Download or read book Toxicity of Xanthoparmelia Chlorochroa and the Lichen Substance usnic Acid in Ruminants written by Rebecca N. Dailey and published by ProQuest. This book was released on 2008 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although Xanthoparmelia chlorochroa was identified as the putative etiology in the death of an estimated 400-500 elk (Cervus canadensis) on the Red Rim-Daley Wildlife Habitat Management Area (WHMA) in Wyoming during the winter of 2004, there is little information regarding X. chlorochroa and the biological activity of its secondary metabolites. Based on in vivo studies, laboratory experiments and field observations, it was determined that (1) toxicity of X. chlorochroa varies by location and/or time of year, (2) (+)-usnic acid is not the toxic component of X. chlorochroa directly responsible for the syndrome observed in lichen poisoned animals, (3) ultra-performance liquid chromatography tandem-mass spectroscopy (UPLC-MS-MS) results show differences in the concentration of salazinic and usnic acids among lichen samples collected from locales associated with lichen poisonings, (4) mice may be useful as a research tool for identifying possible toxin(s), because they respond similarly to lichen-affected ruminants, and (5) field cases are not uncommon and urine from affected animals may be a promising diagnostic sample.
Download or read book Poisoning By Plants Mycotoxins and Related Toxins written by Franklin Riet-Correa and published by CABI. This book was released on 2011 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive collection of up-to-the-minute research in the field of poisonous plants investigates the effects of toxins on animals and humans. It covers the effects of poisonous plants on the liver, the reproductive system, and the nervous system, as well as exploring the field of herbal medicine. In a specialized section devoted to control measures, the book highlights techniques such as vaccination and taste aversion, providing the reader with important information on safeguarding against disaster. This volume is an essential reference for veterinarians, researchers, toxicologists and.
Download or read book Proceedings of Annual Meeting written by American Association of Veterinary Laboratory Diagnosticians. Meeting and published by . This book was released on 2006 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lichen Secondary Metabolites written by Branislav Ranković and published by Springer. This book was released on 2019-07-26 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and extended edition provides in-depth insights into the benefits and untapped potential of lichen-derived bioactive compounds. The whole spectrum of these compounds’ biological and medical functions, from antibiotic to antiviral and anti-carcinogenic properties, is presented. In addition, a new chapter discusses the anti-neurodegenerative and anti-diabetic activities of lichenic secondary metabolites. Given its scope, the book offers a valuable asset for students and researchers in this field.
Download or read book Reflections written by University of Wyoming. College of Agriculture and published by . This book was released on 2006 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies in Natural Products Chemistry written by Elfie Stocker-Wörgötter and published by Elsevier Inc. Chapters. This book was released on 2013-03-15 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lichens are fascinating symbiotic organisms, biosynthesizing a broad spectrum of interesting secondary metabolites and polysaccharides. A considerable number of them have been found to exert biological activities, such as antibiotic, antimycobacterial, antiviral, anti-inflammatory, analgesic, antipyretic, antiproliferative, and cytotoxic effects. Only a very low percentage of “lichen substances” have been actually screened for their biological activities and their potential therapeutic applications in medicine. This is due to difficulties to obtain large quantities of lichens from nature, isolated lichen fungi and algae from cultures for extractions. Ten years ago, we have started to bypass these problems by introducing first traditional and then by exploring novel microbiological techniques and advanced molecular tools for our culture experiments. “Case studies” with selected cultured mycobionts and photobionts, accumulating considerable quantities of a focused compound, have been performed as tests for large-scale culturing, to be able to utilize facilities like phytotrons and bioreactors (small-scale bioreactors) for future approaches. Further studies have focused on the chemical identification of the metabolites from cultures and the genetic characterization of lichen PKS genes (Polyketide synthase genes). Another interesting group of lichen metabolites is cell wall polysaccharides. All lichen species investigated so far produce these polymers in considerable amounts and many of them have been shown to exhibit antitumor, immunostimulating, antiviral as well as other types of biological activity. Lichens polysaccharides are mainly of the following structural types: α-glucans (isolichenan, nigeran, pseudonigeran, and pullulan), β-glucans (lichenan, pustulan, laminaran, and lentinan-type glucan), galactomannans, and complex heteroglycans (galactoglucomannan, galactomannoglucan, rhamnopyranosylgalactofuranan, and glucomannan). Investigations on lichen polysaccharides were carried out using material extracted from the entire thallus with no mention of the origin of component polymers (fungal partner or photobiont). In order to understand the contribution of the symbiotic partners to the polysaccharide present in the lichen thallus, the carbohydrates produced by some aposymbiotically cultured mycobionts and photobionts (Trebouxia, Asterochloris, and Coccomyxa) were analyzed. The studies demonstrated that most of the polysaccharides previously found in the symbiotic thalli were also produced by the aposymbiotically cultivated fungal partner, while there were no similarities between the polysaccharides extracted from the photobiont with those from the respective lichen. Surprisingly, the photobionts synthesized very interesting polysaccharides, such as β-galactofuranan, mannogalactofuranan, rhamnopyranosylgalactofuranan, and an O-methylated mannogalactan. One of them was biologically active, having in vitro activity on murine peritoneal macrophages.
