Download or read book SPIONs as Nano Theranostics Agents written by Atefeh Zarepour and published by Springer. This book was released on 2017-01-20 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.
Download or read book Magnetic Nanoheterostructures written by Surender Kumar Sharma and published by Springer Nature. This book was released on 2020-03-02 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.
Download or read book Nanotheranostics written by Mahendra Rai and published by Springer Nature. This book was released on 2019-11-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.
Download or read book Nanotheranostics For Personalized Medicine written by Patrick Couvreur and published by World Scientific. This book was released on 2016-02-22 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.
Download or read book Magnetic Nanoparticles in Human Health and Medicine written by Costica Caizer and published by John Wiley & Sons. This book was released on 2021-09-08 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.
Download or read book Cancer Nanotechnology written by and published by Academic Press. This book was released on 2018-06-23 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike
Download or read book Nanotheranostics for Personalized Medicine written by Simona Mura and published by World Scientific. This book was released on 2016 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome. Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine. This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field."--Provided by publisher
Download or read book Magnetic Nanoparticles for Targeted Cancer Theranostics written by Zachary R. Stephen and published by . This book was released on 2016 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has given scientists new tools for the development of advanced materials for the detection, diagnosis and treatment of disease. Superparamagnetic iron oxide nanoparticles (SPIONs) in particular have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents due to a combination of favorable superparamagnetic properties, biodegradability, and surface properties that allow modification for improved in vivo kinetics and multifunctionality. SPIONs favorable characteristics have further led to their investigation as promising theranostic agents, which combine imaging and therapeutic capabilities in a single nanovector. The combination of imaging and therapy could allow for real-time monitoring of drug delivery and the tailoring of treatment for individual patients with the promise of improved clinical outcomes for patients suffering from cancers such as glioblastoma (GBM). This dissertation is intended to address limitation of conventional clinical cancer treatment including current cancer targeting limitations and poor pharmacokinetic of hydrophobic chemotherapeutics that lead to unacceptable side effects. First, SPIONs were coated with cross-linked, redox-responsive copolymers composed of chitosan and polyethylene glycol (PEG), functionalized with cancer targeting agent chlorotoxin (CTX), and modified with O6-benzylguanine (BG), an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor to improve temozolomide based treatments of GBMs. It was found that CED of the BG loaded SPION were more tolerable than free drug and increased survival 3-fold over untreated animals in an intracranial GBM mouse model. Next, analogs of BG were evaluated for their inhibitory efficacy and modified to allow for polymerization on the SPION surface via hydrazone linkages to facilitate improved drug loading and controlled drug release. Finally, a new synthesis and functionalization strategy for theranostic agents is presented that demonstrated streamlined production, allowed for great control over the display of functional moieties on the SPION surface, increased batch to batch consistency, and provided improved magnetic properties.
Download or read book Handbook of Nanomaterials for Cancer Theranostics written by Joao Conde and published by Elsevier. This book was released on 2018-06-27 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments
Download or read book Multifunctional And Targeted Theranostic Nanomedicines written by Keerti Jain and published by Springer Nature. This book was released on 2023-08-23 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use.
Download or read book Gd Doped Superparamagnetic Magnetite Nanoparticles for Potential Cancer Theranostics written by Maheshika Palihawadana-Arachchige and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has facilitated the applications of a class of nanomaterials called superparamagnetic iron oxide nanoparticles (SPIONs) in cancer theranostics. This is a new discipline in biomedicine that combines therapy and diagnosis in one platform. The multifunctional SPIONs, which are capable of detecting, visualizing, and destroying the neoplastic cells with fewer side effects than the conventional therapies, are reviewed in this chapter for theranostic applications. The chapter summarizes the design parameters such as size, shape, coating, and target ligand functionalization of SPIONs, which enhance their ability to diagnose and treat cancer. The review discusses the methods of synthesizing SPIONs, their structural, morphological, and magnetic properties that are important for theranostics. The applications of SPIONs for drug delivery, magnetic resonance imaging, and magnetic hyperthermia therapy (MHT) are included. The results of our recent MHT study on Gd-doped SPION as a possible theranostic agent are highlighted. We have also discussed the challenges and outlook on the future research for theranostics in clinical settings.
Download or read book Cancer Nanotheranostics written by P. Gopinath and published by Springer. This book was released on 2015-03-10 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief provides a clear insight of the recent advances in the field of cancer theranostics with special emphasis upon nano scale carrier molecules (polymeric, protein and lipid based) and imaging agents (organic and inorganic).
Download or read book Cancer Theranostics written by Xiaoyuan Chen and published by Academic Press. This book was released on 2014-03-20 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. - Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy - Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine - Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management
Download or read book Nanomedicine Nanotheranostics and Nanobiotechnology written by Rishi Paliwal and published by CRC Press. This book was released on 2024-09-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanosized particles explored for therapeutics and diagnosis-related research areas need the latest updated information for budding researchers as well as academicians. Nanomedicine, nanotheranostics, and nanobiotechnology have been contemporary technological tools for diverse biomedical, pharmaceutical, and diagnostic solutions. The present book is divided into two sections. The first section is dedicated to exclusive book chapters related to nanomedicine such as its history, regulatory aspects, scale-up, and regulatory toxicology. Additionally, this section includes chapters focusing on the application domain of nanomedicine for targeted cancer therapy, rheumatoid arthritis management, psoriasis treatment, ocular delivery, topical applications, oral bioavailability enhancement, and pulmonary delivery. The second section is composed of chapters in the area of nanotheranostics and applications of nanobiotechnology. In brief, the latest topics such as gold nanoparticles in diagnostics and therapy, nanoparticles for siRNA delivery, carbon nanotubes for gene delivery, nanoparticles for vaccine delivery, nanobiotechnology in cell-based nanomedicines, nanotechnology in regenerative medicine, and nanocarriers in delivery of proteins and peptides are complied. KEY FEATURES A total of 26 emerging topics are covered in the book on cutting-edge research areas at the multi-disciplinary level. The chapters focus on fundamentals and applications, making the book attractive for beginners as well as experts. The chapters are written by well-known experts of the field in a simple scientific style with figures, schemes, and illustrations.
Download or read book Carbon Dots As Theranostic Agents written by Madhuri Sharon and published by Wiley-Scrivener. This book was released on 2018-09-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed for researchers and students interested in carbon dots applications in health care, especially as a theranostic agent. Carbon Dots as Theranostic Agents focuses on the fundamental understanding along with the applications of this unique fluorescent nano-biomachine. The book begins with the explanation that carbon dots fall between the usual daily macro or bulk physics and the quantum mechanics and covers their unique properties like quantum mechanics and quantum confinement. It then encompasses the domain of various physical, chemical and biological methods that efficiently synthesizes the carbon dots and their desired properties. The basic characterization techniques used for carbon dots is also covered in this book. Conjugation of carbon dots with different moieties is another aspect that enhances its applications, hence this is highlighted too. The book also details how to maneuver the carbon dots for their use in targeted drug delivery with emphasis on cancer and neurodegenerative disease as well as cellular imaging and diagnostics. One of the unique features of this book is that it reports on the use of carbon dots to act as a nano-fertilizer, as a drug/antibiotic delivery vehicle to diseased plants through foliar application.
Download or read book Nanostructured Materials written by Mohindar Seehra and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: There continues to be a worldwide interest in the size-dependent properties of nanostructured materials and their applications in many diverse fields such as catalysis, sensors, energy conversion processes, and biomedicine to name a few. The eleven chapters of this book written by different researchers include four chapters on the different methods of fabrication of specific materials followed by characterization of their properties, and the remaining seven chapters focusing on the fabrications and applications including three chapters on biomedical applications, two chapters on sensors, one chapter on solar cells, and one chapter on the use of nanoparticles in herbicides. These chapters provide up-to-date reviews useful for current and future researchers in these specific areas.
Download or read book Nanotechnology Theranostics in Livestock Diseases and Management written by Minakshi Prasad and published by Springer Nature. This book was released on with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt:
