Download or read book Total Interaction written by Gerhard Buurmann and published by Walter de Gruyter. This book was released on 2005-04-22 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interactivity is the catchword for a wide range of innovative solutions that concept designers and engineers are developing in every area of technology and culture. For the authors interaction is more than a technological or aesthetic concept, it is a new means to ally humans and technology in a dynamic and reciprocal form of “living in technology”. This publication gathers together scientists and contributors from diverse fields of activity, providing a fascinating, up-to-date survey of the technological and conceptual equipment of experts engaged in aesthetic disciplines and product design. The editor, Professor Gerhard M. Buurman, is Head of Interactiondesign at the University of Art, Media and Design (HGKZ) in Zurich.
Download or read book Total Synthesis of Thielocin B1 as a Protein Protein Interaction Inhibitor of PAC3 Homodimer written by Kosuke Ohsawa and published by Springer. This book was released on 2015-01-13 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein–protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be novel therapeutic targets, while it is difficult to apply conventional methodology based on lock and key theory. The author achieved the first total synthesis of TB1 and its spin-labeled derivative to carry out NMR experiments because the supply of TB1 from natural sources was limited. Unique 2,2’,6,6’-tetrasubstituted diphenyl ether moiety of TB1 was synthesized from a depsidone skeleton by chemoselective reduction of lactone. In the process of elongating side wings, efficient formylation utilizing dichloromethyl methyl ether–silver trifluoromethanesulfonate was developed for the sterically hindered aromatic compound. NMR titration experiments and paramagnetic relaxation enhancement observation of PAC3 homodimer were performed with synthesized TB1 and its molecular probe, respectively. The results of the above NMR studies and additional in silico docking studies suggested that TB1 promotes the dissociation to monomeric PAC3 after interaction with PAC3 homodimer. The rare mechanism shown in this book indicates a potential novel drug target in the interfaces of PPIs with no cavity or groove.
Download or read book Protein Protein Interactions written by Weibo Cai and published by BoD – Books on Demand. This book was released on 2012-03-30 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.
Download or read book Investigations of Indiana Lakes and Streams written by and published by . This book was released on 1928 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Peer Interaction and Second Language Learning written by Masatoshi Sato and published by John Benjamins Publishing Company. This book was released on 2016-03-10 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the first collection of empirical studies focusing on peer interaction for L2 learning. These studies aim to unveil the impact of mediating variables such as task type, mode of interaction, and social relationships on learners’ interactional behaviors and language development in this unique and pedagogically powerful learning context. To examine these issues, contributors employed quantitative, qualitative, and mixed-methods designs as well as cognitive, social, and sociocognitive theoretical frameworks. The majority of the studies are classroom based and were conducted in a rich array of settings covering five continents and encompassing a wide range of learner L1s and target languages. These settings include second and foreign language classrooms from primary to university level, content-based programs, online contexts, and after-school programs. To span the divide between research and practice, each study includes a section suggesting pedagogical implications.
Download or read book Nuclear Structure Physics written by Amritanshu Shukla and published by CRC Press. This book was released on 2020-10-22 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear structure Physics connects to some of our fundamental questions about the creation of universe and its basic constituents. At the same time, precise knowledge on the subject has lead to develop many important tools of human kind such as proton therapy, radioactive dating etc. This book contains chapters on some of the crucial and trending research topics in nuclear structure, including the nuclei lying on the extremes of spin, isospin and mass. A better theoretical understanding of these topics is important beyond the confines of the nuclear structure community. Additionally, the book will showcase the applicability and success of the different nuclear effective interaction parameters near the drip line, where hints for level reordering have already been seen, and where one can test the isospin-dependence of the interaction. The book offers comprehensive coverage of the most essential topics, including: • Nuclear Structure of Nuclei at or Near Drip-Lines • Synthesis challenges and properties of Superheavy nuclei • Nuclear Structure and Nuclear models - Ab-initio calculations, cluster models, Shell-model/DSM, RMF, Skyrme • Shell Closure, Magicity and other novel features of nuclei at extremes • Structure of Toroidal, Bubble Nuclei, halo and other exotic nuclei These topics are not only very interesting from theoretical nuclear physics perspective but are also quite complimentary for ongoing nuclear physics experimental program worldwide. It is hoped that the book chapters written by experienced and well known researchers/experts will be helpful for the master students, graduate students and researchers and serve as a standard & uptodate research reference book on the topics covered.
Download or read book Applying Maths in the Chemical and Biomolecular Sciences written by Godfrey Beddard and published by Oxford University Press, USA. This book was released on 2009-09-03 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Godfrey Beddard is Professor of Chemical Physics in the School of Chemistry, University of Leeds, where his research interests encompass femtosecond spectroscopy, electron and energy transfer, and protein folding and unfolding. 1. Numbers, Basic Functions, and Algorithms 2. Complex Numbers 3. Differentiation 4. Integration 5. Vectors 6. Matrices and Determinants 7. Matrices in Quantum Mechanics 8. Summations, Series, and Expansion of Functions 9. Fourier Series and Transforms 10. Differential Equations 11. Numerical Methods 12. Monte-carlo Methods 13. Statistics and Data Analysis
Download or read book Principles of Radiation Interaction in Matter and Detection written by Claude Leroy and published by World Scientific. This book was released on 2011-09-23 with total page 1041 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, like the first and second editions, addresses the fundamental principles of interaction between radiation and matter and the principles of particle detection and detectors in a wide scope of fields, from low to high energy, including space physics and medical environment. It provides abundant information about the processes of electromagnetic and hadronic energy deposition in matter, detecting systems, performance of detectors and their optimization.The third edition includes additional material covering, for instance: mechanisms of energy loss like the inverse Compton scattering, corrections due to the Landau?Pomeranchuk?Migdal effect, an extended relativistic treatment of nucleus?nucleus screened Coulomb scattering, and transport of charged particles inside the heliosphere. Furthermore, the displacement damage (NIEL) in semiconductors has been revisited to account for recent experimental data and more comprehensive comparisons with results previously obtained.This book will be of great use to graduate students and final-year undergraduates as a reference and supplement for courses in particle, astroparticle, space physics and instrumentation. A part of the book is directed toward courses in medical physics. The book can also be used by researchers in experimental particle physics at low, medium, and high energy who are dealing with instrumentation.
