Download or read book The Analysis of Gene Expression Data written by Giovanni Parmigiani and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.

Download or read book The Suffering Gene written by Roy Burdon and published by Zed Books. This book was released on 2003-05 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer kills one man out of every two, and one woman out of three, in the industrialized countries today. And its incidence, despite all efforts to the contrary, is increasing at one per cent a year. The fact is that some 80 per cent of cancers are likely to be due to environmental factors that could be reduced or even eradicated. This book explains how our genes work, and how they are adversely affected by the modern environment in which we live, whether in the North or the South. The factors include toxic industrial and agricultural chemicals, excessive sunlight ( a result of the hole in the ozone layer), nuclear radiation from power plants and the military, other forms of radiation (mobile phones, electricity transmission systems), food contaminants, atmospheric pollutants (tobacco smoke, car exhaust fumes), and the potential impact of genetic engineering. It explains how the body defends itself from external attack, what happens when these defences are overwhelmed, and the need for much more careful development of new technologies, industrial processes, products and foodstuffs.

Download or read book Bioinformatics written by Paul Dear and published by Scion Publishing Ltd. This book was released on 2007-09-24 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: INTRODUCTION (Paul H. Dear) 1. Database resources for wet-bench scientists (Neil Hall and Lynn Schriml) 2. Navigating sequenced genomes (Melody Clark and Thomas Schlitt) 3. Sequence similarity searches (Jaap Heringa and Walter Pirovano) 4. Gene prediction (Marie-Adele Rajandream) 5. Prediction of non coding transcripts (Alex Bateman and Sam Griffiths-Jones) 6. Finding regulatory elements in DNA sequence (Debraj GuhaThakurta and Gary Stormo) 7. Expressed sequence tags (Arthur Gruber) 8. Protein structure, classification and prediction (Arthur Lesk) 9. Gene ontology (Vineet Sangar) 10. Prediction of protein function (Rodrigo Lopez) 11. Multiple sequence alignment (Burkhard Morgenstern) 12. Inferring phylogenetic relationships from sequence data (Peter Foster) Appendix Index

Download or read book Vaccinia Virus and Poxvirology written by Stuart N. Isaacs and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner’s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now extinct or rare in nature (2). Recent genome sequencing studies confirm the distinctness of variola virus, cowpox virus, and vaccinia virus and also their very close genetic relationship, which accounts for the cross protection of smallpox vaccines. The novelty of the smallpox vaccine can be readily appreciated by the time it took, about 80 years, before the next live vaccine against rabies was developed, and another 50 years for the yellow fever vaccine. Moreover, the eradication of smallpox in 1977 stands as a unique medical achievement. Because of its historical role, sma- pox vaccination contributed greatly to present concepts of infectious disease, immunity, and pathogenesis. Less well known, however, are the many other “firsts” for vaccinia virus.

Download or read book Stem Cell Tools and Other Experimental Protocols written by and published by Elsevier. This book was released on 2006-12-12 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third of three planned volumes in the Methods in Enzymology series on the topic of stem cells. This volume is a unique anthology of stem cell techniques written by experts from the top laboratories in the world. The contributors not only have hands-on experience in the field but often have developed the original approaches that they share with great attention to detail. The chapters provide a brief review of each field followed by a “cookbook and handy illustrations. The collection of protocols includes the isolation and maintenance of stem cells from various species using “conventional and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell-specific techniques and approaches to tissue engineering using stem cell derivatives. The reader will find that some of the topics are covered by more than one group of authors and complement each other. Comprehensive step-by-step protocols and informative illustrations can be easily followed by even the least experienced researchers in the field, and allow the setup and troubleshooting of these state-of-the-art technologies in other laboratories. Provides complete coverage spanning from derivation/isolation of stem cells, and including differentiation protocols, characterization and maintenance of derivatives and tissue engineering Presents the latest most innovative technologies Addresses therapeutic relevance including FDA compliance and tissue engineering

Download or read book The Radish Genome written by Takeshi Nishio and published by Springer. This book was released on 2017-10-04 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the latest information and the status quo of radish genome studies to stimulate innovations and improvements in breeding techniques and to promote further advances in the field. Radish (Raphanus sativus) is a member of the Brassicaceae family and is cultivated worldwide. Its varieties have been diversified in terms of size, shape, and the color of their roots and bio-components. Thanks to the development of high-throughput molecular techniques using next generation sequencers, complete genomes of cultivated and wild radish plants have been sequenced and published with annotations of predicted genes and single nucleotide polymorphism (SNP) information between radish cultivars and accessions. These, together with the construction of a high-density genetic map of radish and profiling of expression sequences in radish organs, have accelerated genetic studies, such as the identification of genes or loci associated with root development, pungent components, and plant disease resistance. Providing an overview of these advances, this book is a valuable resource for scientists involved in plant genetic research and crop breeding.

Download or read book The Cooking Gene written by Michael W. Twitty and published by HarperCollins. This book was released on 2018-07-31 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2018 James Beard Foundation Book of the Year | 2018 James Beard Foundation Book Award Winner inWriting | Nominee for the 2018 Hurston/Wright Legacy Award in Nonfiction | #75 on The Root100 2018 A renowned culinary historian offers a fresh perspective on our most divisive cultural issue, race, in this illuminating memoir of Southern cuisine and food culture that traces his ancestry—both black and white—through food, from Africa to America and slavery to freedom. Southern food is integral to the American culinary tradition, yet the question of who "owns" it is one of the most provocative touch points in our ongoing struggles over race. In this unique memoir, culinary historian Michael W. Twitty takes readers to the white-hot center of this fight, tracing the roots of his own family and the charged politics surrounding the origins of soul food, barbecue, and all Southern cuisine. From the tobacco and rice farms of colonial times to plantation kitchens and backbreaking cotton fields, Twitty tells his family story through the foods that enabled his ancestors’ survival across three centuries. He sifts through stories, recipes, genetic tests, and historical documents, and travels from Civil War battlefields in Virginia to synagogues in Alabama to Black-owned organic farms in Georgia. As he takes us through his ancestral culinary history, Twitty suggests that healing may come from embracing the discomfort of the Southern past. Along the way, he reveals a truth that is more than skin deep—the power that food has to bring the kin of the enslaved and their former slaveholders to the table, where they can discover the real America together. Illustrations by Stephen Crotts

Download or read book Bioinformatics written by Hamid D. Ismail and published by CRC Press. This book was released on 2022-03-23 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics: A Practical Guide to NCBI Databases and Sequence Alignments provides the basics of bioinformatics and in-depth coverage of NCBI databases, sequence alignment, and NCBI Sequence Local Alignment Search Tool (BLAST). As bioinformatics has become essential for life sciences, the book has been written specifically to address the need of a large audience including undergraduates, graduates, researchers, healthcare professionals, and bioinformatics professors who need to use the NCBI databases, retrieve data from them, and use BLAST to find evolutionarily related sequences, sequence annotation, construction of phylogenetic tree, and the conservative domain of a protein, to name just a few. Technical details of alignment algorithms are explained with a minimum use of mathematical formulas and with graphical illustrations. Key Features Provides readers with the most-used bioinformatics knowledge of bioinformatics databases and alignments including both theory and application via illustrations and worked examples. Discusses the use of Windows Command Prompt, Linux shell, R, and Python for both Entrez databases and BLAST. The companion website contains tutorials, R and Python codes, instructor materials including slides, exercises, and problems for students. This is the ideal textbook for bioinformatics courses taken by students of life sciences and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

Download or read book Summary of Ben Lynch s Dirty Genes written by Everest Media, and published by Everest Media LLC. This book was released on 2022-03-25T22:59:00Z with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: Please note: This is a companion version & not the original book. Sample Book Insights: #1 Keri was already aware of what was making her sick: chemicals. She had figured out that she had at least one dirty gene, which was causing her to have a difficult time detoxing. #2 The MTHFR gene is crucial to the body’s most important biological process, methylation. As a result, a dirty MTHFR creates not only anxiety and depression, but a host of other symptoms, including weight gain, headache, fatigue, and brain fog. #3 Your genes are active participants in your daily health. They give instructions to your brain, digestive tract, skin, heart, liver, and many other aspects of your anatomy, and these instructions shape every facet of your experience and your health. #4 The way to get optimal health is by supporting your genes. I want you to give your first-line genes what they need to hand out the instructions for perfect health. I want your genes cooperating smoothly to give you glowing skin and a healthy weight and tons of energy and a clear, sharp mind.

Download or read book Nomenclature Avoiding Babylonian Speech Confusion in Present Day Immunology written by Menno C. van Zelm and published by Frontiers Media SA. This book was released on 2021-02-03 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). A/Prof. Menno van Zelm currently serves as the chairman for the IUIS Nomenclature Committee; Prof. Pablo Engel is the chair of the IUIS CD Nomenclature Sub-Committee; Prof. Loems Ziegler-Heitbrock is the chair of the IUIS Monocytes and Dendritic Cells in Blood Sub-Committee; Asst. Prof. Sanny Chan is a member of the WHO / IUIS Allergen Nomenclature Sub-Committee and A/Prof. Andrew Collins is co-chair of the Germline Gene Database (GLDB) Working Group of the Adaptive Immune Receptor Repertoire community (AIRR-C) and chair of the Inferred Allele Review Committee (IARC).

Download or read book Eating in the Dark written by Kathleen Hart and published by Vintage. This book was released on 2007-12-18 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most Americans eat genetically modified food on a daily basis, but few of us are aware we’re eating something that has been altered. Meanwhile, consumers abroad refuse to buy our engineered crops; their groceries are labeled so that everyone knows if the contents have been modified. What’s going on here? Why does the U.S. government treat engineered foods so differently from the rest of the world? Eating in the Dark tells the story of how these new foods quietly entered America’s food supply. Kathleen Hart explores biotechnology’s real potential to enhance nutrition and cut farmers’ expenses. She also reveals the process by which American government agencies decided not to label genetically modified food, and not to require biotech companies to perform even basic safety tests on their products. Combining a balanced perspective with a sense of urgency, Eating in the Dark is a captivating and important story account of the science and politics propelling the genetic alteration of our food.

Download or read book Functional Annotation of Farm Animal Genomes written by Hans Cheng and published by Frontiers Media SA. This book was released on 2021-12-20 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genes on the Menu written by Paul Pechan and published by Springer Science & Business Media. This book was released on 2005-01-17 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Only little more than a decade ago the term "genetic engineering" was hardly known outside research laboratories. Today it regularly makes headlines in the news. Supporters and opponents as well tell us that it could change our lives more than any other technological advance. This book delivers the state-of-the-art facts in order to empower the public to make knowledge-based decisions about plant biotechnology and GM crops and GM food, in particular. It discusses the hot topics of the present debate in a neutral manner and will function as a personal reference book for the interested public, for decision maker, and managers of consumer organisations.

Download or read book Genome Data Analysis written by Ju Han Kim and published by Springer. This book was released on 2019-04-30 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader’s bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases. The textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics.

Download or read book Super Genes written by Deepak Chopra, M.D. and published by Harmony. This book was released on 2015-11-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled. "You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting." Learning how to shape your gene activity is at the heart of this exciting and eagerly-anticipated book from the bestselling duo behind Super Brain, which became a nationwide hit on public television. For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago. The impact on prevention, immunity, diet, aging, and chronic disorders is unparalleled.

Download or read book Bioinformatics written by Andreas D. Baxevanis and published by John Wiley & Sons. This book was released on 2020-02-21 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the third edition of Bioinformatics "This book is a gem to read and use in practice." —Briefings in Bioinformatics "This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools." —ChemBioChem "A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly." —American Society for Microbiology News "This should be on the bookshelf of every molecular biologist." —The Quarterly Review of Biolog" The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today’s biologists are gaining fantastic new insights into the natural world’s most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with. The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards. This new edition features: New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics A thorough treatment of statistical methods as applied to biological data Special topic boxes and appendices highlighting experimental strategies and advanced concepts Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

Download or read book Plant Gene Regulatory Networks written by Kerstin Kaufmann and published by Springer Nature. This book was released on with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: