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Book Fitness Advantages Ans Disadvantages of Pyrethroid Resistance Mechanisms in the Yellow Fever Mosquito  Aedes Aegypti

Download or read book Fitness Advantages Ans Disadvantages of Pyrethroid Resistance Mechanisms in the Yellow Fever Mosquito Aedes Aegypti written by Leticia Barion Smith and published by . This book was released on 2019 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pyrethroid insecticides are commonly used to control Aedes aegypti, an important human disease vector; however, insecticide resistance is spreading rapidly amongst this mosquito species. Interactions between the two major mechanisms of pyrethroid resistance, cytochrome-P450-monooxygenases (CYPs)-mediated detoxification and voltage-sensitive sodium channel (Vssc) target gene modifications (known as kdr), can influence the rate that pyrethroid resistance evolves and therefore, influence the level of resistance in a population. Little is known about the evolution of the individual resistance mechanisms. Few studies have looked at how the interaction between the mechanisms affect resistance and none have compared how this interaction affects fitness. My goal was to study this interaction in two ways: how the mechanisms interact both in the presence of insecticides (i.e. their levels of resistance) and in the absence of insecticides (i.e. their fitness costs). I used three congenic strains containing the different resistance mechanisms alone and in combination: CYP:ROCK (CR) that contains only CYP-mediated detoxification; KDR:ROCK (KR) that contains only kdr; and CYP+KDR:ROCK (CKR) that contains both kdr and CYP-mediated resistance. I then assessed the resistance and cross-resistance of several pyrethroids and found that resistance varied by insecticide. In general, kdr confers greater resistance than CYPs and in combination, the resistance effect is greater-than-additive. Measuring fitness can be challenging because different types of experiments can resolve fitness costs differently, and synthesis of these results can be difficult. Here, I evaluated the fitness costs based on both specific fitness parameters (i.e. life table and mating competition), and by measuring overall fitness via an allele-competition study. Our life table results show a strong cost in the strains containing CYP-mediated resistance (CR and CKR), but not for kdr (KR). CKR males had a reduced mating success relative to ROCK males when attempting to mate with ROCK females. The allele-competition study results showed a significant decline in the kdr allele both in the presence and absence of CYP-mediated resistance, indicating a high cost for this allele. I found no correlation between the level of insecticide resistance conferred by the different mechanisms and their fitness cost. Understanding fitness costs is important for resistance management practices because it helps determine whether and how quickly resistance will be lost after pesticide application has ceased.

Book Biodiversity and Health in the Face of Climate Change

Download or read book Biodiversity and Health in the Face of Climate Change written by Melissa R. Marselle and published by Springer. This book was released on 2019-06-11 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book identifies and discusses biodiversity’s contribution to physical, mental and spiritual health and wellbeing. Furthermore, the book identifies the implications of this relationship for nature conservation, public health, landscape architecture and urban planning – and considers the opportunities of nature-based solutions for climate change adaptation. This transdisciplinary book will attract a wide audience interested in biodiversity, ecology, resource management, public health, psychology, urban planning, and landscape architecture. The emphasis is on multiple human health benefits from biodiversity - in particular with respect to the increasing challenge of climate change. This makes the book unique to other books that focus either on biodiversity and physical health or natural environments and mental wellbeing. The book is written as a definitive ‘go-to’ book for those who are new to the field of biodiversity and health.

Book Insecticides Resistance

Download or read book Insecticides Resistance written by Stanislav Trdan and published by BoD – Books on Demand. This book was released on 2016-03-02 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 20 chapters, which are divided into 5 sections. Section 1 covers different aspects of insecticide resistance of selected economically important plant insect pests, whereas section 2 includes chapters about the importance, development and insecticide resistance management in controlling malaria vectors. Section 3 is dedicated to some general questions in insecticide resistance, while the main topic of section 4 is biochemical approaches of insecticide resistance mechanisms. Section 5 covers ecologically acceptable approaches for overcoming insecticide resistance, such are the use of mycoinsecticides, and understanding the role of some plant chemical compounds, which are important in interactions between plants, their pests and biological control agents.

Book Vector Borne Diseases

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2008-03-18
  • ISBN : 0309177707
  • Pages : 350 pages

Download or read book Vector Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2008-03-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever, and plague, cause a significant fraction of the global infectious disease burden; indeed, nearly half of the world's population is infected with at least one type of vector-borne pathogen (CIESIN, 2007; WHO, 2004a). Vector-borne plant and animal diseases, including several newly recognized pathogens, reduce agricultural productivity and disrupt ecosystems throughout the world. These diseases profoundly restrict socioeconomic status and development in countries with the highest rates of infection, many of which are located in the tropics and subtropics. Although this workshop summary provides an account of the individual presentations, it also reflects an important aspect of the Forum philosophy. The workshop functions as a dialogue among representatives from different sectors and allows them to present their beliefs about which areas may merit further attention. These proceedings summarize only the statements of participants in the workshop and are not intended to be an exhaustive exploration of the subject matter or a representation of consensus evaluation. Vector-Borne Diseases : Understanding the Environmental, Human Health, and Ecological Connections, Workshop Summary (Forum on Microbial Threats) summarizes this workshop.

Book Genetically Modified Mosquitoes for Malaria Control

Download or read book Genetically Modified Mosquitoes for Malaria Control written by Christophe Boete and published by CRC Press. This book was released on 2006-07-15 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the epidemiological and evolutionary consequences of the use of genetically modified (GM) mosquitoes as well as research orientations and ethical issues concerning the use of GM mosquitoes. It also includes discussion on transgenic mosquitoes for malaria control.

Book Regulation of Agricultural Biotechnology  The United States and Canada

Download or read book Regulation of Agricultural Biotechnology The United States and Canada written by Chris A. Wozniak and published by Springer Science & Business Media. This book was released on 2012-08-29 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in a practical, didactic format designed to deliver point-of-care information to practitioners of cardiology as well as assist non-cardiologists with the efficient management of cardiac disease, this highly illustrated manual is an essential reference.

Book Dengue Fever

    Book Details:
  • Author : Jorge Abelardo Falcón-Lezama
  • Publisher : BoD – Books on Demand
  • Release : 2019-01-30
  • ISBN : 1789849993
  • Pages : 182 pages

Download or read book Dengue Fever written by Jorge Abelardo Falcón-Lezama and published by BoD – Books on Demand. This book was released on 2019-01-30 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 70 years, dengue fever has challenged health systems in every region of the World. It has evolved from a benign febrile illness from the tropics to a major concern in urban settlements, overwhelming health infrastructure with large outbreaks, as it continues to teach us important lessons with its complexities. This book intends to review the latest updates on dengue fever, the tools available for its study and control, and promising technologies currently in the pipeline. With this work, the editors wish to provide students with an updated reference text on the basics of this disease as well as researchers and academics, with a useful document to understand the current outlook and the perspectives for the future.

Book Fernald Club Yearbook

Download or read book Fernald Club Yearbook written by and published by . This book was released on 1995 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Aedes aegypti  the yellow fever mosquito

Download or read book Aedes aegypti the yellow fever mosquito written by Samuel Rickard Christophers and published by CUP Archive. This book was released on with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features information on Aedes aegypti, the yellow fever mosquito, presented by the Department of Bioagricultural Sciences and Pest Management at Colorado State University. Offers access to a genome database, anatomical drawings of Aedes aegypti, and maps.

Book Pyrethrum Flowers

    Book Details:
  • Author : John E. Casida
  • Publisher :
  • Release : 1994
  • ISBN : 9780195082104
  • Pages : pages

Download or read book Pyrethrum Flowers written by John E. Casida and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Dissertation Abstracts International

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2000 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Genetic Control of Malaria and Dengue

Download or read book Genetic Control of Malaria and Dengue written by Zach N. Adelman and published by Academic Press. This book was released on 2015-10-15 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission Provides a summary of the concepts of both population suppression and population replacement Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

Book Sterile Insect Technique

Download or read book Sterile Insect Technique written by Victor A. Dyck and published by CRC Press. This book was released on 2021-01-06 with total page 1493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sterile insect technique (SIT) is an environment-friendly method of pest control that integrates well into area-wide integrated pest management (AW-IPM) programmes. This book takes a generic, thematic, comprehensive, and global approach in describing the principles and practice of the SIT. The strengths and weaknesses, and successes and failures, of the SIT are evaluated openly and fairly from a scientific perspective. The SIT is applicable to some major pests of plant-, animal-, and human-health importance, and criteria are provided to guide in the selection of pests appropriate for the SIT. In the second edition, all aspects of the SIT have been updated and the content considerably expanded. A great variety of subjects is covered, from the history of the SIT to improved prospects for its future application. The major chapters discuss the principles and technical components of applying sterile insects. The four main strategic options in using the SIT — suppression, containment, prevention, and eradication — with examples of each option are described in detail. Other chapters deal with supportive technologies, economic, environmental, and management considerations, and the socio-economic impact of AW-IPM programmes that integrate the SIT. In addition, this second edition includes six new chapters covering the latest developments in the technology: managing pathogens in insect mass-rearing, using symbionts and modern molecular technologies in support of the SIT, applying post-factory nutritional, hormonal, and semiochemical treatments, applying the SIT to eradicate outbreaks of invasive pests, and using the SIT against mosquito vectors of disease. This book will be useful reading for students in animal-, human-, and plant-health courses. The in-depth reviews of all aspects of the SIT and its integration into AW-IPM programmes, complete with extensive lists of scientific references, will be of great value to researchers, teachers, animal-, human-, and plant-health practitioners, and policy makers.

Book Gene Drives on the Horizon

    Book Details:
  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release : 2016-08-28
  • ISBN : 0309437873
  • Pages : 231 pages

Download or read book Gene Drives on the Horizon written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

Book Communicable Disease Control in Emergencies

Download or read book Communicable Disease Control in Emergencies written by World Health Organization and published by World Health Organization. This book was released on 2005 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This field manual is intended to help health professionals and public health coordinators working in emergency situations prevent, detect and control the major communicable diseases encountered by affected populations. The manual is the result of collaboration among a number of WHO departments and several external partner agencies in reviewing existing guidelines on communicable disease control and adapting them to emergency situations. The manual deals with the fundamental principles of communicable disease control in emergencies, which are: Rapid assessment to identify the communicable disease threats faced by the emergency-affected population, including those with epidemic potential, and define the health status of the population by conducting a rapid assessment; Prevention to prevent communicable disease by maintaining a healthy physical environment and good general living conditions; Surveillance to set up or strengthen disease surveillance system with an early warning mechanism to ensure the early reporting of cases to monitor disease trends, and to facilitate prompt detection and response to outbreaks; outbreak control to ensure outbreaks are rapidly detected and controlled through adequate preparedness (i.e. stockpiles, standard treatment protocols and staff training) and rapid response (i.e.confirmation, investigation and implementation of control measures); and disease management to diagnose and treat cases promptly with trained staff using effective treatment and standard protocols at all health facilities.

Book Toolkit for Integrated Vector Management in Sub Saharan Africa  A

Download or read book Toolkit for Integrated Vector Management in Sub Saharan Africa A written by World Health Organization and published by World Health Organization. This book was released on 2016-07-27 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. It is an extension of earlier guidance and teaching material published by the World Health Organization (WHO): Handbook for integrated vector management Monitoring and evaluation indicators for integrated vector management Guidance on policy-making for integrated vector management and Core structure for training curricula on integrated vector management. The toolkit provides the technical detail required to plan implement monitor and evaluate an IVM approach. IVM can be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used presenting case studies on IVM as well as relevant guidance documents for reference. The diseases that are the focus of this toolkit are malaria lymphatic filariasis dengue leishmaniasis onchocerciasis human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever West Nile fever Chikungunya yellow fever) and trachoma. If other vector-borne diseases appear in a country or area vector control with an IVM approach should be adopted as per national priorities. Malaria as one of the most important vector-borne diseases in sub-Saharan Africa is the main focus of this document. Programmes targeting other vector-borne diseases can learn from the experiences gained from malaria vector control and presented here.