Download or read book Platelet Adhesion and Aggregation in Thrombosis Countermeasures written by Eberhard F. Mammen and published by . This book was released on 1970 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Adhesion and Aggregation in Thrombosis written by E. F. Mammen and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Adhesion and Aggregation in Thrombosis written by E. F. Mammen and published by . This book was released on 1970 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Adhesion and Aggregation in Thrombosis Countermeasures written by E.F. Mammen and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Wayne State University School of Medicine Presents The Eighteenth Annual Symposium on Blood written by and published by . This book was released on 1970 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Vessel Wall Interactions in Hemostasis and Thrombosis written by Rolando E. Rumbaut and published by Biota Publishing. This book was released on 2010-02-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.
Download or read book Established and Novel Roles of Platelets in Health and Disease written by Marie Lordkipanidzé and published by Frontiers Media SA. This book was released on 2022-03-02 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Adhesion and aggregation in thrombosis written by Eberhard F. Mammen and published by . This book was released on 1970 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Function and Thrombosis written by P. Mannucci and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fondazione Lorenzini has been sponsoring Postgraduate Courses for physicians and specialists, in Italy, since 1970. Its aim, as an institution, has been that of promoting post graduate medical education. In these years, recent advances in a wide range of medical fields have been discussed by distinguished experts from many countries throughout the world. Courses dealing with methodo logies and technical problems have been designed to include practical demonstrations of the various methods and techniques in the relevant fields. The Postgraduate Course on "Platelets and Thrombosis: Methods of Study" was held in Milan, at the Fondazione Lorenzini, from February 24th to 26th, 1972. This volume contains the edited and somewhat extended papers presented at the Course, which was sponsored and organized by the Italian Society for the Study of Atherosclerosis. The special contribution of the present volume is that of gathering a large amount of up-to-date information on the formidable problem of the methods used for testing platelet function in thrombosis.
Download or read book Manual of Blood Platelets Morphology Physiology and Pharmacology written by Gundu HR Rao and published by Jaypee Brothers Medical Publishers. This book was released on 2018-11-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies. Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to blood platelets for haematologists Extensive coverage of antiplatelet drugs and resistance Recognised author from University of Minnesota Highly illustrated with clinical photographs, diagrams and tables
Download or read book The Chemical Biology of Thrombin written by Roger L. Lundblad and published by CRC Press. This book was released on 2022-05-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of thrombin, especially as regulatory protease. The ready availability of highly purified thrombin has stimulated rapid advances in the cell biology of this important macromolecule. The text focuses on research findings from the discovery of thrombin by Andrew Buchanan in 1842 to the present. A substantial amount of this work was conducted by the author and his colleagues. His work on the purification of thrombin was seminal to much subsequent work on thrombin. This volume provides a framework for future studies now made possible by the discovery of the importance of exosites in the physiology of thrombin function. The current work describes the process of the development of an oral inhibitor of thrombin used in the prevention of thrombosis. Key Features Reviews the history of Thrombin (Fibrin Ferment) Documents the relation of protein engineering and chemical modification in the study of thrombin Summarizes the interaction of thrombin with fibrinogen and fibrin Outlines the role of exosites in thrombin function Describes the development of an oral inhibitor for thrombin
Download or read book Pathobiology of the Endothelial Cell written by Hymie L. Nossel and published by Academic Press. This book was released on 2013-10-22 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathobiology of the Endothelial Cell presents the proceedings of the symposium on the "Pathobiology of the Endothelial Cell" held at Arden House, on the Harriman Campus of Columbia University on June 5-7, 1981. The book discusses the endothelial growth regulation; the stimulation of vascular cell growth by macrophage products; and the control of proliferation and differentiation of endothelial cells. The text also describes vessel wall growth control; the implications of angiogenesis in vitro for tumor biology; and the interactions and activation of coagulation proteases. Platelet adhesion and fibrinogen proteolysis; endothelial protein synthesis; prostaglandins, and endothelial cell-cell interactions are also considered. The book further tackles topics on vascular pathobiology. Biologists, pathologists, biochemists, hematologists, oncologists, immunologists, and microbiologists will find the text invaluable.
