Download or read book The Major Discoveries of Cajal and His Disciples Consolidated Milestones for the Neuroscience of the XXIst Century written by Fernando de Castro and published by Frontiers Media SA. This book was released on 2017-04-25 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Santiago Ramón y Cajal started to unravel the fine structure of the nervous system in the last decades of the XIXth century maybe only his unbeatable soul of brave Spaniard imagined that most of the descriptions were scientific truths that lasted to date. Simple histological stainings, curiosity to ameliorate these, monocular microscopes, patience for drawing his observations and a rich imaginative open mind: this is the recipy for Cajal success. His descriptions of connectivity in the nervous system, compiled in Cajal's opus magna published in 1904 ("Textura del sistema nervioso del hombre y los vertebrados") and 1911 ("Histologie du systeme nerveux"), have been corroborated by modern techniques decade after decade. Even more, the main hypothesis that Cajal raised are universally recognised as biological laws, today: the neuron theory, the law on the dynamic polarization of the neuron and the chemotropic hypothesis. That is: the nervous system is not a sincitial network but is formed by individual cells; the transmission of the nerve impulses follow a main direction within a given neuron; the axons are guided by chemical substances in a chemotropic way, till form synapses with their targets. Attracted by Cajal's strong personality and scientific success, a number of medical students and doctors join him in the crusade to explore the nervous system. And the seed planted by the universal savant was really successful: Francisco Tello described interesting aspects of the regeneration of peripheral nerves which are very useful for neuroscientist currently working in this topic; Nicolás Achúcarro significantly contributed to study neuroglia and future microglia; Pío del Río-Hortega identified two out of the four main nervous cell types, the oligodendrocytes and microglia, and proposed an almost still valid classification for the CNS tumours; Fernando de Castro made was the first description of arterial chemoreceptors in the carotid body; Rafael Lorente de Nó was a dominant figure of Neuroscience for decades after the IInd World War, first describing the columnar organization of the cerebral cortex well before Mountcastle, Hubbel and Wiesel. Even less recognised co-workers and disciples of Cajal (his brother Pedro Ramón y Cajal, Domingo Sánchez, the neurologist Rodríguez-Lafora... protagonised discoveries that are consolidated scientific truths today). Altogether, it is difficult (if not impossible) to find a school in biology contributing in such a fundamental and variated way to the common acervo like the collectively known as Cajal School or Spanish Neurological School. Although the particular way to work of the Maestro, selecting a pleiade of brilliant collaborators with whom accomplish such a titanic feat, giving them freedom for their studies, has been recognised and confronted to antagonic systems followed by other relevant scientists and scientific schools, the general recognition of such a significant major milestones for Neuroscience and their vigency in the well-marched XXIst century is not: this is the purpose of this Ebook, to remind all these examples of how successful can be the scientific work when it is minutious, constant and performed by brilliant, imaginative and skilled scientists with a minimal conditions supporting their efforts.
Download or read book Neural Networks written by Ranjodh Singh Dhaliwal and published by U of Minnesota Press. This book was released on 2024-04-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical examination of the figure of the neural network as it mediates neuroscientific and computational discourses and technical practices Neural Networks proposes to reconstruct situated practices, social histories, mediating techniques, and ontological assumptions that inform the computational project of the same name. If so-called machine learning comprises a statistical approach to pattern extraction, then neural networks can be defined as a biologically inspired model that relies on probabilistically weighted neuron-like units to identify such patterns. Far from signaling the ultimate convergence of human and machine intelligence, however, neural networks highlight the technologization of neurophysiology that characterizes virtually all strands of neuroscientific and AI research of the past century. Taking this traffic as its starting point, this volume explores how cognition came to be constructed as essentially computational in nature, to the point of underwriting a technologized view of human biology, psychology, and sociability, and how countermovements provide resources for thinking otherwise.
Download or read book The Arterial Chemoreceptors written by Yoshiaki Hayashida and published by Springer Science & Business Media. This book was released on 2006-04-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.
Download or read book Never resting microglia physiological roles in the healthy brain and pathological implications written by Amanda Sierra and published by Frontiers E-books. This book was released on 2015-02-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a wide range of detrimental effects. In the last few years, a series of discoveries have challenged the current view of microglia, showing their active and positive contribution to normal brain function. This Research Topic reviewed the novel physiological roles of microglia in the developing, mature and aging brain, under non-pathological conditions. In particular, this Research Topic discussed the cellular and molecular mechanisms by which microglia contribute to the formation, pruning and plasticity of synapses; the regulation of adult neurogenesis as well as hippocampal learning and memory; among other important roles. Because these novel findings defy our understanding of microglial function in health as much as in disease, this Research Topic also summarized the current view of microglial nomenclature, phenotypes, origin and differentiation, and contribution to various brain pathologies. Additionally, novel imaging approaches and molecular tools to study microglia in their non-activated state have been discussed. In conclusion, this Research Topic seeked to emphasize how the current research in neuroscience is challenged by never-resting microglia.
Download or read book The Neuroscience of Psychotherapy Healing the Social Brain Second Edition written by Louis Cozolino and published by W. W. Norton & Company. This book was released on 2010-06-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the brain's architecture is related to the problems, passions, and aspirations of human beings. In contrast to this view, recent theoretical advances in brain imaging have revealed that the brain is an organ continually built and re-built by one's experience. We are now beginning to learn that many forms of psychotherapy, developed in the absence of any scientific understanding of the brain, are supported by neuroscientific findings. In fact, it could be argued that to be an effective psychotherapist these days it is essential to have some basic understanding of neuroscience. Louis Cozolino's The Neuroscience of Psychotherapy, Second Edition is the perfect place to start. In a beautifully written and accessible synthesis, Cozolino illustrates how the brain's architecture is related to the problems, passions, and aspirations of human beings. As the book so elegantly argues, all forms of psychotherapy--from psychoanalysis to behavioral interventions--are successful to the extent to which they enhance change in relevant neural circuits. Beginning with an overview of the intersecting fields of neuroscience and psychotherapy, this book delves into the brain's inner workings, from basic neuronal building blocks to complex systems of memory, language, and the organization of experience. It continues by explaining the development and organization of the healthy brain and the unhealthy brain. Common problems such as anxiety, trauma, and codependency are discussed from a scientific and clinical perspective. Throughout the book, the science behind the brain's working is applied to day-to-day experience and clinical practice. Written for psychotherapists and others interested in the relationship between brain and behavior, this book encourages us to consider the brain when attempting to understand human development, mental illness, and psychological health. Fully and thoroughly updated with the many neuroscientific developments that have happened in the eight years since the publication of the first edition, this revision to the bestselling book belongs on the shelf of all practitioners.
Download or read book The Beautiful Brain written by Larry W. Swanson and published by Abrams. This book was released on 2017-01-17 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the crossroads of art and science, Beautiful Brain presents Nobel Laureate Santiago Ramón y Cajal’s contributions to neuroscience through his groundbreaking artistic brain imagery. Santiago Ramón y Cajal (1852–1934) was the father of modern neuroscience and an exceptional artist. He devoted his life to the anatomy of the brain, the body’s most complex and mysterious organ. His superhuman feats of visualization, based on fanatically precise techniques and countless hours at the microscope, resulted in some of the most remarkable illustrations in the history of science. Beautiful Brain presents a selection of his exquisite drawings of brain cells, brain regions, and neural circuits with accessible descriptive commentary. These drawings are explored from multiple perspectives: Larry W. Swanson describes Cajal’s contributions to neuroscience; Lyndel King and Eric Himmel explore his artistic roots and achievement; Eric A. Newman provides commentary on the drawings; and Janet M. Dubinsky describes contemporary neuroscience imaging techniques. This book is the companion to a traveling exhibition opening at the Weisman Art Museum in Minneapolis in February 2017, marking the first time that many of these works, which are housed at the Instituto Cajal in Madrid, have been seen outside of Spain. Beautiful Brain showcases Cajal’s contributions to neuroscience, explores his artistic roots and achievement, and looks at his work in relation to contemporary neuroscience imaging, appealing to general readers and professionals alike.
Download or read book The Shallows written by Nicholas Carr and published by . This book was released on 2020-09-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 10th-anniversary edition of this landmark investigation into how the Internet is dramatically changing how we think, remember and interact, with a new afterword.
