Download or read book Dynamic Plasma Membranes Portals Between Cells and Physiology written by and published by Academic Press. This book was released on 2016-01-09 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the recent advances in understanding plasma membrane organization and function beginning with simple systems and extending to specialized membrane domains of vertebrate cells. - Written by leading experts in the field - Contains original material, both textual and illustrative, that should become a very relevant reference material - Presents material in a very comprehensive manner - Ideal for both researchers in the field and general readers who will find relevant and up-to-date information

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dosage Form Design Considerations written by and published by Academic Press. This book was released on 2018-07-28 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Download or read book Coupling and Uncoupling Dynamic Control of Membrane Contacts written by Dan Zhang and published by Frontiers Media SA. This book was released on 2021-08-31 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Axon Neurobiology Fine Scale Dynamics of Microstructure and Function written by Haruyuki Kamiya and published by Frontiers Media SA. This book was released on 2020-12-09 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Organelle Contact Sites written by Mitsuo Tagaya and published by Springer. This book was released on 2017-08-16 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.

Download or read book Membrane Dynamics and Calcium Signaling written by Joachim Krebs and published by Springer. This book was released on 2018-03-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field. Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.

Download or read book Gap Junction Mediated Intercellular Signalling in Health and Disease written by Gail Cardew and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gap junctions are key elements in communication between cells in multicellular organisms. It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins that form the channels (connexins) are not yet fully understood. The last few years have seen considerable progress in this field and exciting new issues concerning gap junctional intercellular communication are being raised. Perturbed gap junction activity is beginning to be linked to certain pathologies, e.g. mutations in the major connexin of the heart have been found in human patients suffering from visceroatrial heterotaxia syndrome and mutations in the gene encoding another connexin have been found in patients with Charcot-Marie-Tooth disease. This book is the first to highlight the recent progress in understanding gap junction structure and to discuss the specific roles of individual connexins. It features contributions from an interdisciplinary group of experts who review the role of gap junctions in the heart, the retina and lens, the auditory system, the reproductive system, and in cell proliferation and cancer. The book will appeal to people interested in cell and molecular biology, embryonic development, neurobiology, cardiology, gynaecology and oncology.

Download or read book Golgi Dynamics in Physiological and Pathological Conditions written by Jaakko Saraste and published by Frontiers Media SA. This book was released on 2020-03-04 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cholesterol and PI 4 5 P2 in Vital Biological Functions written by Avia Rosenhouse- Dantsker and published by Springer Nature. This book was released on 2023-03-29 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholesterol is an essential component of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), although a minor phospholipid, is the most abundant membrane phosphoinositide. Both lipids play key roles in a variety of cellular functions including as signalling molecules and major regulators of protein function. Studies on these important lipids have traditionally focused on the effect of each lipid individually. Accumulating evidence indicates, however, that these lipids may cross-regulate each other’s levels. Furthermore, it is becoming evident that cholesterol and PI(4,5)P2 can act together to modulate protein function and biological processes. This book provides an overview of cellular functions and molecular mechanisms in which cholesterol and PI(4,5)P2 functions extend from parallel existence to crosstalk. It includes four sections. The first section introduces the reader to cholesterol and PI(4,5)P2. The second section demonstrates the mutual influence of these two critical lipids on their levels. The third section, divided into two parts, describes the co-modulation of protein function by cholesterol and PI(4,5)P2. The first part focuses on ion channels and the second - on lipid transfer proteins. The fourth section highlights other cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement. Collectively, the book portrays the emerging relationship between cholesterol and PI(4,5)P2 in a broad array of biological systems and processes. The book will be of interest to a wide audience of research scientists with an interest in the biophysical properties of lipids and the physiological consequences of their presence in biological systems, as well as graduate students, postdoctoral trainees, basic and clinical researchers, and pharmaceutical scientists. Specifically, the content will be relevant to researchers in the fields of biochemistry, molecular biophysics, pharmacology, neurobiology, cardiovascular biology, among others. Provides a comprehensive overview of the current knowledge of the interplay between cholesterol and PI(4,5) P2 Provides an overview of the emerging relationship between cholesterol and PI(4,5)P2 in biological systems and processes Discusses cellular processes and molecular mechanisms where lipid functions extend from parallel existence to crosstalk

Download or read book Bacterial Persistence written by Jan Michiels and published by Humana. This book was released on 2015-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in Escherichia coli cultures, protocols for the determination of the persister subpopulation in Candida albicans, quantitative measurements of Type I and Type II persisters using ScanLag, to in vitro and in vivo models for the study of the intracellular activity of antibiotics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Persistence: Methods and Protocols brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.

Download or read book Cell Membranes written by Lukas Buehler and published by Garland Science. This book was released on 2015-06-17 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Membranes offers a solid foundation for understanding the structure and function of biological membranes. The book explores the composition and dynamics of cell membranes discussing the molecular and biological diversity of its lipid and protein components and how the combinatorial richness of both components explains the chemical, mechanical,

Download or read book Lipids in Plant and Algae Development written by Yuki Nakamura and published by Springer. This book was released on 2016-03-29 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes recent advances in understanding the functions of plant and algal lipids in photosynthesis, in development and signaling, and in industrial applications. As readers will discover, biochemistry, enzymology and analytical chemistry, as well as gene knock-out studies have all contributed to our rapidly increasing understanding of the functions of lipids. In the past few decades, distinct physical and biochemical properties of specific lipid classes were revealed in plant and algal lipids and the functional aspects of lipids in modulating critical biological processes have been uncovered. These chapters from international authors across relevant research fields highlight the underlying evolutionary context of lipid function in photosynthetic unicellular and multicellular organisms. The book goes on to encompass what lipids can do for industrial applications at a time of fascination with plants and algae in carbon fixation and as sources for production of food, energy and novel chemicals. The developmental context is a part of the fresh and engaging perspective that is presented in this work which graduate students and scientists will find both illuminating and useful.

Download or read book Structure and Dynamics of Membranes written by R. Lipowsky and published by Elsevier. This book was released on 1995-06-15 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Download or read book Glycinergic transmission physiological developmental and pathological implications written by Robert J. Harvey and published by Frontiers E-books. This book was released on with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhibitory glycine receptors (GlyRs) containing the alpha1 and beta subunits are well known for their involvement in an inherited motor disorder (hyperekplexia) characterised by neonatal hypertonia and an exaggerated startle reflex. However, it has recently emerged that other GlyR subtypes (e.g. those containing the alpha2, alpha3 and alpha4 subunits) may play more diverse biological roles. New animal models of glycinergic dysfunction have been reported in zebrafish (bandoneon, shocked), mice (cincinatti, Nmf11) and cows (CMD2). In addition, key studies on neurotransmitter transporters for glycine (GlyT1, GlyT2, VIAAT) have also revealed key roles for these presynaptic and glial proteins in health and disease. Molecular modelling and structure/function studies have also provided key insights into allosteric signal transduction mechanisms and the diverse pharmacology of glycine receptors. This Research Topic aims to bring together experts in the field of glycinergic transmission, and invite research articles or topical reviews to provide an up-to-date perspective on the insights into receptor, transporter and synaptic function that can be gained by the study of glycinergic transmission.

Download or read book Membrane Receptors Dynamics and Energetics written by K. Wirtz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Physiology written by Ashis Banerjee and published by Cambridge University Press. This book was released on 2005-09-22 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an admirably concise and clear guide to fundamental concepts in physiology relevant to clinical practice. It covers all the body systems in an accessible style of presentation. Bulleted checklists and boxed information provide an easy overview and summary of the essentials. By concentrating on the core knowledge of physiology, it will serve as a useful revision aid for all doctors striving to achieve postgraduate qualification, and for anyone needing to refresh their knowledge base in the key elements of clinical physiology. The author's own experience as an examiner at all levels has been distilled here for the benefit of postgraduate trainees and medical and nursing students.