Download or read book Brain Metastases written by Jeffrey Raizer and published by Springer Science & Business Media. This book was released on 2007-10-03 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.
Download or read book Brain Metastases from Primary Tumors Volume 1 written by M. A. Hayat and published by Academic Press. This book was released on 2014-04-03 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. The only comprehensive reference detailing the link between primary cancers and brain metastases Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain Documents temporal and gender-related trends in brain metastases from other cancers Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
Download or read book Central Nervous System Metastases written by Rohan Ramakrishna and published by Springer Nature. This book was released on 2020-05-27 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.
Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.
Download or read book Brain Metastases from Primary Tumors Volume 3 written by M. A. Hayat and published by Academic Press. This book was released on 2016-04-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood. Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book. The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers.
Download or read book Brain Metastases written by Jeffrey J. Raizer and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.
Download or read book Intracranial Metastases written by Raymond Sawaya and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive textbook on intracranial metastases in over 20 years with an update on current methods for their management, including the use of newer technologies. Each of the various histological types of cancer metastasizing to the brain is presented separately in a detailed analysis and discussion. This volume includes a consideration of the epidemiology of brain metastases and the quality of life in patients who have them. Special topics not previously covered are reviewed, including metastasis to the skull base and strategies for preventing cancer from metastasizing to the brain. A novel feature is a chapter devoted to the use of recent techniques such as functional magnetic resonance (MR) imaging, MR spectroscopy (metabolite mapping), and dynamic susceptibility contrast imaging (regional cerebral blood volume mapping) to characterize brain metastases in terms of the sensorimotor perturbations they produce, their metabolic response to therapy, and their degree of vascularization, respectively.
Download or read book Brain Metastasis written by L. Weiss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of those people dying with cancer, many die as a result of metastases. In spite of this, a surprisingly small number of texts have been devoted to this clinically important topic. The present series of monographs originated in discussions, which convinced us of the need for texts on metasasis which would contain not only basic and clinical observations on human beings and where neces sary, on experimental animals but also discussions of the state of the art in diagnosis and therapy. In order to achieve this in-depth approach, for which publication was preceded by small workshops, it was necessary to impose limitations on the scope of the topic. Metastasis is therefore dis cussed by site, and the series is organized accordingly. The first volume in the series, Pulmonary Metastasis, was an expanded version of a Workshop held at Roswell Park Memorial Institute in 1977. This, the second volume, is based on a similar workshop on metastasis to the brain, held at the Memorial Sloan-Kettering Cancer Center in September, 1978. In organiz ing both the workshop and in editing this volume, we have been excep tionally fortunate to receive the generous cooperation of Dr. Jerome B. Posner, a practicing neurologic oncologist who has given freely of his ex pertise in this specialized field.
Download or read book Hybrid PET MR Neuroimaging written by Ana M. Franceschi and published by Springer Nature. This book was released on 2021-11-30 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no standard resource summarizing the vast information and its potential applications. This book will guide neurological molecular imaging applications in both clinical practice and the research setting. Experts from multiple disciplines, including radiologists, researchers, and physicists, have collaborated to bring their knowledge and expertise together. Sections begin by covering general considerations, including public health and economic implications, the physics of PET/MR systems, an overview of hot lab and cyclotron, and radiotracers used in neurologic PET/MRI. There is then coverage of each major disease/systemic category, including dementia and neurodegenerative disease, epilepsy localization, brain tumors, inflammatory and infectious CNS disorders, head and neck imaging, as well as vascular hybrid imaging. Together, we have created a thorough, concise and up-to-date textbook in a unique, user-friendly format. This is an ideal guide for neuroradiologists, nuclear medicine specialists, medical physicists, clinical trainees and researchers.
Download or read book Contemporary Management of Intracranial Metastatic Disease written by Sunit Das and published by Frontiers Media SA. This book was released on 2019-10-17 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of intracranial metastatic disease (IMD) complicates the course of 20% of patients with cancer. Despite improvements in patient survival with more aggressive treatment options as compared to the prior standard of palliative whole brain radiation, outcomes for patients who develop IMD remain dispiriting. There is need to celebrate our advances; but a major collaborative multidisciplinary effort is needed to push the field to achieve more meaningful survival benefits for our patients with IMD. In this Research Topic collection, we have assembled work detailing the latest innovations in brain metastases imaging and management, spanning from minimally invasive surgery to immunotherapy. We hope that you find it a valuable resource.
Download or read book HER2 Positive Breast Cancer written by Sara Hurvitz and published by Elsevier Health Sciences. This book was released on 2018-07-26 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.
Download or read book Metastases to the Central Nervous System An Issue of Neurosurgery Clinics of North America written by Edjah K. Nduom and published by Elsevier Health Sciences. This book was released on 2020-09-24 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
Download or read book Brain Metastases written by Mikhail Dolgushin and published by Springer. This book was released on 2017-10-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of advanced neuroimaging techniques in characterizing the changes in tissue structure in patients with brain metastases. On a large number of newly recognized CT, MRI, and PET characteristics of brain metastases from different primary tumors are highlighted, thereby elucidating the potential differential diagnostic role of CT perfusion imaging, MR spectroscopy, MR diffusion-weighted imaging, MR susceptibility-weighted imaging, and PET with different radiopharmaceuticals. For example, the different manifestations of metastases of melanoma, renal cell carcinoma, and ovarian cancer on MRI and CT perfusion imaging are described, and the role of MR susceptibility-weighted imaging in the differential diagnosis of glioblastoma multiforme and metastatic tumors is clarified. Metastases of colon cancer have shown a special manifestation on T2 weighted images. The book also presents novel findings regarding pathogenesis and tumor biology and describes qualitative and quantitative changes in tumor tissue and alterations in brain white matter due to surrounding tumor growth. Neuroradiologists and others, including neurosurgeons, neurologists, and nuclear medicine physicians, will find that this book offers a fascinating insight into the ways in which newly available data on structural, hemodynamic, and metabolic changes are enriching the neuroimaging of brain metastases.
Download or read book Introduction to Cancer Metastasis written by Aamir Ahmad and published by Academic Press. This book was released on 2016-11-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives. Includes basic biology and translational approaches to organ-specific cancer sites Provides readers with information on emerging therapeutic targets for cancer metastasis Contains contributions from leading researchers around the globe
Download or read book Atlas of Clinical Cases on Brain Tumor Imaging written by Yelda Özsunar and published by Springer Nature. This book was released on 2020-04-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and analyzes clinical cases of brain tumors and follows the classification provided by the WHO in 2016. After introductory chapters reviewing the international literature on the topic, the advances made in all imaging modalities (especially Magnetic Resonance and Computed Tomography) are examined.All radiological findings are supplemented with a wealth of images and brief explanations. The clinical information is given as part of the case discussion, as are the characteristics and differential diagnosis of the tumors. Radiologic-pathologic correlations round out the description of each clinical case.Intended as a quick and illustrative reference guide for radiology residents and medical students, this atlas represents the most up-to-date, practice-oriented reference book in the field of Brain Tumor Imaging.
Download or read book Metastatic Disease of the Nervous System written by David Schiff and published by Elsevier. This book was released on 2018-01-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology
