Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellents AI3 37135 and AI3 37156 and AI3 37157 1 2 3 6 Tetrahydro 1 2 Methyl 1 Oxopentyl Pyridine 1 1 Oxobutyl 4 Phenylmethyl Piperidine and 1 2 Methyl 1 Oxopropyl 4 Phenylmethyl Piperidine written by Allen W. Singer and published by . This book was released on 1980 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preliminary hazard evaluations of AI3-37135, AI3-37156, and AI3-37157 were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. The technical grade compounds did not cause any skin or sensitization reactions, and only mild corneal irritations. AI3-37135 and AI3-37156, however, caused phototoxic reactions, and were not approved for further testing. AI3-37157 did not cause such a reaction, was not acutely toxic by ingestion, and was approved for further testing as a candidate repellent. (Author).
Download or read book Technical Abstract Bulletin written by and published by . This book was released on 1980 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Government Reports Annual Index written by and published by . This book was released on 1980 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellents AI3 37221 and AI3 37225 1 3 cyclohexen 1 ylcarbonyl 3 methylpiperidine and 1 3 cyclohexen 1 ylcarbonyl 4 methylipiperazine written by Allen W. Singer and published by . This book was released on 1980 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preliminary hazard evaluations of AI3-37221 and AI3-37225 were performed by means of laboratory animal studies using rabbits and guinea pigs. Both technical grade compounds caused moderate corneal and conjunctival irritations. AI3-37221 caused mild primary skin irritation; AI3-37225 caused no such reaction. AI3-37225 was tested for skin sensitization and found to be negative. (Author).
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellents AI3 37220 1 3 Cyclohexen 1 Ylcarbonyl 2 Methylpiperidine and AI3 37224 1 3 Cyclohexen 1 Ylcarbonyl 1 2 3 6 Tetrahydropyridine written by Allen W. Singer and published by . This book was released on 1980 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preliminary hazard evaluations of AI3-37220 and AI3-37224 were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. The technical grade of compounds caused mild skin and eye irritation, but no phototoxic or sensitization reactions. Neither compound proved to be acutely toxic by ingestion. (Author).
Download or read book Government Reports Announcements Index written by and published by . This book was released on 1980 with total page 1284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36559 4 Methyl 1 2 Methylcyclohexyl Carbonyl Piperidine written by Maurice H. Weeks and published by . This book was released on 1977 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hazard evaluation of AI3-36559 was conducted using New Zealand White rabbits for skin and eye studies and Hartley guinea pigs for a skin sensitization study Technical grade compound caused in rabbits moderate eye injury. Ethanol solutions of AI3-36559 caused primary skin irritation and may be irritating to the skin of man.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36420 1 2 3 4 Tetrahydro 2 1 oxooctyl Isoquinoline written by Maurice H. Weeks and published by . This book was released on 1977 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: AI3-36420 was evaluated on New Zealand White rabbits for its potential to cause skin and eye irritation. The data obtained serves as a basis for making a recommendation concerning its potential use on humans.
Download or read book Topical Hazard Evaluation of Candidate Insect Repellent AI3 36368 Ga 1 2 3 4 Tetrahydro 1 2 Methyl 1 Oxobutyl Quinoline October 1975 July 1976 written by Maurice H. Weeks and published by . This book was released on 1976 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hazard evaluation of AI3-36368-Ga was conducted using New Zealand White rabbits for skin and eye studies; Hartley guinea pigs for a skin sensitization study; and Sprague-Dawley, Wistar-derived rats for determination of oral toxicity. It was recommended that AI-36368-Ga not be approved for further testing as a candidate insect repellent.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36560 2 Ethyl 1 2 Methylcyclohexyl Carbonyl Piperidine written by Maurice H. Weeks and published by . This book was released on 1977 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hazard evaluation of AI3-36560 was conducted using New Zealand White rabbits for skin and eye studies; Hartley guinea pigs for a skin sensitization study and Sprague-Dawley, Wistar-derived rats for determination of acute oral toxicity.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 35770 Hexahydro 1 2 Methylcyclohexyl Carbonyl 1 H Azepine written by R. D. Russell and published by . This book was released on 1985 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topical Hazard Evaluations of USDA Candidate Insect Repellent AI3-35770 were performed using New Zealand White rabbits, albino Hartley guinea pigs, and Sprague Dawley rats. Chemical AI3-35770 produced moderate to severe primary dermal irritation and necrosis in rabbits and guinea pigs. These effects were quantitatively worse in rabbits than in guinea pigs. This compound was moderately toxic to rats when given by the oral route.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36329a 1 6 Methyl 3 cyclohexen 1 yl carbonyl piperidine April 1978 June 1979 written by Allen W. Singer and published by . This book was released on 1979 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: A preliminary hazard evaluation of AI3-36329a was performed by means of laboratory animal studies using rats, rabbits and guinea pigs. The technical grade compound caused mild primary skin and eye irritation in rabbits, and produced a photoirritation reaction. It did not sensitize guinea pigs or prove to be acute ingestion hazard . Ethanol solutions of AI3-36329a also produced primary skin irritation. It was recommended that AI3-36329a 1-((6-Methyl-3-cyclohexen-1-y1) carbonl)-piperidine, not be approved for further testing. (Author).
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellents AI3 16734 1 11 78 Ga AI3 37519 AI3 37521 AI3 37529a AI3 37531a and AI3 37532a US Department of Agriculture Proprietary Compounds written by Allen W. Singer and published by . This book was released on 1980 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSECT REPELLENT COMPOUND AI3-16734-(1, 11, 78)-Ga was tested for primary irritation by application to clipped dorsal skin and to the eyes of New Zealand White rabbits. Although it was only mildly irritating to the skin, eye applications resulted in rapid systemic absorption and sudden generalized convulsions in both rabbits used, with one of the rabbits dying overnight. This response was also seen with a chemically related candidate repellent AI3-37528a (rejected September 1979). Five additional homologs of AI3-16734-(1, 11, 78)-Ga currently await testing. With the concurrence of the originator, the Organic Synthesis Laboratory, Beltsville Research Center, Department of Agriculture, all six related compounds are recommended for withdrawal from future consideration as candidate insect repellents. These are: (1) AI3-16734(1,11,78)-Ga, (2) AI3-37519, (3) AI3-37521, (4) AI3-37529a, (5) AI3-37531a, and (6) AI3-37532a.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36540 a 1 Cyclohexylcarbonyl 2 6 Dimethylpiperidine written by Maurice H. Weeks and published by . This book was released on 1977 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hazard evaluation of AI3-36540-a was conducted using New Zealand White rabbits for skin and eye studies; Hartley guinea pigs for a skin sensitization study; and Sprague-Dawley, Wistar-derived rats for determination of acute oral toxicity. AI3-36540-a is a potential sensitizing chemical. Technical grade compound produced severe injury to the cornea and to the conjunctiva of the rabbit and may cause similar damage if it should accidentally enter the eye of man. Ethanol solutions of this compound caused a photochemical skin irritation reaction in rabbits and may prove to be phototoxic on the skin of man.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellent AI3 36328 B 1 6 Methyl 3 Cyclohexen 1 YL Carbonyl Pyrrolidine Mar 1987 written by Maurice H. Weeks and published by . This book was released on 1987 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guidance for entomological testing of the Candidate Insect Repellent AI3-36328-b, 1-((6-methyl-3-cyclohexen-2-yl) carbonyl)pyrrolidine, irritation, skin, eye, toxic hazards, toxicity.
Download or read book Topical Hazard Evaluation Program of Candidate Insect Repellents AI3 34155 1 4 chlorophenoxy 2 2 methoxyethoxy ethane and AI3 34156 1 4 chlorophenoxy 2 2 ethoxyethoxy ethane written by Allen W. Singer and published by . This book was released on 1980 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preliminary hazard evaluations of AI3-34155 and AI3-34156 were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. The technical grade compounds did not cause skin, eye, or photo irritation. They did not prove to be skin sensitizers or to be acutely toxic by ingestion. It was recommended that both compounds be approved for further testing as candidate insect repellents. (Author).
Download or read book Topical Hazard Evaluation of Candidate Insect Repellent AI3 36558 3 Methyl 1 2 Methylcyclohexyl carbonyl Piperidine written by Maurice H. Weeks and published by . This book was released on 1977 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hazard evaluation of AI3-36558 was conducted using New Zealand White rabbits for skin and eye studies, Hartley guinea pigs for a skin sensitization study, and Sprague-Dawley, Wistar-derived rats for determination of oral toxicity. It was found that AI3-36558 is a potential sensitizing chemical. Technical grade compound produced moderate injury to the cornea and to the conjunctiva of the rabbit and may cause similar damage if it should accidentally enter the eye of man.
