Download or read book Transfusion Practices in High risk Patients in the Intensive Care Unit written by Senta Jorinde Raasveld and published by . This book was released on 2024 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Transfusion has been a topic of interest for centuries. Nowadays, it is one of the key treatments in patients admitted to the intensive care unit (ICU). Researchers have tried to find the optimal indications for transfusion in different settings (e.g., trauma vs. non-trauma), subpopulations (e.g., sepsis, post-cardiothoracic surgery) as well as the specifics of transfusion itself (e.g., blood vs. components, storage times). In the past decades, there has been increasing attention to the potential downsides of transfusion. These include patient -level factors, such as short- and long-term side-effects, as well as system-level factors such as donor shortages and increasing healthcare costs. This has led to different international non-inferiority randomized trials investigating whether it is safe to apply a restrictive transfusion policy. Overall, this has resulted in guidelines moving towards a more restrictive transfusion policy in ICU patients. While these data are important for the patient population as a whole, the individual patient may benefit from a personalized approach. The work in this thesis forms an epidemiological overview of transfusion practices in two domains: on one hand, the global mixed population in the ICU; on the other hand, patients supported with extracorporeal membrane oxygenation (ECMO). The different presented studies each highlighted a different aspect of transfusion. By focusing on actual transfusion behavior, we aimed to improve our understanding of how clinical studies and guideline recommendations are translated into clinical practice. Ultimately, the goal of this work was to provide a foundation for future research, implementation and education."--
Download or read book Transfusion in the Intensive Care Unit written by Nicole P. Juffermans and published by Springer. This book was released on 2014-09-30 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a high incidence of anemia, critically ill patients are frequently transfused, with up to 40% of patients receiving a transfusion during their stay in the Intensive Care Unit. It has become increasingly clear that there is an association between transfusion and adverse outcomes, underlining the need for a careful assessment of the risks and benefits of a blood transfusion. In the last decade, there have been several large clinical trials that have studied red blood cell transfusion triggers in various ICU patient populations, allowing us to take a personalized approach to transfusion. Moreover, ICU patients often suffer from coagulopathy. Recent studies have addressed the effectiveness of fresh frozen plasma and platelets to prevent or treat bleeding. Aiming at a personalized therapy approach in transfusion practice, this book is the first to offer a comprehensive summary of transfusion triggers for red blood cells in specific ICU patient populations and specific conditions. In addition, it discusses evidence for triggers for plasma and platelets and outlines the most common adverse effects of transfusion in the ICU. Transfusion in the Intensive Care Unit is a practical handbook that can be used in everyday practice to guide transfusion and thus will serve as a valuable resource for physicians, fellows and residents working in Intensive Care, Anesthesiology and Cardiac Surgery.
Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Neonatal Transfusion Practices written by Deborah A. Sesok-Pizzini and published by Springer. This book was released on 2016-11-12 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise yet comprehensive review of neonatal transfusion medicine. The text covers major areas of the field, including chapters dedicated to pre transfusion testing, manufacturing, standards and storage; blood product administration; special congenital and acquired disorders in the neonate; hemolytic disease of the newborn; intrauterine transfusions; adverse reactions; and ECMO. The volume features contributions from a diverse group of experts in the field and include pathologists, anesthesiologists, neonatologists, a pediatric hematologist and oncologist, and a high-risk obstetrician. These authors contribute their unique expertise and perspectives to the practice of neonatal transfusion medicine and allow the reader to experience an in depth introduction to each of the chapter topics. Neonatal Transfusion Practices is a valuable, go-to reference that addresses some of the more frequent questions asked by clinicians and professionals who have limited exposure to neonatal transfusion practices. /div
Download or read book Patient Blood Management written by Hans Gombotz and published by Thieme. This book was released on 2015-11-10 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient Blood Management (PBM) is an innovative clinical concept that aims to reduce the need for allogenic blood transfusions, cut health-care costs, and avert or correct the risk factors related to blood transfusion, thus minimizing the rate of side effects and complications. This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia tolerance. The book also goes beyond preoperative PBM, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. Special Features: Presents a clear three-pillar strategy for the application of PBM: diagnosis and treatment of anemia, reduction of peri-interventional blood loss, and optimization of the tolerance to anemia in the everyday clinical setting Covers issues such as PBM during surgery, requirements for modern transfusion medicine, ordering blood products, the role of pre-anesthesia clinics, benchmarking processes, and potential implications of PBM in the public health sector Overview of research in PBM including landmark studies and current clinical trials Boxes in each chapter highlighting key information, core statements, and summaries A multidisciplinary and international team of contributors experienced in PBM Patient Blood Management is a guide for clinicians and residents whose patients are at risk for anemia, coagulation disorders, or severe blood loss. Anesthesiologists, surgeons, and specialists involved in the use of blood and blood products can use the book for quick reference or to learn more about a leading-edge concept for optimizing patient safety and improving outcome.
Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).
Download or read book ECMO Extracorporeal Cardiopulmonary Support in Critical Care 5th Edition written by Elso and published by . This book was released on 2017-02-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book AWHONN s High Risk Critical Care Obstetrics written by Nan H. Troiano and published by Lippincott Williams & Wilkins. This book was released on 2018-02-16 with total page 827 pages. Available in PDF, EPUB and Kindle. Book excerpt: Develop top-level guidelines for high-risk and critically ill pregnancy women with AWHONN High-Risk & Critical Care Obstetrics, 4th Edition, an official publication of the Association of Women’s Health, Obstetric & Neonatal Nurses (AWHONN). This comprehensive analysis of critical care obstetrics concepts offers summary of research findings and top-notch clinical expertise. This is the expert guidance you need to navigate complex patient conditions and promote safe, effective perinatal care.
Download or read book Anesthesia for the High Risk Patient written by Ian McConachie and published by Cambridge University Press. This book was released on 2009-04-09 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews pre-, intra- and post-operative management of many of the most complicated and sick patients requiring anaesthesia for surgery.
Download or read book Clinical Trials for the Treatment of Sepsis written by W.J. Sibbald and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establishing source control, and then modifies the host's response to the excessive inflammatory response which characterizes sepsis. This book is a comprehensive review by internationally recognized experts of the epidemiology, monitoring and treatment of sepsis. Using an "evidence-based" approach, it comprises an extensive review of the literature on sepsis, provides up-to-date recommendations for monitoring and treating sepsis patients, and concludes with explicit recommendations for the design and monitoring of future clinical trials.
Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.
Download or read book Risk Management in Blood Transfusion Medicine written by J. Mills Barbeau and published by Elsevier Health Sciences. This book was released on 2019-01-03 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of risk management in transfusion medicine from Dr. James Mills Barbeau. This practical resource presents a summary of today’s state-of-the-art techniques for reducing harm during all phases of transfusion practice, including blood collection, testing, processing, clinical assessment, and transfusion. It’s an easy-to-read, one-stop resource for managing and mitigating the various levels of risk in a variety of transfusion settings and scenarios. Presents a well-rounded perspective on quality assurance, blood supply testing, clinical risk, ethical and legal considerations, and transfusion-transmitted infectious diseases. Demonstrates how transfusion risk-management programs add value to health care institutions by enhancing a culture of safety, improving the institution’s reputation, and improving the bottom line. Consolidates today’s available information on risk management in blood transfusion medicine into one convenient resource.
Download or read book Blood Donor Selection written by World Health Organization and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO guidelines on assessing donor suitability for blood donation have been developed to assist blood transfusion services in countries that are establishing or strengthening national systems for the selection of blood donors. They are designed for use by policy makers in national blood programmes in ministries of health, national advisory bodies such as national blood commissions or councils, and blood transfusion services.
Download or read book Damage Control Resuscitation written by Philip C. Spinella and published by Springer. This book was released on 2019-08-12 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of damage control resuscitation (DCR), an evidence-based approach to the resuscitation of patients with severe life-threatening hemorrhage (LTH). It focuses on both civilian and military applications as DCR is utilized in civilian trauma situations as well as combat casualty care settings. The book covers the history of fluid resuscitation for bleeding, epidemiology of severe traumatic injuries, prediction of life-threatening hemorrhage, pathophysiology and diagnosis of blood failure, and permissive hypotension. Chapters provide in-depth detail on hemostatic resuscitation principles, dried plasma, dried platelet surrogates, and recent developments in frozen red blood cells and oxygen carriers. The book also discusses how DCR principles can be used in a variety of situations such as when there are large numbers of patients with hemorrhagic lesions, non-trauma scenarios, and on distinct populations such as children. Finally, it concludes with a discussion of training and education methods for the implementation of DCR and remote DCR principles as well as learning healthcare system principles to facilitate the implementation of DCR and ultimately improve outcomes for patients with life-threatening hemorrhage. Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage is an essential resource for physicians and related professionals, residents, nurses and medical students in emergency medicine, anesthesia, surgery, and critical care, as well as civilian and military EMS providers.
Download or read book General Principles of Blood Transfusion written by American Medical Association and published by . This book was released on 1985 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Intensive Care Unit Manual written by Paul N. Lanken and published by Elsevier Health Sciences. This book was released on 2013-09-26 with total page 1410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intensive Care Unit Manual is a practical, hands-on, how-to manual that covers the full spectrum of conditions encountered in the ICU, guiding you step-by-step from your initial approach to the patient through diagnosis and treatment. Compact, affordable, and comprehensive, the ICU Manual puts all the critical care information you need right at your fingertips! Stay at the forefront of critical care with a practice-oriented, relevant, and well-illustrated account of the pathophysiology of critical disease, presented in a highly readable format. Gain valuable insight into the recognition, evaluation, and management of critical conditions such as respiratory, hemodynamic, and infectious diseases; management of ICU patients with special clinical conditions; cardiovascular, hematologic, and neurological disorders; poisoning and overdoses; trauma and burns; and much more! Grasp the latest developments in critical care with extensive updates and revisions to several key chapters, as well as brand-new chapters on Alcohol Withdrawal Syndromes; Acute Heart Failure Syndromes; Noninvasive Ventilation; and more ICU conditions. Understand and apply the most important ICU practices, including management of acute respiratory failure, mechanical ventilation, invasive hemodynamic monitoring, and the care of patients with special needs, AIDS, end-stage renal disease, or end-stage liver disease. Get convenient access to the full text and image library online at Expert Consult, in addition to online-only text, figures, and tables from the Alcohol Withdrawal Syndromes and Acute Heart Failure Syndromes chapters.
