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Book Interface Engineering of Capacitive Micromachined Ultrasonic Transducers for Medical Applications

Download or read book Interface Engineering of Capacitive Micromachined Ultrasonic Transducers for Medical Applications written by Der-Song Lin and published by Stanford University. This book was released on 2011 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capacitive micromachined ultrasonic transducers (CMUTs), have been widely studied in academia and industry over the last decade. CMUTs provide many benefits over traditional piezoelectric transducers including improvement in performance through wide bandwidth, and ease of electronics integration, with the potential to batch fabricate very large 2D arrays with low-cost and high-yield. Though many aspects of CMUT technology have been studied over the years, packaging the CMUT into a fully practical system has not been thoroughly explored. Two important interfaces of packaging that this thesis explores are device encapsulation (the interface between CMUTs and patients) and full electronic integration of large scale 2D arrays (the interface between CMUTs and electronics). In the first part of the work, I investigate the requirements for the CMUT encapsulation. For medical usage, encapsulation is needed to electrically insulate the device, mechanically protect the device, and maintain transducer performance, especially the access of the ultrasound energy. While hermetic sealing can protect many other MEMS devices, CMUTs require mechanical interaction to a fluid, which makes fulfilling the previous criterion very challenging. The proposed solution is to use a viscoelastic material with the glass-transition-temperature lower than room temperature, such as Polydimethylsiloxane (PDMS), to preserve the CMUT static and dynamic performance. Experimental implementation of the encapsulated imaging CMUT arrays shows the device performance was maintained; 95 % of efficiency, 85% of the maximum output pressure, and 91% of the fractional bandwidth (FBW) can be preserved. A viscoelastic finite element model was also developed and shows the performance effects of the coating can be accurately predicted. Four designs, providing acoustic crosstalk suppression, flexible substrate, lens focusing, and blood flow monitoring using PDMS layer were also demonstrated. The second part of the work, presents contributions towards the electronic integration and packaging of large-area 2-D arrays. A very large 2D array is appealing for it can enable advanced novel imaging applications, such as a reconfigurable array, and a compression plate for breast cancer screening. With these goals in mind, I developed the first large-scale fully populated and integrated 2D CMUTs array with 32 by 192 elements. In this study, I demonstrate a flexible and reliable integration approach by successfully combining a simple UBM preparation technique and a CMUTs-interposer-ASICs sandwich design. The results show high shear strength of the UBM (26.5 g), 100% yield of the interconnections, and excellent CMUT resonance uniformity ([lowercase Sigma] = 0.02 MHz). As demonstrated, this allows for a large-scale assembly of a tile-able array by using an interposer. Interface engineering is crucial towards the development of CMUTs into a practical ultrasound system. With the advances in encapsulation technique with a viscoelastic polymer and the combination of the UBM technique to the TSV fabrication for electronics integration, a fully integrated CMUT system can be realized.

Book Interface Engineering of Capacitive Micromachined Ultrasonic Transducers for Medical Applications

