Download or read book Horizons in Cancer Research Volume 58 written by Hiroto S. Watanabe and published by . This book was released on 2015 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Topics discussed include oral cancer cachexia; the immunological mechanisms of cachexia; research in gynecologic oncology today; advances in cellular understanding of muscle wasting in cachexia; and next generation sequencing developments in cancer research by bioinformatics approaches.
Download or read book Horizons in Cancer Research Volume 87 written by Hiroto S. Watanabe and published by . This book was released on 2024-07-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2011 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Horizons in Cancer Research Volume 85 written by Hiroto S. Watanabe and published by . This book was released on 2023-04-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the latest developments in cancer research.
Download or read book Horizons in Cancer Research written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2011-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes articles that presents research results across a broad spectrum. It presents the research in the field of cancer research, including vaccine control strategies; environmental tobacco smoke and cancer; subtypes of breast cancer; cancer stem cells; and, gastrointestinal stromal tumours.
Download or read book Horizons in Cancer Research written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Horizons in Cancer Research written by Edward P. Morrison and published by Nova Biomedical Books. This book was released on 2010-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Horizons in Cancer Research' presents original research results on the leading edge of cancer research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2016-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One summarizes what is currently known regarding the epigenetic regulation of osteosarcoma pathways and oncogenes, as well as clinical trials of drugs that exert epigenetic regulation. Chapter Two critically discusses the role of ECM-dependent signaling in osteosarcoma progression. Chapter Three illustrates the harmful effects of ultraviolet radiation exposure by focusing on photocarcinogenesis. Chapter Four examines the psychology of sunscreen use and outlines the key psychological factors associated with sunscreen use. Chapter Five reviews the cellular and molecular mechanism of Regulatory T cells (Tregs) and Transforming Growth Factor-β mediating cervical cancer development. Chapter Six examines the affect of the American cranberry extract on expression of insulin-like growth factor-I and insulin-like growth factor binding proteins in human prostate cancer cells in vitro. Chapter Seven discusses the design of synthetic peptides to specifically interfere the papillomavirus binding factor/14-3-3beta binding to restore papillomavirus binding factor apoptotic functions. Chapter Eight examines brain development using correlations between Diffusion Kurtosis and neurite orientation dispersion and density imaging (NODDI) in neonates and young children. Chapter Nine highlights the opportunities that are available to prevent the late effects related to stress and fears, emphasizing the importance of teaching patients resiliency and how to cope.
Download or read book Horizons in Cancer Research Volume 78 written by Hiroto S. Watanabe and published by . This book was released on 2020-11-04 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation begins by discussing the common pediatric brain tumors, their key oncogenic drivers and signaling pathways. An update on the clinical trials against druggable targets is also provided.An outline of the metabolizing pathways in cancer and the mode of action of aerobic glycolysis in cancer cells is presented, also highlighting the roles of nanotechnology in energy-based cancer therapies.The authors review recent studies that characterize the specific mechanisms involved in mediating -tocotrienol reversal of epithelial-to mesenchymal transition in malignant breast cancer cells.The cytotoxic effects of Mannich bases derived from kojic acid on A375 human malignant melanoma are discussed and MRC-5 human lung cell lines are investigated using a sulphorhodamine B assay.Additionally, the cytotoxic effects and mechanisms displayed by metformin are assessed, alone or in combination with other agents. A better understanding of metformin-induced metabolic changes could aid in the discovery of new drugs, enhancing the efficacy of current melanoma therapeutics.In closing, the authors explore the way in which physical activity and exercise are negatively correlated to most type of cancers, as exercise shares common underlying metabolic pathways with those of some bioactive food compounds, such as polyphenols.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2013-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original research results on the leading edge of cancer. Topics discussed include coping mechanisms in patients with head and neck cancer; hepatocellular carcinoma; chronic lymphocytic leukaemia; the pathobiology of B-lymphoproliferative disorders from MBL to CLL to SLL; molecular and cellular characterisation of chronic lymphocytic leukemia; pain as a consequence in patients with early stage breast cancer treated with intracavity brachytherapy accelerated partial breast irradiation (IBAPBI); the future of anti-tumour immunotherapy; coping with childhood cancer; and the current clinical utility of Everolimus in the treatment of renal cell carcinoma.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2021-07-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents seven chapters detailing recent progress in the field of cancer research. Chapter One explores the application of robotic surgery to radical cystectomy, highlighting patient selection, surgical approach, perioperative and oncologic outcomes as well as some areas of controversy in the literature. Chapter Two describes the principles of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedures with its potential risks for patients and staff. Chapter Three discusses findings related to ISG15 and protein ISGylation, and their association with interferon signaling in cancer. Chapter Four describes the potential for MCF-7 cells to curb or counteract breast cancer. Chapter Five discusses the potential of emerging technologies in breast conserving treatment. Chapter Six reviews the current literature surrounding the basis of employing the immune system for the treatment of the various non-melanoma skin cancers (NMSC), discusses approved immunotherapies for each type of NMSC as well as indications for use, and synthesizes ongoing investigational studies of immunomodulatory agents for these diseases. Finally, Chapter Seven discusses the use of gene therapy in management of squamous cell carcinoma.
Download or read book Horizons in Cancer Research Volume 80 written by Hiroto S. Watanabe and published by . This book was released on 2021-06-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents six chapters detailing recent progress in the field of cancer research. Chapter One discusses the current information available regarding chemotherapy-induced peripheral neuropathy, including definition, prevalence, pathophysiology at nerve fibers, risk factors, physiology of specific antineoplastic agents on the peripheral nervous system, signs and symptoms, diagnostic criteria, and treatment methods. Chapter Two aims to substantiate the value of tumor-associated circulating and tissue miRNAs for assessing both the aggressiveness of the malignant process course and the sensitivity to neoadjuvant polychemotherapy (NPCT) in breast cancer patients of various molecular subtypes. Chapter Three summarizes the current role of nuclear factor kappa B (NF-κB) in cell aging, its dual functions in the balance of proliferation and apoptosis pathways and the current knowledge of not only the physiological but also the pathophysiological missions of NF-κB and its potential role as a target of therapeutic intervention against breast cancer. Chapter Four deals with 5-aminolevulinic acid radiodynamic therapy for treatment of high-grade gliomas. Chapter Five presents a literature review to identify the possible role of sex hormone receptors in gender variation and sexual dimorphism in the genesis and progression of urothelial bladder cancer (UBC). Lastly, Chapter Six discusses the risk factors, diagnostic modalities, and outcomes of cholangiocarcinoma (CCA), the second most common primary hepatobiliary malignancy.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2020-03-28 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opening chapter of this compilation extensively reviews scientific literature analyzing new molecular targets, ongoing research and future perspectives in the management of gastroenteropancreatic neuroendocrine neoplasms, a rare group of pathologically and clinically heterogeneous tumors. The significance of PI3K pathway components in lung cancer progression are highlighted, as well as possible therapeutic targets that can be explored in an effort to control the disease. Following this, the authors assess the contributions of flavin-containing monooxygenases 3 along with cytochrome P450 enzymes in Bu metabolic pathways, and analyze their effects on Bu kinetics. The role of the pro-tumorigenic cytokines and the significance of dysregulated notch signaling in the progression of colonic inflammation and carcinogenic transformation is also discussed. The current concepts of nutritional oncology in head and neck cancer patients are revised through a systematic literature search. Significant malnutrition has been reported due to several factors, such as a reduced dietary intake due to dysphagia and odynophagia, or catabolic factors secreted by the head and neck tumors. Lastly, an overview of cervical cancer screening around the world is provided. In the United States, a combination of HPV-testing and cytology method, the HPV-test-alone, and cytology-alone are widely performed.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2017-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One provides a comprehensive discussion to address the potential benefits of myricetin on cancer, diabetes, and neurodegenerative disease. It also discusses the underlined mechanism involved in the biological action of myricetin. Chapter Two discusses the clinical significance of vasculogenic mimicry. Chapter Three studies bacterial toxins as a direct cause of cancer. Chapter Four examines the immunological aspect of stroma in ovarian cancer. Chapter Five focuses on immune checkpoint inhibitors in the treatment of solid tumors. Chapter Six provides a review of targeting non-coding mitochondrial RNAs in gynecological and urinary malignancies. Chapter Seven explores the NF-κB signaling pathway, and its targeting in human cancer treatment. Chapter Eight analyses the circadian rhythm and skin cancer prevention. The final section of this book is a short commentary on melanoma.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by Nova Science Publishers. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents original results on the leading edge of cancer research. Chapter One presents an overview of the opportunities and challenges that influence the participation of personalised approach of giving the right drug at the right dose to the right patient. Chapter Two examines malignant mesothelioma. Chapter Three reviews the role of heat-shock proteins and chaperonins in the pathogenesis and progression of cancer. Chapter Four discusses the biosynthesis of LeX family glycosphingolipids and its gene regulation. Chapter Five summarises how chromosome segregation is accurately controlled and how spindle assembly checkpoint (SAC) monitors this process to maintain segregation fidelity. Chapter Six reviews significant novel findings and the early clinical development of a CD26-targeted therapy for malignant pleural mesothelioma (MPM), and advances that can lead to a more hopeful future for MPM patients. Chapter Seven reviews the pathophysiology and novel treatment strategies in management of peripheral T-Cell lymphoma. Chapter Eight discusses the confirmation behind a role for metformin in cancer therapy and its prospective molecular mechanisms of action. Chapter Nine highlights the role Ganoderma lucidum and its constituents in cancer signaling. Chapter Ten studies the footprint of Ganoderma lucidum in receptor tyrosine kinases.
Download or read book Horizons in Cancer Research written by Hiroto S. Watanabe and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
