Download or read book Quantitive Analysis Of Biospec written by Per Lundahl and published by Routledge. This book was released on 2021-09-01 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 2004, this book collects several up-to-date methods for quantitative analysis of biospecific interactions, a field that has a long history that perhaps can be said to have begun with the classical paper of G. Scatchard in 1949 (The attractions of proteins for small molecules and ions, but which has advanced impressively during the last few years. A precise spatial arrangement of just a few hydrogen bonds can confer a remarkably specific reversible association between two molecules. A web of weak interactions governs biospecific recognition in general. The binding equilibria in living cells tune and coordinate a multitude of functions. The thermodynamic properties of such interactions are often studied by binding experiments in simplified and essentially ideal systems. However, similar types of studies may elucidate the biologically relevant dynamic steady-state conditions in living cells and organisms, allowing for the very wide range of interactant concentrations and the interplay between the many reactions and interactions. The development in biosciences will continue with in-depth studies of macromolecules and membranes. More detailed knowledge will allow analyses of delicate balances between substances and events in the complex systems involved in life processes. Methods to study biospecific affinities are thus highly important tools for understanding mechanisms and effects of molecular binding events in vivo and in vitro, e.g., in biochemical, biomedical and pharmaceutical research, and for biotechnological research and production.
Download or read book Medical Complications of Type 2 Diabetes written by Colleen Croniger and published by BoD – Books on Demand. This book was released on 2011-09-12 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes.
Download or read book Failure Analysis of Microbiologically Influenced Corrosion written by Richard B. Eckert and published by CRC Press. This book was released on 2021-11-07 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Failure Analysis of Microbiologically Influenced Corrosion serves as a complete guide to corrosion failure analysis with an emphasis on the diagnosis of microbiologically influenced corrosion (MIC). By applying the principles of chemistry, microbiology, and metallurgy, readers will be able to reliably determine the mechanistic cause of corrosion damage and failures and select the appropriate methods for mitigating future corrosion incidents. FEATURES Provides background information on the forensic process, types of data or evidence needed to perform the analysis, industrial case studies, details on the MIC failure analysis process, and protocols for field and lab use Presents up-to-date advances in molecular technologies and their application to corrosion failure investigations Offers specific guidelines for conducting MIC failure analyses and case studies to illustrate their application Examines state-of-the-art information on MIC analytical tools and methods With authors with expertise in microbiology, corrosion, materials, and failure investigation, this book provides tools for engineers, scientists, and technologists to successfully combat MIC issues.
Download or read book Infant Gut Microbiota Colonization and Food Impact written by Christophe Lacroix and published by Frontiers Media SA. This book was released on 2019-05-23 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Computational Intelligence A Compendium written by John Fulcher and published by Springer. This book was released on 2008-05-28 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Intelligence: A Compendium presents a well structured overview about this rapidly growing field with contributions from leading experts in Computational Intelligence. The main focus of the compendium is on applied methods, tried-and-proven as being effective to realworld problems, which is especially useful for practitioners, researchers, students and also newcomers to the field. This state-of- handbook-style book has contributions by leading experts.
Download or read book The Unfolded Protein Response and Cellular Stress written by P. Michael Conn and published by Academic Press. This book was released on 2011 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights
Download or read book XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 written by Laura M. Roa Romero and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 1978 pages. Available in PDF, EPUB and Kindle. Book excerpt: The general theme of MEDICON 2013 is "Research and Development of Technology for Sustainable Healthcare". This decade is being characterized by the appearance and use of emergent technologies under development. This situation has produced a tremendous impact on Medicine and Biology from which it is expected an unparalleled evolution in these disciplines towards novel concept and practices. The consequence will be a significant improvement in health care and well-fare, i.e. the shift from a reactive medicine to a preventive medicine. This shift implies that the citizen will play an important role in the healthcare delivery process, what requires a comprehensive and personalized assistance. In this context, society will meet emerging media, incorporated to all objects, capable of providing a seamless, adaptive, anticipatory, unobtrusive and pervasive assistance. The challenge will be to remove current barriers related to the lack of knowledge required to produce new opportunities for all the society, while new paradigms are created for this inclusive society to be socially and economically sustainable, and respectful with the environment. In this way, these proceedings focus on the convergence of biomedical engineering topics ranging from formalized theory through experimental science and technological development to practical clinical applications.
Download or read book OPLL written by Atsushi Okawa and published by Springer Nature. This book was released on 2020-05-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication brings together information on all aspects of OPLL - epidemiology, etiology, diagnosis, and treatment. It contains contributions by Japanese researchers and surgeons, including members of the Ministry of Health and Welfare Investigation Committee, and by American surgeons with expertise in the field. Until now, little has been published on the subject in English. This collection of reports is amply augmented with illustrations.
Download or read book Effects of perinatal opioid exposure volume II written by Henrietta S. Bada and published by Frontiers Media SA. This book was released on 2024-04-17 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition for Brain Health and Cognitive Performance written by Talitha Best and published by CRC Press. This book was released on 2015-06-12 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public awareness of the role diet plays in brain function has been steadily increasing. This has led to significant development of new products, dietary supplements, functional foods, nutraceuticals and public health recommendations for maintaining brain function. Nutrition for Brain Health and Cognitive Performance presents a detailed and innovati
Download or read book Genetic Engineering Biotechnology News written by and published by . This book was released on 2009 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bifidobacteria and Their Role in the Human Gut Microbiota 2nd Edition written by Francesca Turroni and published by Frontiers Media SA. This book was released on 2020-02-14 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human intestine is home of an almost inconceivable large number of microorganisms. The human gut microbiota can therefore be pictured as an organ placed within a host organism. The human gut microbiome, which in total may contain >100 times the number of genes present in our genome, endows us with functional features that we did not have to evolve ourselves. It is recognized that intestinal microbiota plays an important role in human health and disease. In fact, gut bacteria other than metabolize dietary components, may play complex roles such as modulation of the immune system and in reduction of gut infections. Variations in the presence and/or abundance of certain components of the intestinal microbiota have repeatedly been observed in patients that suffer from atopic diseases, inflammatory bowel disease, Crohn disease, ulcerative colitis, infectious colitis, colon cancer and diabetes. In this context, bifidobacteria represent one of the most common bacterial members of the human gut microbiota. Bifidobacteria are anaerobic, Gram-positive, irregular or branched rod-shaped bacteria that are commonly found in the gastro-intestinal tracts (GIT) of humans, especially during the first stages of life and most animal and insects. Bifidobacterial fluctuations seem directly associated with health effects and for these reasons they are being exploited as health-promoting or probiotic bacteria. However, despite the extensive commercial exploitation of bifidobacteria as probiotic bacteria, little is known about their impact or dependency on other members of the human gut microbiota or on their host. Genome analyses have highlighted the existence of gene repertoires encoding products that are responsible for the adaptation of bifidobacteria to the human intestine and intense research efforts at international level are ongoing to understand the molecular details of these interactions. Specifically, the molecular interactions that are presumed to exist between bifidobacteria and the human host, as well as interactions between different residents of intestinal microbiota are the main topic of bifidobacterial research communities.
Download or read book Role of Microbiome in Disease Diagnostics and Therapeutics written by Nar Singh Chauhan and published by Frontiers Media SA. This book was released on 2022-10-07 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book FDA Enforcement Report written by and published by . This book was released on 1983 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Integration of Omics Approaches and Systems Biology for Clinical Applications written by Antonia Vlahou and published by John Wiley & Sons. This book was released on 2018-01-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.
Download or read book Microbiome Interplay and Control written by Christine Moissl-Eichinger and published by Frontiers Media SA. This book was released on 2018-07-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorganisms. This Research Topic focuses on studies (including e.g. original research, perspectives, mini reviews, and opinion papers) that investigate and discuss: 1) The role of the microbiome for the host/environmental system 2) The exchange and change of microbes and microbial communities (interplay) 3) The influence of external factors toward the stability of a microbiome 4) Methods, possibilities and approaches to change and control a system’s microbiome (e.g. in human or plant disease) 5) Experimental systems and approaches in microbiome research. The articles span the areas: human health and disease, animal and plant microbiomes, microbial interplay and control, methodology and the built environment microbiome.
