Download or read book Dopamine in the CNS I written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Download or read book Encyclopedia of Movement Disorders written by and published by Academic Press. This book was released on 2010-02-26 with total page 1633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists

Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.

Download or read book Dopamine Receptor Subtypes written by Peter Jenner and published by IOS Press. This book was released on 1998 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple subtypes of dopamine receptors exist in the brain. This volume reviews the characteristics of D-1, D-2, D-3 and D-4 receptors and describes the current concepts of their involvement in motor disorders and in the control of schizophrenia. Readers: the book will be of great interest to professionals in pharmacology, medicinal chemistry, neuroscience, cell biology and therapeutic applications in clinical medicine as antipsychotics, anti-Parkinson's disease and related areas.

Download or read book Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Download or read book The Dopamine Receptors written by Kim Neve and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and newcomers to the dopamine receptor field, while at the same time providing up-to-date summaries of the most active areas of research. It is difficult these days to write about receptors without addressing the issue of receptor nomenclature. For dopamine receptors, valid arguments can be made for a system in which the subtypes are classified as belonging to the Dl or D2 classes, with letters assigned in the order of cloning (D A, D , D A, 1 18 2 D , Dc). We decided, however, that common usage counts for something, and 28 2 chose to use D , D , and D for the D2-like receptors because these names are 2 3 4 nearly unanimously used in the literature.

Download or read book Medical Biochemistry written by N. V. Bhagavan and published by Academic Press. This book was released on 2002 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the fundamentals of biochemistry and related topics for all those pursuing medical or other health-related fields such as clinical chemistry, medical technology, or pharmacology.

Download or read book Anesthesiology Core Review written by Brian Freeman and published by McGraw Hill Professional. This book was released on 2014-07-06 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination.

Download or read book Fluorine and Health written by Alain Tressaud and published by Elsevier. This book was released on 2008-06-06 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics

Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.

Download or read book Receptor Receptor Interactions written by Kjell Fuxe and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book First Episode Psychosis written by Katherine J. Aitchison and published by CRC Press. This book was released on 1999-02-17 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.

Download or read book Primer on the Autonomic Nervous System written by Phillip A. Low and published by Elsevier. This book was released on 2004-06-02 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientist's bookshelf! - Greatly amplified and updated from previous edition including the latest developments in the field of autonomic cardiovascular regulation and neuroscience - Provides key information about all aspects of autonomic physiology and pathology - Discusses stress and how its effects on the body are mediated - Compiles contributions by over 140 experts on the autonomic nervous system

Download or read book Neuropsychiatric Disorders and Epigenetics written by Jacob Peedicayil and published by Elsevier. This book was released on 2023-09-29 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant to disease.This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy. By helping to define epigenetics as a key player in neuropsychiatric disorders, this volume empowers new research, clinical translation, and pharmacological advances, and highlights promising directions for ongoing investigation. - Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction - Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists - Features extensive use of diagrams, illustrations, tables, and graphical abstracts for each section to reinforce understanding - - Includes chapter contributions from leading global experts

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Download or read book Autonomic Neurology written by Eduardo E. Benarroch and published by Oxford University Press. This book was released on 2014-04-03 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.

Download or read book Presynaptic Receptors and Neuronal Transporters written by S.Z. Langer and published by Elsevier. This book was released on 2013-10-22 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.