Download or read book The Gene Ontology Handbook written by Christophe Dessimoz and published by Humana. This book was released on 2018-06-23 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system.
Download or read book Gene Ontology A Resource for Analysis and Interpretation of Biological Database written by Paige Hill and published by . This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gene ontology (GO) is a bioinformatics project which aims to merge the representation of gene and characteristics of gene product in all species. It is a thorough and updated compilation of biological information that is utilized as a resource for computational representation of the most recent scientific data available concerning coding as well as non-coding functions of genes. High-throughput biological datasets can be interpreted and analyzed using the GO resource. The goal of the GO analysis is to pinpoint the molecular functions, biological processes and cellular locations of the genes. It utilizes markup language in order to make the genetic data and curated attributes of gene products readable by machine, in a manner which is integrated across all species. This book provides comprehensive insights on gene ontology. It aims to shed light on some of the unexplored aspects of this subject. Those in search of information to further their knowledge will be greatly assisted by this book.
Download or read book Biological Knowledge Discovery Handbook written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2015-02-04 with total page 1126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive overview of preprocessing, mining, and postprocessing of biological data Molecular biology is undergoing exponential growth in both the volume and complexity of biological data and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD) providing in-depth fundamental and technical field information on the most important topics encountered. Written by top experts, Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data covers the three main phases of knowledge discovery (data preprocessing, data processing also known as data mining and data postprocessing) and analyzes both verification systems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological Data Mining Combining sound theory with practical applications in molecular biology, Biological Knowledge Discovery Handbook is ideal for courses in bioinformatics and biological KDD as well as for practitioners and professional researchers in computer science, life science, and mathematics.
Download or read book Regulation of Gene Expression by Small RNAs written by Rajesh K. Gaur and published by CRC Press. This book was released on 2009-04-27 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
Download or read book Handbook Of Metadata Semantics And Ontologies written by Sicilia Miguel-angel and published by World Scientific. This book was released on 2013-12-17 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.
Download or read book A Handbook of Gene and Cell Therapy written by Clévio Nóbrega and published by Springer Nature. This book was released on 2020-06-27 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases
Download or read book Applied Ontology written by Katherine Munn and published by Walter de Gruyter. This book was released on 2013-05-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called ‘ontologies,’ for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who created them, and unable to serve as inputs for automated reasoning. This volume shows, in a non-technical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends.
Download or read book Pattern Recognition and Machine Intelligence written by Bhabesh Deka and published by Springer Nature. This book was released on 2019-11-25 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set of LNCS 11941 and 11942 constitutes the refereed proceedings of the 8th International Conference on Pattern Recognition and Machine Intelligence, PReMI 2019, held in Tezpur, India, in December 2019. The 131 revised full papers presented were carefully reviewed and selected from 341 submissions. They are organized in topical sections named: Pattern Recognition; Machine Learning; Deep Learning; Soft and Evolutionary Computing; Image Processing; Medical Image Processing; Bioinformatics and Biomedical Signal Processing; Information Retrieval; Remote Sensing; Signal and Video Processing; and Smart and Intelligent Sensors.
Download or read book The Semantic Web ISWC 2005 written by Yolanda Gil and published by Springer Science & Business Media. This book was released on 2005-11-04 with total page 1095 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th International Semantic Web Conference, ISWC 2005, held in Galway, Ireland, in November 2005. The 54 revised full academic papers and 17 revised industrial papers presented together with abstracts of 3 invited talks were carefully reviewed and selected from a total of 217 submitted papers to the academic track and 30 to the industrial track. The research papers address all current issues in the field of the semantic Web, ranging from theoretical aspects to various applications. The industrial track contains papers on applications in particular industrical sectors, new technology for building applications, and methodological and feasibility aspects of building industrical applications that incorporate semantic Web technology. Short descriptions of the top five winning applications submitted to the Semantic Web Challenge competition conclude the volume.
Download or read book The Text Mining Handbook written by Ronen Feldman and published by Cambridge University Press. This book was released on 2007 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher description
Download or read book The Handbook of Genetics Society written by Paul Atkinson and published by Routledge. This book was released on 2009-07-02 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative Handbook which offers a discussion of the social, political, ethical and economic consequences and implications of the new bio-sciences. The Handbook takes an interdisciplinary approach providing a synoptic overview of contemporary international social science research on genetics, genomics and the new life sciences. It brings together leading scholars with expertise across a wide-ranging spectrum of research fields related to the production, use, commercialisation and regulation of genetics knowledge. The Handbook is structured into seven cross-cutting themes in contemporary social science research on genetics with introductions written by internationally renowned section editors who take an interdisciplinary approach to offer fresh insights on recent developments and issues in often controversial fields of study. The Handbook explores local and global issues and critically approaches a wide range of public and policy questions, providing an invaluable reference source to a wide variety of researchers, academics and policy makers.
Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.
Download or read book Principles of Data Integration written by AnHai Doan and published by Elsevier. This book was released on 2012-06-25 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Data Integration is the first comprehensive textbook of data integration, covering theoretical principles and implementation issues as well as current challenges raised by the semantic web and cloud computing. The book offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand. Readers will also learn how to build their own algorithms and implement their own data integration application. Written by three of the most respected experts in the field, this book provides an extensive introduction to the theory and concepts underlying today's data integration techniques, with detailed, instruction for their application using concrete examples throughout to explain the concepts. This text is an ideal resource for database practitioners in industry, including data warehouse engineers, database system designers, data architects/enterprise architects, database researchers, statisticians, and data analysts; students in data analytics and knowledge discovery; and other data professionals working at the R&D and implementation levels. Offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand Enables you to build your own algorithms and implement your own data integration applications
Download or read book Prediction of Protein Structures Functions and Interactions written by Janusz M. Bujnicki and published by John Wiley & Sons. This book was released on 2008-12-23 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and cellular component) and discussed in the light of their contribution to the emerging field of systems biology. Topics covered include: first steps of protein sequence analysis and structure prediction automated prediction of protein function from sequence template-based prediction of three-dimensional protein structures: fold-recognition and comparative modelling template-free prediction of three-dimensional protein structures quality assessment of protein models prediction of molecular interactions: from small ligands to large protein complexes macromolecular docking integrating prediction of structure, function, and interactions Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local installation. It is an essential guide to the newest, best methods for prediction of protein structure and functions, for researchers and advanced students working in structural bioinformatics, protein chemistry, structural biology and drug discovery.
Download or read book Ontology Based Information Retrieval for Healthcare Systems written by Vishal Jain and published by John Wiley & Sons. This book was released on 2020-07-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation
Download or read book Genomic Signal Processing and Statistics written by Edward R. Dougherty and published by Hindawi Publishing Corporation. This book was released on 2005 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.