Download or read book Interface Engineering of Capacitive Micromachined Ultrasonic Transducers for Medical Applications written by Der-Song Lin and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Capacitive micromachined ultrasonic transducers (CMUTs), have been widely studied in academia and industry over the last decade. CMUTs provide many benefits over traditional piezoelectric transducers including improvement in performance through wide bandwidth, and ease of electronics integration, with the potential to batch fabricate very large 2D arrays with low-cost and high-yield. Though many aspects of CMUT technology have been studied over the years, packaging the CMUT into a fully practical system has not been thoroughly explored. Two important interfaces of packaging that this thesis explores are device encapsulation (the interface between CMUTs and patients) and full electronic integration of large scale 2D arrays (the interface between CMUTs and electronics). In the first part of the work, I investigate the requirements for the CMUT encapsulation. For medical usage, encapsulation is needed to electrically insulate the device, mechanically protect the device, and maintain transducer performance, especially the access of the ultrasound energy. While hermetic sealing can protect many other MEMS devices, CMUTs require mechanical interaction to a fluid, which makes fulfilling the previous criterion very challenging. The proposed solution is to use a viscoelastic material with the glass-transition-temperature lower than room temperature, such as Polydimethylsiloxane (PDMS), to preserve the CMUT static and dynamic performance. Experimental implementation of the encapsulated imaging CMUT arrays shows the device performance was maintained; 95 % of efficiency, 85% of the maximum output pressure, and 91% of the fractional bandwidth (FBW) can be preserved. A viscoelastic finite element model was also developed and shows the performance effects of the coating can be accurately predicted. Four designs, providing acoustic crosstalk suppression, flexible substrate, lens focusing, and blood flow monitoring using PDMS layer were also demonstrated. The second part of the work, presents contributions towards the electronic integration and packaging of large-area 2-D arrays. A very large 2D array is appealing for it can enable advanced novel imaging applications, such as a reconfigurable array, and a compression plate for breast cancer screening. With these goals in mind, I developed the first large-scale fully populated and integrated 2D CMUTs array with 32 by 192 elements. In this study, I demonstrate a flexible and reliable integration approach by successfully combining a simple UBM preparation technique and a CMUTs-interposer-ASICs sandwich design. The results show high shear strength of the UBM (26.5 g), 100% yield of the interconnections, and excellent CMUT resonance uniformity ([lowercase Sigma] = 0.02 MHz). As demonstrated, this allows for a large-scale assembly of a tile-able array by using an interposer. Interface engineering is crucial towards the development of CMUTs into a practical ultrasound system. With the advances in encapsulation technique with a viscoelastic polymer and the combination of the UBM technique to the TSV fabrication for electronics integration, a fully integrated CMUT system can be realized.

Book Medical Imaging

    Book Details:
  • Author : Troy Farncombe
  • Publisher : CRC Press
  • Release : 2017-12-19
  • ISBN : 1466582634
  • Pages : 740 pages

Download or read book Medical Imaging written by Troy Farncombe and published by CRC Press. This book was released on 2017-12-19 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book has two intentions. First, it assembles the latest research in the field of medical imaging technology in one place. Detailed descriptions of current state-of-the-art medical imaging systems (comprised of x-ray CT, MRI, ultrasound, and nuclear medicine) and data processing techniques are discussed. Information is provided that will give interested engineers and scientists a solid foundation from which to build with additional resources. Secondly, it exposes the reader to myriad applications that medical imaging technology has enabled.

Book Ultrasonics

    Book Details:
  • Author : Dale Ensminger
  • Publisher : CRC Press
  • Release : 2024-02-21
  • ISBN : 1000994953
  • Pages : 904 pages

Download or read book Ultrasonics written by Dale Ensminger and published by CRC Press. This book was released on 2024-02-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated, revised, and restructured to reflect the latest advances in science and applications, the fourth edition of this best-selling industry and research reference covers the fundamental physical acoustics of ultrasonics and transducers, with a focus on piezoelectric and magnetostrictive modalities. It then discusses the full breadth of ultrasonics applications involving low power (sensing) and high power (processing) for research, industrial, and medical use. This book includes new content covering computer modeling used for acoustic and elastic wave phenomena, including scattering, mode conversion, transmission through layered media, Rayleigh and Lamb waves and flexural plates, modern horn design tools, Langevin transducers, and material characterization. There is more attention on process monitoring and advanced nondestructive testing and evaluation (NDT/NDE), including phased array ultrasound (PAUT), long-range inspection, using guided ultrasonic waves (GUW), internally rotary inspection systems (IRIS), time-of-flight diffraction (TOFD), and acoustic emission (AE). These methods are discussed and applied to both metals and nonmetals using illustrations in various industries, including now additionally for food and beverage products. The topics of defect sizing, capabilities, and limitations, including the probability of detection (POD), are introduced. Three chapters provide a new treatment of high-power ultrasonics, for both fluids and solids, and again, with examples of industrial engineering, food and beverage, pharmaceuticals, petrochemicals, and other process applications. Expanded coverage is given to medical and biological applications, covering diagnostics, therapy, and, at the highest powers, surgery. Key Features Provides an overview of fundamental analysis and transducer technologies needed to design and develop both measurement and processing systems Considers applications in material characterization and metrology Covers ultrasonic nondestructive testing and evaluation and high-power ultrasonics, which involves interactions that change the state of material Highlights medical and biomedical applications of ultrasound, focusing on the physical acoustics and the technology employed for diagnosis, therapy, surgery, and research This book is intended for both the undergraduate and graduate scientists and engineers, as well as the working professional, who seeks to understand the fundamentals together with a holistic treatment of the field of ultrasonics and its diversity of applications.

Book Micromachined Ultrasonic Transducers

Download or read book Micromachined Ultrasonic Transducers written by and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfabricated ultrasonic transducers have been generated which operate in both liquids and gases. Air coupled through transmission of aluminum was observed for the first time using a pair of 2.3 MHz transducers. The dynamic range of the transducers was 110 dB, and the received signal had an SNR of 30 dB. Air coupled through transmission of steel and glass has also been observed. A theoretical model for the transducers has been refined and agrees well with experimental results. A robust microfabrication process has been developed and was used to generate air transducers which resonate from 2 to 12 MHz, as well as immersion transducers that operate in water from 1 to 20 MHz with a 60 dB dynamic range. Optimized immersion and air transducers have been designed and a dynamic range above 110 dB is anticipated. This development effort finds applications in hydrophones, medical ultrasound, nondestructive evaluation, ranging, flow metering, and scanning tip force sensing and lithography.

Book Image guided Focused Ultrasound Therapy

Download or read book Image guided Focused Ultrasound Therapy written by Feng Wu and published by CRC Press. This book was released on 2024-07-31 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment

Book Micromachined Ultrasonic Transducers

Download or read book Micromachined Ultrasonic Transducers written by Butrus T. Khuri-Yakub and published by . This book was released on 2005-11-01 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to teach the design and construction of micromachined ultrasonic transducers, an area rapidly increasing in popularity, and contrast and compare these transducers to each other and to traditional piezoelectric transducers. Micromachined ultrasonic transducers are gaining wide acceptance because of the use of silicon micromachining for their manufacture. This also enables capabilities of these transducers that outperform piezoelectric transducers and enable configurations that are practically impossible otherwise. This book teaches the principles of operations of micromachined ultrasonic transducers. The theory of their operation and the technology of their manufacturing will be discussed and compared to that of traditional piezoelectric transducers. Specific to the field of ultrasonic transducers, Micromachined Ultrasonic Transducers is directed at the communities that use ultrasound in the frequency range of kHz to many MHz for use in airborne and immersion applications.

Book Diagnostic Ultrasound Imaging  Inside Out

Download or read book Diagnostic Ultrasound Imaging Inside Out written by Thomas L. Szabo and published by Academic Press. This book was released on 2013-12-05 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field. Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the future Suitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasound Covers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models

Book Endorobotics

Download or read book Endorobotics written by Luigi Manfredi and published by Academic Press. This book was released on 2022-01-04 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprises three parts. The first part provides the state-of-the-art of robots for endoscopy (endorobots), including devices already available in the market and those that are still at the R&D stage. The second part focusses on the engineering design; it includes the use of polymers for soft robotics, comparing their advantages and limitations with those of their more rigid counterparts. The third part includes the project management of a multidisciplinary team, the health cost of current technology, and how a cost-effective device can have a substantial impact on the market. It also includes information on data governance, ethical and legal frameworks, and all steps needed to make this new technology available. Focuses on a new design paradigm for endorobots applications Provides a unique collection of engineering, medical and management contributions for endorobotics design Describes endorobotics, starting from available devices in both clinical use and academia

Book Ultrasonic Transducers

Download or read book Ultrasonic Transducers written by K Nakamura and published by Elsevier. This book was released on 2012-08-23 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasonic transducers are key components in sensors for distance, flow and level measurement as well as in power, biomedical and other applications of ultrasound. Ultrasonic transducers reviews recent research in the design and application of this important technology. Part one provides an overview of materials and design of ultrasonic transducers. Piezoelectricity and basic configurations are explored in depth, along with electromagnetic acoustic transducers, and the use of ceramics, thin film and single crystals in ultrasonic transducers. Part two goes on to investigate modelling and characterisation, with performance modelling, electrical evaluation, laser Doppler vibrometry and optical visualisation all considered in detail. Applications of ultrasonic transducers are the focus of part three, beginning with a review of surface acoustic wave devices and air-borne ultrasound transducers, and going on to consider ultrasonic transducers for use at high temperature and in flaw detection systems, power, biomedical and micro-scale ultrasonics, therapeutic ultrasound devices, piezoelectric and fibre optic hydrophones, and ultrasonic motors are also described. With its distinguished editor and expert team of international contributors,Ultrasonic transducers is an authoritative review of key developments for engineers and materials scientists involved in this area of technology as well as in its applications in sectors as diverse as electronics, wireless communication and medical diagnostics. Reviews recent research in the design and application of ultrasonic transducers Provides an overview of the materials and design of ultrasonic transducers, with an in-depth exploration of piezoelectricity and basic configurations Investigates modelling and characterisation, applications of ultrasonic transducers, and ultrasonic transducers for use at high temperature and in flaw detection systems

Book Sensors and Microsystems

Download or read book Sensors and Microsystems written by G. Di Francia and published by Springer Nature. This book was released on 2020-02-21 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book showcases the state of the art in the field of sensors and microsystems, revealing the impressive potential of novel methodologies and technologies. It covers a broad range of aspects, including: bio-, physical and chemical sensors; actuators; micro- and nano-structured materials; mechanisms of interaction and signal transduction; polymers and biomaterials; sensor electronics and instrumentation; analytical microsystems, recognition systems and signal analysis; and sensor networks, as well as manufacturing technologies, environmental, food and biomedical applications. The book gathers a selection of papers presented at the 20th AISEM National Conference on Sensors and Microsystems, held in Naples, Italy in February 2019, the event brought together researchers, end users, technology teams and policy makers.

Book Electromechanical Systems in Microtechnology and Mechatronics

Download or read book Electromechanical Systems in Microtechnology and Mechatronics written by Arno Lenk and published by Springer Science & Business Media. This book was released on 2010-10-01 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electromechanical systems consisting of electrical, mechanical and acoustic subsystems are of special importance in various technical fields, e.g. precision device engineering, sensor and actuator technology, electroacoustics and medical engineering. Based on a circuit-oriented representation, providing readers with a descriptive engineering design method for these systems is the goal of this textbook. It offers an easy and fast introduction to mechanical, acoustic, fluid, thermal and hydraulic problems through the application of circuit-oriented basic knowledge. The network description methodology, presented in detail, is extended to finite network elements and combined with the finite element method (FEM): the combination of the advantages of both description methods results in novel approaches, especially in the higher frequency range. The book offers numerous current examples of both the design of sensors and actuators and that of direct coupled sensor-actuator systems. The appendix provides more extensive fundamentals for signal description, as well as a compilation of important material characteristics. The textbook is suitable both for graduate students and for engineers working in the fields of electrical engineering, information technology, mechatronics, microtechnology, and mechanical and medical engineering.

Book Handbook of Modern Sensors

Download or read book Handbook of Modern Sensors written by Jacob Fraden and published by Springer Science & Business Media. This book was released on 2006-04-29 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seven years have passed since the publication of the previous edition of this book. During that time, sensor technologies have made a remarkable leap forward. The sensitivity of the sensors became higher, the dimensions became smaller, the sel- tivity became better, and the prices became lower. What have not changed are the fundamental principles of the sensor design. They are still governed by the laws of Nature. Arguably one of the greatest geniuses who ever lived, Leonardo Da Vinci, had his own peculiar way of praying. He was saying, “Oh Lord, thanks for Thou do not violate your own laws. ” It is comforting indeed that the laws of Nature do not change as time goes by; it is just our appreciation of them that is being re?ned. Thus, this new edition examines the same good old laws of Nature that are employed in the designs of various sensors. This has not changed much since the previous edition. Yet, the sections that describe the practical designs are revised substantially. Recent ideas and developments have been added, and less important and nonessential designs were dropped. Probably the most dramatic recent progress in the sensor technologies relates to wide use of MEMS and MEOMS (micro-electro-mechanical systems and micro-electro-opto-mechanical systems). These are examined in this new edition with greater detail. This book is about devices commonly called sensors. The invention of a - croprocessor has brought highly sophisticated instruments into our everyday lives.

Book Estimation of Blood Velocities Using Ultrasound

Download or read book Estimation of Blood Velocities Using Ultrasound written by Jørgen Arendt Jensen and published by Cambridge University Press. This book was released on 1996-03-29 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear, extensively illustrated treatment of ultrasound systems used in estimating blood velocities.

Book Fundamentals and Applications of Ultrasonic Waves

Download or read book Fundamentals and Applications of Ultrasonic Waves written by J. David N. Cheeke and published by CRC Press. This book was released on 2017-12-19 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written at an intermediate level in a way that is easy to understand, Fundamentals and Applications of Ultrasonic Waves, Second Edition provides an up-to-date exposition of ultrasonics and some of its main applications. Designed specifically for newcomers to the field, this fully updated second edition emphasizes underlying physical concepts over mathematics. The first half covers the fundamentals of ultrasonic waves for isotropic media. Starting with bulk liquid and solid media, discussion extends to surface and plate effects, at which point the author introduces new modes such as Rayleigh and Lamb waves. This focus on only isotropic media simplifies the usually complex mathematics involved, enabling a clearer understanding of the underlying physics to avoid the complicated tensorial description characteristic of crystalline media. The second part of the book addresses a broad spectrum of industrial and research applications, including quartz crystal resonators, surface acoustic wave devices, MEMS and microacoustics, and acoustic sensors. It also provides a broad discussion on the use of ultrasonics for non-destructive evaluation. The author concentrates on the developing area of microacoustics, including exciting new work on the use of probe microscopy techniques in nanotechnology. Focusing on the physics of acoustic waves, as well as their propagation, technology, and applications, this book addresses viscoelasticity, as well as new concepts in acoustic microscopy. It updates coverage of ultrasonics in nature and developments in sonoluminescence, and it also compares new technologies, including use of atomic force acoustic microscopy and lasers. Highlighting both direct and indirect applications for readers working in neighboring disciplines, the author presents particularly important sections on the use of microacoustics and acoustic nanoprobes in next-generation devices and instruments.

Book Basic Physics of Ultrasonographic Imaging

Download or read book Basic Physics of Ultrasonographic Imaging written by N. M. Tole and published by World Health Organization. This book was released on 2005 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume on basic physics of ultrasonographic imaging procedures provides clear and concise information on the physics behind ultrasound examinations in diagnostic imaging. It attempts to present the subject from a simple approach that should make it possible for the target groups to comprehend the important concepts which form the physical basis of ultrasonic imaging. The main target group of this manual is radiological technologists and radiographers working with diagnostic ultrasound in developing countries. Clinicians and nurse practitioners may also find the simple presentation appealing. A conscious effort has been made to avoid detailed mathematical treatment of the subject. The emphasis is on simplicity.

Book Electromechanical Transducers and Wave Filters

Download or read book Electromechanical Transducers and Wave Filters written by Warren Perry Mason and published by . This book was released on 1942 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: