Download or read book IgG4 Related Sclerosing Cholangitis written by Terumi Kamisawa and published by Springer. This book was released on 2018-07-31 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

Download or read book Allergy Proceedings written by and published by . This book was released on 1988 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book American Journal of Rhinology written by and published by . This book was released on 1988 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book IgG4 Related Kidney Disease written by Takao Saito and published by Springer. This book was released on 2016-11-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Nature. This book was released on 2020-11-03 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.

Download or read book Chronic Autoimmune Epithelitis written by and published by BoD – Books on Demand. This book was released on 2019-09-11 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Foundational Papers in Oculoplastics written by Sathyadeepak Ramesh and published by Springer Nature. This book was released on 2022-01-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern oculofacial plastic surgery as a field is quite young, with the majority of the literature and leaders in the field developing since the 1950s. As such, the body of literature is quite small compared to other fields. Currently, there is no unified source where readers can learn about the core manuscripts that drive clinical decision-making and influence thought. This book gathers over 50 foundational studies in the oculoplastics field and provides commentary on each study. Discussion of each study includes the abstract, in-depth commentary on the strengths, limitations, and implications of each paper, and guidance for further reading on the topic with a brief review. A short remark by an author from the paper will provide additional color commentary on the inspirations and challenges involved in conceiving and conducting the study. Foundational Papers in Oculoplastics is relevant for anyone who is interested in oculoplastics (ophthalmologists, oncologists, plastic surgeons, etc.) and provides a nice overview of the field with interesting personal anecdotes from those who helped establish it.

Download or read book Proceedings of 8th European Immunology Conference 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 29-July 01, 2017 Madrid, Spain Key Topics : Clinical and Cellular Immunology, Inflammatory/Autoimmune Diseases, T-Cells and B-Cells, Cancer and Tumor Immunobiology, Vaccines and Vaccination, Immunotherapy, Neuro Immunology, Infectious Diseases and Immune System, Reproductive Immunology, Immunodeficiences, Costimmulatory pathways in multiple sclerosis, Autoimmunity and Therapathies, Diagnostic Immunology, Clinical Immunology, Microbial, Parasitic, and Fungal Immunology, Allergy and Therapathies, Technological Innovations in Immunology, Antigen Processing, Hematopoiesis and Immune System Development, Immune Response Regulation, Molecular Mechanisms, Innate Immune Responses, Transplantation Immunology, Viral Immunology, Immunoinformatics and Systems Immunology, Cellular Adhesion, Immunopathology, Mucosal and Regional Immunology,

Download or read book Proceedings of 2nd International Conference on Autoimmunity 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: November 06-07, 2017 Frankfurt, Germany Autoimmune Disease, Autoimmune Treatment, Cytokine and Current Research, Neurodisorders, Antibodies: Engineering & Therapeutics, Inherited Autoimmunity, Clinical Autoimmunity: Current & Future Research, HIV Drugs: Trigger of Autoimmunity, Malignancy: The great Autoimmune Diseases, Immunotherapy Research, Lupus, Immune System and Autoimmunity, Molecular Immunology, Pediatric Autoimmunity, Immunometabolism and Autoimmunity, Ocular Autoimmunity,

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Download or read book Finding a Path to Safety in Food Allergy written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-27 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.

Download or read book Clinical Immunology written by Nima Rezaei and published by Academic Press. This book was released on 2022-08-16 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology. - Provides essentials, updates clinical knowledge regarding immune system diseases, and cover different aspects of clinical immunology, from immunopathogenesis and etiology to diagnosis and treatment - Introduces the most advanced approaches and laboratory tests as well as their interpretation in the diagnosis of immune system disorders - Focuses on the practical use of clinical immunology, from bedside to bench and vice versa

Download or read book Cancer and IgE written by Manuel L. Penichet and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Erika Jensen-Jarolim and Manuel L. Penichet 1. 1 Background Infectious diseases, being the major burden in the history of mankind worldwide th until the beginning of the 20 century, were important triggers in the understanding of immunological mechanisms. In contrast to infectious diseases, reports of all- gies and cancers were less common, but increased tremendously within the last century. Based on the US mortality data of the National Center for Health Statistics, Centers for Disease Control and Prevention 2009, a recent report from the American Cancer Society indicated that the number of cancer deaths increased approximately from 100,000 to 550,000 per year between 1930 and 2006, paralleling the increase of the total population during this period. Leading causes of death from cancer are lung and bronchus cancer, in men prostate cancer, and in women breast c- cer [1, 2]. Normalization to population size shows that the cancer death rate for most malignancies has been generally stable, although the mortality rate of certain malignancies, such as lung and bronchus cancer, has increased over the last 50 years [1-3]. In allergy, the situation is less clear, because for the time period around the turn of th the 19 century, only imprecise information is available. However, within the last 30 years the incidences of allergies has doubled not only in industrial countries, but in developing countries as well [4].

Download or read book Handbook of Atopic Eczema written by Thomas Ruzicka and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 1988 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Onco Nephrology E Book written by Kevin W. Finkel and published by Elsevier Health Sciences. This book was released on 2019-07-02 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed. - Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy. - Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer. - Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment. - Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care. - Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects. - Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.