Download or read book The Peroxidase Multigene Family of Enzymes written by Petro E. Petrides and published by Springer Science & Business Media. This book was released on 2000-08-04 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 1998 experts from 19 countries came together for an interdisciplinary discussion of the function of animal peroxidases, a family of enzymes embracing myeloperoxidase, eosinophil peroxidase, thyroid peroxidase and lactoperoxidase. Their papers have been updated for publication, yielding a wide-ranging overview of the state of the art. The chapters cover a wide range of topics, including three-dimensional structure of representative family members, their biosynthesis and intracellular transport, mechanism of action as well as applications to clinical medicine. They are of clinical relevance in, for example, arteriosclerosis, multiple sclerosis, infections, tumorigenesis, rheumatic diseases and hypothyroidism. This book forms an excellent introduction for anyone interested in the peroxidase family of enzymes.
Download or read book Heme Peroxidases written by Emma Raven and published by Royal Society of Chemistry. This book was released on 2015-10-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life. This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function and mechanism of action. Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. Discussed functions of peroxidases range from cell wall synthesis, synthesis of prostaglandins, role in drug suppression of tuberculosis, and antibacterial activity. Included is a discussion of peroxidases that also act as catalases and oxygenases. Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology.
Download or read book Peroxidases in Chemistry and Biology written by Johannes Everse and published by CRC Press. This book was released on 1990-10-24 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second of two relatively independent volumes on the chemistry and biology of peroxidases. Volumes 2 covers the peroxidases isolated from plants and microorganisms, and includes detailed discussions of some of the unique reactions catalyzed by these enzymes. Volume one covered the peroxidases isolated from animal sources, as well as the "pseudo- peroxidase activity" of prostaglandin H synthase and of myoglobin and hemoglobin. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Monooxygenase Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450 written by Eugene G. Hrycay and published by Springer. This book was released on 2015-05-22 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP19A1 and CYP51A1; metabolism of tetrabromodiphenyl ethers and bile acids by CYP2B6 and CYP3A4; metabolism of ω-6 and ω-3 polyunsaturated fatty acids; H2O2-mediated peroxygenation of substrates using substrate misrecognition; P450 oxidative reactions using electrochemical methods; electron transfer to P450 by redox proteins; hydroxylation of 1,8-cineole by P450cin; and peroxygenation by unspecific peroxygenases using H2O2. The topics covered are relevant to P450 researchers, professors and students from a variety of disciplines ranging from pharmacology, toxicology and microbiology to chemistry.
Download or read book The Biological Chemistry of Iron written by B.H. Dunford and published by Springer Science & Business Media. This book was released on 1982-07-31 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Study Institute, Edmonton, Alberta, Canada, August 23-September 4, 1981
Download or read book Peroxidases and Catalases written by H. Brian Dunford and published by John Wiley & Sons. This book was released on 2010-03-15 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: SINGLE SOURCE GUIDE TO PEROXIDASES AND CATALASES Reflecting the important historical discoveries and exciting research in the field in recent years, Peroxidases and Catalases: Biochemistry, Biophysics, Biotechnology and Physiology provides a much-needed systematic, up-to-date treatment of peroxidases and catalases. From the structure and properties of the various superfamilies to current applications of peroxidases, the book consolidates vast amounts of information previously scattered in the professional literature, covering all aspects of these ubiquitous enzymes that act on a variety of substances and processes in living systems—their properties, reactions, crystal structures, cloning, and more. Considering the subject from both theoretical and applied perspectives, Peroxidases and Catalases offers a critical review of the literature and detailed discussions of the most current research. Chapters cover: The background and history of peroxidases and catalases Plant, fungal, and bacterial peroxidase superfamilies and their organization Mammalian peroxidases including medical and physiological roles Spectroscopic and theoretical techniques for studying peroxidases highlighting the contributions of physicists and physical/theoretical chemists Heme peroxidases, catalases, and other peroxidases such as vanadium and selenium peroxidase Relevant plant and animal physiology This one-stop reference is a vital reference for biochemists, biologists, biochemical engineers, physiologists, environmental and pharmaceutical researchers, and others interested in the study and use of peroxidases and catalases.
Download or read book Recent Insights into the Double Role of Hydrogen Peroxide in Plants written by Naser A. Anjum and published by Frontiers Media SA. This book was released on 2022-02-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biocatalysis Based on Heme Peroxidases written by Eduardo Torres and published by Springer Science & Business Media. This book was released on 2010-08-20 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present recent advances on basic aspects such as evolution, structure–function relation, and catalytic mechanism, as well as applied aspects, such as bioreactor and protein engineering, in order to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. The book does not include an exhaustive listing of references but rather a selected collection to enrich discussion and to allow envisioning future directions for research. This book is organized in three parts. In Part I, current knowledge of structure and mechanism of peroxidases is covered. From the molecular phylogeny, going through the in?uence of structural factors over oxidative ability to the molecular mechanism of catalysis, the authors intend to provide an understanding of per- idases at the molecular level. The understanding of the fundamental behavior of peroxidases will allow further adequation, design, and/or optimization of pero- dase-based catalysis to a particular process. In Part II, research on potential applications of peroxidases in several ?elds is presented and discussed.
Download or read book Mammalian Heme Peroxidases written by Clare Hawkins and published by CRC Press. This book was released on 2021-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well established that peroxidases and their overproduction of oxidants contribute to the initiation and persistence of many chronic inflammatory conditions in the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. Peroxidasins, a protein family related to heme peroxidases, play a novel role in tissue biogenesis and matrix assembly, which are also attracting attention in different pathological contexts. Given the diverse roles of mammalian heme peroxidases and the breadth and incidence of pathologies associated with these enzymes, there has been significant interest in modulating peroxidase activity as a therapeutic strategy. This book highlights recent developments in our understanding of the chemistry, biochemistry and biological roles of mammalian peroxidases and their associated oxidants, their involvement in both innate immunity and chronic inflammatory disease in a variety of end organs, and potential therapeutic approaches to modulate and prevent damaging reactions. Key Features Structure and biosynthesis of mammalian peroxidases Reactivity of hypohalous acids with biological substrates Peroxidases in innate immunity Peroxidases in human pathology Modulation of peroxidase-induced biological damage
Download or read book Horseradish Peroxidase written by Maarten Uzun and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathogenesis Related Proteins in Plants written by Swapan K. Datta and published by CRC Press. This book was released on 1999-04-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of research has been focused on the isolation, characterization, and regulation of expression of pathogenesis-related proteins since the discovery that several of the PR-proteins had antimicrobial or insecticidal activity and can delay the progression of diseases caused by several pathogens belonging to diverse genera. This is an excit
Download or read book Nanozymes Next Wave of Artificial Enzymes written by Xiaoyu Wang and published by Springer. This book was released on 2016-07-27 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
Download or read book Peroxiredoxin Systems written by Leopold Flohé and published by Springer Science & Business Media. This book was released on 2007-09-05 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book highlights related future perspectives.
Download or read book Peroxidases in Chemistry and Biology written by Johannes Everse and published by CRC Press. This book was released on 1990-11-20 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Peroxidases in Chemistry and Biology series provides up-to-date information on a wide range of developments in the field of Peroxidases, methods and applications. This is Volume 1 originally published in 1990.
Download or read book Biocatalysis and Nanotechnology written by Peter Grunwald and published by CRC Press. This book was released on 2017-10-25 with total page 1031 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.
Download or read book Journal of Agricultural Research written by and published by . This book was released on 1916 with total page 1394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanozymes written by Sundaram Gunasekaran and published by CRC Press. This book was released on 2021-11-19 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin–Madison.
