Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Download or read book Oxygen Transport to Tissue XXXII written by Joseph C. LaManna and published by Springer Science & Business Media. This book was released on 2011-03-29 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.

Download or read book Oxygen Transport to Tissue XXVII written by Giuseppe Cicco and published by Springer. This book was released on 2014-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the proceedings of the 32nd scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) in Bari, Italy, August 21-26, 2004. It covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special emphasis is placed on methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. The event hosted was a multidisciplinary meeting designed to bring together experts and students from a range of research fields.

Download or read book Oxygen Transport to Tissue II written by Jurgon Grote and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oxygen Transport to Tissue XXIV written by International Society on Oxygen Transport to Tissue. Annual Meeting and published by Boom Koninklijke Uitgevers. This book was released on 2003 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains refereed manuscripts prepared from presentations made at the 27 th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT). The meeting was held in Hanover, NH, USA, at Dartmouth Medical School.

Download or read book Human Hemoglobins written by Howard Franklin Bunn and published by W.B. Saunders Company. This book was released on 1977 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the dawn of the era of molecular biology, hemoglobin has been subjected to more scrutiny than any other protein, and Bunn, Forget, and Ranney can each lay claim to major contributions to the saga of hemoglobin. Their well-organized, comprehensive, and superbly illustrated work is an excellent review of the abnormal hemoglobin field. Early chapters deal with the structure and function of human hemoglobin and the way in which this is modified in various disease states. Later sections deal with the various structural hemoglobin variants and their associated clinical manifestations, the thalassaemias, and the acquired disorders of hemoglobin. The sections that deal with the modification of hemoglobin function in various disease states are particularly good. The book contains an extensive and up-to-date bibliography and is remarkably free from errors of fact or type--the best standard of reference on the subject as of the year 1977.

Download or read book Oxygen Transport to Tissue XXV written by Maureen S. Thorniley and published by Springer Science & Business Media. This book was released on 2003-12-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 30th scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) was held at the Western Conference Centre, UMIST, Manchester, in August 2002. It was attended by some 96 delegates and accompanying persons and there were 128 presentations.

Download or read book Oxygen Transport to Tissue III written by I. Silver and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers which were presented at the Third International Symposium on Oxygen Transport to Tissue together with the discussions at the end of each Session. The meeting was held at Churchill College, Cambridge from July 4th-7th 1977. Our special thanks are due to Mrs. Valerie Jeal and Mr. Charles Drown of the Department of Pathology, Bristol, who were invaluable in ensuring the smooth running of the meeting and the preparation of this book. We are very grateful to Dr. Marian Silver for proof-reading and helping to disentangle the "discussion". We would also express our thanks for the general help received from Janet and Fiona Silver and Steven James and our appreciation of the cheerful assistance of Miss Sadie Williams in putting the finishing touches to the manuscript. August, 1977 I. A. Silver M. Erecinska H. I. Bicher Contents Session 1 - OXYGEN ELECTRODES AND BLOOD MONITORING DEVICES The Bitumen P0 Electrode - A New Method to 2 Manufacture P0 Needle Electrodes 3 2 H. Acker, D. Sylvester, E. Dufau, and H. Durst A Working Equation for Oxygen Sensing Disk Electrodes • • • • • • 9 T. E. Tang, R. E. Barr, V. G. Murphy, and A. W. Hahn Variations on the Response Characteristics of Oxygen Electrodes •••• 17 R. E. Barr, T. E. Tang, and A. W. Hahn Directly Heated Transcutaneous Oxygen Sensor 25 H. P. Kimmich, J. G. Spaan, and F.

Download or read book Basic Physiology for Anaesthetists written by David Chambers and published by Cambridge University Press. This book was released on 2019-07-25 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Physics Pharmacology and Physiology for Anaesthetists written by Matthew E. Cross and published by Cambridge University Press. This book was released on 2014-03-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

Download or read book Structure Function Relationships in Various Respiratory Systems written by Kazuhiro Yamaguchi and published by Springer Nature. This book was released on 2020-07-31 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the morphological backgrounds of various functional parameters of the human respiratory system, including the respiratory control system, dynamics of the upper and lower airways, gas transport and mixing in the lower airways, gas exchange in the acinus, and gas transfer through the alveolar wall. Presenting the latest findings on the interrelationships between morphology and physiology in the respiratory system, the book’s goal is to provide a foundation for further exploring structure-function relationships in various respiratory systems, and to improve both the quality of basic science, and that of clinical medicine targeting the human respiratory system. Edited and written by internationally recognized experts, Structure-Function Relationships in Various Respiratory Systems offers a valuable asset for all physicians and researchers engaging in clinical, physiological, or morphological work in the field of respiration. Moreover, it provides a practical guide for physicians, helping them make more precise pathophysiological decisions concerning patients with various types of lung disease, and will be of interest to respiratory physiologists and respiratory morphologists.

Download or read book The Pathway for Oxygen written by Ewald R. Weibel and published by Harvard University Press. This book was released on 1984 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is rare indeed for one book to be both a first-rate classroom text and a major contribution to scholarship. The Pathway for Oxygen is such a book, offering a new approach to respiratory physiology and morphology that quantitatively links the two. Professionalism in science has led to a compartmentalization of biology. Function is the domain of the physiologist, structure that of the morphologist, and they often operate with vastly disparate concepts and procedures. Yet the performance of the respiratory system depends both on structural and on functional properties that cannot be separated. The first chapter of The Pathway for Oxygen engages the student with the design and function of the vertebrate respiratory organs from a comparative viewpoint. The second chapter adds to that foundation the link between cell energetics and oxygen needs of the whole animal. With Chapter 3 the excitement begins--new ideas, fresh attacks on old problems, and a fuller account of the power of the quantitative approach Dr. Weibel has pioneered. The Pathway for Oxygen will be read eagerly by medical students, graduate students, advanced undergraduates in zoology--and by their professors.

Download or read book Skeletal Muscle Circulation written by Ronald J. Korthuis and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Download or read book Applied Cardiovascular Physiology written by Michael Pinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise yet complete overview of the treatment of cardiovascular instability in the critically ill patient. The authors consider all aspects, ranging from basic physiology and pathophysiology to diagnostic tools and established and novel forms of therapy. The whole is rounded off with an integration of these principles into a series of clinically relevant scenarios.

Download or read book Monitoring Tissue Perfusion in Shock written by Alexandre Augusto Pinto Lima and published by Springer. This book was released on 2018-06-04 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes various aspects of the basic physiological processes critical to tissue perfusion and cellular oxygenation, including the roles of the circulatory system, respiratory system, blood flow distribution and microcirculation. In the context of monitoring critically ill patients in the early hours of circulatory shock, it is essential to recognize changes in traditional parameters such as mean arterial pressure and cardiac output, and to assess the need for active intervention. However, even if global macrocirculatory variables are restored, abnormalities in tissue oxygenation may persist. Tissue hypoperfusion is connected to the development of organ failure and, if it goes unrecognized, may worsen the prognosis. As a result, there is a growing interest in methods for monitoring regional perfusion in peripheral tissues to predict or diagnose ongoing hypoperfusion. In this work, eminent experts from a range of disciplines convey a working knowledge of how regional monitoring in shock can complement the conventional global parameters of oxygen transport, and demonstrate that real-time bedside assessment of tissue oxygenation is readily achievable using noninvasive monitoring techniques. Accordingly, the book offers a valuable, easy-to-use guide for the entire ICU team and other clinicians.

Download or read book Surgical Intensive Care Medicine written by John M. O'Donnell and published by Springer Science & Business Media. This book was released on 2009-11-18 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are honored to present the second edition of Surgical Intensive Care Medicine. Our first edition was considered to be an important contribution to the critical care literature and received excellent reviews from Critical Care Medicine, Chest, and Anesthesiology. In the second edition, the basic organization of the book remains unchanged, being composed of 60 carefully selected chapters divided into 11 sections. The book begins with general topics in primary intensive care, such as airway management and vascular cannulation, followed by categories based on medical and surgical subspecialties. While the chapters discuss definitions, pathophysiology, clinical course, complications, and prognosis, the primary emphasis is devoted to patient management. The contents of the current edition have been comprehensively upgraded and the chapters retained from the first edition have been thoroughly updated, revised, or rewritten. In this second edition, some new topics have been added including Postoperative Care of the Obese Patient, Postoperative Care of the Pancreas Transplant Patient, Optimization of High-Risk Surgical Patients, Post- erative Alcohol Withdrawal Syndrome, Ethics and End of Life Issues, Improving the ICU, and Continuous Medical Education in Intensive Care Medicine. We are extremely fortunate to have high-quality contributors, many of whom are nationally and internationally recognized researchers, speakers, and practitioners in Cri- cal Care Medicine. An important feature of this latest edition is the geographical diversity of its authors. Most are based in the United States, but colleagues from Canada, England, Ireland, Germany, Belgium, Holland, France, Italy, Portugal, and Australia have also made notable contributions.