Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Download or read book GnRH Analogues in Prostatic Cancer written by D. Jocham and published by S. Karger AG (Switzerland). This book was released on 1996-01-01 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of patients with metastatic carcinoma of the prostate poses a great challenge to urologists. Androgen ablation is still the basic therapy for advanced disease and can be achieved either surgically or chemically. In this setting GnRH agonists such as leuprorelin play an increasingly important role. One of the problems of androgen ablation is hormonal resistance, often occurring after 18-23 months, which necessitates second-line treatment of tumors. This publication discusses both current therapeutic issues and the urgent need for new, effective strategies to counteract this situation. Quality-of-life issues and the importance of epidemiological information are also given due consideration. This valuable exchange of information by experts in the field will be of interest to all clinicians and researchers concerned with advanced prostatic carcinoma.
Download or read book Goserelin Or Other Gonadotrophin Releasing Hormone GnRH Analogues in the Treatment of Advanced Prostate Cancer written by Wessex Institute for Health Research and Development and published by . This book was released on 1996 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fertility Preservation in Male Cancer Patients written by John P. Mulhall and published by Cambridge University Press. This book was released on 2013-02-21 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by international authorities, this book is aimed at clinicians dealing with male patients rendered infertile by cancer therapy.
Download or read book Drug Induced Liver Disease written by Neil Kaplowitz and published by CRC Press. This book was released on 2002-10-16 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
Download or read book Integration of Pharmaceutical Discovery and Development written by Ronald T. Borchardt and published by Springer Science & Business Media. This book was released on 2006-01-19 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.
Download or read book The Hypothalamus written by Seymour Reichlin and published by . This book was released on 1978 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fast Facts Prostate Cancer written by Roger S. Kirby and published by Karger Medical and Scientific Publishers. This book was released on 2017-03-08 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is unusual among solid tumors in that the majority of affected men die with, rather than of, the disease. This presents many challenges to healthcare professionals and patients in terms of deciding if, when and how to intervene in order to control tumor growth and spread, thereby extending survival but without compromising quality of life. This is the ninth edition of 'Fast Facts: Prostate Cancer' since 1996, testament to the rapid changes in the field and the steadily improving outlook for patients. This new edition provides many key updates: • the Gleason grade grouping, which has valuable prognostic value • nomograms to evaluate risk • our rapidly expanding understanding of the genetics and underlying pathogenesis of prostate cancer and the development of genomic tests to help identify those at greatest risk of developing clinically significant disease • the continuing debate about the role of PSA in the screening, detection and monitoring of prostate cancer • advances in imaging techniques, particularly multiparametric MRI, which is improving the accuracy of biopsy and reducing the numbers of negative biopsies • the roles of drugs, surgery and radiotherapy in the treatment of prostate cancer at different stages, and our ever-improving understanding of when and how best to intervene, aided by improving understanding of the risk factors for disease progression. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of prostate cancer, enabling fully informed discussions with patients about this complex disease. Contents: • Epidemiology and pathophysiology • Diet, lifestyle and chemoprevention • Screening and early detection • Diagnosis, staging and prognostic indicators • Management of clinically localized disease • Managing recurrence after initial therapy • Management of metastatic prostate cancer • Management of castrate-resistant prostate cancer • Survivorship and treatment complications
Download or read book GnRH Analogues and Prostate Cancer written by and published by . This book was released on 1999 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Absolute Clinical Radiation Oncology Review written by Daniel M. Trifiletti and published by Springer. This book was released on 2019-01-22 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and toxicity management. The subsequent chapters then delve into different cancer disease sites, including pediatrics, central nervous system, head and neck, thoracic, breast, gastrointestinal, gynecologic, genitourinary, hematologic, soft tissue, palliative, and radiophysics/radiobiology. Within each chapter, each disease and its recommended approach is then summarized in only a few pages, allowing a focus on the most essential information. Bullet points, figures, tables, and images make for an intuitive reader experience. Recommendations are taken from the American Society for Radiation Oncology (ASTRO), the European Society for Radiation Oncology (ESTRO), and the National Comprehensive Cancer Network (NCCN). Planning guides for imaging, diagnosis, and staging offer readers a starting point in approaching each patient based on disease origin, and dosing guidelines then detail consideration for treatment methods. Each chapter additionally includes disease-specific pearls and key points to test the knowledge reviewed in the chapters. Experts in the disease sites from the United States serve as senior authors on each chapter. The authors include all diseases associated with radiation oncology training to ensure a comprehensive resource for exam studying and clinical care. Residents, trainees, and established radiation oncologists find this an ideal study resource for both board and certification exams, as well as an easily accessible aid during practice.
Download or read book Advances in the Study of GnRH Analogues GnRH analogues and cancer plus a review of the treatment of uterine leiomyomata written by and published by . This book was released on 1992 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gynecologic and Urologic Pathology written by Maria Rosaria Raspollini and published by Cambridge University Press. This book was released on 2019-02-21 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.
Download or read book Hormone receptor Interaction written by Gerald S. Levey and published by . This book was released on 1976 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Textbook of Assisted Reproduction written by Gautam Nand Allahbadia and published by Springer Nature. This book was released on 2020-08-05 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples around the world. The book aims to cover all aspects of assisted reproduction. Particular attention is given to topics such as the assessment of infertile couples; assisted reproductive techniques (ARTs) including ovulation induction, intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (clinical and laboratory aspects); reproductive genetics; and obstetric and perinatal outcomes.
Download or read book Chemotherapy and Immunotherapy in Urologic Oncology written by Edouard J. Trabulsi and published by Springer Nature. This book was released on 2020-09-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.
Download or read book A Comparative Study on the Efficacies of Gonadotropin Releasing Hormone GnRH Agonist and GnRH Antagonist in Neoadjuvant Androgen Deprivation Therapy Combined with Transperineal Prostate Brachytherapy for Localized Prostate Cancer written by Asansol Asansol Press and published by . This book was released on 2016-11-22 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neoadjuvant androgen deprivation therapy (ADT) has been suggested to confer several clinical benefits in patients with prostate cancer (PCa) undergoing transperineal prostate brachytherapy (TPPB). Unlike gonadotropin-releasing hormone (GnRH) receptor agonists, a GnRH antagonist such as degarelix can achieve castrate levels of testosterone without testosterone flare. However, normalization of serum testosterone levels following completion of neoadjuvant ADT in either form of treatment has never been compared in clinical trials. Proceeds from the sale of this book go to support an elderly disabled person.
Download or read book 40th Annual Meeting of the American Society of Clinical Oncology written by American Society of Clinical Oncology. Annual Meeting and published by . This book was released on 2004 with total page 1140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
