Download or read book Guidebook to the Small GTPases written by Huber Zerial and published by Sambrook and Tooze Publication at Oxford University Press. This book was released on 1995 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of their functional divergence the small GTPases proteins have been studied by researchers in the fields of structural biology, cell biology, cell growth and differentiation and developmental biology. This new Guidebook presents entries on almost 150 GTPases so far identified in aneasy to consult format. It will serve us an essential reference tool to all research workers with an interest in G-proteins.

Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field

Download or read book GTPases in Biology I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer. 80 chapters contain much previously unpublished data and, at the rate the extended family of GTPases is growing, it is unlikely that it will again sit for a group portrait such as this. Thus, this could well become the standard reference work.

Download or read book Handbook of H ATPases written by Suguru Nakamura and published by CRC Press. This book was released on 2014-03-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly

Download or read book Handbook of ATPases written by Masamitsu Futai and published by John Wiley & Sons. This book was released on 2006-01-24 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: ATP-dependent active ion transport enables cells to regulate their pH value and to control their ion composition. The reverse process, transforming an ion imbalance into chemical energy, drives mitochondrial and chloroplast ATP synthesis. The mediators of these fundamental processes are ion-motive ATPases, highly conserved enzymes that play key roles in cell physiology from bacteria to man. As the first comprehensive overview of this important class of enzymes, this handbook summarizes recent knowledge about the molecular mechanism of ATPases, relating this information to the physiology and pathopyhsiology of ion transport, mitochondrial function, vesicle transport and lysosomal acidification. All important P-type, F-type and V-type ATPases are treated systematically, complemented by a special section on the cell biology and physiology of acidic compartments, and backed by an extensive bibliography and index. This premier reference source for physiologists, molecular biologists, biophysicists and clinical researchers contains contributions by the world's foremost ATPase research groups.

Download or read book G Protein Coupled Receptor Guidebook written by Amy Sojka MS and published by Lulu.com. This book was released on 2015-07-20 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein-Coupled Receptors (GPCRs) represent a versatile family of plasma membrane receptors that elicit downstream intracellular signaling events. GPCRs play central roles in many physiological processes from sensory to neurological, cardiovascular, endocrine, and reproductive functions. Moreover GPCRs represent one of the largest gene families in the human genome, encoding approximately 800 unique proteins (Pawson et al., 2014). GPCRs' unique structure and cell surface location make them ideal "druggable" targets for different drug therapies, assuring interest in the pharmaceutical and clinical medicine communities (Vischer, Watts, Nijmeijer, & Leurs, 2011). It is estimated that roughly 40%% of pharmaceuticals currently marketed target GPCRs (Vischer et al., 2011). It is important for medical illustrators to know how to illustrate GPCRs and understand the scientific literature available.

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Maarten E.A. Reith and published by Springer Science & Business Media. This book was released on 2007-06-12 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The G Protein Coupled Receptors Handbook written by Lakshmi A. Devi and published by Springer Science & Business Media. This book was released on 2008-03-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

Download or read book The Oncogenomics Handbook written by William J. LaRochelle and published by Springer Science & Business Media. This book was released on 2007-11-09 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including Ritux an, Erbitux, Gleevec Herceptin, Avastin, ABX-EGF, Velcade, Kepivance, Iressa, Tarceva, and Zevalin are addressed. Highlights include cancer genomics, pharmacogenomics, transcriptomics, gene expression analysis, proteomic and enzymatic cancer profiling technologies, and cellular and animal approaches to cancer target validation.

Download or read book Handbook of Stress and the Brain Part 1 The Neurobiology of Stress written by Thomas Steckler and published by Elsevier. This book was released on 2005-02-25 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research* Includes timely discussion of stress and its effect on the immune system* Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms

Download or read book Handbook on Clostridia written by Peter Duerre and published by CRC Press. This book was released on 2005-03-29 with total page 1571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite growing scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments remains scattered in a variety of research ar

Download or read book Handbook of Neuroscience for the Behavioral Sciences Volume 1 written by Gary G. Berntson and published by John Wiley & Sons. This book was released on 2009-10-12 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: As technology has made imaging of the brain noninvasive and inexpensive, nearly every psychologist in every subfield is using pictures of the brain to show biological connections to feelings and behavior. Handbook of Neuroscience for the Behavioral Sciences, Volume I provides psychologists and other behavioral scientists with a solid foundation in the increasingly critical field of neuroscience. Current and accessible, this volume provides the information they need to understand the new biological bases, research tools, and implications of brain and gene research as it relates to psychology.

Download or read book Murray and Nadel s Textbook of Respiratory Medicine E Book written by Robert J. Mason and published by Elsevier Health Sciences. This book was released on 2010-06-09 with total page 2457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Murray and Nadel’s Textbook of Respiratory Medicine has long been the definitive and comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements. The fully searchable text is also online at www.expertconsult.com, along with regular updates, video clips, additional images, and self-assessment questions. This new edition has been completely updated and remains the essential tool you need to care for patients with pulmonary disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Master the scientific principles of respiratory medicine and its clinical applications. Work through differential diagnosis using detailed explanations of each disease entity. Learn new subjects in Pulmonary Medicine including Genetics, Ultrasound, and other key topics. Grasp the Key Points in each chapter. Search the full text online at expertconsult.com, along with downloadable images, regular updates, more than 50 videos, case studies, and self-assessment questions. Consult new chapters covering Ultrasound, Innate Immunity, Adaptive Immunity, Deposition and Clearance, Ventilator-Associated Pneumonia. Find critical information easily using the new full-color design that enhances teaching points and highlights challenging concepts. Apply the expertise and fresh ideas of three new editors—Drs. Thomas R. Martin, Talmadge E. King, Jr., and Dean E. Schraufnagel. Review the latest developments in genetics with advice on how the data will affect patient care.

Download or read book Cell Biology of Plant and Fungal Tip Growth written by Anja Geitmann and published by IOS Press. This book was released on 2001 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tip growth is a type of cellular growth that is represented in many and diverse cell types, which are important to plant breeding (pollen tubes), agriculture (root hairs) and plant and animal pathology (fungal hyphae). Also moss and fern protonemata as well as algal zygotes and yeasts exhibit the features unique for tip growth: directable apical linear growth which renders the cell able to penetrate its growth environment. In this volume various cell biological aspects of this particular growth phenomenon are discussed, such as the initiation and maintenance of an anisotropically growing cell, the function of cytoskeletal elements, extracellular matrix and turgor, the regulation of ion homeostasis, the mechanism of signalling events, and the interaction of the cell with the environment.

Download or read book Mechanobiology Handbook written by Jiro Nagatomi and published by CRC Press. This book was released on 2011-03-15 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology-the study of the effects of mechanical environments on the biological processes of cells-has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanob

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2008-06-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is highly fragile, especially during aging, illness and trauma. This book addresses a small sampling of major constituents of neural function at the cellular and molecular level that play crucial roles in development and aging.

Download or read book Handbook of Metallonutraceuticals written by Yashwant Vishnupant Pathak and published by CRC Press. This book was released on 2014-04-28 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nutritional and medicinal value of metals, such as zinc, calcium, and iron, has been known in traditional medicine for a long time. Other metals, such as silver and gold, may also have therapeutic and health benefits. Ancient medicines have long incorporated their use in the treatment of diseases, and they have also more recently been explored