Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Download or read book Immune System Modulations in Cancer Treatment written by Kadriye Kƒ±zƒ±lbey and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer immunotherapy is based on the idea of overcoming the main problems in the traditional cancer treatments and enhancing the patient,Äôs long-term survival and quality of life. Immunotherapy methods aimed to influence the immune system, to detect and eradicate the tumors site and predict the potential results. Nowadays, nanomaterials-based immunotherapy approaches are gaining interest due to numerous advantages like their ability to target cells and tissues directly and reduce the off-target toxicity. Therefore, topics about immune system components, nanomaterials, their usage in immunotherapy and the benefits they provide will be discussed in this presented book chapter. Immunotherapy can be divided into two groups mainly; active and passive immunotherapy including their subtitles such as immune checkpoint inhibitors, adoptive immunotherapy, CAR-T therapies, vaccines, and monoclonal antibodies. Main classification and the methods will be evaluated. Furthermore, state-of-art nanocarriers based immunotherapy methods will be mentioned in detail. The terms of size, charge, material type and surface modifications of the nanoparticles will be reviewed to understand the interference of immune system and nanoparticles and their advantages/disadvantages in immunotherapy systems.
Download or read book Control of Neoplasia by Modulation of the Immune System written by Michael A. Chirigos and published by Raven Press (ID). This book was released on 1977 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrient Modulation of the Immune Response written by Susanna Cunningham-Rund and published by CRC Press. This book was released on 2020-08-26 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book demonstrates that nutrients play a direct role as co-factors and regulators of the immune system. The book also shows that modulating the immune response with nutrients can provide a fundamental approach to preventive medicine.;Containing nearly 2300 bibliographic citations as well as illustrative figures, tables, and micrographs, this book is designed to be of interest to clinical immunologists, immunology and vitamin researchers, nutrition specialists, paediatricians, neonatologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.
Download or read book Immune Modulating Agents written by Thomas F. Kresina and published by CRC Press. This book was released on 2020-10-28 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing the systemic immune response in the contexts of health, disease, and therapy, this unique resource-the only broadly based book of its kind available on the subject-offers comprehensive examinations of the pathways and agents that affect the human immune response and provides state-of-the-art presentations on practical methods of immune modulation. Focuses on the immune response and modulation in infectious diseases, such as HIV, hepatitis, and parasitic infections and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer, and autoimmunity! Written by over 50 international authorities representing distinguished institutions in nine countries, Immune Modulating Agents introduces basic immunoregulatory mechanisms as homeostasis details cytokines, cellular and humoral immune responses, and hematopoiesis describes neuroendocrine - immune system interactions and the role of psychological stress on immune competence delineates factors that influence disease susceptibility, including nutrition covers drug delivery systems, gene therapy, organ transplantation, arthritis treatment, and vaccination strategies shows how to design clinical trials using immune modulating agents and more!
Download or read book Modulation of Human Immune Parameters by Anticancer Therapies written by Ulrich Sack and published by Frontiers Media SA. This book was released on 2021-01-18 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modulation of the immune system by bacteria from evasion to therapy written by Marina De Bernard and published by Frontiers Media SA. This book was released on 2023-04-10 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Plasticity and the Microenvironment Implications for Immunity and Therapy Response written by Petranel T. Ferrao and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells can change and adapt, especially within the host environment; a phenomenon known as cancer plasticity. Several factors, including the immune system can influence, and be influenced by, cancer plasticity which in turn can impact upon patient responses to treatment. As such, we currently face several challenges for implementing combination therapies as effective cancer treatment strategies. We have compiled a topic with a number of articles that emphasize the various aspects of cancer plasticity, describing in particular the important role of the tumor microenvironment. As we embark on a new era of precision medicine with multi-modal therapies for improving patient outcomes, this topic highlights some relevant points for consideration that are pertinent to the incorporation and effective use of new treatments as part of cancer treatment regimens, including immune-modulating drugs.
Download or read book Immune Modulation Agents and Their Mechanisms written by Richard L. Fenichel and published by Marcel Dekker. This book was released on 1984 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in Cancer Immunotherapy written by Shuren Zhang and published by Springer. This book was released on 2016-05-30 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.
Download or read book Modulation of Host Immune Resistance in the Prevention Or Treatment of Induced Neoplasias written by Michael A. Chirigos and published by . This book was released on 1977 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Download or read book Cancer Immunology and Immunotherapy written by Mansoor M. Amiji and published by Elsevier. This book was released on 2021-08-27 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO
Download or read book Radiation Induced Immune Modulation in Prostate Cancer written by and published by . This book was released on 2008 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiotherapy is generally considered to be immunosuppressive, whereas we hypothesized that it modulates immune responses and has profound effects on the immune system rather than eliminating of lymphocytes. The goal of this study was to determine how radiation affects the presentation of prostate specific antigen (PSA), to investigate new potential mechanisms of altered immune function after radiation therapy, and to devise strategies to overcome radiation-induced immunosuppression in prostate cancer using treatment with IL-3 and/or GM-CSF. In addition, because of the high risk nature of the experiments and the high PSA expression levels in prostate cancer patients that might interfere with its efficacy, we developed a second model using survivin as an antigen, since it also is over-expressed in prostate and other cancers.
Download or read book Chemokines and Cancer written by Barrett Rollins and published by Springer Science & Business Media. This book was released on 1999 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of microscopy, pathologists have noted tumor infiltration by inflammatory cells and presumed that this represents the host's attempt to reject its tumor. Recent advances in the molecular biology of inflammation have revealed the signals involved in attracting inflammatory cells to tumors and, for the most part, these signals are mediated by chemokines and their receptors. Chemokines are low molecular weight proteins that attract and activate specific subsets of leukocytes to the exclusion of others.
Download or read book Cells of the Immune System written by Ota Fuchs and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.
Download or read book Cell Interaction written by Bhawana Singh and published by BoD – Books on Demand. This book was released on 2021-04-07 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses contemporary ideas on different molecular and immunological aspects of diseases. Different signaling mediators drive the production of messenger molecules that mediate their action, leading to the elicitation/suppression of immune responses. It provides a balanced approach to the study of different molecular phenomena that eventually drive infection outcomes and that can be manipulated for therapeutic benefits.
