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Book The New Regular Pancreatic Cancer Diet

Download or read book The New Regular Pancreatic Cancer Diet written by Dr Laura Antonio and published by Independently Published. This book was released on 2023-09-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the brand-new pancreatic cancer diet book "The Pancreatic Cancer Diet Guide," we set out on a quest for healing and empowerment for individuals battling the powerful foe known as pancreatic cancer. This thorough and sympathetic book provides crucial information on how diet can play a crucial part in maintaining and improving the quality of life throughout pancreatic cancer treatment, offering a lifeline to sufferers and their loved ones. Although pancreatic cancer brings particular difficulties, this book gives you the information and resources you need to overcome them. "The new pancreatic cancer diet" demystifies the complex relationship between food, cancer, and wellbeing. It was written by experts in oncology nutrition and was informed by the most recent research. What you'll find there is a thorough understanding of the nutritional requirements and effects of pancreatic cancer on the body. Practical advice for dealing with typical symptoms include nausea, exhaustion, and weight loss. An abundance of mouthwatering and simple-to-make recipes designed to satisfy the nutritional requirements of people with pancreatic cancer. information on the effectiveness of particular foods and supplements in promoting healing and recovery. Advice for preserving emotional and psychological health while traveling. This book focuses on thriving in the midst of hardship rather than merely surviving. During pancreatic cancer therapy, "the new pancreatic cancer diet" provides encouragement, a road plan, and hope for a happier, more rewarding life. This invaluable tool will enable you to make knowledgeable nutritional decisions that can significantly alter your health, whether you're a patient, caregiver, or healthcare professional. Unleash nutrition's healing potential and set off on a life-changing path towards greater health and "the new pancreatic cancer diet."

Book Pancreatic Cancer Diet Cookbook

Download or read book Pancreatic Cancer Diet Cookbook written by Nelson Collins and published by Independently Published. This book was released on 2023-12-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PREVIEW Pancreatic cancer occurs when cells in your pancreas mutate (change) and multiply out of control, forming a tumor. Your pancreas is a gland in your abdomen (belly), between your spine and stomach. It makes hormones that control blood-sugar levels and enzymes that aid in digestion. Most pancreatic cancers start in the ducts of your pancreas. The main pancreatic duct (the duct of Wirsung) connects your pancreas to your common bile duct. Early-stage pancreatic tumors don't show up on imaging tests. For this reason, many people don't receive a diagnosis until the cancer has spread (metastasis). Pancreatic cancer is also resistant to many common cancer drugs, making it notoriously difficult to treat. Ongoing research focuses on early detection through genetic testing and new imaging methods. Still, there's much to learn. The pancreas secretes enzymes that aid digestion and hormones that help regulate the metabolism of sugars. This type of cancer is often detected late, spreads rapidly and has a poor prognosis. There are no symptoms in the early stages. Later stages are associated with symptoms, but these can be non-specific, such as lack of appetite and weight loss. Treatment may include surgically removing the pancreas, radiation and chemotherapy. Pancreatic cancer is responsible for approximately 3% of all cancers in the United States. It's the 10th most common cancer in men and people assigned male at birth, and the 8th most common cancer in women and people assigned female at birth. Pancreatic tumors are either exocrine or neuroendocrine (endocrine) tumors. This is based on the type of cell they start in. Knowing the type of tumor is important because each type acts differently and responds to different treatments. More than 90% of pancreatic cancers are exocrine tumors. The most common type of pancreatic cancer is adenocarcinoma. Less than 10% of pancreatic tumors are neuroendocrine tumors (pancreatic NETs or PNETs), also called islet cell tumors. They often grow slower than exocrine tumors. Changes in your DNA cause cancer. These can be inherited from your parents or can arise over time. The changes that arise over time can happen because you were exposed to something harmful. They can also happen randomly. Pancreatic cancer's exact causes are not well understood. About 10% of pancreatic cancers are considered familial or hereditary. Most pancreatic cancer happens randomly or is caused by things such as smoking, obesity and age. If you are a first-degree relative of someone diagnosed with pancreatic cancer, you may have an increased risk of developing pancreatic cancer. Your family member with pancreatic cancer is strongly recommended to undergo genetic testing for inherited mutations. Get a Copy Now!

Book Understanding Pancreatic Cancer

Download or read book Understanding Pancreatic Cancer written by and published by . This book was released on 2015 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Battling Pancreas Cancer with Nutrition

Download or read book Battling Pancreas Cancer with Nutrition written by April Davis and published by . This book was released on 2013-04-22 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: [This] is a handbook written with clear guidance for patients during their fight with pancreatic cancer. ... The cancer can inhibit your body's ability to heal, decrease your energy, and decrease your immune system. By optimizing diet and nutrition, research has shown that outcomes of surgery, radiation, and chemotherapy are improved.--Page [4] of cover.

Book Ultimate Pancreatic Cancer Diet Cookbook

Download or read book Ultimate Pancreatic Cancer Diet Cookbook written by Mazimum C Jerri and published by . This book was released on 2021-06-13 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: We recognize that quality of life is important for all of us but is certainly much more of a challenge for individuals and their loved ones trying to manage chronic illness. Pancreatic cancer generally has a poor prognosis, and therefore prevention plays a crucial role in the battle against this serious disease. In this Diet Cookbook, you will find a collection of recipes and meal ideas that is aimed at providing people living with pancreatic cancer and their caregivers with a wide range of flavorful recipes - including recipes for breakfast, lunch, dinner, appetizers, sides, desserts, and beverages as well as holiday and seasonal tips - to make preparing healthy, and memorable dishes for any meal of the day easier. For patients with pancreatic disease, there are many times when it is difficult to eat at all. Even when you are feeling well, you still have to be very careful to follow a low-fat diet. This book shares some guidelines, and, as always, your doctor is the best one to tell you how to eat. Note that sometimes it is easier to eat small meals several times a day, instead of trying to sit down to three big meals

Book Pancreatic Cancer Diet Cookbook for Beginners

Download or read book Pancreatic Cancer Diet Cookbook for Beginners written by Lisa William and published by Independently Published. This book was released on 2024-01-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Empowering Wellness Through Wholesome Recipes: A Practical Guide for Pancreatic Cancer Patients With Healthy Nutrition and Easy To Prepare Diet Welcome to "Nourishing Hope," a heartfelt guide designed to empower individuals navigating the challenging journey of pancreatic cancer. Embark on a culinary journey tailored for resilience and recovery with our cookbook designed to meet the unique needs of individuals facing pancreatic cancer. In "The Pancreatic Cancer Diet Cookbook for Beginners," we present a carefully curated collection of recipes that go beyond mere nourishment - they are a source of empowerment, comfort, and joy. Diverse and Delectable Recipes: - Discover a treasure trove of various recipes thoughtfully categorized to provide variety and simplicity. From nutrient-packed breakfast bowls to comforting soups, flavorful mains, and delightful desserts, each recipe is a testament to the belief that delicious meals can be a powerful ally in the fight against pancreatic cancer. Nutritional Guidance for Healing: - Navigate the complexities of pancreatic cancer with a comprehensive introduction that sheds light on the role of nutrition in treatment. Learn how specific ingredients can address symptoms, enhance well-being, and promote overall health. This cookbook is not just a compilation of recipes; it's a guide to fostering a positive and mindful relationship with food. Soothing Herbal Teas and Beverages: - Ease the challenges of treatment with our dedicated section on comforting herbal teas and nutrient-rich beverages. From ginger-infused concoctions to calming chamomile blends, these beverages offer solace and hydration during the pancreatic cancer journey. Beginner-Friendly Approach: - Designed with beginners in mind, our cookbook transforms the kitchen into a space of empowerment. Step-by-step instructions, easily accessible ingredients, and practical tips ensure that even novice cooks can create meals that nourish the body and soul. Holistic Wellness: - Embrace a holistic approach to healing that extends beyond the plate. This cookbook encourages mindfulness, resilience, and a positive mindset, fostering a sense of well-being throughout the pancreatic cancer treatment journey. A Beacon of Hope: - "The Pancreatic Cancer Diet Cookbook for Beginners" is not just a cookbook; it's a beacon of hope. As a cookbook, it has resonated with individuals, caregivers, and healthcare professionals alike, offering a ray of positivity and practicality in the face of pancreatic cancer. Join the Culinary Journey: - Embark on a culinary journey that transcends the ordinary. "The Pancreatic Cancer Diet Cookbook for Beginners" is more than a cookbook; it's a testament to the strength of the human spirit and the healing power of nourishing meals. With each page, discover the art of thriving through the art of cooking. Unlock the potential of your kitchen, nourish your body, and thrive on the path to healing. "The Pancreatic Cancer Diet Cookbook for Beginners" is more than a cookbook; it's a celebration of life, flavor, and the resilience that resides within us all. Become a part of the "The Pancreatic Cancer Diet Cookbook for Beginners" community - where wellness and culinary delight converge. So what are you waiting for? Order your copy today!

Book Premium Pancreatic Cancer Diet Guide

Download or read book Premium Pancreatic Cancer Diet Guide written by Zara Dawson and published by Independently Published. This book was released on 2023-10-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the ultimate resource for managing pancreatic cancer with our comprehensive Pancreatic Cancer Diet Guide. This indispensable guide is designed to support and empower those facing the challenges of pancreatic cancer by providing expert advice, detailed meal plans, and vital nutritional information. Our mission is to help you or your loved one maintain the best possible quality of life during this difficult journey. We understand the unique dietary requirements that pancreatic cancer presents, and we've created a tailored resource to address them. With this guide, you'll gain access to a wealth of information and support to make informed decisions regarding your diet and overall well-being. Key Features & Benefits: EXPERT GUIDANCE: Access the expertise of nutritionists, doctors, and cancer specialists to navigate your pancreatic cancer journey effectively. TAILORED MEAL PLANS: Receive personalized meal plans designed to meet the specific nutritional needs of pancreatic cancer patients. NUTRITIONAL INSIGHTS: Gain a deep understanding of the role nutrition plays in managing pancreatic cancer and maintaining overall health. EASY-TO-FOLLOW RECIPES: Explore a variety of delicious, easy-to-prepare recipes that are gentle on the pancreas. DIETARY TIPS: Learn essential dietary strategies for symptom management, digestion support, and maintaining energy levels. LIFESTYLE SUPPORT: Discover how to adapt your lifestyle to improve your quality of life during treatment and recovery. EMPOWERING RESOURCES: Equip yourself with knowledge, confidence, and a supportive community to face pancreatic cancer with strength. Bullet Points: Expert Guidance for Pancreatic Cancer Nutrition - Stay informed and supported throughout your journey. Tailored Meal Plans for Optimal Nutrition - Personalized diets to address your specific needs. Nutritional Insights for Pancreatic Cancer - Understand the role of nutrition in your well-being. Delicious & Gentle Recipes - Enjoy tasty meals that won't strain your pancreas. Dietary Tips for Symptom Management - Learn strategies for easing discomfort. Lifestyle Adaptations for Quality of Life - Make positive changes to boost your well-being. Empowering Resources & Community - Find strength and support during your battle.

Book Everything about Pancreatic Cancer Diet

Download or read book Everything about Pancreatic Cancer Diet written by Walton Uselton and published by Independently Published. This book was released on 2024-06-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the essential guide to managing pancreatic cancer through diet with "Everything About Pancreatic Cancer Diet." This comprehensive book offers a deep dive into the dietary strategies crucial for patients undergoing treatment or in remission. Authored by experts in oncology nutrition, this book blends scientific insights with practical advice, ensuring every reader gains a thorough understanding of how nutrition impacts pancreatic cancer outcomes. Inside, you'll uncover detailed explanations on how specific foods and nutrients can influence cancer progression and overall health. Learn about the role of antioxidants, vitamins, and minerals in supporting immune function and combating oxidative stress. Explore personalized dietary approaches tailored to different stages of pancreatic cancer, empowering readers to make informed choices that complement medical treatments. Beyond nutrition, "Everything About Pancreatic Cancer Diet" addresses common challenges such as maintaining weight, managing symptoms, and improving quality of life through dietary modifications. Whether you're a patient, caregiver, or healthcare professional, this book equips you with the knowledge to navigate nutritional complexities with confidence. Practical tips and meal plans are included to simplify grocery shopping and meal preparation, making it easier to implement dietary changes effectively. Evidence-based recommendations are reinforced by real-life patient success stories, illustrating the transformative impact of diet on pancreatic cancer management. Empower yourself or your loved ones with the knowledge to optimize health outcomes and enhance well-being throughout the cancer journey. "Everything About Pancreatic Cancer Diet" is your indispensable resource for navigating the intersection of nutrition and pancreatic cancer care. Take charge of your health today with "Everything About Pancreatic Cancer Diet" - the definitive guide to leveraging diet for better outcomes in pancreatic cancer treatment and survivorship.

Book The Pancreatic Cancer Diet Cookbook

Download or read book The Pancreatic Cancer Diet Cookbook written by Jethro Clifford and published by Independently Published. This book was released on 2024-01-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Embark on a culinary journey that transcends nourishment and becomes a source of compassionate care with 'Balancing Flavor and Wellness: A Culinary Companion for Pancreatic Cancer Patients and Caregivers.' This cookbook is more than a collection of recipes; it is a heartfelt endeavor, weaving together the artistry of culinary creations and the profound care required by those facing the challenges of pancreatic cancer.In the introduction, you're welcomed into a world where each recipe is a gesture of love and support-a tapestry carefully crafted to bring not just sustenance but also an abundance of flavor to those navigating the intricate journey of pancreatic cancer. Authored by Jethro Clifford, this culinary companion stands as a guiding light, offering a beacon of hope through the healing potential found within the realm of nutrition.The cookbook unfolds like a narrative of resilience, acknowledging the complexities of pancreatic cancer while emphasizing the role of nutrition in supporting overall well-being. 'Balancing Flavor and Wellness' is a testament to the intertwining of nourishment and pleasure-a recognition that each bite can be a source of comfort and strength in the face of adversity.Chapter by chapter, the cookbook guides you through a gastronomic exploration tailored to address the unique dietary needs and challenges faced by pancreatic cancer patients and their caregivers. 'Gastronomic Resilience' lays the foundation, delving into the nutritional intricacies that form the bedrock of recipes. Here, food is not just sustenance; it becomes a testament to the body's adaptability and rejuvenation.'Nutrient Symphony' orchestrates a harmonious blend of flavors, textures, and culinary artistry, carefully crafted to create a nourishing and delightful ensemble for those facing pancreatic cancer. The metaphor of a symphony embodies the idea that each ingredient plays a unique role, contributing to the overall composition of a nutrient-rich diet."Healing Infusions" unfolds as a soothing oasis, presenting nourishing beverages designed to bring comfort and vitality. This chapter recognizes the profound impact beverages can have on well-being, offering not only hydration but a symphony of flavors and healing properties tailored to support those navigating pancreatic cancer and their caregivers."Culinary Comforts" forms the heart of the cookbook-a celebration of nurturing power found in well-cooked meals. The essence lies not only in the nutritional value of the recipes but in the emotional resonance of each dish. Comfort food becomes a source of solace, a moment of respite, and a gesture of care for those on the challenging journey of pancreatic cancer.'Savoring Joy' concludes the culinary exploration, not as a mere conclusion but as a vibrant celebration-a testament to the transformative power of joy infused into the culinary experience. This final chapter invites you to savor not just the flavors but the emotional resonance infused into each dish, fostering joy, creativity, and emotional well-being.The conclusion of 'Balancing Flavor and Wellness' invites reflection on the nourishing wisdom embedded in every dish. It's not just a cookbook; it's a source of inspiration, comfort, and a flavorful guide as you navigate the unique and wondrous path through pancreatic cancer. Here's to the culmination of this culinary companion-a toast to the journey, the flavors, and the enduring spirit that 'Balancing Flavor and Wellness' brings to the table."

Book The Heterogeneity of Cancer Metabolism

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Book Pancreatic Cancer

    Book Details:
  • Author : Howard Reber
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 1461218101
  • Pages : 553 pages

Download or read book Pancreatic Cancer written by Howard Reber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i

Book Clinical Pancreatology for Practising Gastroenterologists and Surgeons

Download or read book Clinical Pancreatology for Practising Gastroenterologists and Surgeons written by Juan Enrique Dominguez-Munoz and published by John Wiley & Sons. This book was released on 2021-03-17 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.

Book Current Trends in Cancer Management

Download or read book Current Trends in Cancer Management written by Liliana Streba and published by BoD – Books on Demand. This book was released on 2019-09-25 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cancer diagnosis, prognosis, and treatment is constantly advancing. From novel biomarkers to cutting-edge imaging solutions, changing chemotherapy protocols and novel immune-targeting agents, medical teams develop and test new ways to manage this ever-growing threat to the modern age. Imaging has been a reliable method for initial diagnosis and later surveillance of premalignant and cancerous lesions of the digestive tract. This book project aims to characterize the main diagnostic procedures and novel medical and surgical treatments, as well as provide an updated view on current guidelines, premalignant lesions management, and minimally invasive curative techniques.

Book The Cancer fighting Kitchen

Download or read book The Cancer fighting Kitchen written by Rebecca Katz and published by Random House LLC. This book was released on 2009 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides dozens of recipes formulated for the specific nutritional and appetite needs of cancer patients, sharing step-by-step instructions for nutritionally preparing for chemotherapy, radiation, and a full range of treatment phases.

Book AJCC Cancer Staging Manual

    Book Details:
  • Author : Frederick L, Greene
  • Publisher : Springer Science & Business Media
  • Release : 2013-11-21
  • ISBN : 1475736568
  • Pages : 386 pages

Download or read book AJCC Cancer Staging Manual written by Frederick L, Greene and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

Book Diet Nutrition And Cancer

    Book Details:
  • Author : National Research Council
  • Publisher : Legare Street Press
  • Release : 2022-10-27
  • ISBN : 9781015691629
  • Pages : 0 pages

Download or read book Diet Nutrition And Cancer written by National Research Council and published by Legare Street Press. This book was released on 2022-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Book Theranostic Approach for Pancreatic Cancer

Download or read book Theranostic Approach for Pancreatic Cancer written by Ganji Purnachandra Nagaraju and published by Academic Press. This book was released on 2020-01-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. This book discusses several topics related to pancreatic cancer such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer Discusses treatment options available currently as well as prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment