Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.

Download or read book Davis s Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Download or read book Nitroglycerin 8 written by H. C. Mehmel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 8".

Download or read book TALLARIDA TOP 200 written by TALLARIDA and published by Springer. This book was released on 1981-12-21 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nitrates III written by P. Lichtlen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological and clinical research on nitrates continues to be of growing interest in many centers. This is surprising in view of the fact that their favorable effects in angina pectoris were described by Brunton and by Murrell in the Lancet more than 100 years ago. As expected, a host of new information has been collected since the two previous symposia on nitrates held in Stockholm in 1975 and Berlin in 1978. New insights were gained into the pharmacology, pharmacokinetics and pharmacodynamics of nitrates, as well as into their clinical effects in acute and chronic ischemic heart diseases and in severe congestive heart failure. Relatively little progress, however, was observed in research into the basic action of nitrates. Although most investigators agree that intracellular sequestration of calcium is probably the main mechanism by which nitrates lead to the reduction of vascular smooth muscle tone, the exact site of their action still remains undefined. In contrast, dose-dependent differences in venous and arteriolar tone have long been clearly established. Treatment was again in the main stream of discussion. The question of tolerance following long-term administration was discussed in depth and the term "pseudotolerance" was introduced to describe the adaptation of the body's circulatory system to chronic vasodilation. This is especially important in long term prophylactic antiischemic treatment in stable, as well as in unstable angina pectoris (i.e. during increased vasomotor tone - spasm).

Download or read book Nitroglycerin 9 written by Thomas Meinertz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 9".

Download or read book Textbook of Therapeutics written by Richard A. Helms and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 2773 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this volume deliver information on latest drug treatments and therapeutic approaches for a wide range of diseases and conditions. Coverage includes discussion of racial, ethnic, and gender differences in response to drugs and to biotechnical, pediatric and neonatal therapies.

Download or read book Nitroglycerin 6 written by H. Roskamm and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 6".

Download or read book Nitroglycerin 5 written by Bodo E. Strauer and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-10-08 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 5".

Download or read book Nitroglycerin 7 written by P. G. Hugenholtz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-08 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 7".

Download or read book Commercial Organic Analysis pt I Fixed oils fats waxes glycerol nitroglycerin and nitroglycerin explosives 3d ed with revisions and addenda by the author and Henry Leffmann 1899 written by Alfred Henry Allen and published by . This book was released on 1899 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Behavior of Nitroglycerin when Heated written by Walter Otheman Snelling and published by . This book was released on 1912 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nitrate Esters Chemistry and Technology written by Jiping Liu and published by Springer. This book was released on 2019-03-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea of this book is to present the up-to-date research results on Nitrate Esters as explosive materials. It covers many aspects including the material structures, nitrating agent, chemical synthesis devices, preparation technology, and applications etc. In particular, this work sheds light on the comprehensive utilization and thorough destruction of the used Nitrate Easters which is crucial for preventing repeated pollution. This is a highly informative and instructive book providing insight for the researchers working on nitrating theory, energetic materials and chemical equipments.

Download or read book Understanding the Benefits Risks of sustained delivery of Nitroglycerin on Cardiomyocyte viability following Ischemia written by DR .HAKIM SABOOWALA and published by Dr.Hakim Saboowala. This book was released on 2019-07-02 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin remains a first-line treatment for angina pectoris and acute myocardial infarction. · Nitroglycerin achieves its benefit by giving rise to nitric oxide, which causes vasodilation and increases blood flow to the myocardium. However, continuous delivery of nitroglycerin results in tolerance, limiting the use of this drug. Nitroglycerin tolerance is due, at least in part, to inactivation of aldehyde dehydrogenase 2 (ALDH2), an enzyme that converts nitroglycerin to the vasodilator, nitric oxide. Researchers have recently found that, in addition to nitroglycerin’s effect on the vasculature, sustained treatment with nitroglycerin negatively affects cardiomyocyte viability following ischemia, thus resulting in increased infarct size in a myocardial infarction model in animals. Co-administration of Alda-1, an activator of ALDH2, with nitroglycerin improves metabolism of reactive aldehyde adducts and prevents the nitroglycerin-induced increase in cardiac dysfunction following myocardial infarction. An attempt has been made as usual for the enthusiastic medicos in this Booklet to describe the molecular mechanisms associated with the benefits and risks of nitroglycerin administration in myocardial infarction. …….Dr.H.K.Saboowala.M.B.(Bom) M.R.S.H.(London)

Download or read book Occupational exposure to nitroglycerin and ethylene glycol dinitrate written by National Institute for Occupational Safety and Health and published by . This book was released on 1978 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Factors Affecting Detonation Velocities of Desensitized Nitroglycerin in Simulated Underground Fractures written by and published by . This book was released on 1969 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Commercial Organic Analysis pt I Fixed oils fats waxes glycerol nitroglycerin and nitroglycerin explosives 3d ed with revisions and addenda by the author and Henry Leffmann 189 written by Alfred Henry Allen and published by . This book was released on 1900 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: