Real-time PCR assays were used to determine cell concentrations of total bacterial 16S rDNA, a gross measure of biomass content, the amoA gene, a measure of ammonia-oxidizing bacteria (AOB), and the Nitrospira 16S rDNA gene, a measure of nitrite-oxidizing bacteria (NOB). As expected, gravimetric biomass and total bacterial 16S rDNA levels increased with increasing SRT. Ammonia oxidation rates and N. oligotropha-type AOB concentrations did not follow similar trends with respect to changes in SRT, temperature, and DO nor were they highly correlated. The concentration of available nitrite and SRT were positively correlated with Nitrospira cell densities, while DO concentration and temperature were negatively correlated with NOB levels. The percentage of the total population comprised of AOB and NOB obtained with the real-time PCR assays were compared to predicted values estimated from design equations using typical kinetic parameters. While the percentages of NOB measured using the real-time PCR assay corresponded very well with the predicted values, the measured percentages of AOB were much lower than those estimated from the design equations, suggesting that N. oligotropha-type AOB were not the dominant ammonia-oxidizing species in these reactors. This publication can be purchased and downloaded via Pay Per View on Water Intelligence Online - click on the Pay Per View icon below

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Download or read book Microfluidics in Cell Biology Part C Microfluidics for Cellular and Subcellular Analysis written by and published by Academic Press. This book was released on 2018-11-22 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids, microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more. - Contains contributions from experts in the field from across the world - Covers a wide array of topics on both mitosis and meiosis - Includes relevant, analysis based topics

Download or read book Machine Learning Techniques on Gene Function Prediction written by Quan Zou and published by Frontiers Media SA. This book was released on 2019-12-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Plant Metabolomics written by Kazuki Saito and published by Springer Science & Business Media. This book was released on 2006-06-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

Download or read book The American Psychiatric Association Publishing Textbook of Substance Use Disorder Treatment written by Kathleen T. Brady and published by American Psychiatric Pub. This book was released on 2021-01-15 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: A robust revision, including many entirely new chapters addressing policy, the latest treatment approaches, and special topics, the Sixth Edition of The American Psychiatric Association Publishing Textbook of Substance Use Disorder Treatment offers a comprehensive and compelling review of this ever-evolving field. New sections address important topics that have gained prominence or become the focus of increased research attention since the Fifth Edition was released. For example, substance use and other psychiatric disorders often co-occur, and the resulting dual disorder is frequently associated with greater symptom severity and worse long-term prognosis than either disorder alone. Accordingly, the section on psychiatric comorbidity covers the epidemiology, assessment, and treatment of substance use disorders (SUDs) that co-occur with psychotic, mood, anxiety, eating, attention-deficit/hyperactivity, or trauma-related disorders. The section devoted to special populations has been revamped, and the topics have been thoroughly updated, some now covered by new contributors and others completely new to this edition. SUDs among women (including perinatal issues), adolescents, patients with chronic pain, sexual and gender minority populations, and older adults are addressed in detailed chapters, as are behavioral addictive disorders and cross-cultural aspects of substance-related and addictive disorders. Finally, the editors have included a section devoted to critically important topics in public health, including the U.S. opioid epidemic, cannabis policy and use, HIV/AIDS and hepatitis C, nicotine and public health, and the prevention of SUDs. New or noteworthy coverage includes the following: A chapter devoted to the legal and practical aspects of addiction in the occupational sphere, designed for clinicians who treat people with SUDs and/or develop workplace testing programs, employee assistance programs, and occupational drug/alcohol policies for these workers. A chapter that surveys the growing literature supporting the use of mindfulness, exercise, and other "mind and body" practices (e.g., yoga, acupuncture, tai chi) as complements or alternatives to standard SUD treatment models. A chapter devoted to hallucinogens, which clarifies their actions, psychoactive effects, historical uses, potential therapeutic benefits, and neural mechanisms, and both identifies their risks and seeks to dispel some of the misconceptions that have continued to surround them. A suite of chapters devoted to cannabis, encompassing a review of its neurobiology and history, a survey of effective treatment approaches and harm-reduction strategies for cannabis use disorder, and a consideration of evolving public policy around cannabis use. A trio of chapters devoted to nicotine and tobacco, encompassing a review of neurobiology, a survey of clinical assessment tools, a summary of the research base for effective treatments for tobacco use disorder, and a consideration of public health policy and interventions regarding tobacco use. Evidence-based, down to earth, and meticulously edited, the new Sixth Edition of The American Psychiatric Association Publishing Textbook of Substance Use Disorder Treatment is an essential resource for clinicians who treat SUDs in a variety of settings -- from examining rooms to emergency departments, and from hospitals to recovery facilities.

Download or read book Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer Volume II written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-11-29 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Download or read book Henry s Clinical Diagnosis and Management by Laboratory Methods E Book written by Richard A. McPherson and published by Elsevier Health Sciences. This book was released on 2011-09-06 with total page 1769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Download or read book Data Science in Critical Care An Issue of Critical Care Clinics E Book written by Rishikesan Kamaleswaran and published by Elsevier Health Sciences. This book was released on 2023-09-13 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Critical Care Clinics, guest editors Drs. Rishikesan Kamaleswaran and Andre L. Holder bring their considerable expertise to the topic of Data Science in Critical Care. Data science, the field of study dedicated to the principled extraction of knowledge from complex data, is particularly relevant in the critical care setting. In this issue, top experts in the field cover key topics such as refining our understanding and classification of critical illness using biomarker-based phenotyping; predictive modeling using AI/ML on EHR data; classification and prediction using waveform-based data; creating trustworthy and fair AI systems; and more. - Contains 15 relevant, practice-oriented topics including AI and the imaging revolution; designing "living, breathing clinical trials: lessons learned from the COVID-19 pandemic; the patient or the population: knowing the limitations of our data to make smart clinical decisions; weighing the cost vs. benefit of AI in healthcare; and more. - Provides in-depth clinical reviews on data science in critical care, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Assess written by Lakhdar Lamari and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer program which performs image analysis for measuring the extent of plant diseases.

Download or read book Sharing Publication Related Data and Materials written by National Research Council and published by National Academies Press. This book was released on 2003-04-17 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologists communicate to the research community and document their scientific accomplishments by publishing in scholarly journals. This report explores the responsibilities of authors to share data, software, and materials related to their publications. In addition to describing the principles that support community standards for sharing different kinds of data and materials, the report makes recommendations for ways to facilitate sharing in the future.

Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Download or read book The Secret Chain written by Michael Bradie and published by State University of New York Press. This book was released on 1994-12-15 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comparative Anatomy and Histology written by Piper M. Treuting and published by Academic Press. This book was released on 2012 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction -- 2. Phenotyping -- 3. Necropsy and histology -- 4. Mammary Gland -- 5. Skeletal System -- 6. Nose, sinus, pharynx and larynx -- 7. Oral cavity and teeth -- 8. Salivary glands -- 9. Respiratory -- 10. Cardiovascular -- 11. Upper GI -- 12. Lower GI -- 13. Liver and gallbladder -- 14. Pancreas -- 15. Endocrine System -- 16. Urinary System -- 17. Female Reproductive System -- 18. Male Reproductive System -- 19. Hematopoietic and Lymphoid Tissues -- 20. Nervous System -- 21. Special senses, eye -- 22. Special senses, ear -- 23. Skin and adnexa -- Index.