Download or read book Antifungal Compounds Discovery written by Marina Sokovic and published by Elsevier. This book was released on 2020-09-18 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compounds Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections. Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field. Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compounds Discovery is a comprehensive guide helping researchers understand the relationship between specific chemical structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds. Provides an overview of the most specific mycotic infections and fungal species as background for compound development Presents the chemical formulas of all natural and synthetic compounds reviewed Combines detailed information about origin, isolation and possible therapeutic uses of all indexed compounds, including biological activity, mechanism of action and SAR information
Download or read book Recent Advances in Lichenology written by Dalip Kumar Upreti and published by Springer. This book was released on 2016-10-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail molecular, mycobiont culture, biomonitoring and bioprospection of lichens, providing insights into advances in different fields of lichenology by applying modern techniques and approaches and examining how their application has enhanced or changed classical approaches. It offers a valuable resource, especially for beginners, students and researchers from different academic backgrounds interested in the study of lichens. In recent years, the introduction of modern analytical techniques and approaches has significantly improved our understanding of the environment, including lichens. Lichens are unique organisms which possess untapped potential as effective and reliable bioindicators, sources of therapeutic phytochemicals, and as excellent extremophiles. The unique and peculiar characteristics of lichens underline the need for a multidimensional approach to explore their potential in various fields of environment science, botany and chemistry. Modern techniques, especially molecular techniques, have greatly enriched the field of lichen taxonomy and its position in the plant kingdom, revealing little-known species and exploring their evolutionary history, while multivariate analysis and GIS approaches have established lichens as an ideal and reliable tool for monitoring air pollution. Advanced culture techniques have expanded the pharmacological applications of lichens, which was formerly restricted due to their small biomass. The advent of sophisticated analytical instrumentation has now facilitated the isolation and characterization of lichens’ bioactive constituents, even in lower concentrations, as well as the estimation of their stress responses at different levels of pollution. As lichen diversity is adversely affected by increasing air pollution, there is a pressing need to develop effective management practices to conserve, restore and document lichen diversity.
Download or read book Chemistry Biochemistry and Biology of 1 3 Beta Glucans and Related Polysaccharides written by Antony Bacic and published by Academic Press. This book was released on 2009-07-07 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides presents a comprehensive, systematic and authoritative survey of information about a family of chemically related, but functionally diverse, naturally occurring polysaccharides--the (1-3)-glucans. International contributors describe the chemical and physicochemical properties of these glucans and their derivatives and the molecular biological and structural aspects of the enzymes involved in their formation and breakdown. A detailed analysis of their physiological roles in the various biological situations in which they are found will be provided. Additionally, evolutionary relationships among the family of these glucans will be described. Topics of medical relevance include detailing the glucans' interactions with the immune system and research for cancer therapy applications Web resource links allow scientists to explore additional beta glucan research Separate indexes divided into Species and Subject for enhanced searchability
Download or read book High Altitude Primates written by Nanda B. Grow and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic goal of the volume is to compile the most up to date research on how high altitude affects the behavior, ecology, evolution and conservation status of primates, especially in comparison to lowland populations. Historically, the majority of primate studies have focused on lowland populations. However, as the lowlands have been disappearing, more and more primatologists have begun studying populations located in higher altitudes. High altitude populations are important not only because of their uniqueness, but also because they highlight the range of primate adaptability and the complex variables that are involved in primate evolution. These populations are good examples of how geographic scales result in diversification and/or speciation. Yet, there have been very few papers addressing how this high altitude environment affects the behavior, ecology, and conservation status of these primates.
