Download or read book Prostaglandins in the Perinatal Period written by Michael A. Heymann and published by Saunders. This book was released on 1980-01-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human and Ovine Studies on the Control of Prostaglandins in the Perinatal Period written by Shaun Patrick Brennecke and published by . This book was released on 1984 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human and Ovine Studies on the Control of Prostaglandins in the Perinatal Period written by Shaun Patrick Brennecke and published by . This book was released on 1984 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and Perinatal Medicine written by Flavio Coceani and published by . This book was released on 1978 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and Perinatal Medicine written by Canada) Hospital for Sick Children (Toronto and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and Pregnancy written by Lois Adrienne Salamonsen and published by CSIRO Publishing. This book was released on 1990-01-01 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collection of papers from a symposium held in 1989 organised by the Centre for Reproductive Biology and the Department of Obstetrics and Gynaecology, Monash University. Of interest to both scientists and clinicians, it summarises current knowledge of eicosanoids in reproductive biology, and prostaglandins and their analogues in clinical gynaecological and obstetrical practice. Includes references. Reprinted from the journal TReproduction, Fertility and Development' (1990).
Download or read book Prostaglandins and the Uterus written by James O. Drife and published by Springer. This book was released on 1992 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of prostaglandins into clinical practice has been one of the most important advances in obstetrics and gynaecology in recent years. During the last decade obstetricians have become familiar with these drugs for inducing labour and for terminating second-trimester pregnancy. Within the last year their use has been extended, in association with antiprogestin, to first-trimester termi nation. Although the effectiveness of prostaglandins in these pharma cological roles is clear, their full potential has still to be explored, and much remains to be learned about their physiology. Prostaglandins playa central role in the initiation of labour. Further clarification of this role could lead to improvements in preventing or treating preterm labour, which still remains the most important cause of perinatal mortality in this country. Prostaglandins are also inti mately involved in the mechanism of menstruation. More detailed understanding of this role should lead to more effective treatments for menorrhagia and dysmenorrhoea. These substances also playa part in the mechanism of implantation, and further research in this area may lead to more effective therapy for infertility.
Download or read book Etiology and Morphogenesis of Congenital Heart Disease written by Toshio Nakanishi and published by Springer. This book was released on 2018-06-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.
Download or read book Prostaglandin Transport and Catabolism in the Choroid Plexus During Perinatal and Postnatal Development in Sheep written by Nancy Krunic and published by . This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In sheep, the marked decrease in prostaglandin (PG)E2 levels in ventricular cerebrospinal fluid (CSF) after birth is believed to promote continuous breathing. Factors responsible flor this decrease are unknown. In adults, prostaglandins are cleared from CSF to plasma by carrier-mediated, probenecid-sensitive transport across the choroid plexus. Circulating prostaglandins are cleared from plasma. by a similar carrier in lungs and kidneys. Carrier-mediated transport is rate-limiting for catabolism via 15-hydroxyprostaglandin dehydrogenase (15-PGDH) at these sites. It is not known whether carrier-mediated transport and/or 15-PGDH-mediated catabolism operate in the choroid plexus during perinatal development, or if an increase in their activities contributes to the postnatal decrease in CSF PGE2. To address these questions, we examined in vitro 3H-PGE2 and 3H-PGF2Ã uptake and catabolism by the sheep choroid plexus using liquid scintillation spectrometry and thin-layer radiochromatography. 15-PGDH was localized by immunofluorescence and immunogold histochemistry. In the term fetus, PGE 2 and PGF2Ã were accumulated against a concentration-gradient in a saturable, probenecid-sensitive, time- and temperature-dependent manner. Uptake was similar in fetuses (preterm and term) and lambs (~5 and 15 d) and tended to be higher in adults. In the fetus, both prostaglandins were extensively catabolized by 15-PGDH. PGE2 catabolism did not change during the perinatal period, while PGF2, catabolism decreased soon after birth. Catabolism was probenecid-insensitive and, thus, functioned independently of uptake. In adults, catabolism was marginal and, accordingly, 15-PGDH was undetectable. In fetuses, 15-PGDH was localized near the CSF-facing membrane of epithelial cells. In lambs, 15-PGDH was localized, instead, in stromal fibroblasts. PGE2 catabolism did not change in association with the postnatal relocalization of 15-PGDH, whereas PGF2Ã catabolism decreased. This study confirms that, in the perinatal sheep as in the adult, prostaglandins can be cleared from CSF via carrier-mediated transport across the choroid plexus. Contrary to the adult, in the fetus, prostaglandins are completely catabolized in the choroid plexus. The postnatal fall in CSF PGE 2 cannot be attributed to increased clearance via either transport or catabolism in the choroid plexus. However, the concomitant activity of the prostaglandin carrier and 15-PGDH may help to maintain PGE2 low in neonates and, by extension, to sustain continuous breathing.
Download or read book Prostaglandins and their Inhibitors in Clinical Obstetrics and Gynaecology written by M. Bygdeman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is clear today that several prostaglandins play an important role in the regulation of many of the physiological events of the reproductive organs in the human. Both naturally occurring prostaglandins and their analogues are used routinely in many countries to ripen the cervix and induce labour at term as well as to dilate the cervix and to terminate pregnancy. Prostaglandin biosynthesis inhibitors are widely used in the treatment of primary dysmenorrhoea. The editors have aimed at an accurate, thorough, yet easily under standable review of the status in 1986 of medical knowledge regarding both the physiological importance and the clinical use of prostaglan dins and their inhibitors in obstetrics and gynaecology. I believe this book will be of value for all clinicians concerned with reproductive health. The list of authors guarantees an authoritative and up-to-date review of this active field. SUNE BERGSTROM Karolinska Institutet, Stockholm, Sweden Table Examples of clinical use of natural prostaglandins and some prostaglandin analogues Indications Prostaglandin Route of administration Manufacturer Dilatation of the cervix prior 15-methyl-PGF • Intramuscular Upjohn, USA 2 to vacuum aspiration 16-phenoxy-PGE methyl sulphonylamide Intramuscular Schering AG, West Germany 2 16,16-dimethyl-PGE methyl ester 1 Vaginal ONO, Japan; May & Baker, UK Second trimester abortion Intra -amniotic Upjohn, USA; ONO, Japan PGF 20 Upjohn, USA PGE Vaginal 2 Upjohn, USA 15-methyl-PGF 2.
Download or read book WHO Recommendations written by World Health Organization and published by . This book was released on 2018 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary goal of this guideline is to provide a foundation for the implementation of interventions shown to have been effective in reducing the burden of PPH (postpartum haemorrhage). Health professionals responsible for developing national and local health policies constitute the main target audience of this document. Obstetricians, midwives, general medical practitioners, health care managers and public health policy-makers, particularly in under-resourced settings are also targeted. This document establishes general principles of PPH care and it is intended to inform the development of clinical protocols and health policies related to PPH.
Download or read book Best Practice in Labour and Delivery written by Sir Sabaratnam Arulkumaran and published by Cambridge University Press. This book was released on 2016-11-24 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of revised recommendations for intrapartum care, this updated edition reviews best practice in all aspects of labour and delivery.
Download or read book Prostaglandins Leukotrienes and Lipoxins written by J. Bailey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins and Related Substances written by and published by Elsevier. This book was released on 1983-01-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostaglandins and Related Substances
Download or read book The Fetus and Birth written by Julie Knight and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.
Download or read book Translational Biology in Medicine written by M. Montano and published by Elsevier. This book was released on 2014-12-08 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine. Describes cellular and animal model systems used in translational research Discusses the use of blood, genetic and genomic biomarkers for disease Presents translational studies in aging, tissue repair and infectious disease biomedicine
