Download or read book The Role of the Renin Angiotensin System in the Central Nervous System written by Natalia P. Rocha and published by Frontiers Media SA. This book was released on 2021-10-01 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Renin Angiotensin System written by J. Alan Johnson and published by Springer. This book was released on 2013-04-15 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourteenth Midwest Conference on Endocrinology and Metab olism, held at the University of Missouri - Columbia on September 28th and 29th, 1978, brought together several prominent researchers who are authorities on various aspects of the renin-angiotensin system. Each speaker presented an in-depth coverage of a topic related to his own area of expertise, including recent findings from his own research laboratory. Following each presentation thet:e was a general discussion of the material by the speaker and the audience. These presentations and the ensuing discussions are summarized in these published Proceedings. Traditionally the Midwest Conferences on Endocrinology and Metabolism have emphasized breadth as well as depth of coverage of the selected topic; the present Conference is no exception. Perusal of the titles of the presentations will reveal that the Conference dea1th with many different facets of the renin-angiotensin system, including the biochemistry, anatomy, physiology, and comparative endocrinology of this hormonal system, plus special areas of con sideration such as angiotensin receptors, angiotensin-converting enzyme, the control of renin release, angiotensin and aldosterone secretion, and the role of the renin-angiotensin system in the central nervous system. The selection of the renin-angiotensin system as the topic for the present conference was very timely because of the many noteworthy advances in this area in recent years, many by the participants in the Conference. The Editors are very appreciative of the excellent manuscripts which the speakers provided for these Proceedings.

Download or read book Central Nervous Control of Na Na Balance Relations to the Renin angiotensin System written by Werner Kaufmann and published by Thieme Medical Publishers. This book was released on 1976 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Central Actions of Angiotensin and Related Hormones written by Joseph P. Buckley and published by Elsevier. This book was released on 2013-10-22 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central Actions of Angiotensin and Related Hormones investigates the centrally mediated actions of angiotensin and related hormones in the central nervous system (CNS). Topics covered include angiotensin I converting enzyme activity in the choroid plexus and in the retina; peptide regulation of neuronal excitability; effects of angiotensin-II and angiotensin-III on catecholamine biosynthesis; and humoral kidney mediation of adrenal catecholamine response to hemorrhage. A systems analysis of CNS-angiotensin interaction is also presented. This book is comprised of 51 chapters and opens with a discussion on the results of initial studies undertaken at the University of Pittsburgh to probe the centrally mediated hypertensive response of angiotensin II. The following chapters explore angiotensin receptor sites and angiotensin antagonists, along with the mechanisms involved in changes of blood pressure elicited by hypothalamic stimulation. The effects of angiotensin-II and angiotensin-III on the biosynthesis of catecholamines are also analyzed. The last chapter looks at recommendations regarding the nomenclature of the renin-angiotensin system, especially with respect to the extrarenal tissue enzymes. This monograph will be a valuable source of information for biochemists, biologists, physiologists, and pharmacologists.

Download or read book The Renin Angiotensin System in the Brain written by and published by . This book was released on 1982 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetics Neurology Behavior and Diet in Parkinson s Disease written by Colin R Martin and published by Academic Press. This book was released on 2020-08-13 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Download or read book Neural Control of Renal Function Second Edition written by Ulla C. Kopp and published by Biota Publishing. This book was released on 2018-07-17 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.

Download or read book Cellular and Molecular Biology of the Renin Angiotensin System written by Mohan K. Raizada and published by CRC Press. This book was released on 2018-01-18 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Biology of the Renin-Angiotensin System provides the first review and update of the state-of-the-art cellular and molecular aspects of the renin-angiotensin system. The book presents detailed analyses from world experts on each component of this system, including future directions. Topics range from angiotensin II receptor subtypes to processing of renin to the use of transgenic animal models for studying the role of this system in hypertension. Cellular and Molecular Biology of the Renin-Angiotensin System is essential reading for physiologists of the renin-angiotensin system, endocrinologists, cardiovascular specialists, renal physiologists, and neurobiologists.

