Download or read book Histones and Other Basic Nuclear Proteins written by Gary S. Stein and published by CRC Press. This book was released on 1989-06-30 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book is a compilation of Professor Lubomir S. Hnilica's twenty years of research experimentally addressing the chemistry and the biological functions of chromosomal proteins. The histones and other nuclear proteins found associated with DNA in a number of tissues and cell types are featured. Lubomir Hnilica played a major role in establishing the extent to which these basic chromosomal polypeptides are conserved and the manner in which they interact with DNA to modify chromatin structure. In addition, non-histone chromosomal protein research is explained, and his technique of applying several biochemical and immunological approaches to the characterization of this complex and heterogeneous class of chromosomal polypeptides is discussed. Highlighted is the use of chemical crosslinking for studying protein/DNA interactions in intact cells. The proteins as well as the structure, organization, and regulation of the genes are also presented.
Download or read book Histones and Other Nuclear Proteins written by Harris Brusch and published by Elsevier. This book was released on 2012-12-02 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histones and Other Nuclear Proteins provides an introduction to the status of research and knowledge of histones and nuclear proteins. This book discusses the classification of the nuclear proteins, the role of proteins in control of the genome, repressor substances, and history of the nuclear proteins. Other topics include the primary structure of protamines, amino acid composition of histones, and direct isolation of nucleoproteins. The relationship of histones to chromosome structure, effects of histones on DNA synthesis, and sequential analysis of amino acids in the N-proline histone fraction is also deliberated. This text likewise covers the labeling of histones in vivo, physical and chemical properties of the acidic nuclear proteins, and enzymes involved in synthesis of nucleic acids. This publication is valuable to chemists and students aiming to acquire knowledge of histones and other nuclear proteins.
Download or read book Histones and Nucleohistones written by D. M. Philips and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: The histones are now a very well established part of Biochemistry. The interpretation of all that is known about them, however, is already too great a burden for a single author to undertake. Indeed, a survey of the indexed literature shows that the number of publications on the histones has approximately doubled in every three years for the past 15 years, and is now several hundred a year. It is time then to bring together in one publication the major topics embraced by this great research effort. This book therefore endeavours to give, in six chapters, a broad and searching account of the biochemistry and biophysics of these interesting proteins and their complexes with nucleic acids, the nucleohistones. Each chapter is written by different authors who are all active in this research and who have had many years experience with these proteins and their complexes. Chapters 1, 2, part of 3, and all of Chapters 5 and 6, cover the occurrence, preparation, characterization, sequence structure, bio physical properties and finally, the biosynthesis and functions of the histones. The other part of Chapter 3, the whole of Chapter 4 and to a less extent some other chapters, all discuss the properties and structure of the nucleohistones. The study of these complexes is undoubtedly of great importance in bridging the gaps in our knowledge of template activity and differentiation as well as of chromosomal structure and mechanics.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Biological Functions of Histones written by L.S. Hnilica and published by CRC Press. This book was released on 2018-05-04 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will contribute to a more general understanding of histone biochemistry and will provide stimulation, as well as source references, to the student of the cell nucleus and its functions.
Download or read book The Structure and Biological Functions of Histones written by Lubomir S. Hnilica and published by . This book was released on 1972 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will contribute to a more general understanding of histone biochemistry and will provide stimulation, as well as source references, to the student of the cell nucleus and its functions.
Download or read book The Structure and Function of Chromatin written by David W. FitzSimons and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Download or read book Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins written by Christoph Scholtissek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of nucleic acids has grown to such a tremendeous size that it is impossible to include all publications concerning the chemistry and biological role of nucleic acids in an article of the length presented in this "Volume. Therefore, it is necessary to select the most important contributions and those not included "in well-known reviews. In many cases reference is made only to the authors who summarized their specialized field in chapters of the three volumes of "The Nucleic Acids" (edB. E. CHARGAFF and J. N. DAVIDSON, Acad. Press, New York 1955 and 19(0) or to the "Nucleic Acid Outlines" (V. R. POTTER, Burgess Publishing Comp. Minneapolis), where further literature and more detailed discussions may be found. Facts and theories will be dealt with, but not lists of references. Therefore it is not possible to follow in all cases the historical development of an idea and to admowledge all publications which might be important and inter esting from another point of view. Very little is mentioned about methods in the field of nucleic acids.
Download or read book Chromosomal Proteins And Their Role In The Regulation Of Gene Expression written by Gary Stein and published by Elsevier. This book was released on 2012-12-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosomal Proteins and Their Role in the Regulation of Gene Expression examines how chromosomal proteins take part in the regulation of gene expression. This book also looks at the variety of approaches that are used in studying the structural and functional properties of chromosomal proteins, particularly as they relate to the control of transcription. This text is organized into 15 chapters and begins by analyzing the regulation of histone gene expression during the cell cycle and the role of non-histone chromosomal proteins in such regulation. The following chapters focus on the in vitro transcription of the globin gene in mouse fetal liver chromatin; the involvement of non-histone proteins in both positive and negative controls of gene activity; and the role of phosphorylated proteins as regulators of gene activity. The discussion then shifts to the phosphorylation state of non-histone proteins and its correlation with gene transcription; changes in nuclear proteins during embryonic development and cellular differentiation; and the manner by which histones are deposited onto replicating chromosomes. This book also explains the histone methylation, specific phosphorylation sites in lysine rich (H1) histone, and the separation and characterization of nuclear non-histone proteins by means of DNA columns. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in genetics, cell biology, molecular biology, biochemistry, and microbiology.
Download or read book Chromatin and Chromosomal Protein Research I written by and published by Academic Press. This book was released on 1977-08-24 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatin and Chromosomal Protein Research I
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.
Download or read book Mechanisms Underlying the Nuclear Transport of Histones and Histone related Proteins written by Jörg Kahle and published by . This book was released on 2005 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosomal Proteins and Gene Expression written by Gerald R. Reeck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book stems from an Advanced Study Institute on Chromo somal Proteins and Gene Expression that was held in Sitges, Spain, on September 17-26, 1984. It would be misleading to call this volume a conference proceedings, however. The ASI was not a conference, but a course with diverse activities, only one of which was a set of major presentations by the lecturers. Indeed, the concept of lecturer was intentionally obscured as we all learned from each other through shorter presentations by other participants and through seminars, poster sessions, and small group discussions. Furthermore, many participants found that exchanging ideas outside organized sessions was among the most rewarding aspects of the course. Some even claimed to have profitably probed the intricacies of nucleosome structure and transcriptional regulation while basking in the sun on the beachl Obviously, it is difficult to catch the flavor of such varied proceedings in a book. (I cannot confirm the incident on the beach, never having found time to set foot there. Such is the fate of the director of a meeting. ) The ASI was judged a success -- and enthusiastically so - by most participants. Not only did we deepen our understanding of our scientific field, we made new friends and learned about scientific and nonscientific aspects of life in other countries and about issues that transcend international boundaries in our complex world. We hope that this volume will be as successful as the course was.
Download or read book Histone Genes written by Gary S. Stein and published by Wiley-Interscience. This book was released on 1984 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fundamentals of Chromatin written by Jerry L. Workman and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.
Download or read book Total Chemical Synthesis of Proteins written by Ashraf Brik and published by John Wiley & Sons. This book was released on 2021-06-08 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.
