Download or read book Test No 111 Hydrolysis as a Function of PH written by Organisation for Economic Co-operation and Development and published by . This book was released on 2004 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 - 9). This Guideline is designed as a tiered approach; each tier is triggered by the results of the previous tier. Sterile aqueous buffer solutions of different pH values (pH 4, 7 and 9) are treated with the non-labelled or labelled test substance (only one concentration, which should not exceed 0.01 M or half of the saturation concentration). They are incubated in the dark under controlled laboratory conditions (at constant temperatures). After appropriate time intervals, buffer solutions are analysed for the test substance and for hydrolysis products. The preliminary test should be carried out for 5 days at 50 ± 0.5°C and pH 4.0, 7.0 and 9.0. The second tier consists of the hydrolysis of unstable substances, and the third tier is the identification of hydrolysis products. The higher Tier tests should be conducted until 90 % hydrolysis of the test substance is observed or for 30 days whichever comes first.

Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 111 Hydrolysis as a Function of pH written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 320 Determining Anaerobic Transformation of Chemicals in Liquid Manure written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a standardised method to examine the transformation of chemicals in pig and cattle liquid manure under anaerobic conditions.

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319B Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub cellular fraction RT S9 written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes RT HEP written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 305 Bioaccumulation in Fish Aqueous and Dietary Exposure written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 318 Dispersion Stability of Nanomaterials in Simulated Environmental Media written by OECD and published by OECD Publishing. This book was released on 2017-10-09 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: This test guideline describes a test procedure to gain information on dispersion stability of manufactured nanomaterials in simulated environmental media. The main purpose of this guideline is to assess the ability of a nanomaterial to attain a colloidal dispersion and to conserve this ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 123 Partition Coefficient 1 Octanol Water Slow Stirring Method written by OECD and published by OECD Publishing. This book was released on 2006-07-11 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 314 Simulation Tests to Assess the Biodegradability of Chemicals Discharged in Wastewater written by OECD and published by OECD Publishing. This book was released on 2008-10-16 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method to assess the extent and kinetics of primary and ultimate biodegradation of organic chemicals whose route of entry into the environment begins with their discharge to wastewater. It consists of five simulation ...

Download or read book Persistent Bioaccumulative and Toxic PBT Chemicals written by Adam D. K. Abelkop and published by CRC Press. This book was released on 2018-10-08 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.

Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Guidance Document on the Use of the Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to how the system will work.

Download or read book OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices GIVIMP written by OECD and published by OECD Publishing. This book was released on 2018-12-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...

Download or read book OECD Guidelines for the Testing of Chemicals OECD Series on Testing and Assessment Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures written by OECD and published by OECD Publishing. This book was released on 2002-05-10 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document sets out the objectives, organisational context, and plan for a Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures.

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 316 Phototransformation of Chemicals in Water Direct Photolysis written by OECD and published by OECD Publishing. This book was released on 2008-10-16 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test guideline describes studies on phototransformation in water to determine the potential effects of solar irradiation on chemicals in surface water, considering direct photolysis only. It is designed as a tiered approach. The Tier 1 is based ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 5 Test No 507 Nature of the Pesticide Residues in Processed Commodities High Temperature Hydrolysis written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method conducted as model studies to predict the degradation pathway of the active ingredient under hydrolytic conditions, to identify the degradation products, and to determine the relative amount of degradation ...

Download or read book Code of Federal Regulations written by and published by . This book was released on 2002 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Special edition of the Federal Register, containing a codification of documents of general applicability and future effect ... with ancillaries.

Download or read book Code of Federal Regulations Title 40 Protection of Environment Pt 790 999 Revised as of July 1 2011 written by and published by Government Printing Office. This book was released on 2011-08-29 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: