Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Nathan Back and published by Springer. This book was released on 2013-12-11 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the first phase, when there is only an inflow from the circulation and stor age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.

Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Nathan Back and published by . This book was released on 2014-09-01 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacology of hormonal polypeptides and proteins written by Nathan Back and published by . This book was released on 1968 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Italy) International Symposium on the Pharmacology of Hormonal Polypeptides (1967: Milan and published by . This book was released on 1968 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Nathan Back and published by . This book was released on with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacology of Hormonal Polypeptides and Proteins Proceedings of an International Symposium written by Nathan Black and published by . This book was released on 1968 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pharmacology of Hormonal Polypeptides and Proteins written by Nathan Back and published by . This book was released on 1968 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Peptide and Protein Hormones written by Dr. Wolfgang König and published by . This book was released on 1993 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Incorporates the developments in the field during the 25 years since the last major overview of peptide and protein hormones. Reviews the most important features of the hormones, including structure/activity relationships. Also describes their medical use, noting that western society encourages an overabundance of aggressive stress hormones, and that the role of doctors is to return them into balance with cooperative sex hormones. Of particular use to researchers, students, and practitioners is a special listing of the hormones according to a network of structural similarity and regulating cascades. Annotation copyright by Book News, Inc., Portland, OR

Download or read book Therapeutic Peptides and Proteins written by Ajay K. Banga and published by CRC Press. This book was released on 1997-07-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Preface At the time of this writing, the American biotechnology and pharmaceutical industry has more than two dozen biotechnology-derived therapeutic proteins on the market, while several hundred are in various stages of human clinical trials or at the FDA for review. Today, more than a thousand companies are involved in biotechnology research, with a total revenue of $7.7 billion for 1993. Therapeutic peptides and proteins are expected to mitigate suffering in coming years as anticancer agents, hormones, growth factors, analgesics, anti-hypertensives, and thrombolytics, among others. However, the clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, and microbiology, and needs to keep abreast with the latest research in the published literature. This book presents these principles in a simple, interesting and practically useful manner for the benefit of scientists working in this area and to further research in this area. This book will also provide useful information for students and academic researchers and add to their interest in this area. The book should also be useful in a hospital setting to understand potential physicochemical stability problems that may result during reconstitution or administration of the new recombinant proteins. Since this field is relatively new and rapidly evolving, efforts were made to include very recent literature in the book. As a result, over 40% of the literature citations in the book are for the work published in the last two years.

Download or read book Hormonal Proteins and Peptides written by Choh Hao Li and published by . This book was released on 1973 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stability and Characterization of Protein and Peptide Drugs written by Rodney Pearlman and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first volume to make available specific case histories of therapeutic proteins and peptides that have been marketed or are currently under clinical testing. The editors have selected a wide range of molecules derived from monoclonal antibodies, recombinant DNA, and natural and chemical sources to provide formulation scientists with practical examples of the development of pharmaceutical products.

Download or read book Peptide Hormones as Prohormones written by Jean Martinez and published by Ellis Horwood. This book was released on 1989 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Structure activity Relationships of Protein and Polypeptide Hormones written by M. Margoulies and published by . This book was released on 1972 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Vitamins and Hormones written by Gerald Litwack and published by Elsevier. This book was released on 2003-09-08 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. - First published in 1943, Vitamins and Hormones is AP's longest running serial - Each volume contains cutting edge reviews by leading contributors

Download or read book Peptide and Protein Hormones written by Wolfgang König and published by Wiley-Blackwell. This book was released on 1993-06-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an up-to-date review on the most interesting features of peptide and protein hormones. It describes the medical uses of hormones and points out structure activity relationships. A particularly useful feature is the special listing of the hormones according to a network of structure similarity and regulating cascades. The main sections are: - Gonadoliberin, Thyroliberin, Gonadotropins, Thyrotropin - Parathyroid Hormone and the Calcitonin Family - Corticoliberin - Proopiomelanocortin Cascade - Blood Pressure Regulating Peptides - Cholecystokinin and Gastrin - Secretin Family with growth hormones, prolactin, insulin and relaxin - Neurotensin - Motilin - Pancreatic Spasmolytic Peptide Students and specialists in peptide chemistry, medicinal chemistry, pharmacology, pharmacy and genetics will find invaluable insights in this book.

Download or read book Peptides written by Bernd Gutte and published by Elsevier. This book was released on 1995-10-24 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. - The history of peptide chemistry - Amide formation, deprotection, and disulfide formation in peptide synthesis - Solid-phase peptide synthesis - a-helix formation by peptides in water - Stability and dynamics of peptide conformation - An overview of structure-function studies of peptide hormones - Neuropeptides:peptide and nonpeptide analogs - Reversible inhibitors of serine proteinases - Design of polypeptides - Current capabilities and future possibilities of soluble chemical combinatorial libraries - Epitope mapping with peptides - Synthesis and applications of branched peptides in immunological methods and vaccines

Download or read book Proteins and Peptides written by Randall J. Mrsny and published by CRC Press. This book was released on 2009-10-19 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is