Download or read book Therapy Approaches in Neurological Disorders written by Mario Bernardo-Filho and published by BoD – Books on Demand. This book was released on 2021-07-14 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurological disorders are conditions affecting the central or peripheral nervous system, with undesirable consequences for the quality of life. This book highlights and discusses several approaches for managing these conditions and improving the functional capacity and quality of life of patients, including whole-body vibration exercise, biofeedback, sagittal plane spine alignment, allopathic and non-allopathic medications, phytotherapy, and more.

Download or read book Gene Therapy for Neurological Disorders written by Fredric P. Manfredsson and published by Humana. This book was released on 2015-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

Download or read book Gene Therapy in Neurological Disorders written by Mingjie Li and published by Academic Press. This book was released on 2018-05-25 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Download or read book Handbook of Neurological Therapy written by Carlo Colosimo and published by Oxford University Press, USA. This book was released on 2015 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical book on neurological therapy. It is aimed at giving concise and updated answers to busy practicing clinicians in the clinic, ward, or emergency department. An evidence-based approach is used, but when there is no evidence or the data are inconclusive, an expert opinion is always given in order to meet the expectations of the reader. All neurological conditions, common and less common, are discussed; each chapter has a similar format, and contains an initial brief introduction on the epidemiology and clinical features of each disease. The therapy is then discussed, including pharmacological and non-pharmacological, with wide use of Tables & Figures. Flowcharts are also included in most of the chapters.

Download or read book Developing Multimodal Therapies for Brain Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-02-13 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.

Download or read book The Right Therapy for Neurological Disorders written by E. Beghi and published by Karger Medical and Scientific Publishers. This book was released on 2016-07-26 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Download or read book Translational Neuroscience written by Mark H. Tuszynski and published by Springer. This book was released on 2018-04-08 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.

Download or read book Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders written by Adeboye Adejare and published by Academic Press. This book was released on 2016-09-20 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource

Download or read book Handbook of Decision Support Systems for Neurological Disorders written by Hemanth D. Jude and published by Academic Press. This book was released on 2021-03-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Decision Support Systems for Neurological Disorders provides readers with complete coverage of advanced computer-aided diagnosis systems for neurological disorders. While computer-aided decision support systems for different medical imaging modalities are available, this is the first book to solely concentrate on decision support systems for neurological disorders. Due to the increase in the prevalence of diseases such as Alzheimer, Parkinson’s and Dementia, this book will have significant importance in the medical field. Topics discussed include recent computational approaches, different types of neurological disorders, deep convolution neural networks, generative adversarial networks, auto encoders, recurrent neural networks, and modified/hybrid artificial neural networks. Includes applications of computer intelligence and decision support systems for the diagnosis and analysis of a variety of neurological disorders Presents in-depth, technical coverage of computer-aided systems for tumor image classification, Alzheimer’s disease detection, dementia detection using deep belief neural networks, and morphological approaches for stroke detection Covers disease diagnosis for cerebral palsy using auto-encoder approaches, contrast enhancement for performance enhanced diagnosis systems, autism detection using fuzzy logic systems, and autism detection using generative adversarial networks Written by engineers to help engineers, computer scientists, researchers and clinicians understand the technology and applications of decision support systems for neurological disorders

Download or read book Disease Control Priorities Third Edition Volume 4 written by Vikram Patel and published by World Bank Publications. This book was released on 2016-03-10 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

Download or read book Overcoming Functional Neurological Symptoms A Five Areas Approach written by Christopher Williams and published by CRC Press. This book was released on 2011-08-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overcoming Functional Neurological Symptoms uses the proven and trusted five areas model of Cognitive Behaviour Therapy (CBT) to help people experiencing a range of medically unexplained symptoms, including chronic headaches, fatigue, dizziness, loss of sensation, weakness and numbness. Easy to use and practical, this CBT workbook: Presents the insights of award-winning authors who are experts in the field Contains therapeutic advice proven to work through years of research and practice Ensures patients success through specific plans leading to positive results Provides advice for friends and family of patients This book is designed for CBT practitioners, psychiatrists, psychologists, neurologists, physiotherapists, occupational therapists and healthcare workers to share with their patients. A linked and completely free online support course is located at www.livinglifetothefull.com with additional resources at www.fiveareas.com

Download or read book Functional Neurologic Disorders written by and published by Academic Press. This book was released on 2016-10-06 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies Fills an existing gap between traditional neurology and traditional psychiatry Contents include coverage of history, epidemiology, clinical presentations, and therapy Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available

Download or read book Occupational Therapy and Neurological Conditions written by Jenny Preston and published by John Wiley & Sons. This book was released on 2016-03-22 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: While diagnosis with a neurological condition may not be life-threatening, it can have significant impact on everyday life and on participation in activities. Occupational therapists must be able to fully consider the physical, cognitive, emotional, psychological and behavioural problems which may occur as a consequence of a neurological disorder, and understand the impact of diagnosis from a person-centred perspective. Occupational Therapy and Neurological Conditions incorporates theoretical, clinical and research evidence to support occupational therapists in the management of people with neurological conditions. Covers the key symptoms of neurological conditions and the biological basis of these within the ICF framework Provides an overview of therapy and management for all neurological conditions Includes key occupational therapy theory Case studies root concepts in real-life practice End-of-chapter self-evaluation questions help test understanding Occupational Therapy and Neurological Conditions is the ideal resource to support students, newly-qualified practitioners, and occupational therapists looking for an overview or introduction to this key area of practice.

Download or read book Behavioral Neurology Neuropsychiatry written by David B. Arciniegas and published by Cambridge University Press. This book was released on 2013-01-24 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.

Download or read book Neuronal Networks in Brain Function CNS Disorders and Therapeutics written by Carl Faingold and published by Academic Press. This book was released on 2013-12-26 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Download or read book Music Therapy and Music Based Interventions in Neurology written by Kerry Devlin and published by Springer Nature. This book was released on with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurogenic Dysphagia written by Tobias Warnecke and published by Springer Nature. This book was released on 2021-03-05 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a clinical manual that covers the whole spectrum of swallowing and its disorders. It starts with physiology of swallowing, pathophysiology of disordered deglutition, diagnostic methods (clinical and instrumental) and ends with an in-depth’s and up-to-date presentation of current treatment options. The clinically most relevant topics of dysphagia management on the stroke unit and the intensive care unit are dealt with in separate chapters. Also the closely intertwined issue of nutritional management is specifically addressed. Most importantly, the book covers all obligatory topics of the Flexible Endoscopic Evaluation of Swallowing (FEES)-curriculum, an educational initiative that started in Germany in 2014 and is currently being extended to other European and non-European countries. The book is richly illustrated and an online video section provides a number of typical patient cases. FEES is probably the most commonly chosen method for the objective assessment of swallowing and its disorders. It is used in stroke units, intensive care facilities, geriatric wards but also in rehabilitation clinics and within dedicated outpatient services. This book on neurogenic dysphagia therefore addresses a wide range of different medical disciplines, such as neurologists, geriatricians, intensive care physicians, rehabilitation physicians, gastroenterologists, otolaryngologists, phoniatrists and also speech-language pathologists.