Download or read book Schistosomes Liver Flukes and Helicobacter Pylori written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1994 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates the carcinogenic risk to humans posed by infection with three schistosoma trematodes, three liver flukes and the bacterium Helicobacter pylori. These biological agents were selected for evaluation on the basis of evidence suggesting a causal association between infection and the development of human cancers. The first monograph assesses data on Schistosoma haematobium S. mansoniand S. japonicum, the three species which account for the vast majority of schistosomal disease in humans. The most extensive sections evaluate the results of studies of cancer in humans and experimental animals, concentrating on the strength of evidence linking infection with S. haematobium to squamous-cell carcinoma of the urinary bladder, and infection with S. mansoni or S. japonicum to an increased risk for cancers of the gastrointestinal tract. The monograph concludes that infection with S. haematobium is carcinogenic to humans and that infection with S. japonicum is possibly carcinogenic to humans; infection with S. mansoni could not be classified. The second monograph on liver flukes evaluates data on Opisthorchis viverriniO. felineus and Clonorchis sinensis. These foodborne trematodes establish a chronic infection of the bile ducts and more rarely the pancreatic duct and gall-bladder of humans and other mammals. Most carcinogenicity data centre on the possibility that these trematodes are involved in the development of cholangiocarcinoma or liver cancer. The monograph concludes that infection with O. viverrini is carcinogenic to humans and that infection with C. sinensis is probably carcinogenic to humans; infection with O. felineus could not be classified. The final monograph evaluates data on Helicobacter pylori. More than half of the world's population may be infected with this bacterium, which is responsible for most cases of chronic gastritis and duodenal ulcer. Citing several studies linking infection to gastric cancer in humans, the monograph concludes that infection with H. pylori is carcinogenic to humans.

Download or read book Principles and Practice of Gastrointestinal Oncology written by David Kelsen and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care. The initial section, Principles of Gastrointestinal Oncology, includes an expanded radiation oncology chapter, an extensively revised cancer genetics chapter, and a completely rewritten medical oncology chapter emphasizing new agents. Subsequent sections focus on esophageal, gastric, pancreatic, hepatocellular, biliary tree, and colorectal cancer. Coverage of each anatomic site includes epidemiology, screening, and prevention; molecular biology and genetics; pathology; anatomy and staging; and clinical management. The final section on uncommon cancers includes new chapters on neuroendocrine tumors and small bowel cancers. A companion Website provides instant access to the complete, fully searchable text.

Download or read book Helicobacter Pylori in the 21st Century written by Philip Sutton and published by CABI. This book was released on 2010 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Download or read book Helicobacter pylori written by Nayoung Kim and published by Springer Nature. This book was released on with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Helicobacter pylori and Gastric Cancer written by Steffen Backert and published by Springer Nature. This book was released on 2024-01-17 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed. Helicobacter pylori is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world’s population. H. pylori and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by this bacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer-related death worldwide. H. pylori is the first bacterium that has been classified as a type-I carcinogen by the International Agency for Research on Cancer (IARC). Recent research progress identified crucial bacterial, host and environmental factors which control H. pylori-induced gastric malignancy. New studies also suggest that specific human germline mutations and other genetic aberrations have an important impact on H. pylori-induced pathology. In this volume, all these recently discovered mechanisms are reviewed in the light of gastric cancer development, and H. pylori epidemiology, virulence factors, immune evasion, pathophysiology, cancer signalling and novel therapeutic protocols are presented. This volume is aimed at researchers in the fields of immunology, genetics, microbiology and medicine who are interested in the detailed mechanisms of the pathogenicity of this carcinogenic stomach bacterium.

Download or read book Asiatic Liver Fluke From Basic Science to Public Health Part B written by and published by Academic Press. This book was released on 2018-11-12 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asiatic Liver Fluke - From Basic Science to Public Health, Volume 102, is a well-known and respected outlet for detailed and comprehensive reviews written by experts covering all aspects of parasitology. This latest release covers topics of interest, including Plasmodium genetics: An approach to learn and end human, Leishmania tropica: what we know from experimental models, Extracellular vesicles in host-parasite interaction, Cathepsins and vaccines for fascioliasis, and Evolution in fungi and drug resistance. Presents a well-known and respected outlet for detailed and comprehensive reviews written by experts covering all aspects of parasitology Includes sections that cover taxonomy, ecology and population genetics

Download or read book Vascular Responses to Pathogens written by Felicity N.E. Gavins and published by Academic Press. This book was released on 2015-10-31 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Download or read book Textbook of Gastroenterology written by Tadataka Yamada and published by John Wiley & Sons. This book was released on 2011-10-13 with total page 7321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past twenty years, thousands of physicians have come to depend on Yamada’s Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them was—and still is—beyond compare. This new edition provides the latest information on current and projected uses of major technologies in the field and a new section on diseases of the liver. Plus, it comes with a fully searchable CD ROM of the entire content.

Download or read book From Inflammation to Cancer written by Chi Hin Cho and published by World Scientific. This book was released on 2012 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs. The authors in this book comprehensively discuss the different biomarkers for early diagnosis, and current therapeutic treatments for these diseases. All of these would allow us to better understand the pathogenesis of both diseases. As such, this book provides comprehensive information concerning the interrelationship between inflammation and cancer in a cohesive manner, and the information derived would benefit not only basic scientists but also clinicians who are working in these fields.

Download or read book Emerging foodborne pathogens written by Yasmine Motarjemi and published by CRC Press. This book was released on 2006-06-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments such as the increasing globalization of the food industry, constant innovations in technologies and products, and changes in the susceptibility of populations to disease have all highlighted the problem of emerging pathogens, either newly discovered through more sensitive analytical methods, linked for the first time to disease in humans, or newly associated with a particular food. Designed for microbiologists and quality assurance professionals and for government and academic food safety scientists, this timely reference discusses ways of identifying emerging pathogens and includes chapters on individual pathogens, their epidemiology, methods of detection, and means of control.

Download or read book Gastritis and Gastric Cancer written by Paola Tonino and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gastric Cancer An Issue of Gastroenterology Clinics written by Steven Moss and published by Elsevier Health Sciences. This book was released on 2013-06-28 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer is the second most common cause of cancer mortality worldwide. Although the incidence of gastric cancer has declined over the past century in the United States, it remains one of the most common gastrointestinal neoplasms, particularly in immigrants and the socio-economically deprived. Recent years have seen major advances in our understanding of the pathogenesis of gastric cancer (especially regarding the importance of Helicobacter pylori and its associated inflammatory response) and the emergence of adjuvant oncologic therapies of proven benefit for advanced cases, in addition to surgery. As for gastric adenocarcinoma, elucidation of the underlying biology and molecular pathogenesis has led to much progress in the management of two other malignant gastric neoplasms, gastrointestinal stromal tumors and marginal zone B-cell (“MALT ) lymphomas. This monograph highlights these developments, presenting an updated overview of gastric cancer that will be of interest to all practicing gastroenterologists.

Download or read book Gastric Cancer written by Akiko Shiotani and published by Springer. This book was released on 2018-11-02 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential insights into the various pathogeneses, diagnoses and therapies for patients with gastric cancer. Special attention is given to trending topics: endoscopic diagnosis, cancer screening and eradication of H. pylori as prevention of the disease. A dedicated section focuses on risk classification and cancer screening/diagnosis, and is intended for practical use in clinical doctors’ day-to-day management of patients. Since cancer screening and prevention is currently only practiced in Japan, this book is intended to disseminate new findings and serve as a point of departure for further research. Abundant color illustrations of the enhanced endoscopic imaging are also included, making it a valuable resource for GI medical doctors, medical students and those seeking detailed information on H. pylori.​

Download or read book Esophageal Disease and the Role of the Microbiome written by David A. Johnson and published by Elsevier. This book was released on 2022-11-29 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Esophageal Diseases and the Role of the Microbiome provides evidence on biomic influence in esophageal diseases. The book builds on the translational information on H pylori for ulcer disease as well as the explosive focus on biomic influence in virtually all areas of esophageal diseases. This important reference will help translational researchers by providing scientific understanding and hypothesis generation that is needed for furthering this field of study. It will also provide clinicians with disease management options for esophageal diseases (for GERD and PPI options/side effects) and present cutting-edge science to promote provider/patient understanding and options. - Delivers a translational understanding of new paradigms for esophageal disease - Explains the effects of microbiome balance in the esophagus - Suggests potential treatment options of esophageal dysbiosis

Download or read book Dental Management of the Medically Compromised Patient Pageburst on VitalSource written by James W. Little and published by Elsevier Health Sciences. This book was released on 2007-07-24 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ensure your patients' health and safety! Practical guidance helps you determine the severity and stability of common medical disorders in the dental office, so you'll always know how to proceed to provide the best possible care and avoid complications. Concise, clinically focused coverage details the basic disease process for each condition, along with the incidence and prevalence, pathophysiology, signs and symptoms, laboratory findings, currently accepted medical therapies, and recommendations for specific dental management. Reference lists provide places where the reader can go to obtain more detailed information on the topics discussed in the chapter. Dental Management Summary Table synthesizes important factors for consideration in the dental management of medically compromised patients. Center for Disease Control and Prevention Guidelines for Infection Control in Dental Health Care Settings appendix provides certified standards for infection control. Therapeutic Management of Common Oral Lesions appendix provides quick reference for lesions commonly encountered in dental practice. Drug Interactions of Significance to Dentistry appendix alerts practitioners to potential drug interactions. For the first time, the table of contents will be divided into parts by the category of medical condition, making it faster and easier for the dental professional to search by condition. Bacterial Endocarditis Prophylaxis, Chapter 2, incorporates the latest American Heart Association guidelines to help prevent endocarditis. Smoking and Tobacco Use Cessation, Chapter 8, discusses the systemic and oral effects of smoking and includes suggestions for encouraging smoker cessation. Tuberculosis, Chapter 9, clearly defines related oral complications and adverse drug effects of the disease and identifies methods for management in dental patients. Sleep-Related Breathing Disorders, Chapter 10, details obstructive sleep apnea and treatment options including oral appliances and surgical procedures. Rheumatologic and Connective Tissue Disorders, Chapter 21, discusses treatment options for patients with rheumatoid arthritis, Osteoarthritis, Systemic Lupus Erythematosus, Lyme Disease, and Sjögren's Syndrome. Chapters 23 and 24 highlight the oral complications of both red and white blood cell disorders. Behavioral and Psychiatric Disorders, Chapters 28 and 29, provide guidelines for managing conditions like depression, eating disorders, anxiety, and schizophrenia, and indicate proper drugs for treatment. Alternative Drugs Appendix provides treatment options from the growing areas of alternative and complementary medicine.

Download or read book Preventive Nutrition written by Adrianne Bendich and published by Springer Science & Business Media. This book was released on 2010-04-19 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this major revision and expansion of a highly respected reference work, the authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. This new edition combines fully updated versions of the best chapters of the first two editions with updated critical chapters from the much-praised Primary and Secondary Preventive Nutrition, and adds 16 new chapters. Here, practicing health professionals will find all new reviews of lycopene, tomatoes and prostate cancer, soy and cancer prevention; the effects of dietary supplement use on prescription drugs, osteoarthritis, osteoporosis, and cardiovascular disease; balanced, data-driven reviews of the effects of antioxidant supplements on health outcomes, and more. By synthesizing the latest data and integrating it into the broad body of existing information, this book provides in-depth guidance on nutrition and the prevention of cancer, cardiovascular disease, bone diseases, obesity, and diabetes, and on achieving optimal pregnancies and birth outcomes.