Download or read book Practical Biostatistics in Translational Healthcare written by Allen M. Khakshooy and published by Springer. This book was released on 2018-06-23 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an ever-increasing emphasis on evidence-based medicine that is distinguished by systematic crafting of the patient-centered research question, detailed literature searches, and careful appraisal of the resulting evidence. The consensus that ultimately emerges must then be applied in specific clinical settings, and it is to this process that translational effectiveness analysis refers. This portable and easy-to-use handbook is intended as a practical teaching guide on translational effectiveness for students and clinicians. Specifically, it will serve as a primer on patient-centered outcomes research methodology in the health sciences and explain how to acquire and understand the fundamental data that determine which reports are valued as the “best available” evidence. It presents an accessible and readily intelligible set of principles which doctors, dentists, nurses, and insurance carriers will be able to use in the process of health care-related decision-making. ​

Download or read book Dental Sleep Medicine written by G. Gary Demerjian and published by Springer Nature. This book was released on 2022-09-29 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to enable dentists to understand various aspects of dental sleep medicine, and to recognize the signs and symptoms of sleep disorders in their patients. It discusses potential negative impact of a sleep disorder on oral and systemic health, and shows how to collaborate with others in order to implement appropriate patient management. The first part of the book concentrated on the scientific background of sleep medicine in connection to dentistry covering the physiology of sleep, classifications of sleep disorders, their diagnosis as well as medical and dental comorbidities. The second part of the book is dedicated to clinical applications like CPAP therapy, oral appliance therapy, surgical procedures and adjunct therapies. Last, the future of dental sleep medicine is discussed. Each chapter is written by specialized researchers and clinicians in the field making the book a useful guide for dental clinicians all around the world.

Download or read book All About Bioinformatics written by Yasha Hasija and published by Elsevier. This book was released on 2023-04-05 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the _x001F_field of bioinformatics, as well as some future directions. Each chapter is didactically organized and includes introduction, applications, tools, and future directions to cover the topics thoroughly. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high-throughput technologies, drug informatics, system and network biology, and machine learning. It is a valuable resource for researchers and graduate students who are interested to learn more about bioinformatics to apply in their research work. - Presents a holistic learning experience, beginning with an introduction to bioinformatics to recent advancements in the field - Discusses bioinformatics as a practice rather than in theory focusing on more application-oriented topics as high-throughput technologies, system and network biology, and workflow management systems - Encompasses chapters on statistics and machine learning to assist readers in deciphering trends and patterns in biological data

Download or read book Global Virology III Virology in the 21st Century written by Paul Shapshak and published by Springer Nature. This book was released on 2019-11-22 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Virology, Volume III: Virology in the 21st Century examines work that has been undertaken, or is planned, in several fields of virology, in an effort to promote current and future work, research, and health. Fields and methods addressed include virology, immunology, space research, astrovirology/astrobiology, plasmids, swarm intelligence, bioinformatics, data-mining, machine learning, neural networks, critical equations, and advances in biohazard biocontainment. Novel and forward-looking methods, techniques, and approaches in research and development are presented by experts in the field.

Download or read book Practical Considerations for Adaptive Trial Design and Implementation written by Weili He and published by Springer. This book was released on 2014-10-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, in particular, statisticians, clinicians, pharmacometricians, clinical operation specialists, drug supply managers, and infrastructure providers. In spite of the increased efficiency of adaptive trials in saving costs and time, ultimately getting drugs to patients sooner, their adoption in clinical development is still relatively low. One of the chief reasons is the higher complexity of adaptive design trials as compared to traditional trials. Barriers to the use of clinical trials with adaptive features include the concerns about the integrity of study design and conduct, the risk of regulatory non-acceptance, the need for an advanced infrastructure for complex randomization and clinical supply scenarios, change management for process and behavior modifications, extensive resource requirements for the planning and design of adaptive trials and the potential to relegate key decision makings to outside entities. There have been limited publications that address these practical considerations and recommend best practices and solutions. This book fills this publication gap, providing guidance on practical considerations for adaptive trial design and implementation. The book comprises three parts: Part I focuses on practical considerations from a design perspective, whereas Part II delineates practical considerations related to the implementation of adaptive trials. Putting it all together, Part III presents four illustrative case studies ranging from description and discussion of specific adaptive trial design considerations to the logistic and regulatory issues faced in trial implementation. Bringing together the expertise of leading key opinion leaders from pharmaceutical industry, academia, and regulatory agencies, this book provides a balanced and comprehensive coverage of practical considerations for adaptive trial design and implementation.

Download or read book Introductory Biostatistics written by Chap T. Le and published by John Wiley & Sons. This book was released on 2016-04-22 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintaining the same accessible and hands-on presentation, Introductory Biostatistics, Second Edition continues to provide an organized introduction to basic statistical concepts commonly applied in research across the health sciences. With plenty of real-world examples, the new edition provides a practical, modern approach to the statistical topics found in the biomedical and public health fields. Beginning with an overview of descriptive statistics in the health sciences, the book delivers topical coverage of probability models, parameter estimation, and hypothesis testing. Subsequently, the book focuses on more advanced topics with coverage of regression analysis, logistic regression, methods for count data, analysis of survival data, and designs for clinical trials. This extensive update of Introductory Biostatistics, Second Edition includes: • A new chapter on the use of higher order Analysis of Variance (ANOVA) in factorial and block designs • A new chapter on testing and inference methods for repeatedly measured outcomes including continuous, binary, and count outcomes • R incorporated throughout along with SAS®, allowing readers to replicate results from presented examples with either software • Multiple additional exercises, with partial solutions available to aid comprehension of crucial concepts • Notes on Computations sections to provide further guidance on the use of software • A related website that hosts the large data sets presented throughout the book Introductory Biostatistics, Second Edition is an excellent textbook for upper-undergraduate and graduate students in introductory biostatistics courses. The book is also an ideal reference for applied statisticians working in the fields of public health, nursing, dentistry, and medicine.

Download or read book Translational Bioinformatics in Healthcare and Medicine written by and published by Academic Press. This book was released on 2021-05-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. - Covers recent advancements in translational bioinformatics and its healthcare applications - Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management - Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Download or read book Exploration of Artificial Intelligence and Blockchain Technology in Smart and Secure Healthcare written by Arvind K. Sharma, Dalip Kamboj, Savita Wadhawan, Gousia Habib, Samiya Khan, Valentina Emilia Balas and published by Bentham Science Publishers. This book was released on 2024-03-27 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers in-depth reviews of different techniques and novel approaches of using blockchain and artificial intelligence in smart healthcare services. The volume brings 14 reviews and research articles written by academicians, researchers and industry professionals to give readers a current perspective of smart healthcare solutions for medical and public health services. The book starts with examples of how blockchain can be applied in healthcare services such as the care of osteoporosis patients and security. Several chapters review AI models for disease detection including breast cancer, colon cancer and anemia. The authors have included model design and parameters for the benefit of professionals who want to implement specific algorithms. Furthermore, the book also includes chapters on IoT frameworks for smart healthcare systems, giving readers a primer on how to utilize the technology in this sector. Additional use cases for machine learning for gesture learning. COVID-19 management, and sentiment analysis.

Download or read book Research Methodology and Biostatistics E book written by Suresh Sharma and published by Elsevier Health Sciences. This book was released on 2016-12-14 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Research Methodology and Biostatistics—A Comprehensive Guide for Health Care Professionals is a precisely written textbook for undergraduate and postgraduate medical, dental, nursing, physiotherapy, clinical psychology and other allied health care profession students. The book is an excellent attempt towards introducing the students and faculty members to the various research methodologies adopted in the field of health sciences to record health-related data. Salient Features Easy to follow: An applied, user-friendly textbook with self-explanatory simple language and presentation for the students. An example-oriented book: Plenty of examples to equip the students to prepare for exams as well as independently conduct their research activities. Illustrative presentation: Diagrammatic and tabular presentation of content to facilitate quick review and recall of important concepts. Systematic and logical organization: Content organized in systematic and logical manner to facilitate better understanding. Qualitative and quantitative research methods, analysis: Adequate coverage of quantitative as well as qualitative research process, methodology and analysis. Authentic content: Content reviewed, authenticated by a panel of renowned faculty members/experts. Unique content: Several unique topics such as sample size calculation, uses of different parametric and nonparametric statistical tests, methods, qualitative research process, and analysis included, with practical examples from Indian scenario, which are rarely found in other research methodology books. Enormous knowledge in a nutshell: In-depth coverage of all aspects of research methodology and biostatistics in a concise manner. Review questions: About 150 end-of-chapter MCQs, a useful resource for the readers to review their preparation for the university exams and also to prepare for qualifying entrance exams for postgraduate and doctoral courses.

Download or read book Exploring Medical Statistics Biostatistics Clinical Trials and Epidemiology written by Arora, Geeta and published by IGI Global. This book was released on 2024-07-18 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In today's data-driven world, understanding and interpreting statistical information is more critical than ever, especially in medicine, where statistical methods are used to design and analyze clinical trials, study the distribution of disease in populations, and develop new treatments. In the era of evidence-based medicine, Exploring Medical Statistics: Biostatistics, Clinical Trials, and Epidemiology addresses the critical need for a grasp of statistical concepts. This book delves into biostatistics, clinical trials, and epidemiology, offering a robust foundation for understanding and interpreting statistical information in medicine. It explores biostatistics, elucidating fundamental elements such as probability, sampling, and hypothesis testing. The section on clinical trials covers the entire spectrum from trial design to ethical considerations, providing an invaluable resource for researchers navigating the complexities of medical research. Epidemiology, a cornerstone of public health, is examined in the book, offering insights into the distribution and determinants of diseases in populations. The application-focused section further extends the utility of medical statistics, encompassing public health, healthcare policy, and drug development.

Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Download or read book Frontiers of Biostatistical Methods and Applications in Clinical Oncology written by Shigeyuki Matsui and published by Springer. This book was released on 2017-10-03 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art of biostatistical methods and their applications in clinical oncology. Many methodologies established today in biostatistics have been brought about through its applications to the design and analysis of oncology clinical studies. This field of oncology, now in the midst of evolution owing to rapid advances in biotechnologies and cancer genomics, is becoming one of the most promising disease fields in the shift toward personalized medicine. Modern developments of diagnosis and therapeutics of cancer have also been continuously fueled by recent progress in establishing the infrastructure for conducting more complex, large-scale clinical trials and observational studies. The field of cancer clinical studies therefore will continue to provide many new statistical challenges that warrant further progress in the methodology and practice of biostatistics. This book provides a systematic coverage of various stages of cancer clinical studies. Topics from modern cancer clinical trials include phase I clinical trials for combination therapies, exploratory phase II trials with multiple endpoints/treatments, and confirmative biomarker-based phase III trials with interim monitoring and adaptation. It also covers important areas of cancer screening, prognostic analysis, and the analysis of large-scale molecular data in the era of big data.

Download or read book Surfacing best practices for AI software development and integration in healthcare written by Mark Sendak and published by Frontiers Media SA. This book was released on 2023-06-08 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Translational Interventional Radiology written by Adam E.M. Eltorai and published by Elsevier. This book was released on 2023-04-05 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Interventional Radiology, a volume in the Handbook for Designing and Conducting Clinical and Translational Research series, covers the principles of evidence-based medicine and applies these principles to the design of translational investigations in Interventional Radiology. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in Interventional Radiology, and know what is needed for successful collaboration. Further, this reference is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps aspiring investigators navigate challenging considerations in study design and implementation. This book provides valuable discussions of the critical appraisal of published studies in Interventional Radiology, elucidating the evaluation of the quality with respect to measuring outcomes and making effective use of all types of evidence in patient care. In short, this practical guide will be of interest to every medical researcher and interventional radiologist who has ever had a good clinical idea but not the knowledge of how to test it. - Focuses on the principles of evidence-based medicine and applies these principles to the design of translational investigations within interventional radiology - Provides a practical, straightforward approach that helps investigators navigate challenging considerations in study design and implementation - Details discussions of the critical appraisal of published studies in interventional radiology, supporting evaluation with respect to measuring outcomes and making effective use of all types of evidence in patient care

Download or read book Applied Biostatistical Principles and Concepts written by Laurens Holmes, Jr. and published by Routledge. This book was released on 2017-11-22 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past three decades have witnessed modern advances in statistical modeling and evidence discovery in biomedical, clinical, and population-based research. With these advances come the challenges in accurate model stipulation and application of models in scientific evidence discovery Applied Biostatistical Principles and Concepts provides practical knowledge using biological and biochemical specimen/samples in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics in attempt to improve the health of patients and populations. This book is suitable for both clinicians and health or biological sciences students. It presents the reality in statistical modelling of health research data in a concise manner that will address the issue of "big data" type I error tolerance and probability value, effect size and confidence interval for precision, effect measure modification and interaction as well as confounders, thus allowing for more valid inferences and yielding results that are more reliable, valid and accurate.

Download or read book Mixed Methods in Health Sciences Research written by Leslie Curry and published by SAGE Publications. This book was released on 2014-09-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mixed Methods in Health Sciences Research: A Practical Primer, by Leslie Curry and Marcella Nunez-Smith, presents key theories, concepts, and approaches in an accessible way. Packed with illustrations from the health sciences literature, this ready-to-use guidebook shows readers how to design, conduct, review, and use mixed methods research findings. Helpful checklists, figures, tables, templates, and much more give readers examples that will elevate the quality of their research, facilitate communication about their methods, and improve efficiency over the course of their projects. Real-world examples and insights from mixed methods researchers provide unique perspectives on every aspect of mixed methods research. This book successfully pulls together foundational mixed methods principles, synthesizes the knowledge base in the field, and translates it for a health science researcher audience. “The content is highly applicable to real life research teams in the areas of clinical research, health services research, and implementation science, providing sound content and practical advice. The authors have synthesized and pull key concepts from a variety of sources to provide a concise resource.” —Linda M. Herrick, South Dakota State University “Everything from the references, to the topics, checklists, conceptual graphic representations, and organizers, interviews, and resources, all contribute to the content and aid with understanding and/or application. … It addresses specific MM research as it pertains to health sciences in a way that other texts just do not even attempt.” —Denise L. Winsor, University of Memphis “[This text is] a very pragmatic approach to mixed methods research; excellent resources, tables, and figures [are] provided, along with cases and examples of value to researchers and grant reviewers. Its relevance to practice, education, and research, as well as to potential policy implications, is a strong focus that would make this a valued textbook for any researcher!” ? —Karen Devereaux Melillo, University of Massachusetts Lowell “The text is cutting edge. It leads the way with its focus on team dynamics. [The authors] succeed in making the book relevant and practical. They also articulate a number of key insights in the area of mixed methods that rarely get addressed, such as teams and conflict. Great read with a lot of good, practical information for mixed methods researchers at all levels. The practical approach of this text makes it an innovative and valuable resource.” —John G. Schumacher, University of Maryland

Download or read book Designing Clinical Research written by Stephen B. Hulley and published by Lippincott Williams & Wilkins. This book was released on 2011-11-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.