Download or read book Neural Tracing Methods written by Benjamin R. Arenkiel and published by Humana. This book was released on 2016-09-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume seeks to familiarize readers with a diverse range of technologies and approaches for probing neuron and circuit architecture, and, when possible, to attach detailed protocols to help guide readers toward practical application. From classical lipophilic dye and conjugated lectin tracing techniques, to electrophysiological, in vivo imaging, viral tract tracing, and emerging genetic methods to mark, manipulate, and monitor neural circuits, Neural Tracing Methods: Tracing Neurons and Their Connections includes reference to an arsenal of tools and technologies currently being implemented in model systems ranging from flies to mice. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Essential and authoritative, Neural Tracing Methods: Tracing Neurons and Their Connections collects a comprehensive compilation of chapters authored by inventors and expert users, that describes state-of-the-art neuronal tracing and functional analysis methods in order to aid researchers in continuing this vital pathway of study.
Download or read book Neuroanatomical Tract Tracing written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.
Download or read book Neuroanatomical Tract Tracing Methods 2 written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition presents readers with the latest information on neuroscience. This book explores the advances in molecular techniques, genomics and proteomics and the progress in fluorescence.
Download or read book Neurobiology of the Locus Coeruleus written by and published by Elsevier. This book was released on 1991-11-21 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of the Locus Coeruleus
Download or read book Viral Vector Design and Lensless Imaging for Neural Tracing written by Shuyang Zhang and published by . This book was released on 2021 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal tracing methods are essential tools to understand the fundamental architecture of the neural circuits and their connection to the overall functional behavior of the brain. Various viral vectors have been developed to achieve cell-type specific and directional specific labeling of the neuronal connections. The incorporation of the viral tracers with optogenetics techniques can further provide precise control over the viral propagation. Herein, a novel approach to guide the infectious pattern of the Rabies Virus (RV) retrograde tracer with light is described. The key concept is to use Baculovirus (BV) as a helper virus to deliver all the functional components prior to the rabies infection. These functional components include the optogenetic tool parts, a fluorescent CRE reporter to mark RV infected cells, and other genes necessary for RV spread. GoldenGate DNA assembly method was used to efficiently construct three large BV expression cassettes in bacteria plasmids that can be transposed into the baculovirus genome in a single TN7 transposon recombination step. The actual imaging of BV and RV infected cells and stimulation of optogenetics tools for the spread of RV can be achieved with CMOS sensor and OLED display panels. By integrating these commercially available electronics with proper microcontrollers, a synchronized communication protocol for optogenetic stimulation, image capturing, and file transferring was established in a lensless imaging setup. The OLED and CMOS sensor's large field of view and low cost allows this tracing method to scale many orders of magnitude greater than using microscopy-based methods.
Download or read book Mapping the Brain and Its Functions written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in brain research have been made, but investigators who face the resulting explosion of data need new methods to integrate the pieces of the "brain puzzle." Based on the expertise of more than 100 neuroscientists and computer specialists, this new volume examines how computer technology can meet that need. Featuring outstanding color photography, the book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain, and schizophrenia are highlighted. The committee explores the potential benefits of computer graphics, database systems, and communications networks in neuroscience and reviews the available technology. Recommendations center on a proposed Brain Mapping Initiative, with an agenda for implementation and a look at issues such as privacy and accessibility.
Download or read book Neuroscience and Neurotechnology of Neuronal Cell Surface Molecules in Neural Circuits written by Masahito Yamagata and published by Frontiers Media SA. This book was released on 2021-08-05 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tracing Neural Connections with Horseradish Peroxidase written by M.-Marsel Mesulam and published by John Wiley & Sons. This book was released on 1982 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surveys methods for tracing neural connections with the tracer horseradish peroxidase. Discusses light-microscopic tracing following extracellular injections of tracer. Describes electron microscopic applications of horseradish peroxidase histochemistry for tracing neural connections, and compares various histochemical methods. Also discusses tracing connections after intracellular injections of HRP into physiologically identified neurons. Fully treats the relevant biological principles which guide each application
Download or read book 2021 IEEE 18th International Symposium on Biomedical Imaging ISBI written by IEEE Staff and published by . This book was released on 2021-04-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging ISBI 2021 will be the 18th meeting in this series The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging The 2021 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation
Download or read book Computational Neuroanatomy written by Giorgio A. Ascoli and published by Springer Science & Business Media. This book was released on 2002-07-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
Download or read book Micro Meso and Macro Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Download or read book Fiber Pathways of the Brain written by Jeremy D. Schmahmann and published by OUP USA. This book was released on 2009-02-11 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text is enriched throughout by close attention to functional aspects of the anatomical observations."--Jacket.
Download or read book Current Laboratory Methods in Neuroscience Research written by Huangui Xiong and published by Springer. This book was released on 2016-08-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
Download or read book The Human Nervous System written by George Paxinos and published by Academic Press. This book was released on 2012-12-02 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Nervous System is a definitive account of human neuroanatomy, with a comprehensive coverage of the brain, spinal cord, and peripheral nervous system. The cytoarchitecture, chemoarchitecture, connectivity, and major functions of neuronal structures are examined by acknowledged authorities in the field, such as: Alheid, Amaral, Armstrong, Beitz, Burke, de Olmos, Difiglia, Garey, Gerrits, Gibbins, Holstege, Kaas, Martin, McKinley, Norgren, Ohye, Paxinos, Pearson, Pioro, Price, Saper, Sasaki, Schoenen, Tadork, Voogd, Webster, Zilles, and their associates. - Large, clearly designed 8-1/2" x 11" format - 35 information-packed chapters - 500 photomicrographs and diagrams - 6,200 bibliographic entries - Table of contents for every chapter - Exceptionally cross-referenced - Detailed subject index - Substantial original research work - Mini atlases of some brain regions
Download or read book The NEURON Book written by Nicholas T. Carnevale and published by Cambridge University Press. This book was released on 2006-01-12 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press. This book was released on 2015-02-25 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.
Download or read book A Handbook of Process Tracing Methods written by Michael Schulte-Mecklenbeck and published by Routledge. This book was released on 2019-06-10 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Handbook of Process Tracing Methods demonstrates how to better understand decision outcomes by studying decision processes, through the introduction of a number of exciting techniques. Decades of research have identified numerous idiosyncrasies in human decision behavior, but some of the most recent advances in the scientific study of decision making involve the development of sophisticated methods for understanding decision process—known as process tracing. In this volume, leading experts discuss the application of these methods and focus on the best practices for using some of the more popular techniques, discussing how to incorporate them into formal decision models. This edition has been expanded and thoroughly updated throughout, and now includes new chapters on mouse tracking, protocol analysis, neurocognitive methods, the measurement of valuation, as well as an overview of important software packages. The volume not only surveys cutting-edge research to illustrate the great variety in process tracing techniques, but also serves as a tutorial for how the novice researcher might implement these methods. A Handbook of Process Tracing Methods will be an essential read for all students and researchers of decision making.
