Download or read book Handbook of Developmental Toxicology written by Ronald D. Hood and published by CRC Press. This book was released on 1996-10-23 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation. This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.
Download or read book Statistics in Toxicology written by Byron J. T. Morgan and published by Oxford University Press. This book was released on 1996 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of papers on aspects of statistics in toxicology is will be of interest to all medical statisticians. It offers findings from numerous leading experts from around the world including A. Whitehead and R. N. Connor (University of Reading), L. Ryan (Harvard), A. P. Grieve (Pfizer Research), K.J. Risko (Northern Telecom), and B.H. Margolin (University of North Carolina). This is the latest in the popular Royal Statistical Society Lecture Series, and will be essential reading for all those involved in this area.
Download or read book Statistical Methods in Toxicology written by Ludwig Hothorn and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected papers from a workshop on modern statistical methods in toxicology held during the EUROTOX '90 conference in Leipzig. The papers deal with the biostatistical evaluation of the commonly used toxicological assays, i.e. mutagenicity, long-term carcinogenicity, embryotoxicity and chronic toxicity assays. The biological background is considered in detail, and most of the related statistical approaches described. In five overview papers, the present state of the art of the related topics is given, while in several contributed papers new approaches are discussed. The most important features are: - A new view on the per-litter analysis problem in em- bryotoxicity assays. - A highly sophisticated treatment of the so-called muta-tox problem in mutagenicity assays. - A detailed discussion of the multiplicity problem based on the closed testing procedure. This volume provides readers with an overview of modern biostatistical methods for several toxicological assays and is in part intended for direct, practical use.
Download or read book Statistics and Experimental Design for Toxicologists Third Edition written by Shayne C. Gad and published by CRC Press. This book was released on 1998-08-14 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a primary text for students of pharmacology, toxicology, and biology, and as a practical handbook to support the daily operations of the toxicology laboratory and researcher. This edition retains the structure of earlier editions, but has been extensively revised to provide both the student and the working toxicologist with the necessary tools for the rigorous and critical design of studies and analysis of experimental data. Assuming only basic mathematical skills as a starting point, Statistics and Experimental Design for Toxicologists provides a thorough and exhaustive introduction to the statistical methods available to and used in the discipline. A worked, practical example from the field is provided for each technique presented. Written from a toxicologist's perspective, this book provides both the methodological tools necessary to analyze experimental toxicology data and the insight to know when to use them.
Download or read book Biostatistics in the Study of Toxicology written by and published by . This book was released on 1994 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Statistics and Experimental Design for Toxicologists and Pharmacologists Fourth Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2005-07-18 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the assumption of basic mathematical skills and knowledge, the author supplies a complete and systematic yet practical introduction to the statistical methodologists available for, and used in, the discipline. For every technique presented, a worked example from toxicology is also presented. See what's new in the Fourth Edition: The first practical guide to performing meta analysis allowing for using the power inherent in multiple similar studies Coverage of Bayesian analysis and data analysis in pharmacology and toxicology Almost 200 problems with solutions Discussion of analysis of receptor binding assays, safety pharmacology assays and other standard types conducted in pharmacology A new chapter explaining the basics of Good Laboratory Practices (GLPs) For those with computer skills, this edition has been enhanced with the addition of basic SAS Written specifically for toxicologists and pharmacologists, the author draws on more than 30 years of experience to provide understanding of the philosophical underpinnings for the overall structure of analysis. The book's organization fosters the ordered development of skills and yet still facilitates ease of access to information as needed. This Fourth Edition gives you the tools necessary to perform rigorous and critical analysis of experimental data and the insight to know when to use them.
Download or read book Bayesian Methods for Measures of Agreement written by Lyle D. Broemeling and published by CRC Press. This book was released on 2009-01-12 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences
Download or read book Encyclopedia of Biopharmaceutical Statistics Four Volume Set written by Shein-Chung Chow and published by CRC Press. This book was released on 2018-09-03 with total page 4031 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug development process, (2) gives a well-balanced summary of current regulatory requirements, and (3) describes recently developed statistical methods in the pharmaceutical sciences. Features of the Fourth Edition: 1. 78 new and revised entries have been added for a total of 308 chapters and a fourth volume has been added to encompass the increased number of chapters. 2. Revised and updated entries reflect changes and recent developments in regulatory requirements for the drug review/approval process and statistical designs and methodologies. 3. Additional topics include multiple-stage adaptive trial design in clinical research, translational medicine, design and analysis of biosimilar drug development, big data analytics, and real world evidence for clinical research and development. 4. A table of contents organized by stages of biopharmaceutical development provides easy access to relevant topics. About the Editor: Shein-Chung Chow, Ph.D. is currently an Associate Director, Office of Biostatistics, U.S. Food and Drug Administration (FDA). Dr. Chow is an Adjunct Professor at Duke University School of Medicine, as well as Adjunct Professor at Duke-NUS, Singapore and North Carolina State University. Dr. Chow is the Editor-in-Chief of the Journal of Biopharmaceutical Statistics and the Chapman & Hall/CRC Biostatistics Book Series and the author of 28 books and over 300 methodology papers. He was elected Fellow of the American Statistical Association in 1995.
Download or read book Explanatory Item Response Models written by Paul de Boeck and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume gives a new and integrated introduction to item response models (predominantly used in measurement applications in psychology, education, and other social science areas) from the viewpoint of the statistical theory of generalized linear and nonlinear mixed models. It also includes a chapter on the statistical background and one on useful software.
Download or read book Oxford Textbook of Global Public Health written by Roger Detels and published by Oxford University Press. This book was released on 2017 with total page 1717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1997 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Models for Discrete Longitudinal Data written by Geert Molenberghs and published by Springer Science & Business Media. This book was released on 2006-08-30 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The linear mixed model has become the main parametric tool for the analysis of continuous longitudinal data, as the authors discussed in their 2000 book. Without putting too much emphasis on software, the book shows how the different approaches can be implemented within the SAS software package. The authors received the American Statistical Association's Excellence in Continuing Education Award based on short courses on longitudinal and incomplete data at the Joint Statistical Meetings of 2002 and 2004.
Download or read book Biostatistics written by I.B. MacNeill and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: On May 27-31, 1985, a series of symposia was held at The University of Western Ontario, London, Canada, to celebrate the 70th birthday of Pro fessor V. M. Joshi. These symposia were chosen to reflect Professor Joshi's research interests as well as areas of expertise in statistical science among faculty in the Departments ofStatistical and Actuarial Sciences, Economics, Epidemiology and Biostatistics, and Philosophy. From these symposia, the six volumes which comprise the "Joshi Festschrift" have arisen. The 117 articles in this work reflect the broad interests and high quality of research of those who attended our conference. We would like to thank all of the contributors for their superb cooperation in helping us to complete this project. Our deepest gratitude must go to the three people who have spent so much of their time in the past year typing these volumes: Jackie Bell, Lise Constant, and Sandy Tarnowski. This work has been printed from "camera ready" copy produced by our Vax 785 computer and QMS Lasergraphix printers, using the text processing software TEX. At the initiation of this project, we were neophytes inthe use ofthis system. Thank you, Jackie, Lise, and Sandy, for having the persistence and dedication needed to complete this undertaking.
Download or read book Mortality and Migration in the Modern World written by Ralph Shlomowitz and published by Taylor & Francis. This book was released on 2024-10-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term 'relocation cost' has been coined by Philip Curtin to refer to the increased mortality associated with the migration of people from their childhood disease environments to new ones. He and others have quantified this cost for a number of migrant populations, notably Africans in the transatlantic slave trade and European tropps posted overseas. The papers in this volume, extend this research agenda by quantifying and analyzing the mortality suffered by other migrant groups, both on their voyage and after their arrival at their destination. The first three studies deal with free and convict European migration to Australia; the following ones with movements of indentured labour, from the mid 19th to the present century: Chinese, African, Pacific Islander, and above all the migration of Indian labour across half of the globe. The collection is introduced by a new essay, setting out the historical context and significance of this research.
Download or read book Analysis of Quantal Response Data written by Byron J.T. Morgan and published by CRC Press. This book was released on 2018-12-13 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes the standard methods as the starting point, and then describes a wide range of relatively new approaches and procedures designed to deal with more complicated data and experiments - including much recent research in the area. Throughout mention is given to the computing requirements - facilities available in large computing packages like BMDP, SAS and SPSS are also described.
Download or read book Design and Analysis of Animal Studies in Pharmaceutical Development written by Shein-Chung Chow and published by CRC Press. This book was released on 1998-01-15 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides well-integrated, comprehensive coverage of all the major statistical designs and methods used for animal studies in pharmaceutical research and development. Demonstrates the correct way to interpret the results of animal studies in the risk assessment of biopharmaceutical products and clarifies detailed presentations with real-world examples. "
Download or read book Chemical Hazards to Human Reproduction written by and published by . This book was released on 1981 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
