Download or read book Hyperuricemic Syndromes Pathophysiology and Therapy written by C. Ronco and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis syndromes have been identified which affect patients with cancer, especially in the phase of cellular destruction after chemotherapy. The detection of these hyperuricemic syndromes, together with the improved understanding of urate handling by the kidney, have spurred new interest in the pathophysiology of hyperuricemic states, their clinical consequences and management. Moreover, the recent development of a recombinant form of urate oxidase transforming uric acid into allantoin (Rasburicase) has caused new interest in the pathophysiology of hyperuricemia and the potential applications of this new drug. The multidisciplinary approach of this book offers new insights into the metabolic syndromes in question by uniting authors from the fields of biochemistry, pharmacology, rheumatology, onco-hematology, and nephrology. The result is a compendium of the present knowledge in the field, which will also be very useful as a reference tool for professionals and students who want to expand their knowledge on this topic.
Download or read book Hyperuricemic Syndromes written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis syndromes have been identified which affect patients with cancer, especially in the phase of cellular destruction after chemotherapy. The detection of these hyperuricemic syndromes, together with the improved understanding of urate handling by the kidney, have spurred new interest in the pathophysiology of hyperuricemic states, their clinical consequences and management. Moreover, the recent development of a recombinant form of urate oxidase transforming uric acid into allantoin (Rasburicase) has caused new interest in the pathophysiology of hyperuricemia and the potential applications of this new drug. The multidisciplinary approach of this book offers new insights into the metabolic syndromes in question by uniting authors from the fields of biochemistry, pharmacology, rheumatology, onco-hematology, and nephrology. The result is a compendium of the present knowledge in the field, which will also be very useful as a reference tool for professionals and students who want to expand their knowledge on this topic.
Download or read book Drug Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Download or read book Self injurious Behavior written by Stephen R. Schroeder and published by Amer Psychological Assn. This book was released on 2002-01-01 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, interdisciplinary review of the research on etiology and treatment of this chronic condition for which there is no known apparent cure. With an estimated prevalence rate of 13 per cent. SIB occurs most frequently among persons who are retarded and autistic. In this volume, the field's leading researchers examine a new generation of models and theories with a level of specificity far beyond what was heretofore imagined possible. From the burgeoning area of research on functional assessment and the behavioural and biological antecedents of SIB, to the role of Lesch-Nyhan Syndrome and opioid peptides, the work of these foremost basic, applied, and behavioural researchers is sure to greatly enhance feloow researchers', teachers', and clinicians' understanding of this devastating condition.
Download or read book Cancer Nursing written by Connie Henke Yarbro and published by Jones & Bartlett Publishers. This book was released on 2010-04-21 with total page 1985 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition. A new and revised version of this best-selling reference! For over eighteen years, best-selling Cancer Nursing: Principles and Practice has provided oncology nurses with the latest information on new trends in the rapidly changing science of oncology. Now, in its Seventh Edition, Cancer Nursing has been completely revised and updated to reflect key new developments. New topics covered include targeted therapy, hypersensitivity reactions, mucositis, and family and caregiver issues. With 27 new chapters featuring insights from key authors, the Seventh Edition is a must-have resource for every oncology nurse.
Download or read book Gout written by David S. Newcombe and published by Springer Science & Business Media. This book was released on 2012-10-12 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gout: Basic Science and Clinical Practice is a thoroughly researched comprehensive text which covers all important aspects of gout, including its genetics, pathophysiology, diagnosis, and management. Gout is probably the most common rheumatic disease after osteoarthritis and is becoming more common with the prevalence of the metabolic syndrome in the US, and in many other countries. Only about 10% of patients with gout are treated by rheumatologists and this often leads to inadequate diagnosis and treatment in general medical practice. Written by an expert in the field this book is valuable reference for rheumatologists and others in the medical profession who are interested in understanding and managing this important disease.
