Download or read book Multiscale Modeling to Tackle the Complexity of Load Bearing Organ and Tissue Regulation written by Jerome Noailly and published by Frontiers Media SA. This book was released on 2022-03-11 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multiscale Cancer Modeling written by Thomas S. Deisboeck and published by CRC Press. This book was released on 2010-12-08 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Download or read book Multiscale Modeling of Cancer written by Vittorio Cristini and published by Cambridge University Press. This book was released on 2010-09-09 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
Download or read book Multiscale Modeling and Simulation of Composite Materials and Structures written by Young Kwon and published by Springer Science & Business Media. This book was released on 2007-12-04 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state-of-the-art in multiscale modeling and simulation techniques for composite materials and structures. It focuses on the structural and functional properties of engineering composites and the sustainable high performance of components and structures. The multiscale techniques can be also applied to nanocomposites which are important application areas in nanotechnology. There are few books available on this topic.
Download or read book Practical Aspects of Computational Chemistry written by Jerzy Leszczynski and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads.
Download or read book Mechanobiology written by Glen L. Niebur and published by Elsevier. This book was released on 2019-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena
Download or read book Dexterity and Its Development written by Nicholai A. Bernstein and published by Psychology Press. This book was released on 2014-04-04 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a very unusual book. It brings to the English speaking reader a masterpiece written some 50 years ago by one of the greatest minds of the 20th century--Nicholai Aleksandrovich Bernstein--considered the founder of many contemporary fields of science such as biomechanics, motor control, and physiology of activity. Divided into two parts, this volume's first section is a translation of the Russian book On Dexterity and Its Development. It presents, in a very reader-friendly style, Bernstein's major ideas related to the development and control of voluntary movements in general, and to the notion of dexterity, in particular. Although very few scientific works remain interesting to the reader 50 years after they were written, this volume--now available for the first time in English--is a rare exception to this rule. His ideas are certainly not obsolete. Actually, we are just starting to grasp the depth and breadth of his thinking, especially his analysis of the complex notion of dexterity. The second section provides both a historical and a contemporary perspective on Bernstein's ideas. The original work was directed at a wide audience ranging from specialists in biomechanics and motor behavior, to coaches, neurologists, physical therapists, athletes, and even inquisitive college and high school students. The chapters contributed by contemporary scientists mirror Bernstein's style and present new findings in the areas of biomechanics, motor control, and motor development in a way that would be both understandable to non-specialists in these areas, and informative for professionals working in different areas related to human movement. All those interested in the origins and mechanisms of the production of voluntary movements, irrespective of their educational and professional background, will find this book valuable. In addition, the unique history and composition of this text will make it helpful and attractive to historians and philosophers of science.
Download or read book Bioinspired Structures and Design written by Wole Soboyejo and published by Cambridge University Press. This book was released on 2020-09-17 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master simple to advanced biomaterials and structures with this essential text. Featuring topics ranging from bionanoengineered materials to bio-inspired structures for spacecraft and bio-inspired robots, and covering issues such as motility, sensing, control and morphology, this highly illustrated text walks the reader through key scientific and practical engineering principles, discussing properties, applications and design. Presenting case studies for the design of materials and structures at the nano, micro, meso and macro-scales, and written by some of the leading experts on the subject, this is the ideal introduction to this emerging field for students in engineering and science as well as researchers.
Download or read book Feedback Systems written by Karl Johan Åström and published by Princeton University Press. This book was released on 2021-02-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory
Download or read book Biomaterials for Implants and Scaffolds written by Qing Li and published by Springer. This book was released on 2016-11-30 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.
Download or read book Cardiovascular Solid Mechanics written by Jay D. Humphrey and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.
Download or read book Tissue Engineering for Artificial Organs 2 Volume Set written by Anwarul Hasan and published by John Wiley & Sons. This book was released on 2017-06-19 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.
Download or read book Skeletal Muscle Repair and Regeneration written by Stefano Schiaffino and published by Springer Science & Business Media. This book was released on 2008-01-18 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.
Download or read book Material Parameter Identification and Inverse Problems in Soft Tissue Biomechanics written by Stéphane Avril and published by Springer. This book was released on 2016-10-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles in this book review hybrid experimental-computational methods applied to soft tissues which have been developed by worldwide specialists in the field. People developing computational models of soft tissues and organs will find solutions for calibrating the material parameters of their models; people performing tests on soft tissues will learn what to extract from the data and how to use these data for their models and people worried about the complexity of the biomechanical behavior of soft tissues will find relevant approaches to address this complexity.
Download or read book Principles of Multiscale Modeling written by Weinan E and published by Cambridge University Press. This book was released on 2011-07-07 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: A systematic discussion of the fundamental principles, written by a leading contributor to the field.
Download or read book Converging Technologies for Improving Human Performance written by Mihail C. Roco and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.
Download or read book Multiscale Modelling and Simulation written by Sabine Attinger and published by Springer Science & Business Media. This book was released on 2004-07-12 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In August 2003, ETHZ Computational Laboratory (CoLab), together with the Swiss Center for Scientific Computing in Manno and the Università della Svizzera Italiana (USI), organized the Summer School in "Multiscale Modelling and Simulation" in Lugano, Switzerland. This summer school brought together experts in different disciplines to exchange ideas on how to link methodologies on different scales. Relevant examples of practical interest include: structural analysis of materials, flow through porous media, turbulent transport in high Reynolds number flows, large-scale molecular dynamic simulations, ab-initio physics and chemistry, and a multitude of others. Though multiple scale models are not new, the topic has recently taken on a new sense of urgency. A number of hybrid approaches are now created in which ideas coming from distinct disciplines or modelling approaches are unified to produce new and computationally efficient techniques.