Download or read book Python in Neuroscience written by Eilif Muller and published by Frontiers Media SA. This book was released on 2015-07-23 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Python is rapidly becoming the de facto standard language for systems integration. Python has a large user and developer-base external to theneuroscience community, and a vast module library that facilitates rapid and maintainable development of complex and intricate systems. In this Research Topic, we highlight recent efforts to develop Python modules for the domain of neuroscience software and neuroinformatics: - simulators and simulator interfaces - data collection and analysis - sharing, re-use, storage and databasing of models and data - stimulus generation - parameter search and optimization - visualization - VLSI hardware interfacing. Moreover, we seek to provide a representative overview of existing mature Python modules for neuroscience and neuroinformatics, to demonstrate a critical mass and show that Python is an appropriate choice of interpreter interface for future neuroscience software development.
Download or read book Neural Plasticity and Regeneration written by F.J. Seil and published by . This book was released on 2000-10-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: While a cure for spinal cord injury remains elusive, the contents of this volume convey a sense of progress towards this goal. More has been learned about the primary and secondary consequences of spinal cord injury and more is being understood about recovery mechanisms that are intrinsic to the nervous system and that might be further encouraged. Expanding the control capacity of uninjured portions of the nervous system may be one approach to improving the functional capabilities of those afflicted with this disorder. New therapies in the form of transplantable cells that can encourage growth or myelination or prevent secondary damage or that can substitute for injured cells appear promising for future applications. Genetic and tissue engineering studies give us further hope, and under continuous development are novel drugs with greater specificity and fewer detrimental effects and improved delivery methods for such drugs. The volume is organized into six topic sections, including I) Strategies for Spinal Cord Injury Repair, II) Plasticity of the Injured Spinal Cord: Retraining Neural Circuits to Promote Motor Recovery, III) Impact of Neuroprosthetic Applications on Functional Recovery, IV) Neurotrophins and Activity-Dependent Plasticity, V) Candidate Cells for Transplantation into the Injured CNS and VI) New Directions in Regeneration Research. Both clinical and experimental animal studies are presented in the first three sections, while predominantly basic research is the focus of the second half of the book.
Download or read book Psychology written by Miles Hewstone and published by BPS Blackwell. This book was released on 2005-06-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychology, published in association with the British Psychological Society, is the definitive introductory textbook for students starting their study of psychology. written with style and authority by more than 20 leading psychologists from the UK and Australasia, in association with our editorial team; contains comprehensive and integrated coverage of all the major topics in first-year undergraduate psychology; also provides extensive treatment of cutting-edge applied areas such as health, organizational and forensic psychology; each chapter helps students to understand psychology on their own terms: 'Research Close-ups' bring research to life via snapshot case studies; 'Everyday Psychology' boxes apply real-life contexts to the basic principles; includes a host of additional useful features, from chapter maps, learning objectives, expert opinions and profiles of pioneering psychologists in each subfield, to chapter summaries, revision questions, suggestions for further reading and a glossary; supported by an interactive website containing a multiple choice testbank, essay questions, practice questions, downloadable figures and tables, electronic chapters and lecture-by-lecture instructor support. Visit www.bpsblackwell.co.uk/hewstone for more information.
Download or read book Cajal and De Castro s Neurohistological Methods written by Miguel A. Merchán and published by Oxford University Press. This book was released on 2016 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cajal and De Castro's Neurohistological Methods provides the first English translation of Fernando de Castro's 1933 publication "Elementos de T cnica Microgr fica del Sistema Nervioso." A student of the famed founder of modern neuroscience, with Santiago Ramon y Cajal also serving as the Editor of the original text, Fernando de Castro recorded all the various protocols that had been used in his laboratory by his students in order to provide a manual of histological procedures specifically designed for the fine structure of the nervous system. This renowned text is virtually unknown in its original form outside the Spanish-speaking world. In a text that reads like a mix between a recipe book and an alchemical manuscript, authors Miguel Merchan, Javier DeFelipe, and Fernando de Castro (descendant of the 1933 publication's author) put the new translation into historical context. This book is also beautifully illustrated with plates of histological techniques, provides a quick guide to new vocabulary, and the author's notes on the translated text. This pivotal work of classic neurohistological techniques is a wonderful addition to the Cajal library.