Download or read book The Protective Arm of the Renin Angiotensin System RAS written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

Download or read book Renin Angiotensin Aldosterone System written by Samy I. McFarlane and published by BoD – Books on Demand. This book was released on 2021-11-24 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Renin-Angiotensin Aldosterone System (RAAS) plays an important role not only in salt and water homeostasis but also in the cardiovascular system, the kidney, and the brain. While several volumes address different aspects of the RAAS function, this book provides cutting-edge information on the pathogenesis of various disorders related to RAAS overactivation. It also presents unique aspects of RAAS functioning that have not been sufficiently described in the literature. Topics covered include assessment of hypoaldosteronism in infancy, RASS and cognitive decline, and the role of RAAS in the pathogenesis of COVID-19. Written by experts in the field in an easy-to-follow and illustrated format, this volume will benefit students and practitioners, as well as clinical and basic science investigators alike.

Download or read book Drugs Enzymes and Receptors of the Renin Angiotensin System written by Ahsan Husain and published by CRC Press. This book was released on 2000-02-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and unique feature of this book is that a commentary on each chapter, written by an independent peer or peers, is included to present alternative views, greater depth and a different perspective. Clinicians and researchers alike will find this volume a stimulating, and perhaps even entertaining, addition to their libraries. .

Download or read book Neurobiology of Body Fluid Homeostasis written by Laurival Antonio De Luca Jr. and published by CRC Press. This book was released on 2013-10-01 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration. Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume: Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure The book highlights research conducted by leading scientists on signal transduction and sensory afferent mechanisms, molecular genetics, perinatal and adult long-term influences on regulation, central neural integrative circuitry, and autonomic/neuroendocrine effector systems. The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake. A unique reference on the neurobiology of body fluid homeostasis, this volume is certain to fuel additional research and stimulate further debate on the topic.

Download or read book Frontiers in Hypertension Research written by J. H. Laragh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: reached full definition in the 1940s by Kempner diet. The important role of adrenal aldosterone and associates in demonstrating the beneficial ef secretion in supporting human hypertension is now fects of a low salt rice diet for treating hypertensive well recognized as are the beneficial effects of patients. It became apparent that the value of rice blockade, especially in low-renin patients who ex was wholly related to its sodium content. A rice hibit inappropriate or absolute excesses of aldoste diet, or any other stringent low sodium diet, rone secretion. Further definition of the more sub greatly improves or completely corrects the hyper tle participation of aldosterone and of the factors tension of about ~ or so of all patients with essen that control aldosterone secretion in hypertensive subjects are promising areas for further research. tial hypertension. However, what is often forgotten is that little or no benefit accrues to the remaining THE NERVOUS SYSTEM majority of patients. Parallel studies of animal models has demon Besides the endocrine and excretory functions of strated the amplifying effect of a high sodium diet the kidney and the influence of dietary sodium on blood pressure and vice versa. Strains of rats and of aldosterone secretion, there has been long were developed which are especially sensitive to standing agreement about the important role of the pressor effects of a high sodium diet. In a way, the nervous system in blood pressure control.

Download or read book Textbook of Nephro Endocrinology written by Ajay K. Singh and published by Academic Press. This book was released on 2009-01-12 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field

Download or read book Aldosterone Mineralocorticoid Receptor written by Brian Harvey and published by BoD – Books on Demand. This book was released on 2019-09-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.

Download or read book Selected Chapters from the Renin Angiotensin System written by Aleksandar Kibel and published by BoD – Books on Demand. This book was released on 2020-08-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.

Download or read book The Nervous System and the Heart written by Gert J. Ter Horst and published by Springer Science & Business Media. This book was released on 2000 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are physiological bases for associations of the heart with emotions, and with the apparently universal increased mortality in winter. Thirteen contributions integrate expertise in cardiology and neuroscience in overviewing the latest knowledge about head-heart interactions. The first five chapters explain autonomic control of cardiovascular functions, the neural supply of the heart, and neuropathology. Part II examines the effects of stress on the hypothalamo-pituitary-adrenal system and the heart. Part III treats the neurobiology and neuroimaging of cardiac pain. Next, humoral factors in cardiovascular regulation and as mediators of inflammation in coronary artery disease are considered. Finally, the relationship between heart disease and cognitive/neuropsychiatric disorders is discussed. Includes photomicrographs, schematic drawings, and nice large print.