Download or read book Research Methods in Social Relations written by Geoffrey Maruyama and published by John Wiley & Sons. This book was released on 2014-08-18 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methods in Social Relations, 8th Edition, features a series of updates and revisions in its comprehensive introduction to current research methods in the social and behavioural sciences. Offers comprehensive coverage of a wide variety of traditional and topical research methods Addresses many newer research approaches such as propensity score matching, mixed methods designs, and confirmatory factor analysis Written to be accessible to a range of social and behavioural science disciplines, including public health, political science, sociology, and psychology Includes new chapters that engage readers in critical thinking about the processes involved in building sustainable partnerships in field and community settings The Companion website includes an array of resources for Instructors, including Test Banks, Power Point lecture slides, discussion questions and exercises This new edition is the much-anticipated follow-up to 2001’s seventh edition by Hoyle, Harris and Judd
Download or read book Human Computer Interaction INTERACT 2013 written by Paula Kotzé and published by Springer. This book was released on 2013-07-30 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: The four-volume set LNCS 8117-8120 constitutes the refereed proceedings of the 14th IFIP TC13 International Conference on Human-Computer Interaction, INTERACT 2013, held in Cape Town, South Africa, in September 2013. The 55 papers included in the second volume are organized in topical sections on E-input/output devices (e-readers, whiteboards), facilitating social behaviour and collaboration, gaze-enabled interaction design, gesture and tactile user interfaces, gesture-based user interface design and interaction, health/medical devices, humans and robots, human-work interaction design, interface layout and data entry, learning and knowledge-sharing, learning tools, learning contexts, managing the UX, mobile interaction design, and mobile phone applications.
Download or read book Human Development and Interaction in the Age of Ubiquitous Technology written by Rahman, Hakikur and published by IGI Global. This book was released on 2016-06-27 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human condition is affected by numerous factors in modern society. In modern times, technology is so integrated into culture that it has become necessary to perform even daily functions. Human Development and Interaction in the Age of Ubiquitous Technology is an authoritative reference source for the latest scholarly research on the widespread integration of technological innovations around the globe and examines how human-computer interaction affects various aspects of people’s lives. Featuring emergent research from theoretical perspectives and case studies, this book is ideally designed for professionals, students, practitioners, and academicians.
Download or read book British Medical Journal written by and published by . This book was released on 1910 with total page 2236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Shock Waves written by Kazuyoshi Takayama and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shock wave research covers important inderdisciplinary areas which range from basic topics on gasdynamics, combustion and detonation, physico-chemistry of high temperature gases, plasma physics, astro and geophysics, materials science, astronautics and space technology to medical and industrial applications. This book includes 202 papers presented at the 18th the International Symposium on Shock Waves which describe the research frontier of shock wave phenopmena and 14 plenary lectures which show the state of the art of various fields of shock wave research. This proceedings is a unique collection of most important and updated shock wave research.
Download or read book Transportation Knowledge and Space in Urban and Regional Economics written by Kakuya Matsushima and published by Edward Elgar Publishing. This book was released on 2018 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of 16 original research chapters by international scholars addresses the complementary roles of transportation and knowledge and their spatial manifestations in modern urban and regional economies. The authors provide research from North America, Europe and Asia. While the studies employ sophisticated methods and theory, there is a strong element of practical applications and policy implications in each chapter as well. This book will be of interest to communities of research and practice in urban and regional economics and planning, regional science and economic geography, transportation research, planning and management and the knowledge economy.
Download or read book Reprints of Papers from the Science Laboratories of the University of Sydney written by and published by . This book was released on 1912 with total page 1022 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal and Proceedings of the Royal Society of New South Wales written by and published by . This book was released on 1910 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes list of members.
Download or read book Advanced Materials written by Ivan A. Parinov and published by Springer. This book was released on 2018-05-12 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents selected peer-reviewed contributions from the 2017 International Conference on “Physics and Mechanics of New Materials and Their Applications”, PHENMA 2017 (Jabalpur, India, 14–16 October, 2017), which is devoted to processing techniques, physics, mechanics, and applications of advanced materials. The book focuses on a wide spectrum of nanostructures, ferroelectric crystals, materials and composites as well as promising materials with special properties. It presents nanotechnology approaches, modern environmentally friendly piezoelectric and ferromagnetic techniques and physical and mechanical studies of the structural and physical–mechanical properties of materials. Various original mathematical and numerical methods are applied to the solution of different technological, mechanical and physical problems that are interesting from theoretical, modeling and experimental points of view. Further, the book highlights novel devices with high accuracy, longevity and extended capabilities to operate under wide temperature and pressure ranges and aggressive media, which show improved characteristics, thanks to the developed materials and composites, opening new possibilities for different physico-mechanical processes and phenomena.
