Download or read book Metabolic Aspects of Alcoholism written by Charles S. Lieber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first annual report on Alcohol and. Health to Congress (December, 1971), the then HEW Secretary Elliot L. Richardson called alcohol 'the most abused drug in the United States'. The report revealed that nine million Americans are alcohol abusers and that alcoholic individuals represent almost 10 % of the nation's work force. With spreading alcoholism, the incidence of physical damage due to alcohol has greatly increased. A question which is often raised is 'in which way does an alcoholic differ from a non-alcoholic?' Inquiries have focused on psychological make-up, behavioural differences and socioeconomic factors. More recently, however, physical differences have been delineated. Prior to the development of various disease entities, chronic ethanol exposure results in profound biochemical and morphological changes. Consequently an alcoholic does not respond normally to alcohol, or other drugs or even other toxic agents. Some of these persistent biochemical and morphological changes are the consequences of the injurious effects of ethanol, whereas others may represent the possible adaptive responses to the profound changes in intermediary metabolism which are a direct and im mediate consequence of the oxidation of ethanol itself. Differentiation between the effects of ethanol directly linked to its oxidation, and the adaptive and injurious effects of ethanol are not simple, and overlap is common. In general, however, metabolic effects are associated with the presence of relatively low ethanol concentrations, whereas injurious effects occur with high ethanol concentrations and/or after prolonged intake. High ethanol con centrations also produce so-called pharmacological effects.
Download or read book Alcohol Metabolism Alcohol Intolerance and Alcoholism written by Dharam P. Agarwal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.
Download or read book The Pharmacology of Alcohol and Alcohol Dependence written by Henri Begleiter and published by Oxford University Press, USA. This book was released on 1996 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
Download or read book Metabolic Effects of Alcohol written by Pietro Avogaro and published by . This book was released on 1979 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: A comprehensive view of the use and abuse of alcohol, from social, genetic, and metabolic standpoints, ispresented. The 6 major areas covered are: effects on society and health; interaction with the endocrine system; interaction with drugs; effects on lipids and lipoproteins; liver function and pathology; and effects on the renal and cardiovascular systems. Specific topics include analyses of alcohol and its biochemical pathways in the body. Data from animal experiments and human observations reflect the effects of ethanol on regulation of triacylglycerol synthesis, growth hormone, and prolactin secretion. The changing perceptions toward alcohol are illustrated by emerging information on possible nutritional options, such as lipoprotein alterations which result in increased HDL levels and VLDL turnover, and seem to be associated with some protection against the risk of coronary heart disease. While small amounts of alcohol seem beneficial in gastrointestinal and pancreatic functions, excessive ingestion presents dangerous implications for pregnancy, thegonadal system, central nervous system, liver functions, etc.
Download or read book Human Metabolism of Alcohol Volume I written by Kathryn E. Crow and published by CRC Press. This book was released on 1989-04-30 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume text provides a comprehensive review and reference source for those with a teaching, research, or practical involvement in alcohol metabolism in humans. Written by 70 contributing authors from 12 countries, this publication covers a wide range of material, from medicolegal aspects of alcohol metabolism to the structure of enzymes involved in metabolizing alcohol. Although primarily concerned with human alcohol metabolism, information from animal experiments is included where it clarifies results of human studies, or where information for human subjects is not available.
Download or read book The Genetics of Alcoholism written by Henri Begleiter and published by Alcohol and Alcoholism. This book was released on 1995 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.
Download or read book Nutritional and Other Metabolic Aspects written by and published by . This book was released on 1983 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bibliography includes literature published since 1977 on general nutritional and other metabolic aspects related to alcohol use or alcoholism. Latest update Oct. 1983.
Download or read book Drug Metabolism and Alcohol written by R. C. Pirola and published by . This book was released on 1978 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Effects of Alcohol written by P. Avogaro and published by Elsevier-North-Holland Biomedical Press. This book was released on 1979-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Committee on Problems of Alcohol written by Jonathan O. Cole and published by National Academies. This book was released on 1956 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Public Policy written by National Research Council and published by National Academies Press. This book was released on 1981-02-01 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolic Effects of Alcohol written by Vincent Marks and published by . This book was released on 1978 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol in America written by United States Department of Transportation and published by National Academies Press. This book was released on 1985-02-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol is a killerâ€"1 of every 13 deaths in the United States is alcohol-related. In addition, 5 percent of the population consumes 50 percent of the alcohol. The authors take a close look at the problem in a "classy little study," as The Washington Post called this book. The Library Journal states, "...[T]his is one book that addresses solutions....And it's enjoyably readable....This is an excellent review for anyone in the alcoholism prevention business, and good background reading for the interested layperson." The Washington Post agrees: the book "...likely will wind up on the bookshelves of counselors, politicians, judges, medical professionals, and law enforcement officials throughout the country."
Download or read book Biological Aspects of Alcoholism written by Boris Tabakoff and published by . This book was released on 1995 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therefore this volume is invaluable for a wide range of treatment professionals, health care and law enforcement managers and policy makers, as well as for researchers involved with the biomedical and psychosocial consequences of alcoholism. Medically-oriented lay readers will also find this book to be a refreshingly direct and authoritative review of the field.
Download or read book The Biology of Alcoholism written by Benjamin Kissin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers neurophysioligcal and psychological effects of alcohol on man. Includes extensive bibliographies covering the literature from 1920 through 1970.
Download or read book Variceal Hemorrhage written by Roberto de Franchis and published by Springer Science & Business Media. This book was released on 2014-01-25 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