Download or read book Rio Hortega s Third Contribution to the Morphological Knowledge and Functional Interpretation of the Oligodendroglia written by Jose R. Iglesias-Rozas and published by Newnes. This book was released on 2013-06-05 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pío del Rio-Hortega, one of the pioneering neuroscientists and discoverer of microglia, has been recognized as one of the most important Spanish neurohistogists of the past century. His landmark research on oligodendroglia, originally published in Spanish in 1928, has been translated into English for the first time by Dr. José R. Iglesias-Rozas and Prof. Manuel Garrosa. The book establishes definitively the concept of oligodendroglia and describes in great detail its structure, varieties, function, origin and pathology, providing a thorough review. The entire 1928 writing is presented, including the 79 excellent drawings and photographs from the original publication. To complement the original book and provide historical context, the translators have also included an introduction to the research and a biography of Pío del Rio-Hortega. This book constitutes a milestone in the history of neuroscience, biology and medicine, and it will be valuable reading for researchers and practitioners in these fields. - First English translation of seminal 1928 research - Contains the broad descriptions and interpretations of the normal and pathological oligodendroglia - Full original text and new introductory sections
Download or read book Recollections of My Life written by Santiago Ramón y Cajal and published by . This book was released on 1966 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Political Epistemology written by Pietro Daniel Omodeo and published by Springer Nature. This book was released on 2019-10-14 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an investigation of the ideological dimensions of the disciplinary discourses on science in line with the scholarly tradition of historical epistemology. It offers a programmatic treatment of the political-epistemological problematic along three entangled lines of inquiry: socio-historical, epistemological and historiographical. The book aims for a meta-level integration of the existing scholarship on the social and cultural history of science in order to consider the ways in which struggles for hegemony have constantly informed scientific discourses. This problematic is of primary relevance for scholars in Science Studies, philosophers, historians and sociologists of science, but would also be relevant for anybody interested in scientific culture and political theory.
Download or read book A Study of Nerve Physiology written by Rafael Lorente de Nó and published by . This book was released on 1947 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vacation Stories written by Santiago Ramón y Cajal and published by University of Illinois Press. This book was released on 2001 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world-famous neurobiologist, Santiago Ramn y Cajal won the Nobel Prize for his scientific research in 1906. The previous year, he published these stories: five ingenious tales that take a microscopic look at the nature, allure, and danger of scientific curiosity. Ramn y Cajal waited almost twenty years to publish these stories because he feared they would compromise his scientific career. Featuring the cutting-edge science of the mid-1880s (microscopy, bacteriology, and hypnosis), they probe the seductive power that proceeds from scientific knowledge and explore how the pursuit of such knowledge alternately redeems and ensnares humanity. Here revenge is disguised as research and common fraud as moral purification. Critical thought vies with moribund tradition and stifling religion for a hold on the human spirit; rigid divisions of class and wealth dissolve before the indiscriminate assault of microbes. One man's faith in science gives him the tools to outwit superstition and win the true love and happiness for which he has sacrificed. that melds the epiphany of A Christmas Carol with the macabre detail of an Edgar Allan Poe story.Now available for the first time in English, Ramn y Cajal's stories reveal a great deal about human nature and the collusion of ambition and greed that prey on the hapless and thoughtless, whether in the name of science, religion, or the state. Laura Otis, whose dual background in literature and science echoes that of the author, has crafted a sparkling translation that captures the wit and imagination of the original.
Download or read book Cajal s Neuronal Forest written by Javier DeFelipe and published by Oxford University Press. This book was released on 2018 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection contains hundreds of beautiful rarely-seen-before figures produced throughout the nineteenth century and the beginning of the twentieth century by famed father-of-modern-neuroscience Santiago Ramón y Cajal (1852-1934) and his contemporaries. Cajal was captivated by the beautiful shapes of the cells of the nervous system. He and his fellow scientists saw neurons as trees and glial cells as bushes. Given their high density and arrangement, neurons and glial resembled a thick forest, a seemingly impenetrable terrain of interacting cells mediating cognition and behavior.