Download or read book Handbook of Microsurgery written by Waldemar L. Olszewski and published by CRC Press. This book was released on 2019-06-13 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1984: The premise upon which this book was written was that only and exclusively personal experience in microsurgical operations and their effects on tissue or organ function could be presented.
Download or read book NBC Risks Current Capabilities and Future Perspectives for Protection written by Torsten Sohns and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advanced Research Workshop in Bucharest from 20. to 22. 04. 1998 covered a broad spectrum of medical and pharmaceutical approaches dealing to maintenaning and restoring of the health of civilians and military personnel exposed to ionizing radiation or biological or chemical agents. The current capabilities and future perspectives for protection against NBC hazards were analyzed from an interdisciplinary perspective. In this context the planning of medical support operations was addressed as were aspects of practical medicine and forwardlooking scientific approaches. The main areas covered were: -general approach and NBC risks -pharmacoprotection and treatment -skin protection and decontamination -pharmaceutical aspects of protectants -environmental aspects of NBC disarmament Acknowledgments The editors would like to express their thanks to NATO for having made this publication possible and all the participants of the conference who contributed their publications. In particular, the editors would like to thank Constantin Mircioiu and his staff for their assistance and support during all stages of the conference and editing. In addition, they are grateful to Harald Kempf and his staff for their editorial assistance in preparing this volume. THE PROLIFERATION OF WEAPONS OF MASS DESTRUCTION: HEALTH RISKS -An Analysisfrom a Medical Perspective- T. SOHNS German Armed Forces Medical Academy Neuherbergstr. II, D -80937 Munich Summary: The proliferation of weapons of mass destruction I and long-range means of delivery continues to be a matter of serious concern as it can pose a direct threat to national and international security.
Download or read book Tobacco Smoking and Atherosclerosis written by John N. Diana and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is the principal underlying cause of cardiovascular and cerebrovascular disease in people of the Western world. Cigarette smoking has been implicated in both the initiation and exacerbation of the atherosclerotic process. Data to support this implication derives primarily from epidemiologic studies where the relationship between the incidence of atherosclerosis in people who smoke cigarettes has been shown to have a strong correlation. There are few well established explanations for this phenomenon, and basic molecular, biochemical, and cellular mechanisms associated with smoking and the development of atherosclerosis remain both undefined and virtually unexplored. Even the epidemiologic correlation between cigarette smoking and the development of atherosclerosis needs further critical studies. It is known that individuals who do not smoke cigarettes develop athero sclerosis and it is also known that in people who smoke but have normal or low blood cholesterol/lipoprotein levels, the incidence of development of atherosclerosis is no different from that which is found in a non smoking population. Answers which explain such observations must address fundamental biological mechanisms. Toward this end, the purpose of this volume is to assemble, in a single publication, information which will address the questions; what basic cellular and/or molecular mechanisms are associated with the development of atherosclerosis and how does cigarette smoking influence such mechanisms to initiate or exacerbate the atherosclerotic process? Clearly, the development of atherosclerosis is a complex, multifactorial biological event.
Download or read book Replacement of Renal Function by Dialysis written by William Drukker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: BELDING H. SCRIBNER The year was 1942 and Will em Kolff was hard at 60's, we encountered exactly the same kind of work perfecting the device that would not only resistance to the concept of chronic dialysis. But revolutionize the treatment of renal failure, but as has happened over and over again in all of more importantly point the way to the develop science, the heresy of one decade becomes the ment of the entire field of extracorporeal devices practice of the next - a phenomenon that the in general and cardiac bypass devices in particular. young heretics among the third generation readers The enormity of the impact that Kolffs con of this volume should not forget. tribution was to have on medicine was revealed And so, today Drukker, Parsons and Maher retrospectively to me when I recalled that in that have successfully undertaken the very difficult same year, 1942, I was a second year medical task of bringing together in one volume all the student at Stanford University, taking among diverse elements of dialysis therapy. The size of other things, P. J. Hanzlik's required course in the volume reflects not only the magnitude ofthe pharmacology. I have two memories of that interdisciplinary effort that brought about the course. One was the requirement that we students technical and clinical advances, but also the learn to recognize 64 old time drugs by appear many clinical and other ramifications of dialysis ance, smell and taste. For better or worse, almost therapy.
Download or read book The Prostaglandins written by Peter Ramwell and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.