Download or read book Biodeterioration of Stone Surfaces written by Larry St.Clair and published by Springer Science & Business Media. This book was released on 2012-11-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a timely volume in view of the considerable interest currently shown in the preservation of our cultural heritage, and the extensive and growing literature on the subject. Unfortunately, the latter is to be found in a wide variety of published sources, some aimed at a very specific readership and therefore not all that accessible to those who need this resource. The present volume draws together a spectrum of biodeterioration work from across the world to provide an overview of the materials examined and the methodologies employed to elucidate the nature of the problems, as well as an extensive and current bibliographical resource on lichen biodeterioration. Biodeterioration of historical and culturally important stone substrata is a complex problem to be addressed. Easy, risk-free solutions are simply not available to be dealt with by other than a wide range of expertise. Successful resolution of this issue will inevitably require a multidisciplinary effort, where biologists work in close cooperation with ecologists, geologists, geochemists, crystallographers, cultural property conservators, archaeologists, anthropologists, and historians in order to recommend the most effective management scheme. The advantage of this approach is obvious: multidisciplinary management teams with good leadership can ask more appropriate questions while developing much more thoughtful and informed decisions.
Download or read book Advances in Polyurethane Biomaterials written by Stuart L. Cooper and published by Woodhead Publishing. This book was released on 2016-01-23 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Polyurethane Biomaterials brings together a thorough review of advances in the properties and applications of polyurethanes for biomedical applications. The first set of chapters in the book provides an important overview of the fundamentals of this material with chapters on properties and processing methods for polyurethane. Further sections cover significant uses such as their tissue engineering and vascular and drug delivery applications Written by an international team of leading authors, the book is a comprehensive and essential reference on this important biomaterial. Brings together in-depth coverage of an important material, essential for many advanced biomedical applications Connects the fundamentals of polyurethanes with state-of-the-art analysis of significant new applications, including tissue engineering and drug delivery Written by a team of highly knowledgeable authors with a range of professional and academic experience, overseen by an editor who is a leading expert in the field
Download or read book Natural Product Chemistry for Drug Discovery written by Antony D. Buss and published by Royal Society of Chemistry. This book was released on 2010 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.
Download or read book Handbook of Textile and Industrial Dyeing written by M Clark and published by Elsevier. This book was released on 2011-10-25 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyeing is one of the most effective and popular methods used for colouring textiles and other materials. Dyes are employed in a variety of industries, from cosmetic production to the medical sector. The two volumes of the Handbook of textile and industrial dyeing provide a detailed review of the latest techniques and equipment used in the dyeing industry, as well as examining dyes and their application in a number of different industrial sectors.Volume 1 deals with the principles of dyeing and techniques used in the dyeing process, and looks at the different types of dyes currently available. Part one begins with a general introduction to dyeing, which is followed by chapters that examine various aspects of the dyeing process, from the pre-treatment of textiles to the machinery employed. Chapters in part two then review the main types of dyes used today, including disperse dyes, acid dyes, fluorescent dyes, and many others for a diverse range of applications.With its distinguished editor and contributions from some of the world’s leading authorities, the Handbook of textile and industrial dyeing is an essential reference for designers, colour technologists and product developers working in a variety of sectors, and will also be suitable for academic use. Examines dyeing and its application in a number of different industrial sectors Deals with the principles of dyeing and techniques used in the dyeing process, as well as types of dyes currently available Chapters review various dye types right through to modelling and predicting dye properties and the chemistry of dyeing
Download or read book Microbial Cell Factories Engineering for Production of Biomolecules written by Vijai Singh and published by Academic Press. This book was released on 2021-02-13 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs
Download or read book Biotechnology and Biology of Trichoderma written by Vijai G. Gupta and published by Newnes. This book was released on 2014-02-17 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology and Biology of Trichoderma serves as a comprehensive reference on the chemistry and biochemistry of one of the most important microbial agents, Trichoderma, and its use in an increased number of industrial bioprocesses for the synthesis of many biochemicals such as pharmaceuticals and biofuels. This book provides individuals working in the field of Trichoderma, especially biochemical engineers, biochemists and biotechnologists, important information on how these valuable fungi can contribute to the production of a wide range of products of commercial and ecological interest. Provides a detailed and comprehensive coverage of the chemistry, biochemistry and biotechnology of Trichoderma, fungi present in soil and plants Includes most important current and potential applications of Trichoderma in bioengineering, bioprocess technology including bioenergy & biofuels, biopharmaceuticals, secondary metabolites and protein engineering Includes the most recent research advancements made on Trichoderma applications in plant biotechnology and ecology and environment
