Download or read book Pathways of progression written by Field, Simon and published by UNESCO Publishing. This book was released on 2018-11-12 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathway to Progression written by Khiry Jones and published by . This book was released on 2019-08-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A book that will help you find clarity in the midst of distraction and confusion
Download or read book Inflammatory Tumor Immune Microenvironment Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis written by Xu Wang and published by Frontiers Media SA. This book was released on 2022-03-25 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Microenvironment Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathways and Crime Prevention written by Alan France and published by Routledge. This book was released on 2013-06-17 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with the development of prevention policies and approaches that involve intervention 'early' in the lives of children, young people and their families. This book explores evidence that has been emerging from longitudinal and developmental prevention research.
Download or read book Noncoding RNA in Disease Diagnosis Etiology Progression Prognosis and Treatment written by Sujit Nair and published by Frontiers Media SA. This book was released on 2024-01-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exciting class of regulatory small noncoding RNAs (ncRNAs) has emerged in recent years that play key role(s) in the etiology/pathogenesis and diagnosis/prognosis of various human diseases including various hematologic and solid cancers, cardiovascular diseases including stroke/atherosclerosis, diabetes, obesity, and metabolic disorders, neuropathies, neurodegeneration including Alzheimer’s Disease, Parkinson’s Disease or Multiple Sclerosis, neurological disorders including epilepsy and muscular dystrophies, liver diseases, pulmonary fibrosis, immune-mediated inflammatory disorders and inflammatory bowel disease, gastritis, autoimmune disorders including arthritis, acromegaly, chronic kidney disease, allergic rhinitis, vitiligo, osteoporosis, obstructive sleep apnea, ocular disease, periodontitis, skeletal muscle atrophy, and parasitic diseases including leishmaniasis, amongst others. These ncRNAs include primarily microRNAs (miRNAs), long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), small interfering RNAs (siRNAs) or exosomal RNAs (exRNAs), etc. that modulate the expression of target genes thus potentially regulating protein expression in normal versus diseased individuals. This Research Topic recognizes the importance of and seeks to explore, ncRNAs in the diagnosis, etiology, progression, prognosis, and treatment of human disease as well as novel biomarker discovery by multi-omics technologies and other methodologies. Indeed, high-throughput technologies employing deep sequencing, proteogenomic, microarrays, and quantitative real-time PCR have begun to shed new light on the architecture of ncRNA landscapes in various diseases and key signal transduction cascades modulated by these ncRNAs in disease pathology. Epigenetic control of gene expression mediated via miRNAs, for instance, has expanded our understanding of transcriptional and post-transcriptional regulation of gene expression by critical ncRNAs in the cellular milieu. Network biology approaches including the construction of relevant ncRNA networks, ncRNA-mRNA networks, and bioinformatics for mining of ncRNAs, are gaining greater relevance in the search for ‘target hubs’ or novel biomarker(s) of disease. Delineation of ncRNA signatures by transcriptomic profiling or RNA-seq, for example, is an important milestone in furthering our knowledge of the repertoire of specific ncRNAs implicated in various diseases. Further, elucidation of the specific steps of the signaling cascades where ncRNAs exert their regulatory actions will augment our understanding of diseases. This will lead to the development of (i) a novel biomarker, or biomarker signature panel, for disease; (ii) ncRNA-based companion diagnostics for diagnosis of disease; (iii) point-of-care testing devices based on ncRNAs; (iv) newer therapeutic agents that target novel biomarkers with specificity, thereby reducing toxicity; (v) ncRNA-based prophylactic approaches of the future; and, (vi) ncRNA-based prognosis of disease.
Download or read book Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy written by Pawel Kalinski and published by Springer. This book was released on 2017-12-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.
Download or read book The Canadian Patent Office Record written by Canada. Patent Office and published by . This book was released on 1916 with total page 2200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 365 Days of progress in cancer molecular targets and therapeutics written by Wafik S. El-Deiry and published by Frontiers Media SA. This book was released on 2023-09-26 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathways to the Common Core written by Lucy Calkins and published by Heinemann Educational Books. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lucy Calkins and her colleagues at the Reading and Writing Project have helped thousands of educators design their own pathways to the Common Core. Now, with Pathways to the Common Core, they are ready to help you find your way. Designed for teachers, school leaders, and professional learning communities looking to navigate the gap between their current literacy practices and the ideals of the Common Core, Pathways to the Common Core will help you: understand what the standards say, suggest, and what they don't say; recognize the guiding principles that underpin the reading and writing standards; identify how the Common Core's infrastructure supports a spiraling K-12 literacy curriculum; and scrutinize the context in which the CCSS were written and are being unrolled. In addition to offering an analytical study of the standards, this guide will also help you and your colleagues implement the standards in ways that lift the level of teaching and learning throughout your school.--
Download or read book The Wiley International Handbook on Psychopathic Disorders and the Law written by Alan Felthous and published by John Wiley & Sons. This book was released on 2020-11-24 with total page 1250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The economic impact of society's attempts to rehabilitate and contain psychopathically disordered individuals can be enormous. Understanding the nature of these disorders, developing accurate and valid assessment methods, and providing effective treatment and safe management cannot be underestimated. Including contributions from an international panel of experts from Europe, North America, and Asia, this two-volume set offers an in-depth, multidisciplinary look at key aspects of the development and etiology of psychopathic disorders; current methods of intervention, treatment, and management; and how these disorders impact decision-making in civil and criminal law. The most comprehensive major reference work available on psychopathy and the law, The Wiley International Handbook on Psychopathic Disorders and the Law, 2nd Edition: Covers the full history and conceptual development of psychopathic disorders Provides unique and enlightening perspectives on the subject from some of the world’s most well-renowned professionals in the field Looks at the etiology and pathogenesis of psychopathic disorders Examines current methods for the intervention, treatment, and management of ADHD, antisocial behavior, and impulsive aggression Provides in-depth discussions of civil and criminal law issues The Wiley International Handbook on Psychopathic Disorders and the Law, 2nd Edition is a must-have reference for practitioners and academics in clinical psychology, forensic psychology, psychiatry, probation, law, law enforcement, and social work.
Download or read book Cancer Ecosystems written by Ubaldo E. Martinez-Outschoorn and published by Frontiers Media SA. This book was released on 2019-11-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Canadian Patent Office Record and Register of Copyrights and Trade Marks written by and published by . This book was released on 1915 with total page 1378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for Cardiac Rehabilitation Programs written by AACVPR and published by Human Kinetics. This book was released on 2020-03-04 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guidelines for Cardiac Rehabilitation Programs, Sixth Edition With Web Resource, presents the combined expertise of more than 50 leaders in the field of cardiac rehabilitation (CR), reimbursement, and public policy to empower professionals to successfully implement new CR programs or improve existing ones. Developed by the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), this guidebook offers procedures for providing patients with low-cost, high-quality programming that moves them toward a lifelong commitment to disease management and secondary prevention. Cardiovascular disease (CVD) is the principal cause of death worldwide. It is projected that by 2035, more than 130 million adults in the United States will have CVD. The challenge to CR professionals is to select, develop, and deliver appropriate rehabilitative and secondary prevention services to each patient tailored to their individual needs. Guidelines for Cardiac Rehabilitation Programs, Sixth Edition, is the definitive resource for developing inpatient and outpatient cardiac rehabilitation programs. The sixth edition of Guidelines for Cardiac Rehabilitation Programs equips professionals with current scientific and evidence-based models for designing and updating rehabilitation programs. Pedagogical aides such as chapter objectives, bottom line sections, summaries, and sidebars present technical information in an easy-to-follow format. Key features of the sixth edition include the following: A new chapter on physical activity and exercise that helps readers understand how to develop and implement exercise programs to CVD patients A new chapter on cardiac disease populations that offers readers a deeper understanding of CVD populations, including those with heart valve replacement or repair surgery, left ventricular assist devices, heart transplant, dysrhythmias, and/or peripheral artery disease Case studies and discussion questions that challenge readers to consider how concepts from the text apply to real-life scenarios An expanded web resource that includes ready-to-use forms, charts, checklists, and logs that are practical for daily use, as well as additional case studies and review questions Keeping up with change is a professional necessity and keeping up with the science is a professional responsibility. Guidelines for Cardiac Rehabilitation Programs, Sixth Edition, covers the entire scope of practice for CR programs and professionals, providing evidence-based information on promoting positive lifestyle behavior patterns, reducing risk factors for disease progression, and lessening the impact of CVD on quality of life, morbidity, and mortality. Note: The web resource is included with all new print books and some ebooks. For ebook formats that don’t provide access, the web resource is available separately.
Download or read book Mechanisms of Melanoma Tumor Progression written by Vladimir Spiegelman and published by Frontiers Media SA. This book was released on 2022-02-21 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioinformatics written by Mahmood A. Mahdavi and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics - Trends and Methodologies is a collection of different views on most recent topics and basic concepts in bioinformatics. This book suits young researchers who seek basic fundamentals of bioinformatic skills such as data mining, data integration, sequence analysis and gene expression analysis as well as scientists who are interested in current research in computational biology and bioinformatics including next generation sequencing, transcriptional analysis and drug design. Because of the rapid development of new technologies in molecular biology, new bioinformatic techniques emerge accordingly to keep the pace of in silico development of life science. This book focuses partly on such new techniques and their applications in biomedical science. These techniques maybe useful in identification of some diseases and cellular disorders and narrow down the number of experiments required for medical diagnostic.
Download or read book New Prognostic and Predictive Markers in Cancer Progression written by Susan Costantini Alfredo Budillon and published by MDPI. This book was released on 2021-02-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential biomarkers, based on DNA, RNA, miRNA, protein, and metabolic alterations within cancer cells or tumor microenvironment, that may be combined with clinical and pathological data to greatly improve the prediction of both cancer progression and therapeutic treatment responses. However, in recent years, few biomarkers have progressed from discovery to become validated tools to be used in clinical practice. This Special Issue comprises eight review articles and five original studies on novel potential prognostic and predictive markers for different cancer types.