Download or read book Avoiding the First Cause of Death written by Wulf Dröge and published by iUniverse. This book was released on 2009-05 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interventions that delay aging are expected to improve health. In the current US National Institute on Aging's Interventions Testing Program (ITP) the immunosuppressive drug rapamycin was found to increase the maximum life span in mice. These mice started receiving this treatment at an age corresponding to 60 years in humans. Rapamycin targets the same mechanism which was critically involved in the life span extension previously seen in certain mutants of worms flies and mice. The maximum life span was increased in some of these mutants by more than 250 percent, suggesting 1) that the maximum life span is limited by a common mechanism of death, and 2) that humans may possibly gain a few more decades beyond 120 years by interfering in this mechanism. As rapamycin has important adverse effects, this books looks into the underlying mechanisms and describes several natural interventions likely to decrease the rate of aging without using pharmacological drugs.
Download or read book Challenging the Limits of the Human Life Span written by Wulf Dröge and published by iUniverse. This book was released on 2010-07-21 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interventions that delay aging are expected to improve health. In the current US National Institute on Agings Interventions Testing Program (ITP) the immunosuppressive drug rapamycin was found to increase the maximum life span in mice. These mice started receiving this treatment at an age corresponding to 60 years in humans. Rapamycin targets the same mechanism which was critically involved in the life span extension previously seen in certain mutants of worms flies and mice. The maximum life span was increased in some of these mutants by more than 250 percent, suggesting 1) that the maximum life span is limited by a common mechanism of death, and 2) that humans may possibly gain a few more decades beyond 120 years by interfering in this mechanism. As rapamycin has important adverse effects, this books looks into the underlying mechanisms and describes several natural interventions likely to decrease the rate of aging without using pharmacological drugs
Download or read book The Heart in Rheumatic Autoimmune and Inflammatory Diseases written by Udi Nussinovitch and published by Academic Press. This book was released on 2017-02-10 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence” and “strengths of recommendations” for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
Download or read book Silva s Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Download or read book American Book Publishing Record written by and published by . This book was released on 2005 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oxford Textbook of Osteoarthritis and Crystal Arthropathy Third Edition written by Michael Doherty and published by Oxford University Press. This book was released on 2016-10-06 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or supportive. The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. This edition also now includes new sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning. Also highly illustrated, the textbook is a strong reference tool with summary boxes and key points at the end of chapters making it easy to find information quickly and help you deliver the optimum patient outcome. The textbook equips rheumatologists and musculoskeletal health professionals with the knowledge to provide best possible patient care.
Download or read book Multiple Myeloma written by Morie A. Gertz and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Download or read book Pathology of Bone and Joint Disorders Print and Online Bundle written by Edward F. McCarthy and published by Cambridge University Press. This book was released on 2014-11-20 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.
Download or read book Acute Care Oncology Nursing written by Cynthia C. Chernecky and published by Elsevier Health Sciences. This book was released on 2008-04-24 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the likely first responder in an emergency, you need quick access to essential information on the potential complications of many different cancer types and treatments. The new edition of this trusted resource provides up-to-date information on the pathophysiology, complications, risks, treatment approaches, prognosis, assessment findings, and nursing and medical interventions for a wide range of cancers. It also offers valuable information to help you fulfill your role as care coordinator and patient advocate, including client education guidelines, discharge procedures, and strategies for helping the client and family deal with the impact of the disease's progression. A consistent format throughout helps you quickly find the information you need, no matter what the topic. This indispensable reference is written and reviewed by both oncology and acute care nurses, ensuring accuracy, currency, and clinical relevance. Coverage of each cancer includes pathophysiologic mechanisms, epidemiology and etiology, risk profile, prognosis, professional assessment criteria (PAC), nursing care and treatment, evidence-based practice update, patient teaching, nursing diagnoses or DSM-IV, evaluation and desired outcomes, and discharge planning with follow-up care, where needed. The latest prognosis statistics give you a realistic picture of the survival possibilities for your patients so you can provide the most appropriate nursing care and patient education. Multiple-choice review questions with answers and rationales at the end of each chapter help reinforce your understanding of key concepts and prepare you for certification examinations. Special boxes highlight pediatric-specific care considerations for working with children. Six new chapters - Biliary and Pancreatic Obstruction, Depression and Cognitive Dysfunction, Dyspnea and Airway Obstruction, GI Obstruction, Heart Failure, and Spiritual Distress - keep you up to date with the latest advances in oncology nursing. Evidence-based rationales in the nursing interventions help you apply the latest research findings to actual practice. Each chapter includes a new section on pathophysiology to help you understand the physiologic processes associated with each oncologic complication.
Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.
Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
