Download or read book Synthesis Structure and Reactivity of Electrophilic Ruthenium Complexes Containing the n5 C5 CH3 5 Ru NO Core written by Geun-Bae Yi and published by . This book was released on 1995 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1996 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ruthenium Chemistry written by Ajay Kumar Mishra and published by CRC Press. This book was released on 2018-01-17 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will describe Ruthenium complexes as chemotherapeutic agent specifically at tumor site. It has been the most challenging task in the area of cancer therapy. Nanoparticles are now emerging as the most effective alternative to traditional chemotherapeutic approach. Nanoparticles have been shown to be useful in this respect. However, in view of organ system complicacies, instead of using nanoparticles as a delivery tool, it will be more appropriate to synthesize a drug of nanoparticle size that can use blood transport mechanism to reach the tumor site and regress cancer. Due to less toxicity and effective bio-distribution, ruthenium (Ru) complexes are of much current interest. Additionally, lumiscent Ru-complexes can be synthesized in nanoparticle size and can be directly traced at tissue level. The book will contain the synthesis, characterization, and applications of various Ruthenium complexes as chemotherapeutic agents. The book will also cover the introduction to chemotherapy, classification of Ru- complexes with respect to their oxidation states and geometry, Ruthenium complexes of nano size: shape and binding- selectivity, binding of ruthenium complexes with DNA, DNA cleavage studies and cytotoxicity. The present book will be more beneficial to researchers, scientists and biomedical. Current book will empower specially to younger generation to create a new world of ruthenium chemistry in material science as well as in medicines. This book will be also beneficial to national/international research laboratories, and academia with interest in the area of coordination chemistry more especially to the Ruthenium compounds and its applications.
Download or read book Synthesis and Reactivity of Compounds Containing Ruthenium carbon nitrogen and oxygen Bonds written by and published by . This book was released on 1990 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The products and mechanisms of the thermal reactions of several complexes of the general structure (PMe3)4Ru(X)(Y) and (DMPM)2Ru(X)(Y) where X and Y are hydride, aryl, and benzyl groups, have been investigated. The mechanism of decomposition depends critically on the structure of the complex and the medium in which the thermolysis is carried out. The alkyl hydride complexes are do not react with alkane solvent, but undergo C-H activation processes with aromatic solvents by several different mechanisms. Thermolysis of (PMe3)4Ru(Ph)(Me) or (PMe3)4Ru(Ph)2 leads to the ruthenium benzyne complex (PMe3)4Ru([eta]2-C6H4) (1) by a mechanism which involves reversible dissociation of phosphine. In many ways its chemistry is analogous to that of early rather than late organo transition metal complexes. The synthesis, structure, variable temperature NMR spectroscopy and reactivity of ruthenium complexes containing aryloxide or arylamide ligands are reported. These complexes undergo cleavage of a P-C bond in coordinated trimethylphosphine, insertion of CO and CO2 and hydrogenolysis. Mechanistic studies on these reactions are described. The generation of a series of reactive ruthenium complexes of the general formula (PMe3)4Ru(R)(enolate) is reported. Most of these enolates have been shown to bind to the ruthenium center through the oxygen atom. Two of the enolate complexes 8 and 9 exist in equilibrium between the O- and C-bound forms. The reactions of these compounds are reported, including reactions to form oxygen-containing metallacycles. The structure and reactivity of these ruthenium metallacycles is reported, including their thermal chemistry and reactivity toward protic acids, electrophiles, carbon monoxide, hydrogen and trimethylsilane. 243 refs., 10 tabs.
Download or read book Ruthenium Complexes written by Alvin A. Holder and published by John Wiley & Sons. This book was released on 2018-02-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by a team of highly respected researchers combining their expertise in chemistry, physics, and medicine, this book focuses on the use of rutheniumcontaining complexes in artificial photosynthesis and medicine. Following a brief introduction to the basic coordination chemistry of ruthenium complexes and their synthesis in section one, as well as their photophysical and photochemical properties, the authors discuss in detail the major concepts of artificial photosynthesis and mechanisms of hydrogen production and water oxidation with ruthenium in section two. The third section of the text covers biological properties and important medical applications of ruthenium complexes as therapeutic agents or in diagnostic imaging. Aimed at stimulating research in this active field, this is an invaluable information source for researchers in academia, health research institutes and governmental departments working in the field of organometallic chemistry, green and sustainable chemistry as well as medicine/drug discovery, while equally serving as a useful reference also for scientists in industry.
