Download or read book Determination of Some Carcinogenic Contaminants in Food written by Sergei Yurchenko and published by . This book was released on 2006 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Some Chemicals Present in Industrial and Consumer Products Food and Drinking water written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-03-12 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Download or read book Safety Evaluation of Certain Contaminants in Food written by Joint FAO/WHO Expert Committee on Food Additives. Meeting and published by Food & Agriculture Org.. This book was released on 2006 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diet Nutrition And Cancer written by National Research Council and published by Legare Street Press. This book was released on 2022-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Download or read book Food Contaminants and Residue Analysis written by Yolanda Picó and published by Elsevier. This book was released on 2008-09-10 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Contaminants and Residue Analysis treats different aspects of the analysis of contaminants and residues in food and highlights some current concerns facing this field. The content is initiated by an overview on food safety, the objectives and importance of determining contaminants and residues in food, and the problems and challenges associated to these analyses. This is followed by full details of relevant EU and USA regulations. Topics, such as conventional chromatographic methods, accommodating cleanup, and preparing substances for further instrumental analysis, are encompassed with new analytical techniques that have been developed, significantly, over the past few years, like solid phase microextraction, liquid chromatography-mass spectrometry, immunoassays, and biosensors. A wide range of toxic contaminants and residues, from pesticides to mycotoxins or dioxins are examined, including polychlorinated biphenyls, polycyclic aromatic hydrocarbons, N-nitrosamines, heterocyclic amines, acrylamide, semicarbazide, phthalates and food packing migrating substances. This book can be a practical resource that offers ideas on how to choose the most effective techniques for determining these compounds as well as on how to solve problems or to provide relevant information. Logically structured and with numerous examples, Food Contaminants and Residue Analysis will be valuable a reference and training guide for postgraduate students, as well as a practical tool for a wide range of experts: biologists, biochemists, microbiologists, food chemists, toxicologists, chemists, agronomists, hygienists, and everybody who needs to use the analytical techniques for evaluating food safety.
Download or read book Diet Nutrition and Cancer written by National Research Council (U.S.). Committee on Diet, Nutrition, and Cancer and published by . This book was released on 1982 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Safety evaluation of certain contaminants in food written by World Health Organization and published by World Health Organization. This book was released on 2023-07-14 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Food Chemical Risk Analysis written by David R. Tennant and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Chemical Risk Analysis provides an introduction to the sciences of food chemistry and risk analysis and demonstrates how the potential hazards associated with food chemicals can be assessed and managed. Food scares are never far from the news and particular attention is therefore focused on the consumer perception of risk and risk communication. Leading international experts provide unique insights in the future of food chemical risk analysis. Chapters on alternatives to animal testing show how emerging methods offer the prospect of a more rational human-based approach to toxicity testing. Discussions about relative risks and protective factors highlight the possibility that risks from food can be over-estimated and approaches to avoid such risks are proposed. The science of risk management is presented as more than just a method for translating science into policy by demonstrating how social, psychological, economic ethical and other factors can, and should be taken into account. The book makes it clear that if risk communication is to be effective, an integrated approach to risk analysis must be adopted.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Establishment of Analytical Methods for the Determination of New Foodprocessed Contaminants written by Mohammed-Soubhi Altaki and published by . This book was released on 2017 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of sensitive analytical methods has allowed identifying non- nutrient chemicals in food that may affect the human health and are recognised as food chemical contaminants. Some of these compounds are originated from food processing and several studies have demonstrated that can induce tumours in animals. Process- induced food carcinogens are defined as those undesirable chemicals unintentionally present in food as a result of processing and/or preparation of the raw material. The discovery of acrylamide in processed carbohydrate rich food in 2002 sparked renewed interest on some other known food carcinogens such as volatile N-nitrosamines (VNAs) and has also led to the discovery of some others that were previously unknown like furan. Furan and volatile N-nitrosamines (VNAs) are induced food toxicants and due to their potential harmful effects on human health, they have been classified as probable and/or possible carcinogens to humans by the International Agency for Research on Cancer (IARC). At present, food processing technologies able to prevent their formation are not available. To guarantee food safety, identification and quantification of food contaminants as well as the evaluation of their occurrence and risk assessment are needed. An indispensable prerequisite to fulfil these objectives is to have available reliable analytical methodologies. The analysis of furan and volatile N-nitrosamines is challenging due to their physicochemical properties, relatively low concentration levels and the complexity of the food matrices and therefore, there is interest to explore new analytical methodologies able to enhance sensitivity, selectivity, adaptability and also to meet the criteria of European Commission (2002/657/EC) regarding the validation and establishing the performance of analytical methods. In this context, this thesis was conducted to study furan and volatile N- nitrosamines as process-induced food toxicants from the development of analytical methodologies to the evaluation of their presence in food and risk assessment estimation for Spanish population. A fully automated headspace solid-phase microextraction (HS- SPME) gas chromatography coupled to ion-trap mass spectrometry (GC-ITMS) methods to evaluate the presence of these contaminants in food products and to estimate the real exposure of the population to these compounds were established. Parameters affecting the HS-SPME performance including extraction and desorption conditions were experimentally optimised in order to obtain the maximum extraction efficiencies. In addition, GC-ITMS methods using electron ionization and full scan MS mode for furan analysis and selected reaction monitoring tandem mass spectrometry with chemical ionization (CI-IT MS/MS) for VNAs analysis were developed. The experimental results are presented in three scientific papers, two devoted to furan determination and one to the analysis of volatile N-nitrosamines. The applicability of both HS-SPME-GC-MS methods for the determination of furan and VNAs has been demonstrated analysing several selected foods commercialised in Spain. Furan was detected in all samples at concentrations, being baby food and coffee the products with the highest furan content. In contrast, VNAs were not detected in any of the analysed beer samples at concentrations levels above limits of quantification, and the presence of VNAs (NDMA and NPYR) were only found in 3 out of 18 processed meat product samples analysed indicating the effectiveness of the measures adopted by the manufactures to avoid the formation of VNAs. Therefore, a survey on furan content in coffee brews and baby foods was conducted while this study was not performed for VNA because of the low frequency and levels found in the samples analysed in this thesis. The presence of furan in coffee and baby food categories constitutes a potential risk for human health because they contain high furan content and are highly consumed. The evaluation of furan levels found in these food products are included in two scientific articles. In addition, the effect food preparation, heating and handling, on furan content and an estimation of risk assessment of furan intake from food consumption are also included.
Download or read book Outdoor Air Pollution written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."
Download or read book Red Meat and Processed Meat written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by International Agency for Research on Cancer. This book was released on 2018-07-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the consumption of red meat and the consumption of processed meat. Red meat refers to unprocessed mammalian muscle meat (e.g. beef, veal, pork, lamb) including that which may be minced or frozen. Processed meat refers to meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavor or improve preservation. Most processed meats contain pork or beef, but may also contain other meats including poultry and offal (e.g. liver) or meat by-products such as blood. Red meat contains proteins of high biological value, and important micronutrients such as B vitamins, iron (both free iron and haem iron), and zinc. Carcinogens, including heterocyclic aromatic amines and polycyclic aromatic hydrocarbons, can be produced by cooking of meat, with greatest amounts generated at high temperatures by pan-frying, grilling, or barbecuing. Meat processing such as curing and smoking can result in formation of carcinogenic chemicals including N-nitroso compounds and polycyclic aromatic hydrocarbons. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of the consumption of red meat and processed meat. The Working Group assessed more than 800 epidemiological studies that investigated the association of cancer (more than 15 types) with consumption of red meat or processed meat, including large cohorts in many countries, from several continents, with diverse ethnicities and diets.
Download or read book Mycotoxins in Food written by N Magan and published by Elsevier. This book was released on 2004-07-16 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins, toxic compounds produced by fungi, pose a significant contamination risk in both animal feed and foods for human consumption. With its distinguished editors and international team of contributors, Mycotoxins in food summarises the wealth of recent research on how to assess the risks from mycotoxins, detect particular mycotoxins and control them at differing stages in the supply chain. Part one addresses risk assessment techniques, sampling methods, modelling and detection techniques used to measure the risk of mycotoxin contamination and the current regulations governing mycotoxin limits in food. Part two looks at how the risk of contamination may be controlled, with chapters on the use of HACCP systems and mycotoxin control at different stages in the supply chain. Two case studies demonstrate how these controls work for particular products. The final section details particular mycotoxins, from ochratoxin A and patulin to zearalenone and fumonisins. Mycotoxins in food is a standard reference for all those concerned with ensuring the safety of food. Discusses the wealth of recent research in this important area Covers risk assessment, detection of particular mycotoxins and how to control them throughout the supply chain Describes how the risk of contamination can be controlled, including the use of HACCP systems
Download or read book Acrylamide in Food written by Vural Gokmen and published by Academic Press. This book was released on 2015-07-31 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acrylamide in Food: Analysis, Content and Potential Health Effects provides the recent analytical methodologies for acrylamide detection, up-to-date information about its occurrence in various foods (such as bakery products, fried potato products, coffee, battered products, water, table olives etc.), and its interaction mechanisms and health effects. The book is designed for food scientists, technologists, toxicologists, and food industry workers, providing an invaluable industrial reference book that is also ideal for academic libraries that cover the domains of food production or food science. As the World Health Organization has declared that acrylamide represents a potential health risk, there has been, in recent years, an increase in material on the formation and presence of acrylamide in different foods. This book compiles and synthesizes that information in a single source, thus enabling those in one discipline to become familiar with the concepts and applications in other disciplines of food science. Provides latest information on acrylamide in various foods (bakery products, fried potato products, coffee, battered products, water, table olives, etc.) Explores acrylamide in the food chain in the context of harm, such as acrylamide and cancer, neuropathology of acrylamide, maternal acrylamide and effects on offspring and its toxic effects in tissues Touches on a variety of subjects, including acrylamide, high heated foods, dietary acrylamide, acrylamide formation, N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA), acrylamide removal, L-asparaginase, and acrylamide determination Presents recent analytical methodologies for acrylamide determination, including liquid chromatographic tandem mass spectrometry and gas chromatography-mass spectrometry
Download or read book New Frontiers in Acrylamide Study in Foods written by Marta Mesías and published by MDPI. This book was released on 2021-01-19 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The European Food Safety Agency (EFSA) has identified acrylamide as a public health concern due to its relation with the appearance of different types of cancer, and continued efforts are required to reduce exposure to acrylamide (EFSA, 2015). During the last few years, EFSA has maintained a high level of supervision to monitor the acrylamide levels in processed products, urging companies to implement effective mitigation strategies for reducing formation of this contaminant. Recently, the European Commission has published a regulation that sets mitigation measures for the reduction of this compound in foods, identifying new benchmark levels for a number of food categories (European Commission, 2017). The Regulation 2158/2017 compels food processors and food business operators in Europe to reduce the presence of acrylamide in their products, applying measures proportionate to the size and nature of the establishments. With the goal of providing information that contributes to our understanding for this process contaminant and exposure through dietary routes, this Special Issue explores the recent advances on the study of acrylamide in foods, including novel insights into the chemistry of its formation and elimination, effective mitigation strategies, conventional and innovative monitoring techniques, risk/benefit approaches, and exposure assessment.
Download or read book Toxicological Profile for Polycyclic Aromatic Hydrocarbons written by and published by . This book was released on 1995 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