Download or read book Ruthenium in Organic Synthesis written by Shun-Ichi Murahashi and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive book, one of the leading experts, Shun-Ichi Murahashi, presents all the important facets of modern synthetic chemistry using Ruthenium, ranging from hydrogenation to metathesis. In 14 contributions, written by an international authorship, readers will find all the information they need about this fascinating and extraordinary chemistry. The result is a high quality information source and a indispensable reading for everyone working in organometallic chemistry. From the contents: Introduction (S.-I. Murahashi) Hydrogenation and Transfer Hydrogenation (M. Kitamura and R. Noyori) Oxidations (S.-I. Murahashi and N. Komiya) Carbon-Carbon Bond Formations via Ruthenacycle Intermediates (K. Itoh) Carbon-Carbon Bond Formation via pi-Allylruthenium Intermediates (T. Mitsudo) Olefin Metathesis (R. H. Grubbs) Cyclopropanation (H. Nishiyama) Nucleophilic Addition to Alkynes and Reactions via Vinylidene Intermediates (P. Dixneuf) Reactions via C-H Activation (N. Chatani) Lewis Acid Reactions (E. P. Kundig) Reactions with CO and CO2 (T. Mitsudo) Isomerization of Organic Substrates Catalyzed by Ruthenium Complexes (H. Suzuki) Radical Reactions (H. Nagashima) Bond Cleavage Reactions (S. Komiya)
Download or read book The Chemistry of Ruthenium written by E.A. Seddon and published by Elsevier. This book was released on 2013-10-22 with total page 1414 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Ruthenium is concerned with the chemistry of ruthenium, with emphasis on synthesis and structure. The discussion spans a wide range of fields, from coordination chemistry and organometallic chemistry to structural chemistry (of both molecular and extended lattices), electrochemistry and photochemistry, as well as kinetics and spectroscopy. Comprised of 15 chapters, this book begins with an introduction to the discovery and early history of ruthenium, along with its extraction and purification, isotopes, physical and chemical properties, and applications. The discussion then turns to the concept of oxidation state and a scheme for systematizing descriptive inorganic chemistry together with its applicability to ruthenium chemistry. Subsequent chapters focus on the chemistry of ruthenium(VIII), ruthenium(VII), ruthenium(VI), ruthenium(V), ruthenium(IV), ruthenium(III), ruthenium(II), ruthenium(I), and ruthenium(0). The book also considers ruthenium carbonyl clusters and nitrosyls before concluding with a review of the photophysics and photochemistry of tris(diimine)ruthenium(II) complexes. This monograph will be useful to students, practitioners, and researchers in the field of inorganic chemistry, as well as those who are interested in the chemistry of ruthenium.
Download or read book Synthesis and Reactivity of Ruthenium Phosphine Complexes Containing Metal carbon and Metal heteroatom Bonds written by Melinda Jane Burn and published by Ann Arbor, Mich. : University Microfilms International. This book was released on 1993 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Trans bis alkynyl Ruthenium Complexes written by Samantha Grace Eaves and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This Thesis describes the synthesis and characterisation of a series of trans-bis(alkynyl) ruthenium complexes, trans-[Ru(C?CR)2(L)4], to better understand how the variation of the metal ancillary ligands (L) affect electronic structure and spectroscopic properties, chemical reactivity, and behaviour in metal|molecule|metal junctions. Reactions of cis-[RuCl2(dppm)2] with terminal alkyne HC?CC6H4-4-R, in the presence of TlBF4 and base, gives into trans-bis(alkynyl) complexes, trans-[Ru(C?CC6H4-4-R)2(dppm)2], for electron withdrawing R groups or cationic ?3-butenynyl complexes, E-[Ru(?3-{HC(C6H4-4-R)=CC?C(C6H4-4-R)})(dppm)2]+ for electron donating R groups. Reactions of cis-[RuCl2(dppm)2] with di-terminal alkynes HC?CC6H4-2,5-X2-4-C?CH, in the presence of TlBF4 and [NnBu4]Cl, gives trans-[RuCl(C?CC6H2-2,5-X2-4-CCl=CH2)(dppm)2], inferring a quinoidal cumulene intermediate. Multi-metallic trans-bis(alkynyl) {Ru(dppe)2} complexes, varying in binding groups and bridging ligands, have been prepared. Reversible oxidation processes, whilst corresponding to the number of integrated metal centres, exhibit a high degree of alkynyl character in all cases. The vibrational and electronic spectra of both neutral and oxidised complexes are complicated by the presence of numerous spectroscopically distinct rotamer conformations and redox isomers. For example in the case of mono-oxidised complexes, a principal low-energy (?-?*) NIR band is exhibited along with multiple higher energy (MLCT-type) NIR bands, which can be assigned by comparison with smaller model systems. Finally, trans-bis(alkynyl) {Ru{P(OEt)3}4} complexes have been synthesised. As a result of the increased (pseudo D4h) molecular symmetry and consequent fewer distinct rotamer conformations, a lesser number of NIR bands are exhibited for trans-[Ru(C?CR)2{P(OEt)3}4]+ than bis-chelating dppm and dppe derivatives. Between trans-[Ru(C?CR)2(PP?)] (PP? = (dppe)2, {P(OEt)3}4) complexes, the {Ru(dppe)2} derivatives give rise to conductance histograms with additional features. These features are attributed to contacts formed at or across the dppe-phenyl rings, leading to suggestions that phosphite complexes might be novel ï¿1⁄2insulated? molecular wires.
Download or read book Ruthenium N Heterocyclic Carbene and Ruthenium Acetylide Complexes Supported by Macrocyclic Porphyrin Or Tetradentate Schiff Base Ligands written by Ka-Ho Chan and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Ruthenium-N-heterocyclic Carbene and Ruthenium Acetylide Complexes Supported by Macrocyclic Porphyrin or Tetradentate Schiff Base Ligands: Synthesis, Structure and Catalytic Applications" by Ka-ho, Chan, 陳嘉豪, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled RUTHENIUM-N-HETEROCYCLIC CARBENE AND RUTHENIUM ACETYLIDE COMPLEXES SUPPORTED BY MACROCYCLIC PORPHYRIN OR TETRADENTATE SCHIFF BASE LIGANDS: SYNTHESIS, STRUCTURE AND CATALYTIC APPLICATIONS Submitted by Chan Ka Ho for the degree of Doctor of Philosophy at The University of Hong Kong in March 2015 Transition metal-catalyzed C-C and C-N bond formation reactions are important transformations in synthetic organic chemistry. In the endeavor of this thesis to develop robust/versatile catalysts for these reactions, the trans effect imposed by N-heterocyclic carbene (NHC) and acetylide ligand onto ruthenium complexes supported by macrocyclic porphyrin or tetradentate Schiff-base ligands was studied. The catalytic activity of these novel ruthenium complexes towards carbene and/or nitrene transfer and insertion reactions was also explored. II A series of bis(NHC)ruthenium(II) porphyrin complexes [Ru (Por)(NHC) ] were synthesized by deprotonation of imidazolium salt using a strong base. These complexes displayed unprecedentedly high catalytic activity towards carbene/nitrene transfer and insertion reactions, including alkene cyclopropanation and aziridination, carbene C-H, S-H, N-H and O-H insertions, and nitrene C-H insertion with product -1 turnover frequency up to 1950 min . Carbene modification of N-terminus of peptide o II at 37 C was achieved. Chiral [Ru (D -Por)(NHC) ] catalyst led to highly 4 2 enantioselective carbene/nitrene transfer and insertion reactions with up to 98% ee. DFT calculations revealed that the strong σ-donor strength of trans axial NHC ligand stabilizes the formation of metal-carbene and metal-nitrene intermediate from decomposition of diazo compounds and organic azides, which is crucial for the transition metal-catalyzed oxidative C-C and C-N bond formation reactions to proceed under mild reaction conditions. II A series of ruthenium Schiff-base complexes cis-β-[Ru (Schiff-base)(CO) ] were synthesized and characterized. These complexes showed high catalytic activity towards enantioselective cyclopropanation, carbene C-H and Si-H bond insertions. II t The cis-[Ru (2-CPh -4- Bu-Schiff-base)(CO) ]-catalyzed intermolecular 3 2 cyclopropanation of styrene with EDA in CH Cl afforded desired cyclopropane 2 2 product in 90% isolated yield and 95% ee with a product turnover number of 9000. Excellent trans- and high enantioselectivity were observed with wide substrate scope, including conjugated, electron-rich, electron-deficient and aliphatic terminal alkenes. Carbene C-H and Si-H insertion reactions proceeded smoothly with II t cis-[Ru (2-CPh -4- Bu-Schiff-base)(CO) ] as catalyst, giving the desired products in 3 2 82-97% yields with excellent enantioselectivity (up to 99% ee). The same complex was also catalytically active towards intramolecular cyclopropanation and intramolecular alkyl carbene sp C-H bond insertion to give cis-products with up to 99:1 cis: trans ratio and with excellent enantioselectivities (up to 98% ee). DFT calculations on the intermolecular cyclopropanation catalyzed by II cis-β-[Ru (Schiff-base)(CO) ] revealed that among the ruthenium-carbene intermediates possibly involved in the reactions, the cis-β species are more stable than their trans isomer with
Download or read book Synthesis Reactivity and Characterization of Ruthenium Complexes Containing a Single Bipyridine Ligand written by Simon I. Barsoum and published by . This book was released on 1989 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Electronic Structure Investigation of Ruthenium Complexes Containing Novel Redox active Ligands written by Fabian Ehret and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ruthenium Complexes with Non innocent Quinonoid Quinoline 5 8 dione and Iminoquinone Ligands written by Hari Sankar Das and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mononuclear Arene Ruthenium Complexes Containing 5 6 diphenyl 3 pyridine 2 yl 1 2 4 triazine as Chelating Ligand Synthesis and Molecular Structure written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Water soluble Arene Ruthenium Complexes Containing Pyridinethiolato Ligands Synthesis Molecular Structure Redox Properties and Anticancer Activity of the Cations sup 6 sup arene Ru i p i SC sub 5 sub H sub 4 sub NH sub 3 sub sup 2 sup written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Reactivity of Ruthenium Hydride Complexes Containing Chelating Triphosphines and Studies on Ruthenium Chloride Acetate and Carbonyl Complexes Containing Chelating Triphosphines written by Guochen Jia and published by . This book was released on 1989 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis Structure and Reactivity of Chiral Cyclopentadienyl Ruthenium II Complexes written by D. M. Wong and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
